Zvikonzero nei Kanzerano Inodzokera shure Kwemakore Ekuregererwa
Pasinei nokurapa kwakadai sokuvhiya , chemotherapy , uye remishonga yehutachiona , kazhinji kenza inodzoka. Uye kunyange zvazvo zvirwere zvakawanda zvekenza zvinodzoka mumakore mashanu okutanga, vazhinji vedu tinoziva nezveumwe munhu akagara nekenza pasina makore uye kunyange makumi emakore vasati vadzokera kenza. Nei vamwe vana kancza vachidzoka, uye izvi zvinoitika sei?
Kukosha kwekuziva Chikonzero cheK Cancers Chidzoka
Pakukumbira kuti sei kanzura inodzoka, tiri kukumbira imwe yemibvunzo inokosha pane incology nhasi.
Kazhinji kadzokazve, kwakadai sekenza yemazamu, inoshandiswa. Mukenza wekutanga uyo waiva danho 1 kana shanho 2 ikozvino nhanho 4 kana metastatic. Sezvo vanopfuura 90 muzana yekenza yekufa kunoitika nekuda kwemasimisita, ichi mubvunzo unokosha.
Zvakawanda zvekurapa kwatinoshandisa kwekenza ndeyokudzivirira kenza dzemasero kubva pakuramba uye "kuwana mukana wokuviga." Ichi ndicho chikonzero che "adjuvant chemotherapy" yakapiwa makondombera emvere uye mapapu okutanga, sezvo chemotherapy inorapwa zvirongwa zvakagadzirirwa kurwisa masero aya anoshaya. Asi pane chimwe chikonzero, kakawanda, masero akasiyiwa kumashure. Kunyange pavanoramba, zvakadaro, vanogara kupi? Nemhaka yei mamwe masero emukenza asingaonekwi kuita chinhu kwemakore makumi maviri uye achikura zvakare? Ngatitarise mamwe emibvunzo iyi, asi kutanga inobatsira kutsanangura izwi rekuti tichashandisa.
Brief Review of Cancer Terminology
Kana uchitaura nezvekenza inodzoka zvakare inobatsira kutsanangura chaizvoizvo kudzokorora, uyewo mamwe mazita mashomanana.
- Kudzokorora . Kenza kudzokorora kunoreva kenza inodzoka (inodzoka, inodzoka zvakare, kana kuti inodzoka) mushure mekunge nguva yechirwere yakange yave kuregererwa (kazhinji zvinoreva kuti hapana humwe uchapupu hwehosha (NED) uye kenza haina kuonekwa pa zvikwangwani.) Kunyange zvazvo pasina humwe tsanangudzo yakajeka yenguva iyo inofanira kupfuura apo mumwe munhu ane kenza yakasununguka uye kana kenza inonzi inodzokororwa, vazhinji veoncologists vanodavira kuti kanzira inodzoka mumwedzi mitatu inofambira mberi pane kufambira mberi.
- Kufambira Mberi (Kuwedzera Kwirwere - PD) . Kubudirira kwekenza kunoreva kuve nekenza iri kuwedzera uye yakawedzera zvishoma makumi maviri kubva muzana muhukuru kana kupararira mushure mekurapa.
- Kusarudzwa Kwezvakaitwa - Kushanda kwechikamu chekurapa kunoreva kuti chirwere chinoderera zvishoma ne30 muzana muhukuru, asi hachibvi zvachose sezvinoratidzwa pamakiriniki ekuongorora kana kuongorora. Izvi zvinonziwo kuderedza kusarura.
- Dhaka Dzaase . Dambudziko rakasimba, iro rinonziwo static disease, rinoreva kuti chirwere hachikure kana kuti chichireruka zvikuru. Icho chinoreva zvakare kuti hapana mavumbi matsva uye kuti chironda chacho hachina kupararira kune dzimwe nzvimbo itsva dzomuviri. Dumbu racho harina kuwedzera zvakakwana kunzi chirwere chinopfuurira (20 peresenti inowedzera kana kupfuura) kana kuti yakaderera zvakakwana kunzi kusarura zvishoma (zvinenge 30 muzana inoderera.)
- Complete Response . Kunyatsopindura kana kupera kwakakwana kunoreva chinhu chimwe chete sekuregererwa kwakakwana kana NED (pasina uchapupu hwehosha) Izvi zvinoreva kuti hapana chirwere chinoramba chiripo chinogona kuonekwa pakuongorora mumuviri, uye kuongorora, kana kuongorora ropa, asi hazvireve kuti kenza ndeye akapora.
