Tinoziva kuti kudzvinyirira hakusi zvakanaka kwatiri, kunyanya zuva-mu, zuva-out-kuponeswa-mamiriro ekumanikidza anoramba kwevhiki, mwedzi, uye makore, iyo inozivikanwawo sekusingaperi mupfungwa mupfungwa. Asi zvinogona here kuva nezvakawanda zvakatibatsira kwatiri? Zvakakwana zvekukanganisa kuwedzera mungozi wezvirwere zvakanyanya uye kunyange kanzura? Mhinduro yacho inoratidzika kuva hongu kune dzimwe zvirwere, asi haisi nguva dzose mhinduro yakajeka kana iri pamusoro pekenza uye kubudirira kwayo.
Migumisiro yepfungwa dzepfungwa
Nepo kushungurudzika kwakanyanya kushushikana kwakasimba kunoita kuti tive nekukurudzirwa uye kunotidzivirira kubva pakugunun'una, kune rumwe rudzi rwekunetseka kunoita kunge rwakanyanya kuipa.
Maererano neNational Cancer Institute (NCI), kushungurudzika kwepfungwa ndizvo izvo vanhu vanonzwa kana vari pasi pepfungwa, mumuviri, kana mupfungwa. Uye kune uchapupu hwekuti vanhu vane huwandu hwepfungwa dzepfungwa mupfungwa dzavo, kana avo vanowanzosangana nematambudziko nguva refu, vanogona kunge vari pangozi yekuvandudza zvinetso zveutano zvakasiyana-siyana, kusanganisira chirwere. Zvisinei, pamwe nekuremekedza kenza, kune dzakawanda zvisingazivikanwi.
Migumisiro yebasa rekutambudzika
Boka revatsvakurudzi veYunivhesiti reMontreal muCanada vakataura nezvehukama pakati pekuonekwa kwebasa repfungwa mupfungwa uye kenza. Vanotarisa kuongorora ukama huri pakati pehupenyu hunokonzera kushushikana pamusoro pebasa rose remakore, uye kukura kwekenza-chimwe chinhu chisati chaitwa kare.
Zvitsva zvaive zvakaoma, kunyange zvazvo chidzidzo chacho chisina kugadzirirwa kubvumira chero zvipi zvaro zvakasimba pamusoro pechikonzero nemigumisiro.
Nokuda kwekudzidza, vatsvakurudzi vakabvunzurudza varume 3103 avo vakaonekwa kuti vane imwe yevane 11 mhando dzekenza pakati pe1979 ne1985. Mune rimwe boka, vakange vabvunzurudza kubva kune varume 512 muhuwandu hwevanhu avo vakashanda sekudzidzira kwekudzidza.
Vose vevarume vakabatanidzwa pakudzidza vakabvunzwa kutsanangura basa rimwe nerimwe ravakashanda munguva yavo yeupenyu, vaine hanya nebasa rinokonzerwa nebasa uye chikonzero nei vaifungidzirwa kushanda. Mutevedzeri murume ari muchidzidzo akabata mabasa mana panguva yebasa rake, asi vamwe vatori vechikamu vakatora kusvika kune gumi nevaviri kana mamwe mabasa.
Iwe Chero Zvidzidzo Zvesangano Link Career Kushungurudzika kune Kansa?
Kuratidzirwa kwenguva refu kudzvinyirira kubasa kwakabatanidzana nemikana yakawanda yekenza pa5 kubva pa11 yekenza nzvimbo. Basa mune rimwe basa rakaoma rinopindirana nemukana wakawedzera wekuve nekenza yemapapu, colon, chikafu, rectum, dumbu, uye kwete Hodgkin lymphoma .
Vatsvakurudzi vakabvuma kuti zvidzidzo zvisingakwanisi, zvakadai sokupfuura-kuzivisa kushungurudzika kune avo vaive nekenza, asi vakaramba vachiti kana zvibatanidza izvi zvakagadziriswa, vangazopedzisira vawana zvimwe zvinhu zvinokosha kuti vafambise sayenzi nemishonga.
