Zvikonzero Zvokushandisa uye Maitiro Akashata eCorticosteroids neCancer
Steroid inowanzoshandiswa kuvanhu vane kenza nekuda kwezvikonzero zvakawanda. Ndeipi chaizvo iyo corticosteroids? Ndeapi mabasa aanoita mukurapa kenza? Ndezvipi zvimwe zvinowanzoitika kwenguva pfupi uye kwenguva yakareba migumisiro, uye zvingaita sei kuti iwe unzwe mafungiro ako?
Ndezvipi Steroids (Corticosteroids)?
Steroidzi makemikari zvinowanzobudiswa mumitumbi yedu nemagland endocrine, ayo anoita basa rinokosha pakuronga mabasa emuviri.
Zvimwe zvezvi zvinosanganisira:
- Mutemo wemvura uye munyu womuviri
- Mutemo wekushisa muviri
- Mutemo weropa
- Metabolism yemafuta, makhahydrates, uye mapuroteni
- Kutonga "kushushikana kwepfungwa" yemuviri
- Mutemo wekuputika
- Kugadzirisa zvirwere
- Kushushikana mupfungwa (ona pasi apa)
Ndeipi Steroid inoshandiswa muCcercer Therapy?
Apo patinofunga nezveumwe munhu anotora steroidhi, tinowanzofunga nezvevatambi vemasisitomu-vakasungwa kana kuti vanoremesa muviri. Recreational steroids, yakafanana neyo inorondedzerwa pamusoro apa, inonzi vanabolic steroid uye haisi inowanzoshandiswa mukuchengetedzwa kwekenza.
Kazhinji kacho, steroid inoshandiswa kune vanhu vane kenza inonzi corticosteroids . Corticosteroids imakemikari zvinowanzobudiswa neadrenal glands, zviduku zvegoutocrine zvinogara kumusoro kwetsvo. Mienzaniso yemhando idzi dze steroid ndeyokuti:
- Cortef (hydrocortisone)
- Deltasone (prednisone)
- Kutungamirwa (prednisolone)
- Decadron (dexamethasone)
- Medrol (methylprednisolone)
Kana inoshandiswa nekenza, mishonga iyi inowanzopiwa muromo kana injowa mukati-kati (nokuda kweimwe mamiriro ezvinhu inogonawo kunge iri chikamu chekugadzirira, injowa muzvibatanidzi, kana kuvharidzira kuburikidza nemushonga kana muchera inhaler).
(The corticosteroid converter inogona kushandiswa kuenzanisa dhidhi yeimwe yemishonga iyi kune imwe.)
Zvikonzero zvekushandisa steroid muCcercer Treatment
Steroid (corticosteroids) inogona kushandiswa kune zvikonzero zvakasiyana-siyana mukurapa kenza. Izvi zvinogona kuvhiringidza, uye zvakakosha kubvunza oncologist yako pamusoro pechinangwa chaicho chemishonga yaunorayirwa.
Zvinoshandiswa kushandiswa kwe-corticosteroids nekenza zvinosanganisira:
- Kuti ubatsire kudzivirira kugadziriswa kwehutachiona kuwedzerwa ropa kwekodhi kana mishonga - Steroid inowanzoshandiswa (pamwe chete nema antihistamines nemimwe mishonga) kudzivirira zvinokonzera zvirwere. Imwe chemotherapy yemishonga, yakadai seTareol (paclitaxel) inowanzokonzera kugadzirisa kwehutano. Allergic reactions to rituximab , rudzi rwechirwere chinotarisirwa chinoshandiswa nekenza dzine chokuita neropa zvakanyanya. Steroid inowanzopiwa panguva imwechete iyo iyi mishonga sekudzivirira chiyero.
- Kubatsira kudzora chemotherapy-induced nausea uye kurutsira - Sezvo nekugadzirisa manzwiro, steroid inowanzoshandiswa pamwe nemimwe mishonga yekudzivirira kana kubata chirwere chinosuruvara.
- Kuwedzera chido - Muhutano hwedu hunorema, tinowanzotarisa kuora kwekureruka sekuwedzera. Asi chirwere cachexia -makwikwi ezviratidzo zvinosanganisira kusagadzikana kwekureruka kwemazivi uye kuparara kwemasisita-inokonzera kusvika 20 muzana yekufa kwekenza, zvichiita kuti zvive zvakakosha kugadzirisa zvinetso zvakadai sokurasikirwa kwechido kune vanhu vane kenza .
- Sezvo chikamu che chemotherapy yako regimen.
- Kuti kuderedza kuputika.
- Kuchengeta marwadzo.
