Mamiriro Akabatanidzwa neKuwedzerwa Kungozi Kwemwoyo Wezvirwere
Vanhu vanorarama neHIV vanowanzove vakakwidziridza cholesterol uye triglycerides mazinga, izvo zvinokonzerwa kwete chete nehutachiwana pachahwo asi nemishonga chaiyo inoreva kurapa chirwere. Zvimwe zvinhu zvingaitawo kuti zvive nemamiriro ezvinhu aya, anozivikanwa, maererano, maererano hypercholesterolemia uye hypertriglyceridemia .
Cholesterol Chii?
Cholesterol inotsanangurwa neAmerican Heart Association seyakasviba muropa remunhu iro rinobva kune rechiropa chomunhu uye zvimwe zvokudya-kunyanya zvokudya zvitsva uye mazai ezvekaka.
Kuwedzeredza kweklesterolori kunogona kuvhiringidza arteri mumuviri, izvo zvinodzivirira kukwana kweropa kwakakwana kubva pakuwana nhengo dzinokosha, zvinosanganisira moyo neuropi. Izvi zvingaita kuti munhu awedzere njodzi yekurwara nemwoyo kana kurohwa.
Kune marudzi maviri echolesterol:
- LDL cholesterol : inofungidzirwa kuti "yakaipa" cholesterol, yakakwirira LDL inobatanidzwa kune njodzi yakanyanya yekurwisa mwoyo uye kurwara. Chikafu chinopfuma mune mafuta akazara uye anotengesa-senyama yakatsvuka, zvokudya zvakashongedzwa, uye zvinopisa-kubatsira kumutsa LDL cholesterol.
- HDL cholesterol : kazhinji inonzi "yakanaka" cholesterol, pasi peH HDL inobatanidzwa nehuwandu hwekurwadziwa kwepfungwa kana chirwere. Munhu ane chirwere , ane chirwere cheshuga chechirwere cheshuga , kusvuta, uye kuva nemararamiro ehupenyu anotapudza HDL cholesterol mazinga.
Kose cholesterol inoratidzirwa nokuwedzera HDL + LDL + 20% yemunhu we triglyceride level. Kazhinji, chinoda cholesterol yakawanda inenge iri pasi pemamirigiramu 200 ne deciliter (mg / dL).
Chii Chinonzi Triglycerides?
Triglycerides ndiyo inowanikwa mafuta ayo anobva pane zvekudya kana kuti anoumbwa nemuviri kubva pakuparara kwemakhahydrates. Mushure mekunge munhu adya kudya, mamwe maoriki asina kushandiswa pakarepo simba anoshandurwa kuva triglycerides. Izvi zvinowanzofamba kuburikidza neropa kusvikira vasvika kumafuta ane mafuta, kwaanochengeterwa kuti vashandiswe gare gare.
Yakawanda triglyceride mazinga yakabatanidzwa mukana wekuwedzera wekutengesa kweropa uye rudzi rwechipiri chirwere cheshuga. Uyezve, kana munhu ane high triglycerides uye kana yakakwirira yeLDL yepamusoro kana pasi yeHDL, ipapo iye achave ari pangozi yekurwadziwa kwemoyo kana kurohwa.
Nenzira yakawanda, chirwere chinowanzoitwa triglyceride chinorondedzerwa sechiri nemamiriyoni pasi pemamiriyoni 150 ne deciliter (mg / dL), nepo chikwata chakakwirira che triglyceride chinotsanangurwa se 500mg / dL kana kupfuura.
Zvinhu zvinowedzera dambudziko remunhu we hypertriglyceridemia zvinosanganisira:
- Kuwedzera muviri
- Zvisizvo zvisingaiti
- Kunyanyisa kunwa doro
- Sodya fodya
- Zvokudya zvakapfuma mu-carbohydrates (kufanana neshuga zvinotapira, makiki, chingwa uye mbatata)
- Mamwe marapirwo akadai sorudzi rwechipiri rwechirwere cheshuga kana chirwere chisingaperi chepfungwa
- Mimwe mishonga (semishonga antiretrovirals, estrogen uye corticosteroids )
- Munhu ane maitiro ekugadzira
Cholesterol uye Triglycerides uye Vachibatanidza neHIV
Utachiona hunokonzerwa nehutachiona hunoita kuti huwedzere cholesterol uye triglyceride mazinga ari munhu ane utachiona. Izvi zvinogona kuwedzera kuwedzererwa nemunhu weHIV antiretroviral drugs , iyo inogonawo kukanganisa zvakanyanya cholesterol yemunhu.
Zvirwere zveHIV zvinorondedzerwa seprotease inhibitors (PIs) zvinowanzobatanidzwa kune zvose hypertriglyceridemia uye hypercholesterolemia.
Nucleoside reverse transcriptase inhibitor (NRTI) - mapoka madhiragi anogonawo kuita izvi. Pakati pavo:
- Ziagen (abacavir)
- Zerit (stavudine)
- Retrovir (zidovudine, AZT)
- Kaletra (lopinavir + ritonavir)
Kutungamirirwa kweHool Cholesterol uye Triglycerides
Pamusana pekukonzera-uye-kushamwaridzana kusangana pakati peHIV uye yakasimudza cholesterol / triglycerides, vanhu vane HIV vanofanira kuongororwa zvirwere zveropa nguva dzose kuti vaone sarum yavo yeropa.
Upenyu hwekuchinja (kusanganisira kurovedza muviri , kudya kwakaderedzwa-mafuta uye kuguma kusvuta ) kunogona kuderedza zvakawanda zvekukanganisa kwehutano uye hutachiona. Muzviitiko zvizhinji, kushandiswa kwemishonga yemagetsi nemamwe mishonga kuderedza cholesterol uye triglycerides zvinogona kukurudzirwa kana maitiro akangobva pane izvo zvingaonekwa seine utano, kunyanya kune vanhu vakwegura kana avo vane zvirwere zvemagetsi.
Tsvakurudzo kubva kuKaiser Permanente Division of Research yakaratidza kuti mishonga yeCholesterol inogona kushanda zvakanaka pakati pevamwe vanhu vane HIV vane mungozi yehutano hwehutano. Kunyange zvazvo njodzi yezvirwere iri yakakwirira nekuda kwechirwere chisina kuitika chinogona kuitika nemamwe ma antiretroviral, mishonga inopesana nehushutori inoratidzika kushanda zvakanaka kwazvo kutonga zvakakwirira kana kuti zvinotyisa.
Mukuwedzera kune tsika yemasikirwo emitemo, kushandiswa kwemapurisa anotungamirira mashandisi akadai seLolid (gemfibrozil) ave akaratidzwa kuti zviri nani kudzora zvose zvekulesterol uye triglyceride mazinga kune vanhu vanorarama neHIV.
Sources:
AIDSInfo. "Migumisiro Yechirwere yeHIV Mishonga." Dhipatimendi reUnited Health Health and Human Services (DHHS); yakasvika musi waSeptember 25, 2015.
American Heart Association (AHA). "NezveKolesterol." Dallas, Texas; yakasvika musi waSeptember 25, 2015.
Feeney, E. uye Mallon, P. "HIV neHART-Associated Dyslipidemia." Vhura Cardiovasc Med J. 2011; 5: 49-63.
Kaiser Permanente. "Chidzidzo Chapamusoro Chikuru Chinoenzanisa Kushandiswa kweCholesterol MuHIV Varwere Uye Varwere Vasina HIV." SayenziDaily . Yakabudiswa March 2, 2009.