Kunzwisisa Mafungiro Ako NeHodgkin Disease
Kana iwe kana munhu waunoda ari kurarama neHodgkin lymphoma , zvichida wakambozvibvunza nezvehupenyu hwehutachiwana hwechirwere. Hodgkin lymphoma kazhinji inobata vechidiki munguva dzezvibereko zvinowedzera muupenyu hwavo. Pakati pekuita mabasa uye sevabereki vevana vaduku, vanhu vazhinji vane chirwere vane mibvunzo pamusoro pe "tarisiro" yeupenyu huri kutarisira.
Zvinofadza, chirwere cheHodgkin (zita rekare rekenza iyi) nderimwe remhando dzakanyanya kurapwa dzekenza.
Panguva imwechete iyo iwe unogona kunge wakakurudzirwa nekunzwa kuponeswa kwehutano neHodgkin lymphoma, zviri nyore kusava nehanya pakunzwa zvakare imwe musoro musoro unoparidza "kufambira mberi" mukurapa. Mashoko akanaka ndeokuti-maererano neHodgkin chero zvakadaro-izvi hazvirevi kungofanana kana tariro yechema. Tichazotaura pamusoro pekuti kutarisira hupenyu kwakagadziridzwa sei munguva yakaitika kare, uye zvipi zvehutano zvakagadzira kusiyana.
Zvimwe zvekuvhiringidzika pavanenge vachitaura nezvekurarama nekenza dzine chokuita neropa zvakadai seHodgkin lymphoma inobva kune izvo vanhu vanoziva nezvimwe zvirwere, zvakadai sekenza yemazamu. Vanhu vanowanzoziva kuti kenza yemazamu inogona sei kudzokorora makore kana makumi emakore mushure mekurapa. NeHodgkin lymphoma, kakawanda kudzoka kunowira kare, uye izvi zvinonokazve kudzoka hazvishamisi. Mune mamwe mazwi, avo vakapona makore mashanu neHodgkin lymphoma vanogona kunge vari vapenyu venguva yakareba kudarika vanhu vane zvirwere zvakasimba.
Ngatitaurire nezvemazuva ano ehupenyu huwandu neHodgkin lymphoma, zvinhu zvinogona kukanganisa upenyu hunotarisirwa kubva pachigamba kusvika kumakore pakuongororwa, uye chii chaunogona kuita iwe pachako kuti uwedzere kufambisa kwako.
Hodgkin Lymphoma: Kukurukurwa Pfupi
Hodgkin lymphoma ikenza ye lymphatic system , chikamu chemuviri wesimba .
Inowanzoitika kune vechidiki vechidiki vane miviri miviri inowanikwa; imwe pakati pemakore 15 ne35 uye mumwe kune vanhu vanopfuura makore 55. Hodgkin chirwere chinowanzotanga nekuwedzera kusina kurwadziwa kwemaitiro emumuviri chero upi muviri, asi kazhinji mumutsipa. Ikoko kune marudzi mashanu akasiyana eHodgkin lymphoma iyo yakasiyana pane dzimwe nguva, chikamu chemuviri chavanopinda, uye kuti vanoita sei mukurapa.
Nhoroondo yezvakaitika kare pamusoro pezvakaitika zveHodgkin Lymphoma
Hodgkin lymphoma ndechimwe che "kanorapwa" kanzira, asi izvi hazvisi nguva dzose. Chokutanga chakazivikanwa muzana remakore rechi19, kufungidzira kusvikira pakati pezana remakore rakapera rakanga risina urombo, uye makore mashanu ekupukunyuka ari kuora mwoyo 10 muzana.
Nekuuya kwe-radiotherapy, uye pamwe nekusanganiswa chemotherapy muma1960, kufungidzira kwechirwere ichi kwakagadzirisa zvinoshamisa, uye inenge husiku humwe inenge hafu yevanhu vakaonekwa kuti vakanga vachararama nechirwere ichi.
