Vanenge mamiriyoni 5,3 vokuAmerica vari kurarama nechirwere cheAlzheimer ; kunyange zvazvo vazhinji vavo vari vakuru, vanenge 5% vane chimiro chechirwere chinonzi early-onset Alzheimer's . Izvi zvinogona kuwanikwa mune vanhu vari mumakore makumi matatu, makumi mana, uye makumi mashanu.
Kunyange zvazvo kutanga-kutanga chirwere cheAlzheimer chisingawanzoitiki, avo vanofungidzira kuti ivo kana kuti vadiwa vanofanirwa kutsvaga mazano echiremba pakarepo, pasinei nezera.
Mamwe mishonga inoratidza zvivimbiso zvinokurudzira kuderedza kufambira mberi kwechirwere. Uye kunyange zvazvo chirwere ichi chiri chinotyisa, nzira inogadzirisa haisi kungoshanda chete asi inogona kupa avo vane humwe pfungwa dzekutonga pane zviri mberi.
Zvose zvirwere zveAlzheimer zvinosanganisira kufambira mberi kwemasero europi, zvichibva nehappocampus , nzvimbo yeuropi inobata zvirangaridzo , uye cerebral cortex, iyo inoshandiswa pakuita zvisarudzo nekufungidzira. Masayendisiti haazive chinokonzera kuora kana kuti nei kupfuurira kwechirwere ichisiyana zvikuru pakati pevanhu. Zviitiko zvakawanda zvekupedzisira-kutanga kweAlzheimer's disease, kazhinji inowanikwa mune vanhu vanopfuura makore makumi matanhatu nemashanu, ndizvo izvo vatsvakurudzi vanodana "sporadic" kana kuti kwete chaiyo inhaka, kunyange chikonzero chisina kuonekwa. Zvisinei, vanotsvakurudza vanobvumirana kuti inenge yose inotanga-kutanga kweAlzheimer's disease inotora nhaka.
A Strong Genetic Link
Inhaka yeAlzheimer inonziwo chirwere cheAlzheimer's disease (FAD). Maererano neNational Institute on Aging, kana mubereki ane chimiro chemhuri chekutanga-kutanga kwechirwere cheAlzheimer, vana vake vane mikana ye50% yekuvandudza mamiriro acho ezvinhu.
Kuchinja-chinja mumakemikari matatu akabatanidzwa kumhuri, kutanga-kutanga kweAlzheimer's disease.
Aya mazamu ave akanyorwa zita re PS1, PS2, uye APP nevanotsvakurudza.
Kutsvakurudza kubva kuma1991 kunoratidza kuti kuchinja kwegene rinonzi PS1 kunogona kutakura 30% kusvika ku60% yezvokutanga zveAlzheimer's cases. Kutsvakurudza kutsva hakusakanganisi maererano nehuwandu hwehuwandu hwezvinhu zvakasiyana-siyana, asi hunosimbisa kuti gemu re PS1 ndiyo inonyanya kuwirirana neFAD.
Zvinokwanisika kuongorora zvirwere zvemajeni aya, asi pane zvakawanda zvinobatsira uye zvinopedza kuita kudaro, kubvira pakukwanisa kupa huno ruzivo rwehutano hwehutano kuvana vako kurarama neruzivo rwekuti Alzheimer isingagoneki. Mumwe chiremba anovimba kana kuti mazano ekurapa anogona kukubatsira kuti uone kana kuongorora mazita ekuberekwa kwakakunakira iwe kana mudiwa. Iva nechokwadi chekutarisa neinishuwarenzi yako isati yatanga kuongororwa, nokuti kugoverwa kwemari yekuedza kunosiyana, uye mamwe maitiro haabhadhara chero ipi zvayo.
