Dambudziko reAlzheimer Treatment
Kuongorora kunova, uye iri chirwere cheAlzheimer . Iwe unganzwa uchitya, uchinetseka, uchisunungurwa, kana unogona kunge usina kungoda kuzvitenda. Saka zvino chii? Kunyange zvazvo pasina chirwere cheAlzheimer panguva ino, pane nzira dzakawanda dzokurapa zviratidzo . Mishonga inoshandiswa inosanganisira zvinodhaka remishonga uye zvisingashandisi zvinodhaka, zvakadai sekuchinja uye kuchinja kwezvakatipoteredza.
Kurapa Kwezvinodhaka Kwemagariro Anonzwisisa
Kuziva nezvekugadzirisa zvinokonzerwa nemishonga inoedza kupedza kuwedzera kwezviratidzo zveAlzheimer .
Kunyange zvazvo mishonga iyi ichiita seinovandudza mafungiro emamwe vanhu, kubudirira kwese zvakasiyana zvikuru. Mafungiro ekugadzirisa matambudziko anofanira kuongororwa nguva dzose nekuda kwemigumisiro uye kuwirirana nemimwe mishonga.
Makirasi maviri emishonga akagamuchirwa neU.S. Food and Drug Administration pakurapwa kwezviratidzo zvekuziva nezveAlzheimer's. Zvinosanganisira cholinesterase inhibitors uye N-methyl D-aspartate (NMDA) vadzivisi.
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Inofanirwa Kuendesa Mberi Inoshandiswa Kurapa Kushungurudzika muAlzheimer's?
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Inonzi Snoezelen Therapy Inobatsira Here muAlzheimer's Disease?
Chikoro 1: Cholinesterase Inhibitors
Cholinesterase inhibitors inobata nekudzivirira kuparara kweacetylcholine muuropi. Acetylcholine ikemikari inobatsira nerve cell sekutaurirana munzvimbo dzekuyeuka , kudzidza, nemamwe mano ekufunga. Tsvakurudzo yezvesayenzi yakawana mashoma emakero e-acetylcholine muhupano hwevanhu vane Alzheimer's, saka tariro ndeyokuti nekudzivirira kana kuwedzera mazinga acetylcholine kuburikidza nemishonga iyi, huropi huchaita huchadzikama kana hunovandudza.
Vanotsvakurudza vanofungidzira kuti kune vanenge makumi mashanu kubva muzana yevanhu vane Alzheimer vanotora cholinesterase inhibitors, kuwedzera kwezviratidzo zveAlzheimer kunonoka kusvika pamusana wemwedzi mitanhatu kusvika kumwedzi.
Pane zvitatu zvinoshandiswa mumitambo inhibitor ikozvino inogamuchirwa uye inorayirwa kurwara chirwere cheAlzheimer:
- Aricept (donepezil) : Yakagamuchirwa kuva munyoro , kuenzanisa , uye yakaoma Alzheimer's
- Exelon (rivastigmine) : Yakagamuchirwa kuti unyatsorevedza Alzheimer's
- Razadyne (galantamine): Yakagamuchirwa kuva munyoro kuenzanisa neAlzheimer's
Nenzira, Cognex (tacrine) yakanga yapfuura FDA yakagamuchirwa kuti ive nekodzero yekuenzanisa yaAlzheimer's; zvisinei, haisi kutengesa zvakare nemuumbi wayo nokuti yakakonzera mamwe matambudziko makuru.
Chikoro 2: N-Methyl D-Aspartate (NMDA) Antagonists
Namenda (mementine) ndiyo chete mishonga ino mukirasi ino, uye inogamuchirwa kuti ienzanise kuAlzheimer's severe. Namenda inoratidzika kushanda nekuronga glutamate (anino amino acid) muuropi. Maitiro anowanzoitwa glutamate anoita kuti kudzidza kuvepo, asi kuwandisa kunogona kukonzera masero europi kuti afe.
Namenda yave yakagadzirisa zvakananga mukukanganisa kufambira mberi kwezviratidzo mune chirwere cheAlzheimer gare gare.
Zvinodhaka Zvinodhaka
Muna 2014, FDA yakabvumira Namzaric, iyo inosanganiswa yefrepezil uye mutezo-mumwechete kubva kumakamuri ese pamusoro.
Iyo yakasarudzwa kuti ienzane nehosha yakaoma yeAlzheimer's.
Kurapa Kwezvinodhaka Kwekuita Maitiro, Mafungiro Epfungwa Neomumwoyo (BPSD)
Psychotropic mishonga inoshandiswa pane dzimwe nguva kuratidzira maitiro, maitiro epfungwa, uye maonero eAlzheimer's disease. Zviratidzo izvi zvinosanganisira kushungurudzika mupfungwa , kuora mwoyo, kuzvidya mwoyo , kusuruvara , kukanganisa , uye paranoia , pamwe nemamwe mafungiro akaoma , saka kuve nekushingaira mukuzviziva uye kuvabata kunokosha.
