Ropa Kansa Pasi Pamu Microscope

Imwe nzira yekare yekufungidzira kwechiremba achiri kushandiswa nhasi - microscopy chiedza. Kana zvasvika pakutsvaga mhando chaiyo yekenza, kana sarudzo yekudzokazve, masayendisiti akafara chaizvo akawedzera zvigadzirwa zvakawanda kubva panguva iyo microscope chiedza yakagadzirwa, kusanganisira kuonekwa kwemuviri mukufungidzira kwezvokurapa uye kuongororwa kwebiologic marker muropa .

Kunyange zvakadaro, kutaridzika kwemaitiro maswere kunyange nhasi kunowanzoita basa rinokosha pakutsvaga uye kuenzaniswa kwe- eukemia uye lymphoma uye inogona kuva chikonzero pakusarudza gorosi kana kushungurudzika kwechirwere chakaipa. Kunyange zvazvo vanachiremba vemazuva ano vanowanzotarisa makondombera pahutano hwemajeni avo ega uye kuchinja, dzimwe nguva mufananidzo unenge uchikwanisa mazwi ane chiuru. Heano mifananidzo mishomanana inoratidzira maonero mashoma emhando yemukemukemia, rudzi rwe lymphoma uye muchengeti T inoshandiswa kurwisa kenza yekenza.

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Hodgkin Lymphoma

Izvi zvinoratidza nyaya yeHodgkin lymphoma, dzimwe nguva inonzi Hodgkin chirwere. Hodgkin chirwere chinogona kuitika kune vose nevakuru, zvisinei, makore ekukwegura ari mumakore makumi maviri nemakumi manomwe nemakumi manomwe nemakumi matanhatu. Muchiitiko ichi, haisi ropa remurwere iro rave richionekwa pasi pe microscope; pane kudaro, chikamu kana kuti chikamu kuburikidza ne lymph node inobatwa nechirwere cheHodgkin-kenza yemavhenekera eropa kana lymphoma masero. Masero ebhuruu ayo ane maziso ewuchi anonzi maReded-Sternberg masero ndiwo chiratidzo chemaHodgkin lymphoma. Vanoratidzika semakungu pavanosvibiswa kuitira kuti vaonekwe, uye pano hobe mbiri dzinogona kuonekwa. IAmerican Cancer Society inofungidzira kuti anenge 9,190 mamiriro matsva eHodgkin lymphoma anoonekwa gore roga roga.

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Isingaperi Myelogenous Leukemia

Pamufananidzo wakafananidzwa wehutachiona hwemurwere hwemurwere, masero matsvuku ane bhuruu anomiririra masero eropa eropa anowedzerwa nhamba, chimwe chinhu chinowirirana nemakumbo asingakanganwiki eukemia (CML). Zvimwe zvinhu zvakawanda zvinogona kukonzera kuwanda kwepamusoro, asi CML ndiyo yakakonzera munyaya iyi. CML inogonawo kunzi chisingagumi myeloid leukemia kana chisingagumi granulocytic leukemia. CML inowanzokonzera vanhu vakwegura uye inowanzoitika kune vana. Vanhu vanogona kuva ne CML kwenguva yakareba vasingazivi. CML inosanganiswa nechimwe chinonzi Philadelphia chromosome , chromosome inowedzera-iyo inonzi zita reguta iro rakawanikwa. Vamwe 90 muzana yevanhu vane CML vane masero eropa neChristelphia chromosome. Kunenge 10 muzana chete yeeukemias ndeye CML. IAmerican Cancer Society inofungidzira kuti inenge 5,980 mitsva itsva ichaongororwa gore negore.

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Chirwere cheMusana Chemunhu Kuuraya Kenza Yekenza

Pano tinoona muurayi T cell (iri sero duku duku pasi pekenza yerineni mumufananidzo uyu) inobatana nekenza yesero. Iko chaizvoizvo shanduro yemuiti, asi yakabva pane chokwadi. Kunyora masikironi microscopes inoita mifananidzo yakafanana. Muurayi T masero anodzivirira masero ayo anogona kuuraya mamwe masero, kusanganisira masero kunze, masero emukenza uye masero ayo akawana utachiona. Maererano neNational Cancer Institute, masero anouraya T anogona kukura mu laboratori, ndokuzoendeswa kune murwere kunouraya masero emukenza. Muurayi T masero akachena masero eropa, uye kunyanya, iwo rudzi rwe lymphocyte. Muurayi T masero anogonawo kutumidzwa se cytotoxic T masero uye cytotoxic T lymphocytes.

> Sources:

> Barrett DM, Singh N, Porter DL, Grupp SA, June CH. Chimeric Antigen Receptor Therapy yeCarcer. Annu Rev Med. 2014; 65: 333-347.

> El-Galaly TC, Mylam KJ, Bogsted M, et al. Basa rekufungidzira nguva dzose pakuona kakareru lymphoma: Kuongororwa kwevamwe 258 varwere vakadzokerazve zvechisimba kwete Hodgkin neHodgkin lymphoma. Am J Hemat. 2014; 89 (6): 575-580.

> America Cancer Society. Chronic Chronic Myeloid Leukemia (CML).

> America Cancer Society. Ndezvipi zvinyorwa zvinokosha nezveHodgkin chirwere?