Zviratidzo Zvinonyevera
Zviratidzo zvekutanga zvechirwere cheAlzheimer's disease zvakafanana neyekupedzisira-kutanga kweAlzheimer's. Zviratidzo izvi zvinosanganisira kugara tichirasikirwa nezvinhu, zvakaoma kuita mabasa akafanana, kukanganwa, hupenyu hunochinja , kuvhiringidzika, kusaruramisira , zvinetso nekutaurirana kukurukurirana uye mutauro, kusununguka kwevanhu uye zvinetso zvinotevera nzira dzakananga.
Dzimwe nyanzvi dzinofunga kuti chirwere ichi chinowedzera nokukurumidza pakati pevaya vane chirwere chekare. Zvisinei, vamwe vanopikisa kuti chirwere ichi chinongowoneka chichifambira nokukurumidza kune avo vane maitiro ekutanga-kutanga kwechirwere cheAlzheimer nokuti vaduku vangave vane hutano hwakanaka. Saka, zviratidzo zvinogona kutora nguva refu kuti zvionekwe.
Kuongorora nekurapa
Kunyatsoongorora kusati kwasvika kweAlzheimer's hakuna kumbosiyana nekupedza-kutanga kuongorora. Nemhaka yokuti hapana chiyero cheAlzheimer, vanachiremba vanoita basa rokutonga kunze kwezvimwe zvinokonzera zviratidzo. Nzira imwechete yekugadzirisa zviratidzo zveAlzheimer ndeyekuongorora maitiro ehupi mushure mekufa.
Maererano neFisher Center yeAlzheimer's Research Foundation muNew York, chiremba acharamba achiedza miedzo inotevera apo achiongorora murwere weAlzheimer's disease:
- Kliniki yekuongorora kusanganisira ropa, zviratidzo uye kuongorora kwekunzwa.
- Nhoroondo yezvechiremba inosanganisira mitemo yazvino uye kushandiswa kwezvinodhaka zvinodhaka pamwe chete netsanangudzo yakajeka yevanenge vachifungidzirwa zviratidzo.
- Dhiyabhorosi miedzo inosanganisira kushushikana kweglucose , kuongororwa kwetachiona , nekuzara kweropa. Chiremba anotarisa kuona kana chimwe chirwere chingave chiri chekutakura zviratidzo.
- MRI kana CT scan yeuropi kuwana ropa kana mabheya angave achikonzera zviratidzo.
- Kuongororwa kwechiuropiyyrological umo vanachiremba vanopedza miedzo kuti vaongorore kutarisa nguva, kubatana, kuyeuka uye kukwanisa kugadzirisa matambudziko. Iyi miedzo ichapa kuongorora kwakajeka kwezviratidzo zvemunhu.
Kurwisana nekutanga-kutanga kwechirwere cheAlzheimer kunoda rubatsiro rwemhuri neshamwari, uyewo nekuchenjerera kuronga kutarisira kwenguva refu uye kuti ungaripa sei.
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"Dambudziko reAlzheimer's Fact Sheet." National Institute on Aging. 26 Gumiguru 2007. US National Institutes of Health. 22 May 2008.
"Dambudziko reAlzheimer Genetics Fact Sheet." National Institute on Aging. 26 Gumiguru 2007. US National Institutes of Health. 22 May 2008.
"Chokwadi cheAlzheimer uye Zvifananidzo." ALZ.org . 2008. Alzheimer's Association. 22 May 2008.
Bell, Karen, Mary Sano, Davangere P. Devanand, Lawrence S. Honig, Penne Sims, Scott A. Small, Jennifer Williamson-Catania uye Daniel G. Fish. "Dhementia: Kuvandudzwa kweMurangi." Columbia University: Kuenderera mberi Dzidzo . 1 Mar. 2004. University University. 22 May 2008.
"Kurarama Nezvirwere Zvokutanga zveAlzheimer's." Cleveland Clinic Health System . 14 Jun 2006. Cleveland Clinic. 22 May 2008.
"Kusunungura Chakavanzika." National Institute on Aging. 28 Jul. 2007. US National Institutes of Health. 22 May 2008.