Psoriatic Arthritis

Pfungwa yePororiatic Arthritis

Psoriatic arthritis chirwere chinoputika cheArthritis chinosangana ne psoriasis (chirwere cheganda) uye zviratidzo zvisingagumi zviratidzo. Zviratidzo zve psoriasis uye kuvhiringidza kwekubatana zvinowanzobudirira zvakasiyana. Muna 85 muzana yevanhu vane chirwere ichi, zviratidzo zve psoriasis zvinotangira zviratidzo zveArthritis. Arthritis inotangira pamberi pe psoriasis kusvika kusvika 15 muzana yevaya vane psoriatic arthritis.

> Kutarisa psoriatic arthritis pamwe neminwe uye mberi.

Maererano neCDC, vanhu vakuru vanosvika mamiriyoni 6.7 muUnited States vane psoriasis. Muvanhu vane psoriasis, vanenge 15 muzana vanoita psoriatic arthritis. Kuwandisa kwayo chaiyo hakuzivikanwi, asi kwakambofungidzirwa kuva pakati pe3.3% kusvika 1 muzana yevanhu. Nguva yekutanga kweporioriyamu arthritis inowanzova pakati pemakore makumi matatu nemakumi mashanu emakore, asi inogona kukura chero ipi zvayo. Varume nevakadzi vanobatanidzwa zvakafanana.

• Zvaungaziva Nezve Otezla (Apremilast)

• Stelara IInjectable Drug yePaque Psoriasis uye Psoriatic Arthritis

Zviratidzo Zvinowanikwa nePororiatic Arthritis

Zviratidzo zvinosangana nemapiroriyamu arthritis zvinowirirana pane zvazvinoitika uye mapepa anowanikwa. Chero hupi hupi mumuviri hunogona kuchinjwa nemarwadzo uye unyoro. Panogona kunge kune kuoma uye kuoma kushandura manhengo ane hutano kuburikidza nehutano hwavo hwemazuva ose. Vamwe vanhu vane chirwere chinosangana nekuoma kwemangwanani kunopedza nguva inopfuura hafu yeawa. Apo psoriasis inobatanidzwa, pane zvipembenene zvezvitsvuku, zvitsvuku, zvinokwidziridzwa, kana zvikavara zveganda. Nail kusina kunaka kunogona kuonekwa sepitting uye yakasimbiswa kana yakarongedzwa neminwe. Zvimwe zviratidzo zvinowanzobatanidzwa nemapiroriyamu arthritis zvinosanganisira kuneta, kuvhuvhuta kwemaoko akafanana neminwe uye zvigunwe (dactylitis), tendinitis , enthesitis, kurwadziwa kunorwadza shure , uye conjunctivitis .

• Zviratidzo nezviratidzo zvePororiatic Arthritis

Mhando dzePoriori Arthritis

Psoriatic arthritis ndeyeboka rezviitiko zvinonzi spondyloarthropathies . Pane mashanu anozivikanwa marudzi e psoriatic arthritis anosiyaniswa nezviratidzo. Mhando shanu, iyo inogona kudarika, ndeyi:

• Symmetric Psoriatic Arthritis inokanganisa mafundo kumativi maviri omumuviri (semuviri, mabvi maviri ose, zvose zviuno), uye kazhinji inobata majoka akawanda (polyarthritis) . Izvo zvakafanana nerheumatoid arthritis asi inowanzova yakaoma uye isisina kuora. Inenge 25 muzana ye psoriatic arthritis varwere vane chirwere ichi.
• Asymmetric Psoriatic Arthritis haibatsiri maitiro akafanana kumativi maviri omumuviri. Chero chibatanidzwa chinogona kuchinjwa, zvakadaro. Kuita-kutaridzika kwakaita seminwe yeminwe nezvigunwe zvakajairika. Majoini angave ari matsvuku, ashambidzika, akazvimba, uye anorwadza. Kazhinji inofungidzirwa sechimiro cheporioriyamu arthritis, inogona kuve yakaremara kune vamwe vanhu. Inenge 80 muzana yevanhu vane psoriatic arthritis vanobatwa nehutachiona hwechirwere ichi.