- Kuregererwa . Kuregererwa hazvirevi kuti kenza inoporesa, asi pane zvinoreva kusavapo kwezvirwere. Kune marudzi maviri ekuregererwa. Mukukanganwa kwakakwana , kenza haikwanise kuonekwa kuburikidza nekuongorora kwepanyama kana kuburikidza nekuongorora kwehutachiona. Mukuregererwa kwakasarura , kenza ichiri kuonekwa asi yakaderera muhukuru.
- Hapana Uchapupu Hwezvirwere (NED) . NED inotsanangurwa nenzira imwecheteyo sekuregererwa kwakakwana - kenza haigone kuonekwa nemuedzo chero upi zvawo kana kuongorora.
- Kudzoka - Izwi rinodzokorora rinowanzoshandiswa zvakasiyana nekudzokorora.
Nei Vamwe Kanzera Inodzoka?
Sezvo kudzokorora kunokonzera kukanganisa (kurwara) uye kufa (rufu) kubva kune kenza, kunzwisisa kuti sei kanzira inodzoka inokosha pakuvandudza mararamiro evanhu vanorwara nekenza. Zvinotarisirwa kuti, sezvo ruzivo ruchivandudzwa munharaunda ino, kuwedzera kwehuwandu hwevanhu vazhinji vanodarika kanzera kuchawedzera.
Zvakakosha kutanga nokutaura kuti zvinotora masero mashoma emukenza akasiyiwa mushure mekurapa kwekenza iyo kudzoka.
Zvinotora mamiriyoni akawanda emasero ekenza pamwe chete kuti aite tumarara inogona kuonekwa pamwe nemasikirwo akafambisa ekufungidzira.
Zvakadini Nekuvhiya Uye Kurapa Kwokurapa Kwinoita Sekubudirira?
Kana iwe ukavhiyiwa nemaranzi akajeka pamushumo wehutano hwako, uye kana scan isina uchapupu hwekenza, zvingava zvakaoma kunzwisisa kuti nei kenza ingadzoka. Asi kunyange kana pasina masero anokonzera kuonekwa pamiganhu yemarara, mamwe masero anouraya angangodaro akapararira kuburikidza ne lymphatic system, munzvimbo ino kusvika kumatekisi, kana kuti neropa kusvika kune dzimwe nzvimbo dzomuviri. Aya masero emukenza asingagoni kuonekwa anonzi ma micrometastases .
Kuvhiya ose uye remishonga inonzi radiation inonzi "mishonga yemunharaunda." Sezvo vakadaro havatapuki nekenza yemasera ayo akafamba kupfuura nzvimbo yekurapa. Mukuwedzera, therapy inonzi radiation haigoni kuuraya ose masero emukenza. Radiation inoshanda neDNA inokuvadza mumasero maviri ekenza uye masero akajairika. Kungofanana nemasero matsva angangodzokorora miviri inotevera, mamwe masero emukenza anogona "kupora" zvakare. Kubvira kwe micrometastases ndiyo chikonzero chekuti vamwe vanhu vanogamuchira chemotherapy adjuvant ----------------------- chemotherapy iyo inopiwa mushure mokupedzwa kwekurapa kwaro nekuvhiyiwa kana radiotherapy kuvimbisa kuti micrometastases inopedzwa.
Sei Kachiedza Kemotherapi Kuurayisa Mamwe Makero Ekanano?
Chemotherapy, zvakasiyana nekuvhiyiwa uye remishonga yehutachiona, inofungidzirwa sehutachiona hwehutachiona, hwakagadzirirwa kusabata kwete masero ekenza chete pedyo nechirwere asi kubvisa kenza dzemasera dzakapararira kupfuura nharaunda dzomuviri dzinobatwa nekuvhiyiwa uye kupiswa kwemhepo. Saka nei chimiro chemakemikari isingagoni kuuraya masero emukenza mumuviri? Kuti unzwisise mhinduro kumubvunzo uyu, zvakakosha kunzwisisa zvishoma nezvekuti chemotherapy inoshanda sei. Kazhinji chemotherapi yemishonga inoshanda pane imwe nguva mukugadzirisa kushandiswa kwesero. Haasi ose masero emukenza ari kugovera nguva dzose, uye masero asina kuparadzanisa, kana ari pane imwe nzvimbo yakasiyana mumasero ekuparadzanisa apo mamwe makemikari emishonga anotarisa, anogona kupona. Ichi ndicho chikonzero chekuti vanhu vanowanzobatwa nevanopfuura imwe chemotherapy drug (chemotherapy drugs inoshanda pamatunhu akasiyana mumasero ekuparadzanisa masero) uye nei chiropotherapy inowanzopiwa muzvikamu zvakasiyana zvakaparadzana kupfuura nguva.