Kirasi yemishonga inonzi psychotropic inosanganisira antidipressants, anti-anxiety medication, antipsychotics , mafungiro ekusimudzira , uye mishonga yekushaya hope (dzimwe nguva inonzi kurara mapiritsi kana hypnotics ). Iyi mishonga inogona kuva yakakosha asi inogonawo kukonzera kukanganisika kwemigumisiro. Psychotropics inowanzoshandiswa pamwe chete nedzimwe nzira dzisingashandisi zvinodhaka kana mushure mekuedza kusina mishonga yekurapa uye kuzviwana kuti hazvina kukwana.
Zvisingabatsiri Zvinodhaka Zvinokonzera Maitiro, Mafungiro Epfungwa uye Emotional Symptoms
Zvisiri-zvinodhaka zvinoshandiswa zvinotarisa pakurapa maitiro, maitiro epfungwa, uye maonero eAlzheimer nekuchinja nzira yatinonzwisisa nekubatana nemunhu ane Alzheimer's.
Aya maitiro anoziva kuti mufambiro kazhinji inzira yekukurukura kune avo vane Alzheimer's. Chinangwa chekusava kushandisa zvinodhaka ndiko kunzwisisa zvinorehwa nemitemo yakaoma uye kuti nei varipo.
Zvisiri-zvinodhaka zvinoshandiswa zvinowanzotanga kushandiswa tisati tashandisa mishonga inonzi psychotropic, sezvo isina mikana yemigumisiro kana kupindira kwemishonga.
Maitiro ekuongorora
Ziva imwe tsika uye ona kuti chii chinoita sechichiita mufambiro . Semuenzaniso, kana howa nguva dzose ichiita kuti mudiwa wako agumburwe , edza kushamba panzvimbo. Kana kuedza kupa mvura pane imwe nguva yezuva. Panzvimbo yekushandisa mishonga kana mumwe munhu atsamwa kana kushungurudzika, nzira isina kushandisa zvinodhaka inoedza kunzwisisa kuti nei vachigona kugumburwa . Zvichida vanoda kushandisa imba yekugezera, vari mukurwadziwa , kana kuti vanofunga kuti vakarasika chimwe chinhu. Cherechedza izvo zvinoitika pamberi pemaitiro, edza chimwe chinhu chakasiyana nenguva inotevera, uye tarisa mhinduro.
Iwe unogona kazhinji kudzivisa mafambiro anonyanya kukuvadza nokuchinja maonero ako.
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Unoita Maitiro Anodzivirira Kubatsira Kuderedza Kushungurudzika uye Kuzvikudza muDementia?
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Chidzidzo Chinosimbisa Nzira Yokutenderera Kushandura Dambudziko reAlzheimer
Somuenzaniso, kana mudiwa wako achikumbira kuona amai vake (avo vangangodaro vafa kwemakore akawanda), kumbirai kuti akuudzei pamusoro pake, pane kumumanikidza kuti atarise kufa kweamai vake. Izvi zvinonzi chirongwa chekugadzirisa , uye inogona kuva yakakosha mukunyaradza munhu anenge atsamwa.
Vanhu vanogara nehutano hwemararamiro vanogona kunzwa vakasurukirwa kana kuvhiringidzika dzimwe nguva, uye vangave vasingakwanisi kujekesa zvakajeka manzwiro aya. Kupa mikana yekuita sangano nevamwe, kuita mabasa anozivikanwa zvakadai sekugadzira mapepa kana kushambidza ndiro, kana kuimba pamwe chete nziyo dzavanofarira kunogona kugadzirisa mafungiro uye kuderedza kunzwa kwekusagadzikana uye kusuruvara.
Dzimwe nguva, zvinetso zvakaoma kana manzwiro ekugumburwa kune vanhu vanorarama nehutano hwemarangwana zvinongova mugumisiro wekusawana zvakakwana kuita basa. Kusimuka uye kuenda kunofamba, kupinda muchikwata chemaitiro aerobic, kana kuita mamwe maitiro ekudzidzira kunogona kubatsira kugadzirisa zvinodiwa izvi.
Ziva Zvaunotarisira
Izwi rinowanzozivikanwa re "zivo simba" ndezvechokwadi pano. Kuziva chatinofanira kutarisa apo kufambira mberi kweAlzheimer kunogona kukubatsira kuti unzwisise maitiro uye ucherechere maitiro ayo sechirwere, pane munhu. Izvi zvinogona kupa tsitsi zhinji uye kuderedza kushungurudzika.
Zvisingabatsiri Zvinodhaka zveMagariro ekugogodza
Zvimwe zvisingaiti zvinodhaka zvinotarisa kuongorora kushanda kwemunhu ane chirwere cheAlzheimer. Semuenzaniso, kurovedza muviri -kuwedzera kune zvido zvekusangana uye kuderedza zvimwe zvehutano hwehutano kana hwepfungwa muhutano hwehutano-kune simba rekuvandudza kugona kwevamwe vanhu. Saizvozvowo, kuramba mupfungwa zvakashanda kwakaratidzawo kuti kunobatsira mukuchengetedza chiyeuchidzo uye unyanzvi hwekufunga muhutano hwekuora mwoyo. Kunyange zvazvo nzira idzi dzisingagoni kuporesa chirwere cheAlzheimer, vanogona kunge vachipa rubatsiro rusingabatsiri.