Asi kunatsiridza mukurapa kunopfuurira. Kubva pane imwe nyaya yakabudiswa neNational Cancer Institute muna April muna 2017, makore mashanu ekupona kweHodgkin lymphoma (mapoka ose akabatana) aiva 69.9 muzana muna 1975 uye 85.4 muzana muna 2009. Zvizhinji zvekuwedzera uku kwakaitika nekuda kwekufambira mberi mune chemotherapy (yakadai saAbVD chemotherapy , uye BEACOPP chemotherapy regimen ), therapy rayation, uye stem cell therapy .
Kuponeswa kwehupenyu kunoramba kuchivandudza, uye kunyange zvazvo mitero yakanyanya kuderera kune avo vanoongororwa pazera remakore ekare kana kuti vane zvikamu zvepamusoro zvechirwere, izvi zvino zviri kuwedzera zvakare. Kushandiswa kwepamusoro-dose salvage chemotherapy uye stem cell transplantation kune avo vanonzwazve kudzoka zvakaramba zvichivandudza kupona. Kushandiswa kwechirwere chinorapwa ne monoclonal antibodies , immunotherapy ne checkpoint inhibitors , uye kusagadziriswa kwemasimusi echistemen cell stplants inopa dzimwe nzira dzokurapa inotarisirwa kuwedzera kuwedzera kupona kune avo vane zvakaoma kubata Hodgkin lymphomas.
Kugadzirisa kwakanakisisa kwezvinetso, zvakadai sezvirwere zvakabatana nekemotherapy-induced neutropenia (pasi shoma rekuyera ropa count), uye iri kuitawo musiyano.
Kuponeswa haisi iyo chete inobatsira yehutano hwakanaka. Pashoma chemotherapy ine chepfu uye remuduku remishonga yemahara yakave iri kuderedza migumisiro yechirwere chekurapa uye, inotarisirwa, iyo yakareba migumisiro yechirwere.
Kuponeswa Nevana Cancers Inoenderana neRopa vs. Mishonga Yakasimba
Kune avo vanonyanya kuzivikanwa nekenza yekenza, zvinobatsira kutora nguva uye kutaura pamusoro pekuti matanho akareba sei (danho III kana gango re IV) reHodgkin chirwere (uye mamwe marariya anokonzerwa neropa) akasiyana nehuwandu kupfuura zvikamu zvepamusoro zvezhinji dzakaoma tumor (zvakadai sekenza yemukomana kana pancreatic cancer).
Matanho anokonzerwa neropa ane chokuita neropa, akadai sechitsauko IV Hodgkin chirwere, anowanzopora. Kusiyana neizvi, zvikwata zvepamusoro zvakasimba zvepamuviri (zvakadai sechitsauko IV chepachifu chepachifu kana chirwere chepakati chechina pancreatic kanzera) hachisi kupora. Saizvozvowo, kufungidzira kwekudzoka zvakare kweHodgkin lymphoma zvakare kwakanakisisa kudarika kudzokorora kwemakumbo akawanda akaoma.
Kunzwisisa Kununura Mahara uye Upenyu Hwakatarisira Kutarirwa
Tichasvika kumanani uye nhamba dzinotsanangura kupona munguva pfupi asi dzinoda kutsanangura kuti zvinorevei izvi zvinorehwa, uye zvimwe zvisingakwanisi kuwanikwa mumatare aya.
Kupona mazinga inowanzotsanangurwa se peresiti inoteverwa neimwe nguva yenguva. Somuenzaniso, unogona kuona 1-makore, makore mashanu, kana makore gumi ekupona. Kana chirwere chine makore mashanu ekupona kunoreva kuti 50 kubva muzana yevanhu vane chirwere ichi vachave vapenyu makore mashanu mushure mekuongororwa.
