Kusiyanisa Pakati pePIsIs uye H2 Zvidziviriro zveKutsamwa

by Sharon Gillson; Yakadzokororwa naEmymy Ludwig, MD

Kuenzanisa Mhando mbiri dzeMishonga yeMishonga yeGERD

Kana uine kuora mwoyo, zvichida unoshamisika pamusoro pemusiyano pakati pemishonga inoshandiswa kurapa: proton pump inhibitors (PPIs) uye H2 blockers. Zvose zvinodzvinyirira gastric acid secretion. Ivo vakasiyana, zvisinei, kuti vanoita sei izvi.

Apo maPPIs akavhara mapurusi emaprotoni mudumbu, H2 blockers inoshanda nekuvhara histamine receptors mumasero anobudisa-asidi mudumbu.

Dzidza zvakawanda pamusoro pekusiyana, kuti vanogona sei kubetsera kuora mwoyo kwako, uye nei chiremba wako achikurudzira mumwe pamusoro peumwe.

Chii Chinokonzera Kuora Kwemvura uye Chii Chinodiwa Kuchibata?

Kushungurudza kunogona kukonzerwa nechiitiko chinowedzera chinonzi gastroesophageal reflux disease (GERD) . GERD inowanikwa apo asidi kubva mudumbu inodzokera kumusango. Kazhinji musimba weAidhi uye zvimwe zviri mukati zvinochengetwa mudumbu (uye kunze kwegomba) nevhavha inonzi low esophageal sphincter (LES). Asi zvinhu zvakawanda zvinogona kuderedza iyo valve kusanganisira:

Kudya zvokudya izvo zvinowanzokonzera kuora mwoyo , zvakadai sezvokudya zvechidimbu (semuenzaniso, tomate nemichero yezereru), zvokudya zvinonaka, kana chokoti
Kunwa doro kana caffeine
Kusvuta fodya
Kuva nezvimwe zvirwere, zvakadai seshuga nechirwere
Kuva nekuwedzera kumanikidzwa pamimba yako (somuenzaniso, kuneta, kuberekwa, kana kusungirirwa kwechiuno)

Upenyu huri kuchinja - kurega kusvuta, kubvisa doro uye zvokudya zvinokonzera kuora mwoyo, uye kurasikirwa - ndiyo inowanzova mutsara wokurapa kunetseka.

Asi dzimwe nguva mishonga inokosha, uye iyo ndiyo iyo PPIs neH2 blockers inogona kubatsira.

Proton Pump Inhibitors (PPIs)

Iproton pump iyo inomukemu mune mamwe masero emudumbu. Iyo "mapumpu" acid mukati mudumbu. Zvinotora i-non-acidic potassium ion kubva mudumbu uye inoiisa iyo ne acidic hydrogen ion.

Iyi hydrogen ion ndiyo inoita kuti zvinhu zviitike. Nokuisa ioni yakawanda yakawanda mudumbu mako, iyo pombi inoita kuti zviri mukati momuviri wako zvive zvakanyanya. Asi nekumisa chiito chepombi (kuvhiringidza), kuvhara asidi mukati mudumbu kunomiswa.

Proton pump inhibitors inoshandiswa kurapa GERD, dumbu uye duodenal ulcers , erosive esophagitis uye Zollinger-Ellison syndrome . PPIs inogona kushandiswa iri woga kana kutorwa pamwe chete nevan antacids. Zvose maPIsIs akafanana maitiro avanoita, uye hapana humwe humwe humwe hunoratidza kuti mumwe anoshanda kupfuura imwe. Zvisinei, dzakasiyana nenzira iyo dzinoputsika neropa uye kuti dzinopindirana sei nemimwe mishonga. Uyezve, migumisiro yevamwe maPPI inogona kuramba yakareba kupfuura vamwe uye inogona kutorwa zvishoma.

PPIs inosanganisira:

Aciphex (rabeprazole)
Nexium (esomeprazole)
Prevacid (lansoprazole)
Prilosec (omeprazole) : inowanikawo kune-over-the-counter sePolosec OTC
Protonix (pantoprazole)
Dexilant (Dexlansoprazole)

PPIs inotanga kunonoka kwechiito apo H2 blockers inotanga kushanda mukati meawa. PPIs inoshanda kwenguva yakareba: yakawanda kusvika maawa makumi maviri nemana, uye migumisiro inogona kupedza kusvika mazuva matatu. H2 vachengeti, zvisinei, kazhinji vanoshanda chete kusvika maawa gumi nemaviri.

