Chirwere cheRyme chinokonzerwa nehutachiona kubva kubhakitiriya Borrelia burgdorferi . Vanhu vanogona kuwedzera chirwere ichi mushure mekunge varovwa nehutachiwana. Maererano neCenters for Disease Control and Prevention (CDC), chirwere cheLyme hachigoni kupararira pabonde, kana nekutsvoda kana kunwa kunze kwegirazi imwechete semunhu ane chirwere cheLyme. Pane zviitiko zvekuparidzirwa kubva kumunhu kusvika kune munhu kana mhuka kumunhu; inoparidzirwa chete nemashizha.
Mitikiti
Iwe haufaniri kufunga kuti uri mungozi yehosha yeLyme nekuda kwekugara kwaunoita. Kunyange zvazvo zviitiko zvizhinji zvichibva kune imwe nzvimbo yehurumende, chirwere chinobata chikamu chose cheUnited States. Uye yeuka: Kunyangwe dambudziko rako rekukwezva rinogona kunge rakaderera paunopinda musuo rako, zvinogona kunyanya kuenda kana uchienda kunofara.
Lifestyle Risk Factors
Pane humwe hupenyu hwehutano hunokonzerwa nekubatanidza maikiti uye, nokudaro, kune unogona kubvumirana nechirwere cheLyme. Izvi zvinosanganisira:
- Kuva muvhimi
- Kuva nemhuka
- Kurarama kumaruwa
- Kurarama mukati, kushanda mukati, kana kuenda kune imwe yenhokwe dzinoputika muUnited States (Northeast, Mid-Atlantic, kana North North Central)
- Kupedza nguva muhuni kana munzvimbo dzakasvibira
- Kuva nebasa rekunze
Genetics
Kunyange zvazvo chirwere cheLyme hachisi chemajini, unogona kugara nhaka mazamu anoita kuti zvive nyore kuti iwe uone zviratidzo zvakanyanyisa kana uchibata chirwere cheLyme.
Chirongwa chikuru chemajeni chechirwere cheLyme chinofungidzirwa kuti chiri mune zvimwe zvakasiyana zvekirasi yechipiri maitiro ake makuru e-histocompatibility complex (MHC). MHC iripo pfupi pfupi yekromosome 6. Inosanganisira kirasi I, II, uye III MHC yegene, imwe neimwe inobata maitiro ezvirwere zvemuviri. Girasi yechipiri yechipiri inobatsira pakuita antigen-specific T chengetedza mhinduro.
Pane humwe hutachipiri hweHLA gene mararamiro (genotypes) -HLA-DR4 uye HLA-DR2-iyo yakabatanidzwa pakubatanidzwa muRyme arthritis. Ive yakarongedzwa kuti kana kamashikiti kacho kacho katachiona kaRyme chichienda kune majointano, maitiro ezvirwere zvemusununguko pamusoro payo-anogadzikana nemunhu akabatanidza tissue kune vanhu vane HLA-DR4 neHLA-DR2, zvichiita kuti vaite zvekuzvimirira uye vachigadzira zvimwe arthritis yakaoma.
Vanhu vane chirwere cheLyme zvakanyanya uye vasingateereri zvakanaka kurapwa kwemishonga inorwisa mabhakitiriya vanowanzowanikwa kuti vane DRB1 * 0101 uye 0401 yechikoro chechi genotypes, iyo inoratidzawo kuti zvinogadzirisa zvigadziriswe. Kutsvakurudza kunopfuurira kuri kuitika pahukama pakati pezvirwere uye chirwere cheLyme.
Post-Treatment Lyme Disease Syndrome
Mushure mokurapa, nhamba shomanana yevanhu ichakura zviratidzo zvinoramba zvichiripo, izvo vamwe vanotaura se "chisingaperi" chirwere cheRyme . Iko kugadzirisa kukakavara. Kunyange zvazvo CDC ichibvuma kuti zvimwe zviratidzo zvinogona kuramba zvichiitika mushure mekunge kurapwa kwapera (zvakadai sekurwadziwa kwejodzi uye neuropathy), zviratidzo izvozvo zvinenge zvigadziriswa pasi rose mumwedzi mitanhatu kana kupfuura. Kupfuura nguva iyoyo, pane uchapupu hushoma hwokuti zviratidzo zvinoramba zvichiripo-kunyanya kusagadzikana kusingaperi-zvakabatana zvakananga nehutachiona hunopfurikidza naBrrelia burgdorferi .
Kune vanhu ava, CDC yakaronga chirwere ichi sechishandisire Lyme disease syndrome (PTLDS). ICDC inonyevera kurwisa kwenguva yakareba kurapwa kwemishonga yekurapa kwe PTLDS.
> Sources:
> Brewer JH, Thrasher JD, Hooper D. Chirwere Chisingaperi Chinobatana neMold uye Mycotoxins: Is Naso-Sinus Fungal Biofilm muCulprit? Toxin. 2014; 6 (1): 66-80. doi: 10.3390 / toxins6010066.
> Brewer JH, Thrasher JD, Straus DC, Madison RA, Hooper D. Kuongorora maMycotoxin muvarwere vane Chronic Fatigue Syndrome. Toxin . 2013; 5 (4): 605-617. doi: 10.3390 / toxins5040605.
> Kalish RA, Leong JM, Steere AC. Association of Treatment-Resistant Chronic Lyme Arthritis NaHLA-DR4 uye Antibody Reactivity kuOspA uye OspB yeBorlialia Burgdorferi. Utachiwana uye Kusagadzikana . 1993; 61 (7): 2774-2779.
> Strle K, Shin JJ, Glickstein LJ, Steere AC. A Reoll-Like Receptor 1 Polymorphism Inobatanidza neHeightened T-mubatsiri 1 Mhinduro dzeKubvumira uye Antibiotic-Refractory Lyme Arthritis. Arthritis uye Rheumatism . 2012; 64 (5): 1497-1507. doi: 10.1002 / art.34383.
> World Health Organization (WHO). Mycotoxins . Yakabudiswa muna October 2011.