• Distal Interphalangeal Predominant (DIP) Psoriatic Arthritis inoonekwa se "classic type," maererano neNational Psoriasis Foundation, kunyange zvazvo inenge inenge 5 kusvika ku10 muzana yevaya vane psoriatic arthritis. Zvimwe zvikamu zvemufananidzo uyu we psoriatic arthritis ndekubatanidzwa kwezvinyorwa zvakasiyana-siyana zveminwe uye zvigunwe (iyo yejoka iri pedo nemisungo), uyewo uchapupu hwehupi hunochinja.
• Spondylitis Type of Psoriatic Arthritis ine kuputika kwepamusoro sechiratidzo chikuru. Vanenge 5 kusvika ku20 muzana yevanhu vane psoriatic arthritis vanobatwa ne spondylitis rudzi. Inenge hafu yevaya vane spondylitis vakanaka kune HLA-B27 , genetic marker.
• Arthritis Mutilans Type of Psoriatic Arthritis inonzi yakasimba, inodzivisa, uye isingawanzoitiki. Pasina 5 muzana yevanhu vane psoriatic arthritis vanobatwa. Kuwirirana kunobatanidza arthritis mutilans nemajoka maduku emaoko nemakumbo akabatanidzwa. Uturu hwemitsipa uye kurwadziwa kwepamusoro kwepamusoro kunobatanidzwawo nemhando iyi ye psoriatic arthritis.

Kuongororwa kwePororiatic Arthritis

Hapana chiyeuchidzo chimwe chete chinoshandiswa kuongororesa psoriatic arthritis. Kuongorora kwepanyama, x-rays, uye MRI zvinoshandiswa kubatsira kusimbisa kuongororwa. Kuongorora ropa kunowanzoshandiswa kutonga kunze kwemamwe marudzi eArthritis ane zviratidzo zvakadai, rheumatoid arthritis, gout, reactive arthritis , ankylosing spondylitis , uye osteoarthritis .

Kunyange zvazvo zvimwe zvikamu zve psoriatic arthritis zvakafanana nedzimwe mhando dzeArthritis, maronda emaperembudzi, misungo yemakumbo, uye maitiro ekuputika anozviparadzanisa kubva kune zvimwe zvinokonzera kurwara kweArthritis. Pangosvika kuongororwa kunosimbiswa nachiremba, kurapa kwakakodzera kunogona kutanga. Kunyanya kuongororwa uye kurapwa kwekutanga kwakakosha kuunza chirwere ichi kutungamirirwa, kupa mikana yakanakisisa yekudzivirira hurema, zvirwere zvekuwedzera, uye kusagadzikana kwekugara pamwe chete.

• Kuongorora uye Kuongororwa kwePororiatic Arthritis

Kurapa kwePororiatic Arthritis

Nemhaka yokuti psoriatic arthritis inosanganisira zvose zviratidzo zveganda uye pamwe chete zviratidzo, chinangwa cherongwa hupi hwehutano rinofanira kuva nechinangwa chechipiri.

• Cosentyx: Kurapa Option yeAnkylosing Spondylitis uye Psoriatic Arthritis

• Kudya Kwezvokudya Kunogona Kubatsira Psoriatic Arthritis

Rheumatologist yako inotarisa chirwere chakakomba pakusarudza kurapwa, pamwe nekufungisisa kuve nekukanganisa kwechimwe chirwere pane zvimwe zvikamu zvechirwere. Somuenzaniso, mushonga unosarudzwa kuti utarise zviratidzo zveArthritis kubatsira kana kukuvadza ganda here re psoriatic arthritis? Zvinyorwa zvinokonzerawo kusarudza kurapwa.

Kazhinji, NSAIDs (nonsteroidal anti-inflammatory drugs) ndiyo mishonga yemutsara yekutanga kune vanhu vane zvirwere zvepachirwere chetachiona. Kune vanhu vane maekirwoti ekuratidza zvirwere zveArthritis zvakanyanya, vasingateereri zvakanaka kune NSAIDs chete, DMARDs (zvirwere-kuchinja anti-rheumatic drugs) , zvakadai se methotrexate kana Arava (leflunomide) , inogona kushandiswa. Biologic zvinodhaka , zvakadai seTNF blockers , zvakakodzera kuvanhu vane zvirwere zvakakomba (semuenzaniso, uchapupu hwekushandura, masangano akawanda anokanganisa, kukanganisa kushanda kwakanyanya ). Corticosteroids inowanzoshandiswa kushandiswa kweporiorian arthritis.

