Ikoko hippocampus inzvimbo yeuropi iri pasi pemazuva mashoma ezere lobes. Izvo zvakafanana pakugadzirwa kwegungwa, uye kune rimwe kune rumwe rutivi rweuropi pamusoro pemakanzwa.
Zvinoita
Iko hippocampus inotibatsira kuti tive nekurangarira zvitsva. Iko dzimwe nguva inoonekwa senzira yekuyeuchidza sokunge kuti zviyeuchidzo zvinoda kudarika mukipikipu kuitira kuti igone kuchengetwa mubhuku rekuyeuka kwenguva refu .
Imwe tsvakurudzo yakaratidzawo kuti hippocampus inokosha kwete kungoita zvichedzo zvitsva asi zvakare kugadzirisa zviyeuchidzo zvekare.
Zvinofadza kuti hippocampus kurutivi rworuboshwe kazhinji ine basa guru mukuyeuka uye mutauro kupfuura uyo ari kurudyi.
Zvirwere zveAlzheimer Zvinobata Sei Hippocampus
Kutsvakurudza kwakawana kuti imwe yenzvimbo dzekutanga muuropi dzakabatwa nechirwere cheAlzheimer is hippocampus. Masayendisiti akabatanidza atrophy (shrinkage) yenharaunda ye hippocampal nekuvapo kwechirwere cheAlzheimer. Atrophy munharaunda iyi yeuropi inobatsira kutsanangura kuti nei imwe yezviratidzo zvekutanga zvechirwere cheAlzheimer inowanzoshaya kuora kwekuyeuka, kunyanya kuumbwa kwezviitiko zvitsva.
Hippocampus atrophy yakabatanidzwawo nekuvapo kwepuroteni yemaprotheni inovaka sezvo chirwere cheAlzheimer chiri kufambira mberi.
Unyoro Hwekushaya Njere
Saka, ukuru uye huwandu hwemukoko hunoonekwa zvakajeka nechirwere cheAlzheimer.
Asi zvakadini nehutachiona hwekushaya njere, imwe nguva, asi kwete nguva dzose, inofambira mberi kuAlzheimer's disease?
Zvidzidzo zvakaratidza kuti atrophy yemu hippocampus inobatanidza nekunzwisisa kusagadzikana kwepfungwa . Zvechokwadi, ukuru hwemukoko uye chiyero chekugadzirisa kwayo kwakaratidzwa kufanotaura kana MCI inofambira mberi kuAlzheimer's disease kana kwete.
Nhamba duku yeiyo hippocampal uye inokurumidza kukurumidza kana shrinkage correlate pamwe nekuvandudzirwa kwekushaya mungozo.
Ko Hippocampal Volume inogona Kusiyanisa Pakati Pezvinhu Zvakasiyana zveDhementia?
Tsvakurudzo dzinoverengeka dzekutsvakurudza dzakayera huppocampal volume uye yakatarisa kuti yakabatana sei nedzimwe mhando dzehutano hwemagumisiro. Chimwe chiitiko chaiva chokuti vanachiremba vaigona kushandisa huwandu hweatrophy munzvimbo inonzi hippocampal kuti vaone zvakajeka kuti ndechipi chinonzi dementia chaivepo.
Semuenzaniso, kana chirwere cheAlzheimer chaiva chimiro choga chekutemwa kwemaitiro chakakonzera kukura kwemukoko, izvi zvinogona kushandiswa kunyatsoona kuti Alzheimer's. Zvisinei, zvidzidzo zvakawanda zvakaratidza kuti ichi chiyero hachiwanzobatsiri pakusiyanisa marudzi mazhinji ehutementi.
Chimwe chidzidzo chakabudiswa mubhuku rinonzi Neurodegenerative Diseases chakacherechedza kuti kuderera kwemajipocampus kwakaitika muutementia .
Chidzidzo chechipiri chakawana kuti kupera kwechikafu chechiedza chakanga chakawirirana ne frontotemporal dementia .
Masayendisiti akawana misiyano yakakura, zvisinei, pakuenzanisa Lewy mumuviri wekutenda neAlzheimer's disease. Lewy muviri wekuora mwoyo kunoratidza zvishoma nezvishoma atrophy munzvimbo dzenharaunda muuropi, iyo inobatanidzawo nemigumisiro isingakoshi pamusoro, kunyanya mumatanho ekutanga eLeyy body dementia .
Iwe Unogona Kudzivirira Hippocampus Yako kubva Kuderera?
Iyo plastiki (izwi rokuti ubongo hukwanise kukura nekushandura kwenguva yakareba) ye hippocampus yakaratidzwa kakawanda mukutsvakurudza. Kutsvakurudza kwakawana kuti, kunyange zvazvo hippocampus inowanzoita atrophy patinenge takura, zvose zvekurovedza muviri uye kugadzirisa mafungiro (mafungiro emagariro) zvinogona kunonoka kuti shrinkage uye, dzimwe nguva, kunyange kuidzosera.
Sources:
Cleveland Clinic. Temporal Lobe. http://my.clevelandclinic.org/anatomy/brain/ns_overview.aspx
Dementia uye Geriatric Cognitive Disorders. 2010; 29: 294-300. Kusanganiswa kweHippocampal Volume uye Cerebrospinal Fluid Biomarkers Kunovandudza Predictive Value muKusava Nenyonganyonga Hwepfungwa. http://www.karger.com/Article/Abstract/289814
Dementia uye Geriatric Cognitive Disorders. 2012; 34 (1): 44-50. Kufananidza hippocampal atrophy muAlzheimer's dementia uye chirwere chekushaya pfungwa nemitumbi isina kunaka. http://www.ncbi.nlm.nih.gov/pubmed/22922563
Nhoroondo yezvirwere zveAlzheimer. 2013 Jan 1; 36 (1): 57-66. doi: 10.3233 / JAD-122293. Inonzi hippocampal ivhu rakanaka here kuti iparadzise chirwere cheAlzheimer kubva pakatarisana nekutengesa kwepfungwa? http://www.ncbi.nlm.nih.gov/pubmed/23542864
Kurasikirwa Kwepfungwa uye Brain. Hippocampus. http://www.memorylossonline.com/glossary/hippocampus.html
Nature Nature Neurology 8, 189-202 (April 2012). Zvinhu zvinogona kushandiswa zvinoshandura hukuru hwechi hippocampus nokukwegura.
Neurodegenerative Diseases. 2011; 8: 465-469. Hippocampal Atrophy mu Subcortical Vascular Dementia. http://www.karger.com/Article/FullText/326695
Neurology. March 17, 2009 vol. 72 no. 11 999-1007. Hippocampal atrophy rates muAlzheimer's disease. Yakawedzera kukosha pamusoro pehutano hwehutano hwehutano. http://n.neurology.org/content/72/11/999