Melatonin muCcercer Prevention and Treatment

Kunyange zvazvo melatonin ihomoni inokonzerwa neuropi, unogona kuzviziva zviri nani sewe-rem-counter remedy for jet lag uye kuvhiringidzika kwehope. Uropi hwepineal gland unovanza melatonin mumaawa makumi maviri nemaviri. Iyo inobudiswa zvakare muganda, retina yeziso uye mapfupa emapfupa.

Muzvisikwa, kubudiswa kwemasvikiti e melatonin panguva yeusiku, uye inodziviswa nechiedza chezuva.

Uye rima rinouya kuwedzera mazinga e melatonin, kuunza kushaya simba uye kugadzikana-uye netariro, kurara. Zvimwe zvinhu uye mahomoni zvakadai sa serotonin anokosha zvakare, zvisinei, mukuraira kurara kwemuviri kurara .

Kurara, Melatonin uye Cancer

Zvidzidzo zvinoratidza kuwirirana pakati pekurara kwekurara, hutsika hwema melatonin uye kenza zvinokurudzira zvakanyanya kufarira. Basa rekushanduka kweusiku rinosanganiswa nekuneta uye kusuruvara, mazinga akaderera e melatonin muropa, uye zvirwere zvakasiyana zvakasiyana-siyana zvinosanganisira chirwere chemwoyo, chirwere chemagetsi-uye kanzira dzemhando dzakasiyana-siyana.

Shift Work and Risk Risk

Zvose izvi zvakawanikwa nevashandi vanotsinhanisa vakatungamirira mamwe masayendisiti kushamisika kana melatonin inogona kubatsira kudzivirira vanhu kubva pazvirwere izvi. Imwe kuongorora kweCanada muvarume vevashandi vanoona kuti usiku huno basa raibatanidza nehuwandu hwemhando dzakasiyana dzekenza, kusanganisira kwete Hodgkin lymphoma .

Izvozvi zvidzidzo zvinotarisa kuona kuti chinhu chinowanzosanganiswa chinopindirana nechimwe chinhu-ivo "chikamu chepakati," kana izvo zvinonzi zvinopararira mune zvakasikwa.

Dhiyabhorosi kubva kuongorori dzakafanana inoratidzika kuti inobatsira pane zvinogona kuitwa ne melatonin uye kuvhiringidza kurara mucheche rehadzi zvakare: vakadzi vanoshanda usiku hwekuchinja vane 19 kusvika ku 51 muzana vakawedzera ngozi yekenza yemazamu. Nezvekenza yeprostate , imwe yongororo yakawana kuti varume vane kenza yeprostate vaiva nemaodzanyemba e-melatonin akaenzaniswa nevarume vakanga vasina avo vane kenza asi vanogona kurara-kuora mwoyo, benign prostatic hyperplasia.

Hapana chimwe chezviongorori izvi ndeyomufananidzo unogona kuratidza chikonzero nemagariro, zvisinei. Zvitsva zvinoshandiswa kuwedzera zvidzidzo zvekare, asi hazvirevi kuti zvinotsigira kushandiswa kwe melatonin kudzivirira kenza.

Zvinyorwa zveMhuka neBrazil

Zvidzidzo zvebhakirini zvinoratidza kuti melatonin inorwisa antioxidant iyo inokurudzirawo dzimwe nhengo dzomuviri wechirwere chemuviri, asi hazvizivikanwe kana izvi zvichiitika kuvanhu. Melatonin inoratidzika inodzivisa mamwe kenza yemukenza kuti irege kukura iyo inoshandiswa zvakananga kune idzi masero mu laboratori ndiro uye mune zvidzidzo zvemhuka-izvi zvakaratidzwa mukenza yemazamu uye melanoma.

Zvidzidzo muvanhu, zvisinei, hazvirevi kuti chero chii zvacho chinonzi antiticancer.