Kana zviratidzo zveganda zvakakurumbira, zvichida zvakaenzana zvakanyanya sezviratidzo zvekubatana, mishonga inokwanisa kutonga zvose zviri zviviri. TNF blockers inoonekwa sehutano hwehutano hweganda pamwe nekubatana pane zve psoriatic arthritis. Methotrexate, photochemotherapy, PUVA, retinoic acid, uye cyclosporine A inogona kubatsira zvose zveganda uye pamwe chete.

Kune mishonga mitsva inowanika ye psoriatic arthritis inogona kufungwa, zvakare:

• Otezla (apremilast)
• Cosentyx (secukinumab)
• Stelara (ustekinumab)

Kuwana Kudzora Pamusoro pePororiatic Arthritis

Zvinofadza kuti pane imwe nguva, psoriatic arthritis yaifungidzirwa kuva chirwere chinyoro. Zvechokwadi, psoriatic arthritis yakanyanya kukura kudarika pakutanga yaifungidzirwa. Kubvumirana kwemasayenzi ezvesayenzi kwakaratidza kuti, maererano nekukuvara kwekubatana, huwandu hwehurombo hunobatanidza:

• Nhamba yepamusoro yezvibatanidzi nekukurumidza kuputika
• Yakakura sedimentation rate uye CRP
• Kuparadzanisa kwakakwana kunoonekwa pa-ray-rays
• Kusakwanisa kuwana mhinduro yakakwana nemimwe mishonga
• Kushanda kwemiganhu
• Utano hwakashata hwehupenyu

Kuti uwane simba pamusoro pe psoriatic arthritis, zvakakosha kuti iwe uongororwe, uongororwa, uye unorapwa neRheumatologist . Vanhu vane psoriatic arthritis vanogamuchira kurapwa kwepamberi vane mukana wakanakisisa wekutarisa kufambira mberi kwechirwere uye kusanganisa pamwe. Iyo inozivikanwa zvakare kuti psoriatic arthritis inobatanidza ne comorbidities, kuwedzera kwekuda kwezvinetso, uye kuwedzerwa kufa-chimwe chikonzero nei kurapwa kwekutanga kuchikosha.

• Psoriatic Arthritis Matambudziko

Kugadzirisa psoriatic arthritis kubudirira kunoda kuti iwe uite maererano neurongwa hwako hwekurapa, kurovedza muviri, kushandisa maitiro ekudzivirira pamwe, kuchengeta hutano hwako hwakakwana, uye kutarisira comorbidities (semuviri, cardiovascular disease).

Shoko Rinobva

Psoriatic arthritis yave ichinzi ihwohwo inopesana nehosha yeArthritis nekuda kwekushamwaridzana ne psoriasis. Izvozvo, pamwe chete nezvimwe zvinetso uye zvinokonzerwa ne comorbid conditions, zvinoita kuti zvive zvakafanira kuti mushonga unoshanda hurumidze kufamba. Chinangwa chevanhu vane psoriatic arthritis ndechokutarisa chirwere ichi uye kuisa mararamiro ayo kune hupenyu hwehupenyu. Iko, takakugadzirira iwe zvinyorwa zvaunoda kuziva nezve psoriatic arthritis. Uzivo ihwohwo huchakubvumira kuti unzwisise mirayiridzo yechiremba wako, kugadzira mibvunzo kukumbira chiremba wako, uye kukurudzirwa nemishonga yekurapa inoshandiswa, kusanganisira zvimwe zviri zvitsva.

> Sources:

> Gladman DD et al. Psoriatic Arthritis: epidemiology, makiriniki, maitiro, nemigumisiro. Annals weRheumatic Disease. 2005; 64: ii14-ii17

> Gladman DD uye Ritchlin C. Zviratidzo zveKliniki uye Kuongororwa kwePororian Arthritis. Kusvika pari zvino. Updated 02/12/16.

> Gladman DD uye Ritchlin C. Mumiririri Information: Psoriatic Arthritis (Beyond the Basics). Kusvika pari zvino. Kushandurwa 04/13/16.

> Helmick CG et al. Kuwanda kwePororiasis Pakati pevanhu vakuru muUnited States 2003-2006 uye 2009-2010 National Health and Nutrition Examination Surveys . American Journal of Preventive Medicine . 2014.

> Psoriatic Arthritis, American College yeRheumatology. Svondo 2013.