Ndeipi Basa rayo?
Kuvhiringidza ndechimwe chezvinhu zvinowanzokonzera marwadzo, asi zvakabatanidzwa nemarwadzo e fibromyalgia here?
Basa rekuvhiringidzika mumamiriro ezvinhu aya rave riri nyaya yekutsvakurudza uye kukakavadzana kwemakumi emakore. Chaizvoizvo, mamiriro acho akashandiswa kunzi "fibrositis," izvo zvinoreva "kuvhuvhuta-mavara." Nokufamba kwenguva, zvisinei, kuonekwa kusina kuvhuvhuta kwakaita kuti vezvechipatara vaone fibromyalgia ("fibrous-tishu uye kurwadziwa kwemisimba") sezwi rakarurama.
Makumi mashomanana gare gare, zvisinei, tiri kutarisa rwechipiri kutarisa mumamiriro ezvinhu aya, nokuda kwechikwata chinokura chebasa chinoratidza kuti chinogona kutamba basa, shure kwezvose. Iyi mutsara wekubvunzurudza inogona kutungamirira kukunzwisisa zviri nani chirwere pamwe nekuwedzerwa kurapwa kwarudzo.
Nei Chichivhiringidza?
Vanachiremba vakatenda kuti fibromyalgia yakanga isiri chirwere chinoputika nokuti hachiratidzi sechirwere chikuru chinopisa. Mapofu haaratidzi kuora kana kupisa. Mienzaniso yakafanana yezviputi zvinoputira, izvo zvinoratidzira kukwirira kwezvirwere zvakadai se lupus uye arthritis , kazhinji zvinoratidza zvakajairika kana kuti zvishoma chete zvakasimudzirwa mu fibromyalgia. Muna 2012, vatsvakurudzi vanoongorora kuputika kwemyopathies (marwadzo ezvinhu) akanyorwa kuti fibromyalgia "mhepathy yenhema."
Uyezve, zvinopesana nekuputira zvinodhaka-zvose corticosteroids uye zvisiri-steroidal anti-inflammatories (NSAIDs) -zviwanzo zvisingabatsiri pakuderedza marwadzo e fibromyalgia .
Saka nyaya yekuputika inopinda kupi?
The Case for Inflammation
Mumakore achangobva kupfuura, vatsvakurudzi vakadzidza zvakawanda pamusoro pekuvhiringidza kunogona kuita basa iri.
Muchirimo cha2017, Journal of Pain Research yakabudisa chidzidzo chakatarisa mapurotini akasiyana-siyana anokwana 92 ​​anozivikanwa kuti ane chokuita nekuputika.
Vatsvakurudzi vanoti ndeye "yakazara kwazvo ... kuvhiringidza kufungidzira kufungidzira kwevarwere veM FM kuti vauye." Vakataura hupupuriro hwakawanda hwekuputika. Kwete izvozvo chete, asi uchapupu hunoratidza kuvhiringidzika mukati mehutachiona hwehutano (uropi uye mitsipa yemutsipa wesipinha) pamwe ne systemic.
Basa iri rakatsigira zvidzidzo zvepakutanga zvichiratidza kuti mamwe malekoro kubva mumuviri wemuviri, anonzi cytokines , akakwirira kune vanhu vane fibromyalgia. Icho chinotsigira pfungwa yokuti ichi chiitiko chinosanganisira kuvhara ropa.
Iro remitambo yenherera ine muviri wayo wecune, wakatsaurwa kubva kune imwe yose yomuviri, uye chidzidzo chacho chakaratidza huwandu hwakawanda hwemasukiromu emakemikari anonzi chemokines, zvakare.
Chidzidzo che2010 neGenevra Liptan, MD, inoratidza kuti inogona kuva inofadza-yakatsetseka yezvigunwe zvinobatanidza zvakapoteredza zvivako zvemukati-izvo zvinoputika mu fibromyalgia. Mutsvakurudzi uyu anogumisa kuti kufadza kusagadzikana uye kuvhiringidzika kungave ndiko kunotungamirira kukurudzira kukuru , iyo inofungidzirwa kuti inonyanya kukosha kwechirwere chacho.
Central senitization inowanikwa apo nheyo yepamusoro yenheyo inova yakasimudzirwa uye inopindirana-inopindira kune zvinyorwa, kusanganisira kurwadziwa nezvimwe zvinhu zvinoonekwa nemanzwi ako, zvakadai sechiedza, ruzha , nezvinonhuwira .
Zvinotendwa kuti zvishoma nezvishoma zvinokonzerwa nemarwadzo anoramba achiita bombarding brain and spinal cord.
A 2012 kuongorora muNeuroimmunomodulation yakatsvaga basa rekuti zvinogona kuitika zvinokonzera kuvhiringidza uye kugadzikana kwepfungwa mu fibromyalgia. Vatsvakurudzi vakaona kuti kwaiva nehupfumi hwehurumende hwakanga hwakaita kuti husungirirwe nekusagadzikana kusinganzwisisiki kudzvinyirira. Vakanga vasingakwanisi kuziva kana kupisa kunokonzera kushushikana kwekutadza kushanda kana zvakasiyana.