Dzimwe nguva iwe unogona kuona izwi rokuti " kuponeswa kwemazuva mashoma ." Chirwere chekuchengetedzwa kwemuviri chinoteverwa nehuwandu hwenguva uye chinomirira nguva inotevera apo 50 muzana yevanhu vangadai vafa uye 50 muzana yevanhu vachiri vapenyu. Semuenzaniso, kuponeswa kwemuviri kwemwedzi gumi nematanhatu inguva yakazotevera apo 50 muzana yevanhu vakafa uye 50 muzana vachiri vapenyu. Uine zvirwere zvakadai seHodgkin chirwere, iwe uchaona kuponeswa kwehuwandu kakawanda, asi, nekenza sepancreatic kana kenza yemapapu, kupona kwemajeri kunowanzoshandiswa.
Mukucherechedza mahedheni aya, iyo inonyanya kukosha yekuita ndeyokuti ivo "zvikamu" uye "nhamba." Vanhu chaivo havasi nhamba. Nhamba idzi dzinotsanangura kuti munhu ane nguva ipi neipi yepakati chechirwere cheHodgkin nezvimwe zvinhu zvinotarisirwa kurarama. Asi, kunyange kana kuponeswa kwevanhu kuchiputswa nezera uye shato, hazvibviri kufanotaura kuti munhu mumwe nomumwe achaitei nehosha yacho. Vamwe vanhu vanoita zvakanakisisa kupfuura "chiyero" uye vamwe vanhu havaiti.
Kukanganisa Kwekupona Mari
Sezvakataurwa pamusoro apa, chimwe chezvipingamupinyi zvakanyanya zvekupona kwehuwandu ndeyekuti vanopa mavhareji ehuwandu hwehupenyu, asi hapana munhu anoyera. Mukuwedzera, mararamiro ekupona angave ari kutsausa kune zvimwe zvikonzero.
Kutarisa kumakore mashanu ekupona kwemazana zvinoreva kuti tiri kutarisa kune vanhu vakaonekwa kuti vanenge makore mashanu akapfuura. Munguva iyoyo, mushonga mutsva wakambogadzirwa. Pakupedzisira, mararamiro ekupona anogona kukuudza kuti munhu akaenzana akaitei munguva yakapfuura mushure mekurapwa nemishonga inogona kana kusingashandiswi kunyange nhasi. Nekufambira mberi kunoitwa mukurapa kwekenza, kuponeswa kwehutano kunenge kusina kunyatsokwana sekuenzanisa munguva yakapfuura. Kunyange zvazvo izvi zvingaita kuti zvirevo zvive zvakaoma, zvinotitaurira kuti kufambira mberi kuri kuitwa.
Kurarama kwenguva yakareba kunotova kwakaoma kufanotaura. Dzidzo dzakawanda dzinosiyanisa kufa nekuda kwehutachiona hweHodgkin nekufa nekuda kwezvimwe zvinokonzera, asi zviyero izvi hazvirevi nguva dzose nezvehutano husingaenderani asi nekuda kwekurapa, sakare sekenza.
Kuwedzera kweVanhu Vakapukunyuka Mahara uye Kupona Nharaunda neSiteji
Kune nzira dzakawanda dzakasiyana dzekutarisa pahupenyu hwehupenyu neHodgkin lymphoma. Ngatitarisei izvi nenzira shomanana.
Kuwanda kwehutano hwehupenyu hunopa hupenyu hwekutarisira kwevanhu vane zvikamu zvose zvakabatana zvinosanganisira:
- 1-gore rose kupona kwehupfumi ye 92 muzana
- Kwemakore mashanu kuponeswa kwemazana ezana 87 muzana
- Makore gumi ekupona kwehuwandu hwe80%
Makore mashanu ekupukunyuka matanho nechikwata anosanganisira:
- Nhanho I makore mashanu ekupukunyuka ndiwo 90 muzana
- Chikamu II makore mashanu ekupukunyuka ndiwo 90 muzana
- Chikamu III-makore ekupona kwegore makore makumi mapfumbamwe
- Nhanho IV makore mashanu ekupukunyuka ndiwo 65 muzana
Zvakakosha kucherechedza kuti aya mahara ndeyveruzhinji rwevanhu vose vane imwe nzvimbo yehutachiona hweHodgkin pasinei nezera ravo uye zvisinei nezvimwe zviitiko zvingawedzera kana kuderedza mukana wekupona.
