Kuenzanisa kupona kwemaMedhia kusvika kuAvhareji kupona
Chii chinorehwa neshoko rezvokurapa rokuti "kupona kwemuviri?" Ngatitarisei nguva uye nei iwe ungapiwa ruzivo pamusoro pekupona kwako kwemuviri, kuti iyo nhamba yakasiyana sei ne "kuponeswa mitengo" uye chii chaunofanira kuziva kana uri kunzwa uchizvidya mwoyo pamusoro pekutaura kwako.
Tsanangudzo: Kuponesa kweMedhia
Kupona kweMedhia kunotsanangurwa seye nguva inotevera iyo 50 muzana yevanhu vane chimwe chiitiko ichiri kurarama, uye 50 muzana vakafa.
Semuenzaniso, kuponeswa kwemuviri kwemwedzi mitanhatu kunoratidza kuti mushure memwedzi mitanhatu, 50 muzana yevanhu vane chirwere ichocho vachange vari vapenyu, uye 50 muzana ingadai yapfuura.
Apo Peri Median Survival Inogona Kushandiswa
Kune nzira dzakawanda umo iwe unganzwa izwi rokuti kupona kwemajeri rakashandiswa:
- Sezvinorondedzero yezvinobatsira zvekurapa.
- Sekufungidzira kwekufananidzira kwechiitiko. Semuenzaniso, kupona kwemuviri kunogona kushandiswa kurondedzera kufungidzira kwechirwere umo kuponeswa kwepamuviri kusina kukwana. Vanhu vanogara kwenguva yakareba sei?
- Sekuguma kwepfungwa mumutambo wekliniki .
Kuenzanisa uye kusiyanisa kupona kweMedhia kune zvimwe zviitiko
Kupona kwemaMidhi kunoshandiswa kutaura pamusoro pemishonga yakawanda yekenza. Inogona kuva inofanirwa kutarisirwa kupfuura yehuwandu hwehupenyu hwehuwandu hwehupenyu (huwandu hurefu hwomunhu mumwe munhu anorarama nemuenzaniso) apo pane kuchinja kwakasiyana-siyana mumatauriro anoita vanhu kumamiriro kana kurapwa.
Mamwe mazita mashomanana mamwe mazwi aunogona kunzwa anosanganisira kuponesa, kuwedzera-kusununguka-kusununguka uye zvimwe, izvo zvinorondedzerwa munyaya ino.
Kubatsira uye Kukanganisika kwekushandisa kuponesa kweMedan neCarcer
Pasina kupinda mukukurukurwa kwezviverengera, zvakakosha kuziva kuti chero huwandu hwemashoko hunokanganisa kana uchitsanangura kurarama kwehupenyu hwekenza, kana kubatsirwa kwekurapa.
Mienzaniso mishomanana inotaurwa pamusoro apa.
- Chibatsiro: Kurapa kunowedzera kupona nemazuva kana masvondo kana kunyange mwedzi, nguva yenguva refu yekupedza inogona kupa zviratidzo zviri nani kuti mushonga unoshanda sei. Semuenzaniso, chirwere chekufungidzira chinogona kuwedzera kupona kwemazuva mashoma nemwedzi mina - somuenzaniso, hafu yevanhu inogona kurarama kwemwedzi gumi nematanhatu pane mwedzi gumi nekurapa. Sezvo vanhu vazhinji vasingadi kurarama kwenguva yakareba, kuenzanidza sekuita kwemazuva mashanu ekupona kwemazana kana kunyange makore maviri ekupona kwemazana hakuzorevi ruzivo rwekurapa kupa vanhu 4 mwedzi (uye inotarisira zvakanaka) kuti vararame.