Kubva pane in vitro data, mamwe masayendisiti ave achifunga kuti kudzivirira muviri, kana zviripo mu vivo, zvingasava chinhu chakanaka mumatambudziko ose. Semuenzaniso, zvakaipa zvisina kunaka zvekudzivirira zvirwere mumuviri kune varwere vane leukemia kana lymphoma zvingangove zvisingabatsiri, sezvo aya kanzira inosanganisira kuipa kwemasero omumunikirini mu lymph system, bone marrow neropa.

Melatonin muzvirongwa zvekuenzanisa akaratidza zvimwe zvirwere zvinopesana nekenza, uye kukurudzira kwemuviri wesimba kunofungidzirwa kuti inobatanidzwa. Chidzidzo chaMiller chakaratidza kuti melatonin inobatanidzwa mukushandiswa kwe lymphocytes uye monocytes / macrophages-marudzi akasiyana emasero machena eropa.

Lymphomas ndiwo marariya anokonzerwa ne-lymphocytes.

In vitro, melatonin inoratidzika kuita mukuwedzera kwemuurayi wepanyama T-cell basa , kukurudzira mamwe majekiseni esero anonzi cytokines; inogonawo kuchengetedza mamwe masero epachiviri chechiropa kubva kune chepfu inokonzera chemotherapy uye radiotherapy , maererano nechidzidzo che2001 chaMaestroni.

Zvakare, hazvizivikanwe kana ma melatonin angave nemigumisiro iyi mu vivo, muvarwere chaivo.

Melatonin muCcercer Treatment

Zvishoma zvishoma zvinonyatsozivikanwa pamusoro pe melatonin kana zvichishandiswa kuvanhu vane kenza. Rimwe boka revasayendisiti rakarongeka kuongorora migumisiro ye melatonin apo yakapiwa pamwe nekemotherapy, radiotherapy, kuchengetedza, uye kurapa kwepamusoro kune varwere vane mastradio yakasimba - kwete leukemia kana lymphoma.

Muchidzidzo ichi, melatonin haina kubatanidzwa nehuwandu hwehutachiona kana kuderedza kushandiswa kwehutano, uye yakaratidzika kubatsira kune dzimwe chemotherapy nemigumisiro.

Melatonin muRopa Cancer Patients

Kunyange zvakadzama zvinozivikanwa kana zvinosvika kune melatonin kune vanhu vane kansa yeropa seyeukemia uye lymphoma . Iye zvino National National Comprehensive Cancer Network (NCCN) mazano pamusoro pezvisiri zveHodgkin lymphomas, iyo yakakurumbira yemhando ye lymphoma, haisanganisi mazano pamusoro pemashandisirwo e-melatonin.

Chizhinji chekutsvakurudza kwakabudiswa ikozvino pamusoro pe melatonin iyo inenge yakabatana ne lymphoma inoratidzika inobva mune in vitro uye yemhuka data, kwete makiriniki.

Nguva dzose taura nachiremba wako nezvekutora chero chekuwedzera, sezvo zvidimbu zvinogona kuve nemigumisiro yakaipa uye kusangana kwemishonga.

Shoko kubva kune:

Melatonin yakashandiswa zvakachengeteka sehope yekubatsira kwevakawanda, uye ine basa rakagadziriswa mukurapa kwekuvhiringidza kwakasiyana-siyana kwehope.

Melatonin chigadzirwa chechisikigo, asi michina yakasikwa inogona kuva nemigumisiro yechirwere uye kusataurirana kusingatarisirwi. Melatonin inogona kusangana nemhando dzakasiyana-siyana dzemishonga, kusanganisira sedative, antidepressants, mishonga yehomoni, nezvimwe.

Taura nachiremba wako pamusoro pekushandisa kwako melatonin kana chimwe chekuwedzera-kunyanya kana uri kurapwa nekenza kana chero humwe hutachiona husingaperi.

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NCCN Mirayiridzo yeChino-Hodgkin Lymphoma. Version 1.2016. Yakasvika muna February 2016.