Kubvira Kwenguva Yakareba NeHodgkin Lymphoma
Kurarama kwenguva yakareba neHodgkin lymphoma zvakaoma kuenzanisa, zvichienderana nemamiriro ezvinhu akadai sechipiri chekenza iyo inogona kuitika makumi emakore mushure mekurapa. Izvozvo zvakati, zvidzidzo zvakasiyana zvinofungidzira kuti pane imwe nguva pakati pemakore gumi nemashanu nemakumi matatu kubva pakurapa, vanhu vane Hodgkin lymphoma vanogona kufa nekuda kwechikonzero chisingawirirani neHodgkin lymphoma kupfuura kubva kuHodgkin. Mune mamwe mazwi, mushure mekunge nguva iyi yevanhu vanhu vangangodaro vafa nezvikonzero zvinowanzoita kuti vanhu vakawanda vanofa kubva.
Zvimwe Zviitiko Zvinoponesa Kupona NeHodgkin Zvirwere
Kune zvakawanda zvinoshandiswa zvinosanganiswa nemukana wekuwedzera kana wokuderera wekupona Hodgkin chirwere. Zvimwe zvezvi zvinosanganisira:
- Chikamu chechirwere - Chirwere cheState I kana II chinotakura chirwere chinopfuura chigadziko chechitatu kana ganhuro IV.
- Zera - Vaduku vanowanzoita zviri nani kune avo vakwegura (vanopfuura makore makumi mashanu).
- Zvepabonde - Vakadzi vanowanzova netariro yakakura yehupenyu kupfuura varume.
- Kuvapo kwezviratidzo zveB - Kurasikirwa nekurema, usiku, uye fever, izvo zvinonzi B zviratidzo zve lymphoma , zvinosanganiswa nehurombo hwehurombo (asi zvakadaro, vanhu vazhinji vanogona kubudirira kurarama kwenguva yakareba).
- Kunyangwe kudzoka kunowanikwa uye-Kana kune avo vanodzoka zvakare mugore rokutanga vachitevera kurapa, kufungidzira kwakaipa.
- Mhinduro kumushonga - Avo vanopindura mushonga wekutanga-line vanove nemaonero akanaka kune avo vasingaiti.
- Albumin level - A low albumin level (vasingapfuuri 4 g / dL) inosanganiswa nehuwandu hwehurombo.
- Sero rega rega rega (WBC) - Chikwata chepamusoro chekuyera ropa (yakakura kupfuura 15,000 masero eropa pamam3) inobatanidza nehuwandu hwehurombo.
- Low absolute lymphocyte count (ALC) - An absolute lymphocyte count inopfuura masero 600 pamam3 inosanganiswa nehurombo hwehurombo.
- Chirwere chinotapukira chinokonzerwa nehuwandu huri nani.
- Anemia - A low hemoglobin (pasi pe10,5 g / dL) inobatanidza nehuwandu hwehurombo kune avo vane hemoglobin yakakwirira.
- Sed rate - An erythrocyte sedimentation rate (ESR) inopfuura 30 inosanganiswa nehurombo hwehuwandu.
- Rudzi rweHodgkin lymphoma - Mamwe maitiro eHodgkin lymphomas anowanikwa nehupenyu hwakanaka kupfuura humwe ( nodular lymphocyte yakanyanya uye nodular sclerosing marudzi ane maitiro akanaka zviri nani).
- Utano huzhinji panguva yekuongororwa uye mamwe marapirwo
- Pasinei nokuti kenza inowanzoitika kana kuti inofambira mberi
- Inishuwarenzi yehutano - Vanhu vasina uine inshuwarhu yehutano vane hutano husina hurombo.