- A Kusakwanisa: Chimwe chiitiko chingaitika kana kurapa kwakaguma nemigumisiro yakanaka yakareba kwenguva refu, asi nechepasi pehafu yevanhu, pasi pemutsara. Kana vanhu vanopfuura hafu yevanhu vakafa mumakore maviri ekutanga kupona kwemukati kwaizova pasi pemakore maviri. Muchiitiko ichi, zvichida kugadzirisa kurapa, kana kubvumirwa mumakore maviri okutanga kungaita kuti vararame nguva refu. Mumuenzaniso uyu wezvinyorwa, zvinogona kuti 30 muzana yevanhu vakararama kwemakore mashanu mushure mekurapa asi 5% chete ndivo vakararama kwenguva refu vasina kurapwa. Muchiitiko ichi, makore mashanu okupona aizotaura zvakawanda pamusoro pekugona kwehutano kupfuura kuponesa kwemuviri.
Statistical vs Clinical Meaning of Survival Median
Zvakakosha kudzokorora izvo zvinorehwa zvinorehwa uye chiremba chinorevei hachisi zvimwe chetezvo. Nhamba inotsanangurwa (ichiti, vatsvakurudzi vanofara vanogona kuwana kubva pamugumisiro wekudzidza) vanopa ruzivo pamusoro pekuvimbika kwechidzidzo, asi chinangwa chechipatara chinotsanangura kukosha kweizvi kune vanhu mumwe nomumwe. Kune mhando dzakasiyana-siyana dzinofanirwa kutaridzirwa, dzakadai sehuwandu hwekuchinja mumararamiro ehupenyu, kuvhiringidzwa kwemishonga inoshandura kuponesa kwemuviri, pamwe nekusvibiswa.
Chimwe chiitiko chave chataurwa ndeye chezvimwe zvinodhaka zvinotarisirwa zvinoshandiswa zvepancreatic cancer.
Chimwe chidzidzo chakaratidzira kusanganiswa kwakawedzera kupona kwema median kubva pamwedzi 5.91 kusvika kumwedzi 6.24 kwaive nehuwandu hwekukosha, asi kwete zvekuchikoro. Mumuenzaniso uyu, kukosha kwekliniki ndeyekuti vanhu vaigara, pavhareji, mazuva gumi, uyewo vachitambura nemigumisiro uye mari yekurapa.
Mune zvimwe zviitiko, chidzidzo chingave chisinganyanyi kukosha kwezvakawandisa asi chinogona kunge chakanyanyisa zvipatara zvakasiyana; vanhu vaizoona kuchinja kukuru.
Nhamba iyi ndeyo NUMERI HERE Vanhu
Zvinonyanya kukosha kunyora kuti nhamba dzemhando ipi zvayo ndeyo nhamba chete. Vanhu vanosiyana zvakasiyana-siyana mune zvavanoita pamishonga uye kuti vanogara kwenguva yakareba sei nemishonga yakasiyana-siyana. Pane zvinhu zvakawanda zvinogona kumutsa kana kuderedza mukana weumwe munhu wekupona nekenza.
Zvinotonyanya kukosha kuti uone kuti nhamba ipi neipi yaunonzwa nezvekenza inowanzova nemakore mashomanana. Kufambira mberi kuri kuitwa mukurapa kenza. Iko-inotsanangurwa kuponeswa nhamba dzekenza yemapapu dzine makore mashanu. Izvozvo zvakati, kwaiva nemishonga yakawanda inogamuchirwa nemukenza wemapapu mukati megore ra2012 kusvika muna 2017, kupfuura mugore remakore makumi mana risati rasvika 2011. Ichi ndicho chimwe chezvikonzero zvakawanda zvokutsungirira pane tariro.
Mienzaniso:
Jack akaudzwa kuti kuponeswa kwemuviri kwevanhu vane chirwere chemukoko 3B yemukenza wemapapiro mwedzi 13. Izvi zvingareva kuti, nhamba yepamusoro, aiva ne50 muzana yemukana wokurarama nehosha yake mumwedzi gumi nematanhatu.
> Sources:
> Chiba, Y. Kaplan-Meier Curves yeKupona Cusal Effects neKuva-ku-Chiitiko Chiitiko. Clinical Trials . 2013. 10 (4): 515-21.
> Ranganathan, P., Pramesh, C., uye M. Buyse. Kusangana Kwezvivako muStatistical Analysis: Clinical Versus Statistical Significance. Zvirongwa muChitamende Ongororo . 2015. 6 (3): 169-170.