Kusadya, Doro, uye Kuwedzerwa Kunobatsira Kuita Ngozi Yako
Gout chirwere cheArthritis chinoratidzwa nekurwiswa kamwe kamwe, kwakakomba kwekunzwa nekurwadziwa muzvibatanidza, kazhinji kacho chigunwe chikuru. Kunyange zvazvo zvimwe zvikonzero zvingakonzera kuti uwane chirwere ichi, chakadai sejenetics kana chirwere chisingaperi chepfungwa, vamwe vakaita sekudya, doro, uye kuneta kunogona kubatsira zvakanyanya.
Kakawanda, vanhu vachawanzoona kurwa kwavo kwekutanga pakati pemakore makumi matatu nemakumi mashanu.
Kunyange zvazvo varume vakawanda vanowanzove neve gout kupfuura vakadzi, njodzi kuvakadzi inogona kukura zvakanyanya mushure mekuguma kwemwedzi.
Zvokudya Zvinokonzera
Kusiyana nedzimwe mhando dzeArthritis , gout inokonzerwa nekusawirirana mumuviri wemetabolism panzvimbo yehutachiona hwemuviri. Ngozi ye gout inobatanidza nezvinhu zvakasiyana siyana-genetic, zvechiremba, uye mararamiro-izvo pamwe zvinobatsira pakusimudza uric acid muropa, mamiriro ezvinhu atinotaura sehuwandu hwehutachiona .
Zvokudya zvatinodya zvinoita basa rinokosha pakuvandudza zviratidzo zvegout. Izvi zvinokonzerwa nehurukuro yakawanda kune chigadzirwa chemunhu chinowanikwa mune zvokudya zvakawanda zvinonzi purine. Kana ichidyiwa, purine inoputswa nemuviri uye inoshandurwa kuva dhayi, uric acid . Pasi pemamiriro ehutano, ingadai yakasvibiswa kubva muropa neitsvo uye yakadzingwa mumuviri kuburikidza nemuyo
Kana izvi zvisingaiti uye iyo uric acid inotanga kuunganidza, inogona kugadzira zvinyorwa zvakanyatsogadziriswa pamwe chete uye zvinotungamirira kune gout attack.
Zvimwe zvokudya uye zvinwiwa zvinowanzokonzera izvi. Pakati pavo:
- High-purine foods inonzi inonyanya kuisa njodzi yegout. Izvi zvinosanganisira kudya sechirongwa chekudya, bhakoni, veal, uye mamwe marudzi ezvokudya zvegungwa
- Bheri inonyanya kuoma sezvo inogadzirwa nembiriso ye brewer, chigadziro neine purine yakakwana. Doro, kazhinji, inogumira sezvo inoshingaira kukurudzira uric acid maitiro ekugadzirwa.
- Zvokudya zvepamusoro-fructose, kusanganisira sodas uye zvinotapira zvinwiwa zvezvibereko, zvinogona kukonzera hyperuricemia sezvo shuga yakanyanyisa inokanganisa kuwedzerwa kweuric acid kubva kuitsvo.
Genetic Causes
Genetics inogona kuita basa rinokosha mumatambudziko ako gout. Hereditary hyperuricemia ndeimwe yakadaro, yakakonzerwa neSLC2A9 uye SLC22A12 mutations inotungamirira kumunhu asina simba (renso) basa. Apo izvi zvinenge zvichiitika, itsvo hazvikwanise kuisa uric acid kana kuti kubvisazve uric acid crystals kubva muropa.
Kusakwanisa kuchengeta kuenzana pakati pehuwandu hweuric acid hunogadzirwa uye kuti zvakadini zvinodzingwa uye pakupedzisira zvinotungamirira ku hyperuricemia.
Zvimwe zvirwere zvemajeni zvakabatana ne gout zvinosanganisira:
- Hereditary fructose kusawirirana
- Kelley-Seegmiller syndrome
- Lesh-Nyhan syndrome
- Medullary cystic chirwere chepfungwa
Zvokurapa Zvinokonzera
Pane humwe hutano hunogona kukugadzirira iwe gout. Zvimwe zvakananga kana zvakashata zvinoshandisa real function, asi vamwe vanoratidzwa nekusava nekuputika kwemaitiro apo mamwe masayendisiti anotenda anogona kukurudzira uric acid kugadzirwa.