Muna 2013, vatsvakurudzi veSpain vanotungamirirwa neMDC Cordero vakabudisa pfungwa yokuti kuputika mu fibromyalgia kunogona kukonzerwa nekushaya simba mukati me mitochondria (zvikamu zvemasero ako anoputsa zviratidzo kuti aumbe simba.) Chimwe chidzidzo 2010 kubva kuSpain, chakabudiswa mu Clinical Rheumatology , yakaratidza hupamhi hwemast cells-iyo inosunungura makemikari ekuvhiringidza mumagadzirirwo akasiyana-siyana-muganda revanhu vane fibromyalgia.
Kurapa Kurwiswa muFibromyalgia
Sezvo mishonga yokurapa-steroid uye NSAIDs-yakatove yakaratidzwa isingabatsiri pakurwadziwa kwe fibromyalgia, ndezvipi zvatinogona kuita pakuderedza kutuka kwedu uye, tichivimba semagumisiro, marwadzo edu?
Chidzidzo che 2017 chakaratidza kuti mishonga inonzi " low-dose" naltrexone (LDN) inogona kubatsira kuderedza zvimwe zviratidzo zvekuvhiringidza, izvo zvinoratidzika kubatsira kubatsira kuderedza kurwadziwa nezvimwe zviratidzo.
Liptan yekudzidza 2010 pamusoro pekuputika kwepashoko inoratidza kuti mazano ekurapa anotarisa faira anogona kunge akabudirira. Izvo zvinosanganisira myofascial release ( rudzi rwemisi inoshambadza ) uye kushandiswa kwakadzika-mavara kunonzi Rolfing. Zvisinei, kusvika ikozvino, kutsvakurudza pamusoro pemishonga iyi yakakosha. Uyewo, zvichienderana nezviratidzo, vamwe vanhu vane chirwere ichi vangasazokwanisa kuregerera mamwe marudzi ekusimbisa.
Chidzidzo che2012 chakabudiswa muScandinavia chinoratidza kuti kudzidzira kwemvura kunogona kuvandudza urongwa hwe cytokine mu fibromyalgia, uye naizvozvo kudzikira kwepamusoro kunokonzera uye kurwadziwa. (Usati watanga chero rudzi rwemhando yekurovedza muviri, zvakakosha kudzidza pamusoro penzira yakakodzera yekudzidzira ne fibromyalgia .)
Vamwe vanhu vane fibromyalgia vanoti vane ruzivo rwakawanda nemishonga inowedzera kutenderera. Anti-inflammatory supplements inosanganisira:
Hatisati tatsvakurudza nezvezvokudya zvinopesana nokuputira zve fibromyalgia, asi vanachiremba vakawanda vanokurudzira kuti zvive zvekuvhiringidza. Nemhaka yokuti havasi vanhu vose vanokonzera kuvhiringidza vakafanana, vanhu vanowanzotanga nezvokudya zvisinganyanyi kurongeka, uye kuwedzera zvakare mune imwe mhando yezvokudya nenguva yekuziva kuti zvipi zvokudya zvinonetsa.
Shoko kubva
Sezvatinodzidza zvakawanda pamusoro pebasa rekuputika mu fibromyalgia, tinogona kuzarura zvinangwa zvitsva zvemishonga nemamwe mishonga, uye izvozvo zvinogona kutungamirira kune nzira dzakanakisisa dzokurapa mumugwagwa.
Hatizivi kuti basa rekuvhiringidza rakakura sei, kana kuti chiri chikonzero kana chikonzero chechiitiko chacho. Iyi ndeye mibvunzo inogona kupindurwa sezvo mitsara yekutsvakurudza inoenderera mberi kuongororwa.
Sources :,
Backryd E, Tanum L, Lind AL, Larsson A, Gordh T. Journal of pain pain. > 2017 Mar 3; 10: 515-525. doi: 10.2147 / JPR.S128508. Uchapupu hwehutachiona hwehutachiona uye neuroinflammation muvarwere ve fibromyalgia, sekuongororwa ne multiplex protein panel inoshandiswa kune cerebrospinal fluid uye plasma.
Blanco I, et al. Clinical rheumatology. 2010 Dec; 29 (12): 1403-12. Kunyanyisa kufungisisa kwemastocytes muhuputi hweganda revigromyalgia varwere.
Bote ME, et al. Neuroimmunomodulation. 2012; 19 (6): 343-51. Kuvhiringidza / kushushikana kwepfungwa kudzvinyirira mune vakadzi vane fibromyalgia.
> Cordero MD, uye al. Antioxidants & redox kuisa. 2013 Mar 1; 18 (7): 800-7. Kuputika kune mitochondrial inokonzerwa nekusavhiringidza kwechiitiko mune fibromyalgia here?
> Liptan, GL. Zvinyorwa zve bodywork uye kufamba kwemishonga. 2010 Jan; 14 (1): 3-12. Fascia: Iko kusina kunobatanidza kunzwisisa kwedu kwehutachiona hwe fibromyalgia.