H2 Blockers

Mishonga yeparietal mudumbu yako yakagadzirirwa inokurudzirwa nenzira dzakawanda dzekubudisa asidi.

Chimwe chezvinhu izvi zvinokonzera asidi ndeye histamine, iyo inosungira ku histamine 2 receptors pane parietal cell. H2 vachengeti, vechokwadi kune zita ravo, vadzivisa nzvimbo idzi dzekugamuchira uye saka kuderedza kushandiswa kwemasiti.

H2 blockers dzinosanganisira:

Ko H2 Blockers Inosiyana Sei naProton Pump Inhibitors (PPIs)?

Kunyange zvazvo vaviri H2 blockers uye proton pump inhibitors zvose zvinodzvinyirira gastric acid secretion, kune nzira dzakawanda iyo mishonga iyi yakasiyana:

Maitiro avanoita: Vanoshanda pamatanho akasiyana mukugadzirwa kwemuviri acid. H2-blockers (histamine blockers) chivharo chechimwe chekutanga chekugadzira asidi. Proton pump inhibitors inodzivirira danho rekupedzisira mumugwagwa wekuvhara asidi mudumbu. Mune mamwe mazwi, asidi yakagadzirwa (iyo inogona kuderedzwa nekuda kweH2 blocker) inodziviswa kusvika mudumbu.

Kwavanoita: Mishonga iyi yose inoshanda mumapareetal masero, ayo ari mashizha anobudisa asiri mumucheka wemudumbu. H2 vachengeti vanoshanda nekuvhara histamine receptors mu parietal masero kuti vaderedze kuwanda kwemashizha anobudiswa (kunyange pane zvimwe zvinokonzera kuitira kuti mamwe asiri achiri kubudiswa). Proton pump inhibitors inoshanda nokuvhara mapuroni emaprotoni mumasero aya uye kudzivirira kuti asidi isingavigwa mumimba.
Zvakanyatsoshanda sei: Proton pump inhibitors inokonzerwa nekudarika kukuru kweAsiri kune H2 blockers. Izvi ndezvokuti pane zvimwe zvinokanganisa, kuwedzera kune histamine 2, iyo inokurudzira kugadzirwa kweAsiri neH2 blockers kungovhara histamine 2.
Vanokurumidza kushanda sei: H2 blockers vane kutanga kwekuita kwekuita, vachiwanzoshanda mukati renguva yekutora mishonga. Proton pump inhibitors, nenzira yakasiyana, vane nguva yakanonoka kuita.
Inguva yakareba zvakadini: H2 blockers inogona kushanda kwemaawa 12 mushure mekutora mishonga. Proton pump inhibitors inotora nguva refu. Mamwe maPPI anogara kusvika maawa makumi maviri nemaviri, asi mamwe angava nemigumisiro inoguma kusvika mazuva matatu.
Zvikanganiso: Pamusana pezvirongwa zvakasiyana-siyana zvekuita, migumisiro yemigumisiro yezvikamu zviviri zvemishonga inopesana zvakare, kunyange zvazvo mhando mbiri dzemishonga inowanzochengetedzwa zvakanaka. Mikana inogona kuitika inogonawo kusiyanisa pakati pemishonga chaiyo munharaunda imwe neimwe. NeH2 blockers, misoro inowanikwa. Proton pump inhibitors inowanzochengeteka zvikuru asi inosanganiswa (mune zvimwe zvidzidzo asi kwete zvose) nehuwandu hwehuputi hwechiuno . Pane zvimwe zvinogona kuitika, uye zvakakosha kukurukura izvi nechiremba wako usati washandisa chero ipi yemishonga iyi.

Ndezvipi Zvimwe Ndezvipi H2 Zvidziviriro uye maPIs Anoshandiswa Kurapa?

Zvakanaka kuziva kuti kuwedzera pamwoyo (uye kunyanya, GERD), mishonga iyi inoshandiswa kurapa esophagitis uye kuderedza zviratidzo zvepptic ulcer chirwere . Zvinogonawo kushandiswa kurapa zvimwe zvirwere zvekudya zvinogona kukonzera kudarika muviri mudumbu.