Bhuku racho rakadana kuti vaongorore zvidzidzo kuti vaongorore mubvunzo uyu uchiwedzera-mune mamwe mazwi, vanotaura nezvekudiwa kwezvidzidzo zvinotanga neboka revanhu vane utano, kunyatsoyera kushaya dambudziko nenzira yakarongeka, uye shure kwekufamba kwenguva kuongorora kanha kukura , kufunga zvose zvakasiyana-siyana zvinokonzera kushungurudzika uye kuchinja pamusoro pepanguva yebasa, uye kutarisa kune zvimwe zvinoshandiswa sezvinogona.
Icho chirefu chakareba.
Vamwe vanotora pfungwa pamusoro pemabasa anoshungurudza:
- Mabasa anonyanya kunetseka aisanganisira kupisa moto, injini yezvinjiniya, injini yekugadzira ndege, mumiririri wemagetsi, uye motokari uye gorosi-kugadzirisa magetsi.
- Pfungwa dzinoonekwa dzakabatana nemabasa dzimwe nguva dzakasiyana zvichienderana nebasa rakaitwa.
- Kushungurudzika kwairehwa ne "basa rakakura uye nguva yakamanikidzwa, asiwo kubasa revatengi, kutengesa mabhizimisi, mabasa, zvemari, kusagadzikana kwebasa, mamiriro ezvinhu anokuvadza , kutarisirwa nevashandi, kurwisana kwevanhu, uye kuoma kwakaoma."
A Tarisa Biology
Kushungurudzika kunokanganisa sei muviri?
Yeuka, kushungurudzika mupfungwa kunoumba muviri, mupfungwa, kana mupfungwa. Kana iwe uchifungidzira vanhu vasati vamboitika vachiedza kupona panyika ino, unowana pfungwa yekuti kushungurudzika kunotitungamirira sei muupenyu hwedu hwezuva nezuva. Mitumbi yedu inosunungura mahomoni ekudzvinyirira akadai se epinephrine uye norepinephrin iyo inotitadzisa kuva takangwarira kune zvakapoteredza uye kutarisana nekuongororwa kwakaoma kwekutyisidzira kupfuura zvatinogona kuita, taura paunenge uchiraira kuti urove kana kuenda kunorara . Aya mahomoni anowedzera kukanda kweropa, kukurumidza kwema moyo, uye kusimudzira mashizha eropa redu kuitira kuti tikwanise kudana simba redu rose, nekukurumidza, uye kukurumidza kutiza chero zvingave zvingave.
Vatsvakurudzi vakabudisa zvidzidzo zvinobatanidza nguva refu, kusingaperi kushungurudzika kumarudzi ose emamiriro akasiyana-siyana, kusanganisira zvinetso zvekudya, zvinetso zvekuberekwa, zvinetso zvekuvhota, uye utachiona hutachiona hwakaoma . Kushungurudzika kwakadaro kunoratidzika kuderedza kudzivirirwa kwedu-haisi pangozi iyo vanhu vanowanzouya nehove inotungamirira kune chimwe chinhu chinokosha, kunyanya kana chiitiko ichocho chiri kuita kuti vawedzere kushungurudzika uye kuzvidya mwoyo.
Maererano neCNI, vanhu vanoona kusagadzikana kusingaperi vanowanzoita zvirwere zvinokonzerwa nehutachiona hwehutachiona kana hutano husati huripo uye kuva nemusoro, kushaya dambudziko, kuora mwoyo, nekuzvidya mwoyo. Uyewo maererano neCNI, zvakadaro, "nyaya" yekudzvinyirira sechikonzero chinokosha chekenza, ikozvino, haisi yakasimba. Kune zvimwe zvidzidzo zvinoratidza kubatana pakati pepfungwa dzakasiyana-siyana uye nekukura kwekenza, asi zvimwe zvidzidzo hazviratidzi izvi.
Ndezvipi zvinogona kufungidzira zvinyorwa zvinokonzera ngozi yechirwere? Rimwe boka revanotsvakurudza rinofarira kuti kushungurudzika kunogona kuita sei kuti vanhu vaite maitiro asina kunaka sekusvuta, kudya uye kunwa kudarika, kana kunwa doro. Mumuenzaniso uyu, ndiyo inonyanya kuipa mafambiro anowedzera huwandu hwemunhu wekenza. Imwe misasa inofarira maitiro ehupenyu hwehupenyu husingaperi, iwe pachako, uye kubatana nekukura kwekenza uye kubudirira. Kambani imwe neimwe inobvuma kuti nzira mbiri idzi dzinogona kunge dzichitamba mumunhu mumwe chete.