- Kuchengetedza kugadzikana kweganda.
- Kurapa kupfupika kwefema mumukenza unobudirira.
- Kupedza kudzima kana kenza inopararira kuuropi ( neuropi metastases ).
- Kuti kuderedza kuzvimba mumutsipa wepelinha kukanganiswa - Mutsara wekudzvinyirira mutsara inowanzoonekwa ne myeloma uye nezvimwe zvirwere zvinopararira kumapfupa (bone metastases).
- Kuchengeta zvakanyanya vena cava obstruction (chinetso chekenza).
- Kubatsira kubata chirwere chekudzivirira (sechinhu chinokonzerwa nekenza).
- Kuchengetedza kubatanidzwa-ne-host host (GVHD) inotevera stem cell transplant .
Kunzwisisa Cortisol uye Kupindura Kwepfungwa
Kuti uzonzwisisa kuti steroids inogona kushandiswa sei kune vanhu vane kenza, zvinobatsira kuongorora kuti "steroid" chaiyo inoshanda mumuviri uye kukosha kwekushandisa mishonga iyi sezvinorayirwa.
Apo miviri yedu yakamanikidzwa-ingava mumuviri kana mupfungwa-chiratidzo chinotumirwa kune chirwere chepituitary, chirwere chiduku chinopedzisira chiri muuropi. Plandish gland inotumira hormone inonzi adrenocorticotropic hormone (ACTH). ACTH, zvakare, inorayira zvipembenene zvinonzi adrenal (zvinyorwa zviduku zve endocrine zvinogara kumusoro kweivo) kusunungura cortisol, "steroid yemasikirwo."
Cortisol iyo inotora chikamu chinokosha pakugadzirisa kushungurudzika, kuburikidza nokuchinja kupisa, kupindura kutapukirwa, uye mamwe mabasa akawanda. kubva pakutevedzwa kwemafupa eropa kusvika kukutarisa kwehuga yeropa.
Mishonga inogadzirwa yakagadzirirwa steroid inoshanda zvakadai sa cortisol. Iyi mishonga ine simba ine zvakawanda inoshandiswa mukurapa uye inokosha pakurapa kwekenza dzine chokuita neropa, zvakadai seukamiaia, lymphoma, uye myeloma, pamwe chete nekenza yakasimba.
Migumisiro Yechipfuva Steroid Shandisa
Iyo migumisiro yemaSteroid inowedzera kuipa kana iyo inotorwa pamvura yakakwirira uye kupfuura kwenguva yakareba kwenguva. Kana uri kudzidza nezvemigumisiro, unogona kuona ichivhiringidza, sezvo migumisiro yemigumisiro yevanhu inotanga kufambisa paanotora mishonga iyi kazhinji inopesana nemigumisiro inowanikwa nekushandisa kwenguva refu. Pakutanga iwe ungaona simba rakawedzerwa pane steroid, asi pamusoro penguva yakareba, iwe ungaona utera.
Kunzwisisa "mhinduro yezvinyorwa" mukugadzirwa kwemaromu emasimba mumuviri kunogona kubatsira kutsanangura izvi. Kuziva nezve "feedback loops" kunogona kukubatsira kuti unzwisise kuti nei usingafaniri kukanganisa mishonga iyi nekukurumidza kana kuderedza kudarika kwaunoita iwe kana wave uchivatora kwenguva yakareba.
Pakutanga paunotora madhiragi aya (hormone), iwe unogona kunyatsofunga nezvemishonga se "kuwedzera" muviri wako wekugadzira corticosteroids. Nokufamba kwenguva, muviri wako unoziva kuti uri kuwana yose ye corticosteroids yaunoda mupiritsi kana mavara, uye muviri wako unotumira shoko kuti urege kubudisa yako chaiyo corticosteroids. Kana mishonga iyi ikangoerekana yakamira, iwe hausi kungotora mishonga, asi inogona kutora nguva yakawandisa muviri wako usati waona kuti inoda kugovera corticosteroids zvakare.
Mhedziso dzenguva pfupi (migumisiro inowanikwa kare kana steroid inoshandiswa kwenguva pfupi chete) inosanganisira:
- Kunyunyuta - Kune zvakawanda zvinokonzera kusuruvara nekenza, asi iyo inobatanidza ne-steroid, kunyanya iyo inopiwa panguva yekemotherapy, inogona kuva yakaoma.
- Allergic reactions - Kazhinji, kunyange zvazvo steroid inowanzoshandiswa pakugadzirisa zvirwere, vamwe vanhu vangave vane chirwere chinokonzera kugadzikana kune steroid .
