Rheumatoid Factor Test Test: Rinocherechedzai?

Rheumatoid Factor Inonyanya Kuonekwa Muvanhu Ane Rheumatoid Arthritis

Rheumatoid chinhu inonzi immunoglobulin (antibody) inogona kusunga kune dzimwe zvirwere. Kazhinji, zvirwere zvinoputika zvipuroteni zvakajairika zviri muropa iro rinoshanda mukati memagadzirirwo ezvirwere . Rheumatoid factor, zvisinei, hazviwanzowanika muhuwandu hwevanhu. Kunyange zvazvo inongowanikwa munenge 1-2 muzana yevanhu vane hutano, chiitiko cherhumumasi chinowedzera nezera uye vanenge 20 kubva muzana yevanhu vanopfuura makore makumi matanhatu nemakore makumi mashanu vane nhepfenyuro yakakwirira.

Kuvapo kwerumatoid factor kunowanikwa neropa rekuongorora. Kuongorora ropa kunowanzorairwa kana rheumatoid arthritis inofungidzirwa. Rheumatoid chinhu iripo muzana makumi mapfumbamwe evanhu vakuru vane rheumatoid arthritis, asi kune huwandu hwakaderera muvana vechirwere rheumatoid arthritis. Chiitiko cherumatoid chinowedzera nehuwandu hwezvirwere mu rheumatoid arthritis: pamwedzi mitatu chiitiko cha 33 muzana, asi gore rimwe chete chikamu 75 muzana. Kusvikira 20 muzana yehutukutu hwemapfupa arthritis vanogara vasina kunaka nehumuhutachi chinhu munguva yese yezvirwere zvavo. Vanhu avo vasina hanya nedheumatoid factor inorondedzerwa sevanonzi seronegative rheumatoid arthritis.

• Seronegative uye Seropositive Rheumatoid Arthritis

Mamwe Mamiriro Ezvinhu Angave Akabatanidzwa Nezvakanaka Rheumatoid Factor Test

Zvimwe zvirwere zvinokonzerwa nehutachiona zvinogona kuva zvakanaka kune rheumatoid chinosanganisira:

• Sjogren's syndrome
• Systemic lupus erythematosus
• Scleroderma
• Polymyositis
• Dermatomyositis
• Mixed Connective Tissue Disease

Zvimwe zvirwere kana mamiriro ezvinhu anogona kuenzaniswa nehutachiona hunokonzerwa nemigumisiro yechiratidzo inosanganisira:

• Bacterial endocarditis
• Osteomyelitis
• Tuberculosis
• Syphilis
• Hepatitis
• Mononucleosis

• Kuparadzanisa kupindirana kwepermonary fibrosis
• Chiropa cirrhosis
• Sarcoidosis

Mamiriro Evanhu Haasanganiswi neRheumatoid Factor

Rheumatic conditions iyo isingabatanidzwi nepamusoro yehemu yepamuti inosanganisira:

• Osteoarthritis
• Ankylosing spondylitis
• Gout
• Psoriatic arthritis
• Reiter's syndrome / Reactive arthritis

High Titer Rheumatoid Factor

Mhando dzepamusoro kana mazita echirwere chemukoko chinowanzobatanidzwa nehutachiona rheumatoid arthritis. Rheumatoid chinhu chave chave chichibatanidza netsika yakakwirira yekukudziridza zviratidzo zvisingabatanidzi (extra-articular) zvechirwere, zvakadai sedheumatoid nodules uye rheumatoid lung disease.

Rumatoid Fact Factor Inofanirwa Sei?

Chiyero cherhumatoid chinokonzerwa neropa chinogona kuyerwa ne:

Agglutination tests

Imwe nzira inosanganisa ropa remurwere neine midzi ye latex yakafukidzwa nemaviri evanhu (IgG). Irosikiti machira clump kana agglutinate kana rheumatoid factor (IgM RF) iripo. Imwe nzira inosanganisa ropa remurwere nemakwai masero matsvuku eropa akave akafukidzwa nemarangi anorwisa. Masero matsvuku eropa anobata kana rheumatoid chinhu iripo.

A titer inoratidzira yekuti agglutination test test yegazi inogona kuderedzwa sei mushure mokunge rhumumato isingaoneki.

Inenge ya1:20 inoratidza kuti rhumatoid factor inogona kuonekwa apo chikamu chechiropa chinoderedzwa kusvika kusvika kumativi makumi maviri e saline. Zvichienderana nebasa racho, kukosha kwerhumatoid chinhu che1:20 kana zvishoma kunofanirwa kufanana.

Nephelometry test

Ropa revarwere rinosanganiswa nemasikirwo anokonzera kuti ikonze kana rheumatoid chinhu iripo. Chiedza chinopfurikidza nehuputi ine chisanganiswa uye chiridzwa chinotarisa kuti chiedza chakavharidzirwa sei musanganiswa. Nhamba dzakakwirira dze rheumatoid chinokonzera mazamu akawanda uye inobvumira chiedza chiduku kudarika, chakayerwa mumakamuri. Zvichienderana nebasa racho, kukosha kwerheumatoid chimwe chema 23 kana zvishoma masuniti kunofanirwa kufanana.

Paunenge uongorora mazano eB lab, yeuka kuti chirwere chemukoko chinodarika masuniti makumi maviri nemaviri uye chinotapira kupfuura 1:80 chinoratidza rheumatoid arthritis asi chinogonawo kuitika kune mamwe mamiriro. Mhedzisiro yakaipa inogona kuitika kana uwandu hwemafuta muropa hwakakwirira. Migumisiro isina kururama inogona kukonzerwa nekusakodzera kushandiswa kwemuenzaniso weropa. Uye pakupedzisira, chirwere chisingaiti chetachiona chechirwere hachiregi kutarisa rheumatoid arthritis.

• Rheumatoid Factor - Kunzwisisa Muongorori Wemigumisiro

_Sources:

_{Rheumatoid Arthritis: Kuziva Kukura Kwekare uye Kuporesa. Kushi, Weinblatt, uye Cavanaugh MD Professional Communications, Inc. Chechitatu.}

_{Todd-Sanford: Clinical Diagnosis ne Laboratory Laboratory.}