Kushungurudzika uye Kubatana Kwaro neRopa Cancers
Dzimwe tsvakurudzo dzakaona kuti zvinhu zvinokonzera kufunganya zvinobatanidza nekufambira mberi kwakakurumidza kwemhando dzakasiyana-siyana dzekenza, kusanganisira ropa rekenza sereukemia uye lymphoma . Kana zvasvika kune ngozi yakawanda yekudzidzira kanzura nekuda kwekutambudzika, zvigumisiro zveongororo zvakave zvisina kufanana, maererano nevanyori vepepa rakabudiswa mumagazini yaNovember-December 2011 ye "Psychosomatic Medicine."
Izvi uye zvimwe zvidzidzo, zvisinei, zvakaratidza humwe uchapupu husingagumi kuritsigira pfungwa yokuti zvinhu zvakadai sekutambudzika, kuora mwoyo, uye kusurukirwa kwevanhu vanogona kuva nemigumisiro yezinga iro kenza inofambira mberi , uye izvi zvinonetsa zvinosanganiswa nekufambira mberi kwekenza nokukurumidza.
Kana iwe uchienda kune zvidzidzo zvemhuka, kune zviwanikwa zvinoita kuti munhu afunge kufungidzira kana kusagadzikana kusingaperi kunogona kutungamirira kukurudzirwa nekufambira mberi kweimwe marariya. Rimwe boka revanotsvakurudza rakasarudza kudzidza rudzi rweroukemia-pre-B ALL-vachishandisa mhando yemagetsi. Mune vanhu, chirwere chinokonzerwa neukemia chinowanikwa mumarudzi mana ezvinyorwa zvinotarisana nemasikirini nemaperembudzi nemirwere yakakura. Pamakumbo mana, acute lymphoblastic leukemia (ALL) ndiyo inonyanya kurudzi rwekenza muvana vaduku , uye pre-B cell ALL ndiyo inonyanyooneka yakasiyana-siyana yeukemia mune vana nevechiri kuyaruka.
Zviwanikwa kubva kuongororo dzakagadzirwa pamakonzo dzine tsika inonyadzisa yekusava kushanda kune vanhu, uye saka tiri iye zvino munharaunda yedzidziso yakachena yesayenzi. I-B-B ALL Mouse Yokudzidza kudzidza yakanga inofadza, zvakadaro, kubva pakuona kwekuti pfungwa nemuviri zvingangodaro zvakabatana sei, uye kuti izvi zvinosanganiswa sei zvingashanda kune kenza yeropa.
Vatsvakurudzi vakaona kuti kune mishonga inobatanidza nekunetseka kwepfungwa iyo inogona kuratidza fufupa remapfupa, iyo inzvimbo yega yese yesero yekuumbwa. Kunyange zvazvo zviratidzo izvi zvinotendwa zvinotendwa kuti zviite masero ezvisikwa (asina kenza) masopa-forming cells (hematopoietic progenitor cells), boka iri rekutsvakurudza rakashamisika kana kushungurudzika kungaita kuti mitsetse iyi ishumire bone marrow nenzira iyo, inopfuura nguva, inogona kuchinjawo kufambira mberi kweAIDS yose yeukemia.
Vatsvakurudzi vakaita mhando dzekutanga dzeB B dzose dzingangopenya, kuitira kuti dzigone kuongororwa kana dzichiendeswa mumashani e laboratori. Vakaona kuti kushungurudzika kusingaperi kunogona kukurumidza kufambira mberi kwehupenyu hwevanhu B pre-B ALL tumor kuburikidza nemugwagwa-chiratidzo chekuita. Vaifungidzira kuti kukanganisa kwakadaro pamusoro peBHB yose yekenza kwakanga kusinganzwisisi, asi kuburikidza nedzimwewo, dzisina kenza, masero emunharaunda munzvimbo, zvakadai semasero ezvirwere kana mamwe masero mumutsetse wemafuta.
Kurarama Nekenza uye Kukurira Kushungurudzika
Mubvunzo wekugadzirisa kushushikana nekuuya pakusangana nechirwere chinopisa upenyu chinhu chakakomba, uye chimwe chisingagoni kutarisirwa nenzira yakakwana mumutambo uno. Zvisinei, kana iwe une kenza, vanhu vazhinji vari muhomwe dzako vakati vakabatsirwa nekenza yekenza, rubatsiro rwemagariro muboka, nguva dzose yekurovedza muviri, kupa mazano kana kutaura, pamwe nemishonga yekuora mwoyo uye kuzvidya mwoyo.