Kusarudza Pakati peH2 Blockers uye Proton Pump Inhibitors

Unogona kushamisika kuti nei chiremba wako achisarudza imwe yemishonga iyi pane imwe. Sezvo proton pump inhibitors inopa huwandu hwekugadzirisa asidi, izvi zvinowanzodiwa kuti zviratidzo zvive zvakanyanya.

Nguva yekutanga kwechiito ingasarudzawo kuti ndeupi mushonga wako chiremba achakurudzira. Kubvira sezvo H2 blockers inoshanda nokukurumidza, inowanzoshandiswa kana munhu ane chirwere chezviratidzo. Nokuda kwechiito ichi chinokurumidza, mishonga iyi inogona kushandiswa kune avo vanongogara vachinge vakagumbuka.

Sezvo proton pump inhibitors inotora nguva refu kuti itange kushanda asi ine simba guru, iyo inowanzoshandiswa kune avo vane zvirwere zvisingaperi zvekushaya mwoyo kuti vawane simba pamusoro pezviratidzo.

Kana iwe uchangobva kuongororwa neGERD, taura nachiremba wako nezverongwa hwekurapa. Kana iwe usingagoni kuwana zororo nemararamiro ehupenyu, kuedza kwemavhiki masere kwePARI chirongwa zvingave zvichikurudzirwa.

Kana iwe uchiramba uine zviratidzo mushure mekupika kwePPI kuregererwa kana kana uine zvinetso kubva kune GERD yako (seyakasangana neesophagitis), kugadzirisa (kwenguva yakareba-nguva) PPI remishonga inogona kusarudzwa. Dzimwe nguva H2-blocker, panzvimbo pePPI, inokurudzirwa kugadzirisa chirwere.

Prescription vs. Over-the-Counter Mushonga Wekushaya Mwoyo

Mishonga yemishonga inoshandiswa kuora mwoyo inowanika seyese mishonga uye semishonga inopfuura-the-counter. Kunyange zvazvo mishonga iyi yakafanana, mishonga-in-counter inowanika pamutengo wakaderera (kazhinji chikamu chehafu yemirayiro yepamutemo).

Taura nachiremba wako kana wemishonga usati watora chimwe cheizvi kune mumwe. Uyewo, cherechedza zvinogona kuitika migumisiro yemasikirasi. Zvinogona kuderedza kushandiswa kwemamwe mishonga, kusanganisira mamwe mishonga yemwoyo.

Mimwe Mishonga Inoparadza Mwoyo

Mukuwedzera kune H2 blockers uye proton pump inhibitors, vanhu vazhinji vanoshandisa antiacids kuti vabatsire kudzora kuora mwoyo kwavo. Ramba uchiyeuka kuti kune kusiyana kwepakati pevarume vese uye taura nachiremba wako nezvepi yemishonga iyi ingakunakira iwe. Mukuwedzera kune mishonga uye mararamiro ehupenyu, vamwe vanhu vanoda kurapwazve, zvakadai sekuvhiyiwa kwechirwere chinonzi hiatal .

Kunze kweMishonga Yekushungurudza

Neine mishonga yose iripo yekurapa kuora mwoyo, tinowanzokanganwa nezvemararamiro emararamiro anokwanisa kubatsira kuora mwoyo . Kana iwe uchida mishonga kuti itarise kuora mwoyo kwako, iva nechokwadi chekuona kana chimwe chezviyero izvi chinogona kuvandudza zviratidzo zvako:

Rega kusvuta. Kusvuta fodya kunokonzera kuora mwoyo nenzira dzinoverengeka.
Funga nezvekudya kwako. Iva neruzivo nezvezvokudya izvo zvinokonzera kupisa mwoyo, pamwe nekudya izvo zvakanyatsorambidzwa kune vanhu vane kuora mwoyo .
Deredza doro rako. Kunwa kunogona kukonzera kuchema kune vamwe vanhu.

Shoko Rinobva

Kana uine mibvunzo pamusoro pemishonga yako yekushaya mwoyo, tapota taura nechiremba wako. Zvakakoshawo kutora mishonga yako sezvinorayirwa, kusanganisira kuomerera kune imwe nguva yakakodzera uye nguva yekudya. Pamwe nemishonga, tarisa nzira dzaungaita nayo mararamiro ehupenyu hunochinja huchaitawo kuti usanyanya kuora mwoyo.

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