Lymphoma ikenza yeropa inokanganisa lymphocytes, rudzi rwechichena cheropa. Mhando mbiri dzakakura dze lymphoma ndiHodgkin's lymphoma uye isiri Hodgkin's lymphoma, kana NHL. Kunyange zvazvo lymphomas inowanzotanga mumakirinikodhi , inogona kumuka chero kupi zvako mumuviri. Apo pavanomuka kunze kwemaitiro emakirini, vanonzi extranodal lymphomas.
Primary bone lymphoma inowanzoshandiswa extranodal lymphoma . Apo lymphoma inotanga kunze kweropa nhengo dzomukati, zvinowanzova zvakajairika kuti chirwere chinotanga kubuda mumutsara wepamuviri kupfuura mune pfupa.
Overview
Primary bone lymphoma inonyanya kukosha iyo iyo lymphoma inotanga mumapfupa. Ichi chiitiko chinokonzera 1 kusvika 2 muzana yezviitiko zvose zvisiri zveHodgkin lymphoma , ine zvikamu zvakakwirira zve 3 kusvika ku 9 muzana muvana nevechiri kuyaruka. Cancers inotanga kune imwe nzvimbo uye inozopararira kumapfupa yakawanda zvikuru kupfuura primary bone lymphoma.
Ndiani Anobatwa ?
Primary bone lymphomas inonyanya kubata vanhu vakuru. Vanhurume vanowanzove vakanganiswa kupfuura vakadzi. Vakawanda havasi Hodgkin lymphomas yeB-cell , iyo iyo nhamba yepamusoro inokwira iri pakati pemakore makumi mashanu nemakumi matanhatu. Zvisinei, kana inosvika pasi pepamusoro pa sacrum kana tailbone, primary bone lymphoma ine peji chiitiko mumakore gumi nemaviri.
Uye zviitiko zvisingawanzoitiki zvinoitika kune vana vane makore ane makore gumi nemaviri.
Zviratidzo
Vanhu vazhinji vanobatwa nepakutanga bone lymphoma vanotanga kurwadziwa mumapfupa avo. Kazhinji kurwadziwa kunonzwika kunyange pazororo. Izvi zvinogona kuramba kwemwedzi zvisati zvaitika zvimwe zviratidzo zvinomuka. Apo lymphoma inokura yakakura, inogona kukonzera kupfupa kwechimiro uye kupedza kukama kwemaoko kana gumbo.
Zvimwe zviratidzo zveLymphoma zvakadai sefivha uye kuora kurasika hazviwanzoitiki.
Miedzo
Kuona kufungidzira, X-rays, uye zvikamu zvepfupa , anobatsira kuona chetatu bone lymphoma. Chirwere chepfupa chinoratidza kuchinja kwechimiro muchitarisiko chefupa paMRI kana CT scans. Ikoko kunogona kuva kudyiwa kwechifusi nzira yekuparadzwa kwemapfupa munzvimbo dzakakonzerwa ne lymphoma.
Kuti uone rudzi rwemarara, biopsy yemapfupa yakaitwa. Izvi zvinogona kuitwa chirwere, nekutora chiduku chiduku chechirwere-chakabatanidza bone rekuongorora kukuru. Mimwe miedzo inobatsira kuziva kana chirwere chacho chakapararira kana kukwana pfupa. PET / CT yemapfupa, mimba nemapapu zvinogona kushandiswa kutarisa kuwanda kweropa rekuvhara muviri uye kuvapo kwezvirwere zvakakura.
Aina
Kazhinji kazhinji, primary bone lymphoma haisi Hodgkin lymphoma kana NHL. Hodgkin lymphoma yemapfupa hazviwanzoitiki. Pakati pemarudzi akasiyana-siyana eNHL, anoparadzira B-cell lymphoma yakakura kana DLBCL, ndiyo inowanzoshandiswa pfupa rinonzi bone lymphoma. Rudzi rwe lymphoma mirayiridzo pamusoro pemhando yekurapa inogona kutevedzwa.
Kurapa
Nemhaka yekuti primary bone lymphoma haigoneki, rimwe chete remakirini ehurumende risiri rakatadza kuitwa. Mishonga yemazuva ano inowanzomirira chemotherapy kune zvishoma zvishoma pamwe chete neradio therapy kumapfupa.
Kurapa pamhando dzakasiyana dzakasiyana-siyana, kana kuti kurapa kwema-multimodal, kwakajairika, zvisinei, kugoverana kwemayera uye chemotherapy kunowanika mumishumo yakabudiswa. Kuponeswa kwemitambo yepakutanga bone lymphomas kunowanzova nani kune mamwe maitiro easiri Hodgkin lymphoma.
Yunivhesiti yeMiami inoti inopfuura 80 kubva muzana yevanhu vanobatwa nepamusoro pepfupa lymphoma vasina kuwedzera kwechirwere chavo makore mana gare gare - vakawana 83 kubva muzana-kufambira pasina, kana PFS mukuongorora 53 varwere. Hapana misiyano yakaonekwa pakati pevarwere vanobatwa nekemotherapy kana kuti vakabatanidzwa chemotherapy pamwe nemirairo.
Zvisinei, paiva nechinangwa chekuvandudzwa kwePPS kune varwere vane DLBCL vanorapwa ne rituximab pamwe chemotherapy.
Mhedziso
Mushure mokurapa, PET / CT magero anogona kunyanya kubatsira kuongorora kupindura kwerapi. Iko mushure mokurapa kufungidzira kufungidzira kwesarudzo ndeye PET / CT scan, iyo inobatsira kusiyanisa zvirwere zvinoramba zvichibva kune fibrosis. Varwere vanofanira kuongororwawo kwenguva refu. Bone lymphoma ine uwandu hwakaderera hwekudzoka kwekune dzimwe nzvimbo uye kakawanda inodzokera kune nzvimbo dziri kure kubva kuchirwere chokutanga.
Sources
Kuti uwane zvakawanda pamusoro pechinyorwa chino, tsvaga zvinotevera:
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Thornton E, Krajewski KM, O'Regan KN uye al. Kufungidzira zvikamu zvekutanga uye zvechipiri zvinouraya zvipembenene zve sacrum. The British Journal of Radiology . 2012; 85 (1011): 279-284.
Kufananidza kwePfu Zvirwere uye Mhemberero-Sezvipfeko: Maitiro uye Applications; A. Mark Davies, Murali Sundaram, Steven J. James. Springer Science & Business Media, 2009.
Nheyo uye Maitiro Ehutsvaji Oncology 4th Ed. Vatori: Carlos A Perez, Luther W Brady, Edward C Halperin, uye Rupert K Schmidt-Ullrich. Lippincott Williams & Wilkins, 2003.
Chinyorwa K, Allen L, Yahalom J. Primary Bone Lymphoma: Zvigadzirwa zvekurapa uye zvirevo zvekufananidzira nekutsvaga kwenguva refu kwevateereri 82. Cancer , 2006; 106 (12).
O'Connor AR, Birchall JD, O'Connor SR et al. Ikoshi ye 99mTc-MDP bone scintigraphy mu staging primary lymphoma yemapfupa. Nuclear Medicine Communications. 2007; 28 (7): 529-31.
Swerdlow SH, Campo E, Harris NL, et al, eds. Nzira yeAIDS yeHummy yeHaematopoietic uye Lymphoid Tissues. 4th ed. Geneva, Switzerland: IARC Press; 2008.