Maererano neNational Cancer Institute, kugadzirisa kushandiswa kwemafungiro nemaitiro ekugadzirisa kuhupenyu huripo, uye sangano rinotaura kuti vanhu vanotarisana nenzira dzakasiyana. Kutarisana nemunhu kunowanzobatana nehupenyu hwavo.
Zvakakoshawo kuziva kuti kugadzirisa kunogona kuenzana nebasa idzva-nguva, yemhando. Zvipe iwe nguva yekuzvipira, uye uzive kuti izvo zvinoda basa zvinogona kutenderera mukati mezvikamu zvakasiyana-siyana sezvaunosvika munzvimbo itsva mumugwagwa wako wekenza. Ikoko kunogona kunge yakasiyana nemanzwiro anouya nenharaunda pane imwe neimwe yezvikamu zvinotevera, somuenzaniso: kuonekwa, kurapwa, kusvika pakuguma kwemishonga, kuva mukuregererwa, nekudzidza kenza yakadzoka.
Pamubvunzo wekuora mwoyo mukati mekenza, American Society of Clinical Oncology inokurudzira kuti murwere wese ane kenza anongororwa kuora mwoyo apo kuongororwa kwekenza kunotanga kuitwa, uye nguva dzose, kunyanya pamatanho makuru kana nguva dzekuchinja mumunhu chirwere.
Dzimwe nguva zvinogona kuva zvakaoma kuziva kutambudzika mune mumwe munhu ane kenza. Somuenzaniso, kunzwa sezvakaita iwe mutoro kune vamwe pfungwa yakawanda inogona kuitika panguva imwe kana imwe kana ichibata nemamiriro ako. Hazvirevi nguva dzose kuti iwe wakaora mwoyo, asi kunzwa uine mhosva zvakanyanya pamusoro pazvo kungava chiratidzo chekuora mwoyo. Unonzwa usina tariro kuti iwe uchaporeswa iwe wava pedyo nekufa nderimwe mamiriro ekufunga, asi usina tariro, mune dzimwe nzvimbo-hapana tariro yokuti iwe unogona kuchengetedzeka, kana kuti hapana tariro yokuti vana vako vacharamba vachibudirira mu upenyu hwavo mushure mokuchema kurasikirwa kwako-izvi zvinogona kuva zviratidzo zvekuora mwoyo.
Shoko Rinobva
Vanhu vanoshandisa shoko rokuti "muparadzi wekenza" nenzira dzakasiyana. Vamwe vanopukunyuka kenza vanoziva kuti kenza ichapedzisira ichitora hupenyu hwavo, asi vamwe vakaporeswa uye vanogona kutarisira kurarama hupenyu hwakakwana. Mune zvimwe zviitiko, vapukunyuka vanongogara vachinjwa kubva pane zvakaitika.
Nguva yemberi ichazoenderera mberi kuzarura zvikamu zvitsva zvehukama pakati pemafungiro nemuviri mukurapa uye kunyanya munharaunda yekenza. Kubva ikozvino, kugadzirisa kushushikana zvakanakisisa sekunge iwe unogona kubatsira pakurarama unhu hwepamusoro hwehupenyu.
> Sources:
> Blanc-Lapierrea A, Rousseau MC, Weiss D, et al. Mushumo weupenyu hwose wekunzwisisa kunetseka kubasa uye nekenza pakati pevarume: A-control control study muMontreal, Canada. Prev Med. 2016 Dec 5; 96: 28-35. doi: 10.1016 / j.ypmed.2016.12.004. [Epub mberi kwekudhinda].
> National Cancer Institute. Psychological Stress and Cancer. https://www.cancer.gov/about-cancer/coping/feelings/stress-fact-sheet.
> Lamkin DM, Sloan EK, Patel AJ, et al. Kushungurudzika kwenguva refu kunowedzera kukura kweacute lymphoblastic leukemia kuburikidza ne β-adrenergic chiratidzo. Ubongo Behav Immun . 2012; 26 (4): 635-641.