Kudzokorora uye Kupona Mari
Sezvataona pamusoro apa, nguva uye nguva dzekudzokorora zvakasiyana zvakanyanya neHodgkin lymphoma kupfuura nekenza yemazamu. NeHodgkin lymphoma, zvinopfuura hafu yezvakadzokorora zvinowanikwa mukati memakore maviri ekutanga kurapwa uye kusvika 90 muzana inowanikwa musati makore mashanu. Kuitika kwekudzoka shure kwemakore gumi isingakoshi uye pashure pemakore gumi nemashanu dambudziko rekuwedzera lymphoma rakafanana nehuwandu hwehuwandu hwehuwandu hwevanhu. Kune avo vakanzwa nezvekenza yekamu inoramba ichidzoka mushure memazana emakore, inogona kuuya sevamwe vanovimbiswa kuti izvi hazvishamisi neHodgkin chirwere. Zvakakoshawo kuziva kuti kunyange nekudzoka, vanhu vakawanda vane chirwere cheHodgkin vacharamba vachirarama hupenyu hurefu.
Kufananidza Zvirwere Zvako
Kune avo vanoda kuva nehana iri nani pamusoro pekufungidzirwa kwavo kwekufungidzirwa, pane chizivo chinozivikanwa seHaveenclever chirevo chekutsanangurira iyo inoshandiswa kuenzanisa kufungidzira kunoenderana nenyaya zvinomwe dzakasiyana kana njodzi. Chimwe chezvinhu izvi zvinomwe zvinofungidzirwa kuti zvideredze makore mashanu zvichararama nekusvika makumi masere kubva muzana. Izvi zvinosanganisira serum albumin vasingapfuuri 40 g / dL, hemoglobin inopfuura 10,5 g / dL, chirume chechikadzi, chirwere chechitanhatu IV, chichena cheropa chinopfuura 15,000 / mL, uye lymphocyte inodarika 600 / mL.
Kune avo vasina chero chezvinhu izvi zvinokonzera ngozi, makore mashanu anofungidzirwa kufungidzira (yakazara) ndeye 89 muzana, uye kune avo vane 5 kana zvimwe zvinowanzoisa njodzi, inofungidzirwa kuti makore mashanu ekupukunyuka ndiwo 56 muzana.
Ramba uchifunga kuti zvishandiso izvi zvakare zvinoshandiswa kuenzanisa "chiyero" chirevo, uye hapana munhu akaenzana. Zvakakoshawo kuziva kuti kunyange kana uine zvishanu kana kupfuura zvinowanzoisa njodzi, vazhinji-vanopfuura 50 muzana yevanhu-vachiri vapenyu makore mashanu mushure mekunge vaongororwa.
Chii Chaunogona Kuita Kuti Uvandudze Matanho Ako?
Nezvose zvekukurukurirana nezvekusarudzwa kwemishonga, pane dzimwe nguva zviri nyore kukanganwa kuti kune zvinhu zvisiri nyore iwe unogona kuzviita iwe kuti uvandudze hutano hwako. Zvakakosha ku:
- Idya utano: Zvaunoisa mumuviri wako zvinogona kuita mutsauko mukunyatsokwanisa kutsungirira kurapwa uye kuti unonzwa sei mushure mekurapa. Kana iwe uri kutarisana nematambudziko, bvunza oncologist yako kuti akugadzirire iwe ne oncology nutritionist.
- Kudzidzira muviri: Isu iye zvino tine huwandu hwezvidzidzo izvo zvakatarisa kuguma kwekuita muviri nguva dzose pamusoro pemigumisiro yekenza dzakawanda dzakasiyana, kusanganisira Hodgkin lymphoma. Kunyange zvishomanana zvekurovedza muviri zvinobatsira. Ramba uchiyeuka kuti zviri nani kushandisa zvinowanzowedzera mune zviduku zvishoma pane kushandiswa kwenguva refu nguva shoma.