Zvimwe zvezvinowanzozivikanwa zvehutano zvinokonzera zvinosanganisira:
- Chirwere chisingaperi chepfungwa
- Congestive heart failure
- Chirwere cheshuga
- Hemolytic anemia
- Hypertension (high blood pressure)
- Hypothyroidism (low thyroid function)
- Lymphoma
- Psoriasis
- Psoriatic arthritis
Zvimwe zviitiko zvezvokurapa zvinozivikanwa kuti zvinokonzera gout kushorwa, kusanganisira kushungurudzika pamwe kwekukuvadza, chirwere, utachiona huchangobva kuitika, uye kudya kwekuparara (iyo yekupedzisira iyo inogona kuwedzera uric acid maitiro nokuda kwekukurumidza kuderera kwemuviri wemuviri).
Mishonga Inokonzera
Imwe mishonga inobatanidza nehutachiona hwemhuka kana nokuti ine chirwere chekuvadza (kuwedzera kuwanda kweuric acid) kana kuparadza simba rekuita. Zvivi zvinowanzozivikanwa zvinosanganisira:
- Aminophylline (shandisa kurapa chirwere chisingagumi)
- Cyclosporine (an immune suppression drug)
- Ethambutol (yakashandiswa kurapa tuberculosis)
- Lasix (furosemide)
- Levodopa (yakashandiswa kurapa chirwere chePalinson)
- Low-dose aspirin (inoshandiswa kuderedza mwoyo yekutengesa ngozi)
- Niacin (vitamini B3)
- Thiazide diuretics (inoshandiswa kuporesa ropa rakanyanya kana chirwere chemwoyo)
Lifestyle Risk Factors
Zvisarudzo zvaunoita muhupenyu zvinobatsira zvikuru mumatambudziko ako ekutura sezvikonzero zvausingagoni kudzora, makore akadaro kana zvepabonde. Dzinogona kunge dzisingabvisi zvachose njodzi yako, asi dzinogona kukanganisa kuti kazhinji uye zvakanyanya sei unosangana nekurwisa.
Kuwedzera muviri
Mukuru pakati pezvinetso izvi kuneta. Pamusoro payo, kuwandisa muviri kunorema kubvisa kubviswa kwaUric acid kubva mumuviri. Uye, paunowedzera kuyera, hukuru huno huputsika huchava.
Insulin kudzivisa ndeimwe yekufambisa kwemasimba mushure meiyi inotyisa. Kana iwe uri kunyanya kuwandisa kana kuora, muviri wako unowedzera insulini yakawanda. Nhamba dzakakwirira dze insulin dzinotungamirira kuhutachiona hwakanyanya hunoita kuti pave nepamusoro mazinga eurric acid.
Chidzidzo che2015 chakawanawo kuwirirana zvakananga pakati pemakumbo evanhu uye pangozi yake yegout. Maererano nevatsvakurudzi, pakati pevanhu vane gout, avo vane mazamu akawanda emakumbo vane 47.4 muzana wekuda kwekurwiswa kana vachienzanisa neavo vane zvikwata zvemazuva ose vane ngozi ye27.3%. Izvi hazvina basa nemunhu wemuviri mazita (BMI), zvichiratidza kuti mafuta akawanda atinotakura, anotowedzera ngozi yedu yezviratidzo.
Zvimwe Zviitiko
Kubva pane hutano hwehutano hunoonekwa, dzakawanda zvezvinhu zvakafanana zvinosangana nezvirwere zvisingaperi zvisingaiti chirwere chechirwere cheshuga uye chirwere chemwoyo chinosanganiswa negout. Izvi zvinosanganisira:
- Mafuta akawanda emukadzi (mazamu emuviri)
- High blood pressure (pamusoro pe 130/85 mmHg)
- High LDL ('bad') cholesterol uye pasi HDL ("yakanaka") cholesterol
- High triglycerides
- Insulin kushorwa
- Nguva dzose kushandisa doro
- Sedentary lifestyle
> Sources:
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> Rothenbacher, D .; Kleiner, A. Koenig, W. et al. "Ukama huri pakati peClammatory Cytokines uye Uric Acid Levels neMagumisiro Emigumisiro Mwoyo muvarwere vane Stable Coronary Heart Disease." PLoS One. 2012; 7 (9): e45907. DOI: 10.1371 / magazini.pone.0045907.
> Roughley, M .; Bhercher, J .; Mallen, C. et al. "Gout uye mungozi yezvirwere zvepfungwa dzisingaperi uye nephrolithiasis: meta-kuongorora kwekuongorora zvidzidzo." Arthritis Res Ther. 2015; 17 (1): 90. DOI: 10.1186 / s13075-015-0610-9.