Uric acid , chinhu chinowanzoitwa tsvina, ndiyo mugumo we purine metabolism. Purines ndeyemakemikari anowanzozvarwa-siyana anowanikwa mumitumbi yedu uye mukudya kwedu. Kazhinji, uric acid inoputika muropa inoshandiswa kuburikidza neitsvo uye inobviswa kubva mumuviri mumurini. Mamiriro ezvinhu, anozivikanwa se hyperuricemia (high uric acid muropa), anogona kuitika kana paine kuderera kweganda re uric acid kana kubva pakuwedzera kwekuita uric acid.
Hyperuricemia inogonawo kuguma nekubatanidzwa kwepasi-pasi uye kuwedzera kweproduction. Pasi-excretion mabhadharo ehuwandu hwemhosva dzehutachiona. Kunyanya kudyidzana kunokonzera nhamba shomanana yehutachiona hwehutachiona. Kuwandisa kwemaitiro (pasina zviratidzo) hyperuricemia muhuwandu hwevanhu inofungidzirwa kuva pakati pe2% uye 13%.
Inenge zvikamu zviviri kubva muzvitatu zvehutano huriki (urric acid) inobudiswa nokusingaperi (mukati memuviri), asi imwe yechitatu inosara inoratidzwa ne metabolism ye purines yezvokudya. Inenge 70% yeurate yakabudiswa zuva rega rega inoderedzwa neitsvo, pamwe chete nemasara anotswa nematumbu.
Uric Acid Blood Test
Izvo zvinowanzoenderana neutric acid test test iri pakati pe3,5 uye 7.2 mg / dL. Iwe unofanirwa kuziva kuti ma laboratori akasiyana angave ane zvinyorwa zvakasiyana-siyana zvemashoko. Hyperuricemia, kunyanya, inotsanangurwa sewe uric acid yeropa yepamusoro inopfuura 7mg / dL yevarume uye inopfuura 6mg / dL yevakadzi.
Uric Acid Crystal Formation
Kunyange zvazvo hyperuricemia pachayo isiri chirwere, uye mune zvimwe zviitiko zvinokonzera kusava nematambudziko, chirwere chenguva refu chehutachiona chinogona kutungamirira kukura kwekristasi. Ndiyo uric acid makristasi anobatanidzwa ne gout. Asi, kunyange nokuziva izvozvo, sangano iri pakati pehutachiona uye gout haritonzwisisi zvachose.
Varwere vakawanda vane hyperuricemia havasi kuwedzera gout - uye vamwe varwere vane zvirwere zvinogara vachirwisa zvinowanzoitika kana zvakaderera ropa uric acid mazinga. Chechi bedzi chikamu chevanhu vane hyperuricemia zvirokwazvo vanoenderera mberi kukura gout.
Uric acid makriststals, kana akaiswa muzvibatanidza, zvinogona kukonzera marwadzo akabatana, kubatana kwekubatana, kubatana kwakanyatsobatana, kubatana kwekubatana, uye kukwana kwemafambiro. Kana gout inokura, American College of Rheumatology mirayiridzo pamusoro pehutungamiri we gout (2012) inokurudzira kuti uric acid maitiro achengetwe pane imwe nhamba iri pasi pe 6 mg / dL kudzivirira gout rinoramba richirwisa.
Uric acid makristasi anogonawo kuiswa muitsvo. Uric acid makriststin muitsvo inogona kuita kuti mainyo emabwe aumbe uye anogona kutungamirira kune chirwere chepfungwa kana kushaya mafungiro.
Njodzi Zviitiko Zvinosangana neHyperuricemia
Hyperuricemia inobatanidza nehuwandu hunokonzera njodzi, dzakadai seDysglycemia (chirwere cheshuga yeropa), dyslipidemia (zvinetso zvepidid), kuneta, uye kusava nesimba kweropa - pamwe chete inozivikanwa semagadzirirwo emagetsi. Hyperuricemia inogona kukonzerwa nemararamiro asina kunaka, kunyanya, kudya kwakashata kwakanyanya mu purines, mapuroteni, doro, uye makhahydrates.
Kunyange zvazvo zvakakosha kubhadhara kutaridzika kwezvinhu zvinokonzera njodzi, zvakadai sekudya uye mararamiro, izvo chete ndezvisingakwanisi kudzora huwandu hwehutachiona.
Zvinokoshawo kuti mamwe mishonga inogona kuwedzera ngozi yehutachiona, kusanganisira thiazides, loop diuretics, uye aspirin yakaderera.
The Bottom Line
Nguva yakareba ye hyperuricemia, kana chirwere chisingaperi chine utachiona, inobatanidzwa nehuwandu hwekuwedzera gout. Kuchengetedza Crystal ndiyo migumisiro yehutachiona hwemhuka inogona kukonzera kugout kana chirwere chepfungwa. Kuchengetedza ropa uric acid pasi pasi 6 mg / dL inokosha kuti vanhu vaongorwe vane gout kudzivirira kudzivisa kurwisa.
> Sources:
> Uric Acid - Ropa. MedlinePlus. 4/29/2013.
> Chronic Hyperuricemia, Uric Acid Deposit, uye Cardiovascular Risk. Grassi D. et al. Current Pharmaceutical Design. April 2013.
> Gout uye Hyperuricemia. National Kidney Foundation.