Lymphoma ikenza yemhando dzemasero machena anonzi lymphocytes. MALT lymphoma iyo isiri yomuitiro weusina Hodgkin lymphoma (NHL) . MALT inomirira "mucosa-associated lymphoid tissue." Kusiyana nemararamiro akawanda anotanga kukura mukati memakirinikodhi, rudzi urwu rwe lymphoma runowanzobva kune zvisikwa zvinowanikwa mune imwe nhengo dzomuviri.
Kune marudzi akasiyana e-lymphocytes, uye munhu anogona kukura lymphoma mune chero ipi zvayo. Kune B-lymphocytes uye T lymphocytes, semuenzaniso, uye naizvozvo, kune B-cell lymphomas uye T-cell lymphomas. MALT lymphoma inozivikanwawo se "extranodal marginal zone B-cell lymphoma," iyo inoratidza kuti iyo inonzi B-cell isiri Hodgkin lymphoma inomuka kwete kubva kumakirinikodhi asi kubva kune dzimwe nhengo.
Kuwanda
Nhoroondo yeLALP lymphomas inenge 5% yevose vasina Hodgkin lymphomas. Izvo zvinowanzoonekwa kune vakwegura asi zvinogona kuitika kune vanhu mumakore makumi maviri uye makumi matatu. Izvo zvishoma zvishoma pane zvevakadzi pane varume.
Akakanganiswa Nhengo
Nhengo inonyanya kugadziriswa muMALT lymphoma ndiyo mudumbu, iyo inokonzera inenge 2 pamatatu ose matatu. Apo MALT lymphoma inowedzera mudumbu, inogonawo kunzi "gastric MALT lymphoma." Asi dzimwe nhengo dzinobatwawo neLALT lymphoma.
Iyo mapapu, utachiona, zvipfeko zvinokonzera uye ziso rinogonawo kuchinjwa ne lymphoma iyi.
Zvinokonzera
MALT lymphomas yemudumbu inobatanidza nehutachiona hwehutachiona. Helicobacter pylori rudzi rwebhakitiriya runowanzokonzera mudumbu uye hunokonzera ulcers uye gastritis, kana kutsamwa uye kuputika kwemuviri wechipfu.
Mune vamwe vanhu, iyi bhakitiriya inogona kukonzera MALT lymphomas. Gastric MALT lymphoma haisi yakasiyana nenzira iyi mune dzimwe mhando dze lymphoma dzakabatanidzwa kune zvirwere nezvimwe mabhakitiriya, mavairasi, uye marasita . Izvi zvinonzwisisika kana iwe uchifunga nezve lymph system, kusanganisira lymphocytes, sechikamu chemuviri wezvirwere mumuviri unoedza kuziva uye kurwisa zvipenyu zvekunze mumuviri wedu. Munyika yose, inenge 20% yekenza inobatana nehutachiona. Zvimwe zvinokonzera mALT lymphomas zvinosanganisirawo utachiona neClamydophilia psittaci, uye zvirwere zvinotapukira.
Maitiro
MALT lymphomas inotsika-grade lymphomas. Dzinokura zvishoma nezvishoma uye dzinoramba dzakasungwa kune imwe nhengo kwenguva yakareba. Apo pavanotaura nezvemymphomas inokura zvishoma nezvishoma, oncologists vanowanzoshandisa izwi rokuti 'indolent.' Ruzhinji rwevarwere vane MALT lymphoma vanoonekwa kare kare chirwere chisati chapararira kune dzimwe nhengo uye lymph nodes.
Zviratidzo
Zviratidzo zveMALT lymphoma zvinovimba nhengo inobatwa. Apo MALT lymphoma inokanganisa mudumbu, unganzwa uchitsigirwa kana iwe unogona kuora kurasikirwa; matanda madema anokwanisa zvakare nekuda kwekubuda ropa mudumbu. Vamwe vanhu vanogona kunzwa kurwadziwa kusina kujeka mudumbu.
Kuziva
Kuti aongorore MALT lymphoma, chiremba achada kutora biopsy kubva mumarara. Kune MALT lymphomas yemudumbu, izvi zvinowanzobatanidza kugumira kwenguva. Vanachiremba vachaedza zvakare kuvepo kweH H. pylori mabhakitiriya mudumbu. Mimwe miedzo inofanira kudiwa inosanganisira kuongororwa kweropa, kuongorora kwemuviri uye chifuva, uyewo kuongorora kwemapfupa .
Staging
Iko kusangana kwe lymphomas kunosanganisira zvitatu zvakasiyana. MALT lymphomas inotanga kuiswa muzvikamu zvakasiyana-siyana, kubva pachitsauko I kuenda kunechitanhatu IV zvichienderana nekuwanda kwavari. Ipapo tsamba A kana B inopiwa zvichienderana nezviratidzo.
Panewo mamwe mazita maviri, E uye S, umo E inomiririra 'kuwedzera kupfurikidza' kana kunze kwe lymphatic system, uye S inomiririra kuvapo kwekenza mupleen. MALT lymphomas haigoni kubuda muine lymph nodes, uye haawanzopararira kune dzimwe nhengo. Zvizhinji zveMALT lymphomas zvinowanikwa muChechi IE, zvichireva kuti varipo mune imwe nhengo uye kuti iri kunze kwemuitiro we lymphatic. Kunongova 20% yeMALT lymphomas inenge yakanyanyisa kuongororwa.
Mishonga
Kurapa kweMALT lymphomas kunoenderana nhengo inobatanidzwa uye danho rekuongororwa. Muchiremba vazhinji, kurapa kwepanyika kwakafanana nemayera kana chirwere chinogona kukwana kugadzirisa chirwere chacho, asi chirongwa chekemikirwo sechem chemotherapy chinowanzoshandiswa kune yakakwirira yekenza uye inogona kushandiswa kuderedza dambudziko rekudzokorora nekenza yekare.
Kurapa kweMALT lymphomas yemudumbu kunosanganisira kupedza utachiona neH H pylori. Izvi chete zvinokwana kubvisa kenza muhuwandu hwevanhu.
Shoko Rinobva
Kushandisa chemotherapy kweMALT lymphomas hauna kuongororwa zvakafanana nemamwe lymphomas. Munguva yakapfuura, yakange iri tsika yekushandisa rudzi rwemakemikirini inoshandiswa pakaderera-grade-non-Hodgkin lymphoma. Mumamiriro ezvinhu apo maantibhakitiriya anorasikirwa, kune chibvumirano chakanaka pamusoro pekuti chemotherapy inofanira kushandiswa, asi zvishoma kubvumirana pamusoro pechirongwa chetano rehutano.
Sources:
Nakamura, S., naT. Matsumoto. Chirongwa cheGastric Mucosa-Associated Lymphoid Tissue Lymphoma. Gastroenterology Makliniki eNorth America . 2015. 44 (3): 649-60.
Raderer, M., Kiesewetter, B., Ferreri, A. et al. Clinicopathologic maitiro uye kurapwa kwemukati mahara lymphoma ye mucosa-associated lymphoid tissue (MALT lymphoma), CA: A Cancer Journal for Clinicians . 2015 Nov 24. (Epub mberi kwekudhinda).