Ngozi nemigumisiro yeCelebrex yeigraine therapy
Celebrex - generic name celecoxib - rudzi rweussteroidal anti-inflammatory kana NSAID . Inoshanda nekudzivirira prostaglandin-induced inflammation mumuviri, nokudaro kuderedza marwadzo. Kunyange zvazvo inowanzoshandiswa kurapa arthritis , vamwe vanachiremba vanorondedzera Celebrex nokuda kwechiremera migraines.
Ko Celebrex Yakasiyana Sei Nechechi NSAID?
Celebrex inokonzera enzyme mumuviri anonzi COX-2, iyo inokonzerwa nekuputika mumuviri.
Ibuprofen uye naproxen, kune rumwe rutivi, zvinotora zvose maEymys COX-2 uye COX-1 - saka dzinonzi zvisati zvasarudza NSAIDs. COX-1 inyuchi inobatsira kuchengetedza chigadziko chemuviri uye mumatumbo.
Nepo NSAIDs dzinogona kuderedza marwadzo nekuputika nekutsvaga COX-2, zvinogona kukonzera kukuvadza kumudumbu uye mumukati mutsara, zvichiita kuti kuve nekubuda ropa uye zvironda. Nokusarudza kusarura COX-2, Celebrex inoderedza ngozi yepamu uye yepamuviri matambudziko.
Is Celebrex Inorondedzerwa Neurologists yeMigraines?
Kunyangwe zvazvo NSAID inonzi inorapwa-line yekurapa kwemagraines akaoma, zvichiri kungwarira inoshandiswa navanachiremba vakawanda mukugadzira Celebrex. Izvi zvinokonzerwa nekubviswa kweimwe COX-2 inhibitors kubva pamusika, saVixx (rofecoxib), nekuda kwekubatana kwavo nematambudziko emwoyo.
Iye zvino zvose zveNSAID, kusanganisira Celebrex, inotakura nyevero yebhokisi yehuwandu hwehutano hwehutano hwehutano hwepfungwa, sekurwadziwa kwemwoyo uye kurwara.
Izvozvo zvichiti, Celebrex inogona kuva nzira yakasiyana yekurapa mukurapwa kwemagraines akaoma, kunyanya kuvanhu vari pangozi yeNSAID-inokonzerwa kukuvara kumudumbu uye mumatumbo. Kuti titsigire chirevo ichi, chimwe chiduku chakaongororwa muna 2007 muSingapore Medical Journal chakaona kuti 400mg ye celecoxib yakanga yakaenzana ne 550mg naproxen mukuderedza migraines yakaoma-uye celecoxib yakakonzera kurwadziwa kudumbu zvishoma kupfuura naproxen.
Ndezvipi Vamwe Vanobvunza Kuti Chiremba Angaita Kuti Akubvunze?
Sezvo nemishonga ipi, zvakakosha kukurukura zvose zvinogona kuisa njodzi nemigumisiro pamwe nechiremba wako. Heano mienzaniso yemibvunzo shomanana chiremba wako angakubvunza iwe:
- Ndeipi mamwe mishonga iwe uri kutora? Mamwe mishonga inobatanidza neCelebrex kana kuti yakaipisisa simba rayo remigumisiro.
- Iwe une chirwere chipi zvacho here? Semuenzaniso, haufaniri kutora Celebrex kana uine chirwere chemafuro, mikoko, kana zvinokonzerwa neASAID munguva yakapfuura.
- Iwe une dambudziko rehutano here? Semuenzaniso, Celebrex haifaniri kupiwa mushure mekunge mushure mokunge uchinge wavhiyiwa.
- Uri nepamuviri here? Celebrex haifaniri kushandiswa mumatanho ekupedzisira ekudzivirira.
Matambudziko Akakomba Maitiro eCelebrex
Izvi zvinoda kuti uone chiremba wako pakarepo uye uise:
- Anoriginal reaction (kunetseka kufema; kuvhara kwehuro pako; kurira kwemiromo yako, rurimi, kana chiso; kana mikoko)
- Kusuruvara kwemuviri, unyoro, kana kushungurudzika
- Ropa, rima, kana kuti tarry zvigaro
- Nausea kana kuora mwoyo
- Kuruka ropa
- Kusatsanangurwa kuwedzera kuwanda
- Kuchengetedza kana kuchengetedza mvura
- Kusuwa kunoshamisa kana kutadza
- Kushanda kweganda kana kuchenesa
- Kuchengeta kweganda rako kana maziso
- "Flu-like" zviratidzo
- Kusagadzikana kusinganzwisisiki kana kubuda ropa
Nemhaka yezvingaita kuwedzerwa njodzi yekurwadziwa kwepfungwa uye kurohwa neCelebrex nedzimwe dzisiri-aspirin NSAIDs, sezvinoitwa ibuprofen uye naproxen, zvakakosha kutsvaka kurapwa pakarepo kana uine kurwadziwa kwepfupa, zvinetso kufema, utera pane rumwe rutivi kana rutivi rwe muviri, kana kutaura kusinganzwisisiki.
Zvimwe zvisingasviki zvakanyanya zvinokonzerwa nemigumisiro zvinosanganisira flatulence, diarrhea, chirungu, zviratidzo zvinotonhora. Zvakakosha kuonana nechiremba wako kana ukacherechedza mimwe migumisiro inoshungurudza, inopfuurira, kana iri pamusoro pako kana vamwe.
Izvi Zvinorevei?
Kana chiremba wako achinyora Celebrex nokuda kwemigraines yako, unogona kuiona ichikarira pamudumbu mako kupfuura Aleve (naproxen) kana Motrin (ibuprofen).
Sources
American Academy of Neurology. Zviratidzo-Kubva Mirayiridzo yeMigraine Headache muNheyo Yenheyo Yokutarisira: Pharmacological Management of Acute Attacks. Yakadzorerwa musi weChipiri 2, 2015.
FDA. FDA inobvumira zvinyorwa zvekutanga zve celecoxib. Kudzorerwa musi waDecember 2, 2014.
Hawkey CJ. COX-1 uye COX-2 inhibitors. Best Pract Res Clin Gastroenterol. 2001 Oct; 15 (5): 801-20.
Loder E, Burch R, Rizzoli P. The 2012 AHS / AAN mirayiridzo yekudzivirira kwechirwere chepisodic: chidimbu uye kuenzanisa nemamwe magwaro ekupedzisira emitambo yekliniki. Headache . 2012; 52: 930-45 .
Loo CY, Tan HJ, Teh HS & Raymond AA. Randomized, open label, yakarongedzwa muedzo we celecoxib mukurapa kwemazwi akaoma migraine. Singapore Med J. 2007 Sep; 48 (9): 834-9.
US Food and Drug Administration. (July 9, 2015). FDA Mishonga Yekuchengetedzwa Kwemishonga Kukurukurirana: FDA inosimbisa kunyevera kuti kwete-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) inogona kukonzera kushungurudzika kwemwoyo kana kurohwa.
US Food and Drug Administration. Mishonga Inotungamirirwa neHasina-Steroidal Anti-Inflammatory Drugs (NSAIDs).