- Kurara zvakanaka: Hatisingazivi nezvemigumisiro yekushungurudzika kwehope pane chirwere cheHodgkin, asi tinoziva kuti nekenza yemazamu izvi zvinogona kuderedza kupona. Taura neo oncologist yako kana iwe uine izvi zvakasvibiswa pamagetsi ekurapa.
- Dza chirongwa chekuchengeta chirwere chepachirwere: Kana wapedza kurapwa, iva nechokwadi chokuti iwe nachiremba wako munozadza chirongwa chekuchengeta chirwere. Ngozi yekondari yechipiri ndeyechokwadi mushure mokurapa kwaHodgkin, uye inogona kuwedzera. Chiremba wako anogona kukurudzira kare kare kana kuwedzera kuongororwa kwekenza sekenza yepabonde uye kutevera pazviratidzo zveimwe kenza inofanira kuitika.
Hodgkin Lymphoma: Kazhinji Inoporesa, Kunyange Ichi Chirwere Chinorwadza
Zvinogona kunge zvisinganzwisisiki kune mumwe munhu asina kumbove nekenza, asi kune mutsara unopikisana pakati pevanhu vane maitiro akasiyana-siyana ekenza, kana pakati peavo vane huwandu hwakanyanya hwekupona uye hupenyu hwepasi hwekenza. Vaya vane kanza dzine maitiro ekudzivirira zvishoma vanogona kufunga nezvemamwe mararamiro anoramba aripo asingasviki.
Ramba uchifunga kuti kunyange zvazvo Hodgkin lymphoma inoporesa kupfuura dzimwe dzakawanda dzekenza, kutarisana nekenza ipi inotyisa. Kuva nehupfumi hwako hwakakandwa muchiso chako chimwe chinhu avo vasina kenza vanogona kusanzwisisa uye hazvina basa kana kenza ine 99% yehupenyu hwehupenyu kana kuti 2 muzana yehupenyu hwehupenyu. Tinofanira kuzivawo kuti, kunyange kana ichirapa, kurapwa kwekutonga Hodgkin lymphoma kunonetsa pane zvakanakisisa. Chemotherapy inogona kuramba yakareba kwenguva refu, uye kunyanya ne stem cell transplants, kusvika kune imwe huru, kupfuura kune dzimwe dzakawanda zvekenza. Panewo nyaya yemazuva mazhinji emigumisiro yeHodgkin lymphoma, yakadai semakondomu echipiri, izvo zvichatoda kuongorora nguva dzose.
Sezvinyorwa zvokupedzisira, kana iwe kana munhu waunoda wapfuura nemushonga weHodgkin chirwere, zvakakosha kutaura nachiremba wako nezvekugara. Makiriniki emukenza akawanda zvino ane zvirongwa zvekugadzirisa kenza zvekare zvinoshandiswa pakuguma kwekenza kurapwa , kubva pakurwadziwa kusingaperi kusvika kune kuzvidya mwoyo, zvakanyatsogadziriswa.
> Sources:
> Ahmadzadeh, A., Yekaninejad, M., Jalili, M. et al. Kuongororwa Kuwedzera Kwekupona uye Zvimwe Zvinyorwa Zvokurambana mushure mekubata Hodgkin Lymphoma Varwere vane Chemotherapy Regimens. International Journal yeHematology Oncology neStem Cell Research . 2014. 8 (2): 21-26.
> America Cancer Society. Cancer Chokwadi & Zviyero 2017. https://www.cancer.org/research/cancer-facts-statistics/all-cancer-facts-figures/cancer-facts-figures-2017.html
> Brenner, H., Gondos, A., uye D. Pulte. Kuponeswa Kutarisira Kwevarwere Kuwanikwa neHodgkin Lymphoma muna 2006-2010. The Oncologist . 2009. 14 (8): 806-813.
> National Cancer Institute. Kuongororwa, Epidemiology, uye Kuguma Zvabuda Purogiramu. SEER Cancer Statistics Review (CSR) 1975-2014. Yakabudiswa musi waApril 14, 2017. https://seer.cancer.gov/csr/1975_2014/