Makero Ekanatani Anogona Kuvanza Kwemakore Here Kana Kuti Makumi Makumi?
Kune mazano mashomanana akave akarongerwa kubhadhara kune izvo zvinoita seine kenza yemukirini yekwanisi ye "kuviga" kwenguva yakareba. Somuenzaniso, 20 kusvika ku 45 muzana yeestrogen-receptor yakanaka yekenza yepabonde yekudzoka inoitika makore kana makumi emakore mushure mekunge kenza yakabudirira kurapwa.
Imwe iyi ndiyo pfungwa yekenza stem masero , chikamu chekenza masero . Zviri nyore , iwe unogona kufunga nezvekenza masero seine hurumende. Muchiitiko ichi, kenza yemasero emasero angadai ari "mukuru" uye ane simba kupfuura mamwe masero emukenza (akawanda asingagadzirwi kurapwa saikhemotherapy, zvichida nokuti vanoparadzanisa zvishoma nezvishoma kudarika maitiro emukenza.) Kunyange kurapwa kwekenza kunogona kuuraya vazhinji vevarwi , idzi idzi dzepamusoro dzakasarudzwa dzikaramba dzichirarama, dzakagadzirira kukura zvakare.
Imwe pfungwa ndeyeye dormancy . Nokuda kwechimwe chikonzero, kenza yesero (yakaoma masero inogona kuva nekenza shem cells) inogona kurara (semiti munguva yechando, kana foreal spore) uye, kana iine mamiriro akanaka, inotanga kukura zvakare. Iwaya ane hosha dzemasero emukenza anogona "kurara" kwemazuva mazhinji kwenguva refu asati "kumuka" uye kupinda mukukura nokukurumidza. Vanogona "kuenda kunorara" nekuda kwechirongwa chemasimba ehurumende, kana kusava kweangiogenesis (kukwanisa kwekenza kuita mitsipa yeropa kuidya uye kubvumira kuti ikure) uye "kumuka" kana maitiro ezvirwere zvemuviri asina kushanda zvakanaka ( immunosuppression ) kana angiogenesis ichiitika.
Chii Chinonzi Cancers Haingazodzokeri (Recur) uye Inogona Kufunga Sechirapa?
Vanachiremba havawanzoshandise shoko rokuti "kurapwa" nokuti vazhinji vese vane mvumo yekudzoka. Kusiyanisa kunosanganisira mamwe matanho ekutanga emakirini ane ngozi shoma yekudzoka (somuenzaniso kanangwana kenza yekenza).
Iro Kanza Inoita Kuti Iwedzere Kurwisana Here?
Mimwe mishonga inogona kunge yakanyanyisa kurwisa kana ichidzoka, uye nokuda kwemamota akawanda atinofanira kufunga kuti mushonga wekutanga unoshandiswa unowanzoonekwa sewo unonyanya kushanda. Asi izvi hazvisi nguva dzose. Dzimwe mhando dzekenza dzinogona kuraswa kunyange mushure mokunge dzichidzoka, somuenzaniso, kenza yemukenza .
> Sources:
> Almog, N. Mamiriro matsvene anokonzera tumor dormancy. Cancer Tsamba . 2010. 294 (2): 139-46.
> Kleffel, S., uye T. Schatton. Tumor dormancy uye kenza stem masero: mapande maviri emari imwe chete? . Kufambira Mberi Mukuongorora Mishonga uye Biology . 2013. 734: 145-79.
> Li, S., et al. Muenzaniso weMambure Dormancy / Kudzokorora mushure meKfupi kwenguva refu Chemotherapy. PLOS Rimwe . Yakabudiswa May 20, 2014.
> National Cancer Institute. Kana Kansa Inodzoka.
> Wang, Sih-han, naShiaw-Yih Lin. Tumor dormancy: inogona kurapa chinangwa chemuviri mukurara nekudzoka kwemasiteri. Ongororo Hematology uye Oncology . 2013. 2:29.