Mishonga Inobatsira uye Inoshandiswa
Sezvo mishonga isingabatsiri pakuchengetedza Alzheimer's, vazhinji vakashandura kune dzimwe nzira uye mazano ekurumbidza . Nhengo dzejeri dzichiri kunze kwezvizhinji zvezvirevo izvi, uye tsvakurudzo iri kuenderera mberi. Vamwe vanhu vakarondedzera kuvandudzwa kwekucherechedza nemishonga yakaita seyakonokonti mafuta , asi tsvakurudzo ichiri kumirira kubudirira kwayo.
Kana iwe uchida kuedza kukurudzira kana mamwe maitiro ekurapa, unofanira kuzvikurukura nechiremba wako, sezvo vamwe vane mikana yekubatana nemimwe mishonga kana kuti zvinogona kukonzera migumisiro yakaremara.
Clinical Trials
Kune dzakawanda zvekuchirapa zvinongoramba zviripo izvo zvakanyatsorongedzwa kuti zviongorore mushonga mutsva weAlzheimer's disease. Mimwe miedzo yakazaruka uye iri kuunganidza vanhu vane Alzheimer's kana kuti mamwe marudzi ehutano hwekuita mukati mavo. Nyaya yakakwana yezvipatara zvinokonzerwa zvinogona kuwanikwa ku clinicaltrials.gov.
Mibvunzo Yokubvunza Chiremba Wako
Kudzidza nezvechirwere cheAlzheimer kunogona kunzwa kunetseka dzimwe nguva. Nokuda kweizvi, kana uchionana nachiremba wako, zvingave zvichibatsira kuva nemibvunzo yakanyorwa pasi musati wasarudzwa. Izvi zvinofanira kusanganisira kubvunza pamusoro pemishonga inotsanangurwa pamusoro apa kuti iwe unofarira kutsvaga, pane kungoedza ivo pachako.
Usanonoka kubvunza chiremba wako pamusoro pezvisarudzo zvakasarudzwa, zvakadai sokuti zvinoramba zvakachengeteka kutya motokari kana kurarama uri wega . Chiremba wako anogona kupa chinangwa chekuongorora kwekugona kwako kuchengetedza zvakachengetedza mabasa aya, pamwe nekukurudzira nzvimbo dzenharaunda dzinogona kukubatsira, zvakadai semasangano ekuchengetedza utano hwepamusha kana mapoka ekutsigira aAlzheimer.
Uyezve, kana uri kurwisana nezviratidzo zvakadai sekukosha kusagadzikana, kuzvidya mwoyo, kana kukanganisa , izvi zvinofanira kuongororwa nechiremba wako. Anogona kunge ari kutarisa kuongorora unyanzvi hwako hwekufunga (kufunga nekuyeuka mano) uye haungabvunzi zvakananga nezvimwe zviratidzo zvekuzvibata uye zvepfungwa zveAlzheimer's . Zvisinei, kuzivikanwa kwakakodzera uye kurapwa kwezviratidzo izvi kunogona kuvandudza hupenyu hwehupenyu muAlzheimer's .
Shoko Rinobva
Kunyange zvazvo pasina chirwere chekare chechirwere cheAlzheimer, chirudzirwe. Vatsvakurudzi vari kushanda nguva dzose pakuwana nzira inoshanda yekurapa uye nzira dzokudzivirira. Zvakawanda zvakadzidzwa pamusoro pekuti mararamiro eAlzheimer anokanganisa sei uropi, uye ruzivo urwu rwakawedzerwa hunoenderera mberi kuti ruve nemafungiro mutsva pakuvandudzwa kwemushonga, kurapa, nekudzivirira.
Zvinonyanya kukosha, usakanganwa kuisa simba rekugara iwe sezvaunotarisana nechirwere ichi. Chirwere cheAlzheimer chirwere apo pane zvinosuruvarisa zviri nyore kuzviparadzanisa isu, asi izvi hazviwanzobatsira. Hatigoni "kugadzirisa" chirwere cheAlzheimer, asi tinogona kupa rubatsiro, ruzivo, nekukurudzira nekubatana pamwe chete.
Sources:
Alzheimer's Association. Mishonga Yekutadza Kuyeuka. > http://www.alz.org/alzheimers_disease_standard_prescriptions.asp.
US National Institutes of Health. National Institute on Aging. "Dambudziko reAlzheimer Medication Fact Sheet." http://www.nia.nih.gov/Alzheimers/Publications/medicationsfs.htm
US National Institutes of Health. National Institute on Aging. "Mishonga Yokurapa AD Zviratidzo uye Maitiro." http://www.nia.nih.gov/Alzheimers/Publications/CaringAD/medical/medicines.htm