Uric acid inobudiswa apo muviri unoputsa purines (purines inopa chikamu chemakemikari ejeni redu). Iviri carbon-nitrogen ring bases, adenine, uye guanine, ndeye purines. Purines inoshumira sechimiro chemasimba kumasero uye inofanirwa pakugadzira DNA neRNA, mapuroteni, starch, mitemo ye enzymes, uye kushandiswa kwesero.
Uric acid inogadzirwa yakabatana nehuwandu hwe purines mukati memuviri uye kubudisa purine kudya.
Mune mamwe mazwi, purines inowanikwa mumarudzi ose evanhu uye inowanikwa mune zvokudya zvakawanda . Apo masero anofa mumuviri wedu, purines inosunungurwa. Uric acid ndiyo mugumo wemugumo kana munhu purine metabolism. Kuparadzaniswa kweUric acid kubva mumuviri kunobva pane zvishoma. Icho chiyero-pakati peuric acid nekugadzira-iyo inotarisa serum urate level (urric acid level muropa).
Serum Urate Levels
Kazhinji uric acid inoputika muropa uye inofamba ichienda kune itsvo kuti ibudiswe mumuguta. Kazhinji, vanhu vanochengetedza saruum urate yepamusoro pakati pe4 ne6,8 mg / dl, uyewo muviri wose uric acid we1000 mg. Vanhu avo vanokwanisa kubudisa uric acid yakawanda kana kuti vasingakwanisi kubvisa uric acid yakakwana vane huwandu hwakawanda hwema serum urate. Nhamba yakakwirira yeUric acid muropa inozivikanwa se hyperuricemia . Kunyanya kudyidzana kana pasi-kunze kweuric acid, kana kusanganiswa kwezvose zviri zviviri, kunogona kutungamirira ku hyperuricemia.
Vanhu vane hurefu hwakanyanya hweUric acid muropa vanogona kukura chirwere chetsvo kana gout kuburikidza nekugadzirwa kwemakristani muzvibatanidzwa. Haasi munhu wose ane hyperuricemia anovaka gout kunyange.
Zvakakosha kuchengetedza chirwere chemaitiro chinowanikwa. Kuongorora ropa ndeimwe nzira yekuongorora uric acid yako. Inogonawo kuongororwa pamushamba muenzaniso.
Zvakakodzera, serum uric acid inofanira kuva 6.0 mg / dl kana pasi. Munhu ane uric acid level ye 6.8 mg / dl kana yakakwirira inoratidzika seine hyperuricemia.
Hyperuricemia inogona kuitika nemamiriro akasiyana-siyana, kusanganisira:
- acidosis
- kudhakwa
- nemigumisiro ye chemotherapy
- gout
- chronic gouty arthritis
- chirwere cheshuga
- hypoparathyroidism
- inotyisa chepfu
- leukemia
- kidyo chirwere
- kidyo kutadza
- polycythemia vera
- purine-rich diet
- toxemia inobata pamuviri
Kuderera kweuric acid kunogona kubatanidzwa ne:
- pasi purine kudya
- Fanconi syndrome
- zvisina kukodzera antidiuretic hormone secretion
- Wilson chirwere
The Bottom Line
Zvakakosha kuziva uric acid yako, hapana zvakasiyana nezvakakosha kuziva chiziesterosi yako kana mazinga eropa glucose. Vanhu vane nhoroondo ye gout vanofanira kuva neuric acid level inogadzirwa mwedzi mitanhatu yekuona kuti inoramba iri pasi pe6.0 mg / dl. Kubaya varwere kunogona kurapa kurapwa nemishonga uye mararamiro ehupenyu kuti uchengetedze uric acid panzvimbo yakakodzera.
Sources:
Uric Acid - Ropa. MedlinePlus.
https://www.nlm.nih.gov/medlineplus/ency/article/003476.htm
NezveUric Acid. Gout & Uric Acid Education Society.
http://gouteducation.org/patient/what-is-gout/uric-acid/
Kelley's Textbook yeRheumatology. Ninth edition. Elsevier. Chitsauko 94: Etiology uye Pathogenesis yeHyperuricemia uye Gout.
Purine uye Pyrimidine Metabolism. Kusiyana.
https://www.diffen.com/difference/Purines_vs_Pyrimidines