- Delirium - Kusanganiswa, uye delirium inogona kuitika, kunyanya apo inosanganiswa nemarwadzo emarwadzo emarwadzo muvanhu vane kenza yakanyanya.
Nguva yakareba migumisiro yemaSteroid inowanikwa uye inogona kusanganisira:
- Kuvharidzirwa kwepachivha uye zvirwere - Steroids chete inogona kutungamirira kukudzivirira kwekuzvidzivirira kwezvirwere izvo, kana kuwedzerwa kumapfupa emapfupa okuderedza nemhaka yeronda mumarro kana chemotherapy, inogona kuva yakaoma. Izvi zvinogona kuwedzera mungozi yako yehutachiona kana kuita kuti zvirwere zvive zvakanyanya.
- Kuwedzera kwehuwandu - Vanhu vanotora steroidhi kwenguva yakareba vanowanzopedza kune zvinonzi "moon facies" umo mafuta akawanda anowedzera kumativi echiso.
- Kushayiwa simba (kunyanya kukanganiswa kwemaviri musimba).
- Mafungiro kana mafungiro anopindira (ona pasi apa).
- Chironda chepondach uye gastritis - Dzimwe nguva vanhu vane steroid vanopiwa mushonga wemishonga yekuderedza mukana wekuvandudza maronda.
- Yakawedzerwa ropa.
- Kurara kuvhiringidzika.
- Yakawedzerwa shuga yeropa (kunyanya kukosha kana iwe uri chirwere cheshuga) - Hazvisi zvisinganzwisisiki apo masero akawanda e steroid anoshandiswa kuti munhu ave "kwenguva pfupi" ane chirwere cheshuga uye anoda insulin ( steroid-induced diabetes ).
- Osteoporosis (brittle bones) - Kunyange kushandiswa kwenguva pfupi kwe steroid kunogona kukonzera kurasikirwa kukuru kwemapfupa, izvo zvinogonawo kuwedzera ngozi yezviputsi.
- Dzorera maoko kana tsoka nokuda kwemvura uye kuchengetedza munyu.
- Cataracts.
- Acne.
Dzimwe mimwe migumisiro inogona kuva yakanaka kana yakaipa zvichienderana nehutano hwemunhu. Semuenzaniso, kuwedzerwa kwechido uye kuwedzera kwekuwedzera kunogona kubatsira kune vanhu vane urombo pasi pekenza.
Kutora mishonga yako nechingwa kunogona kubatsira kune zvimwe zvinetso izvo steroid inogona kukonzera kugadzikana kwako kwekudya. Iwe unogonawo kusarudza kutora mhando idzi dzemishonga pakutanga kwezuva kuitira kuti dzisaita zvishoma kuti dzisavhiringidza kurara kwako usiku.
Sezvo nemishonga yakawanda yemigumisiro, iwe oncologist, mukoti, kana kuti mishonga inogona kukupa mazano ekubatsira kudzora kana kuderedza. Iva nechokwadi chekutendera chiremba wako kuziva kana iwe uchinge waona chero zviratidzo kana madhara.
Impact yeSteroids paMood
Kunyange iwe ungangodaro wakanzwa mashoko okuti "kutsamwa kukuru," iyo inoshandiswa kurondedzera maitiro ekutsamwa uye kuputika kwevanhu vanotora vanabolic steroid, zvakakosha kuziva kuti corticosteroids inogonawo kuva nemigumisiro yakaipa pamafungiro.
Mafungiro emagariro e-corticosteroids anogona kubva pakutsamwa, kusazvidzora, uye kutsamwa kusvika munzira yepanoia, kuvhiringidzika, uye mania. Asiwo, hazvishamisi kuva nemafungiro asina kunaka kana kunyanya kuora mwoyo mushure mokurega mishonga iyi.
Zvinosuruvarisa, nezvose zviri kuitika muupenyu hwako nekenza, zvingave zvakaoma kuziva kuti chii chinokonzerwa nemanzwiro aya. Hongu, iwe uri pane steroids, asi iwe uri kutorawo kurapwa kwekenza uye uchiedza kurarama hupenyu humwe huri hupenyu. Zvakajairika kuti uwane manzwiro akasiyana-siyana paunenge uchitarisana nekenza .
Mutemo mukuru wegunwe ndewokuti kana mafungiro ako achichinja ari kuchinja hupenyu hwako kana hutano hwehukama hwako, unofanirwa kutaurirana ne team yako oncology. Kana manzwiro ako akaoma, iwe unogona kutsvaga kutsvaga rubatsiro.
Zvakakosha Pamusoro Pokutora Steroids
Sezvo mune mishonga yakawanda yekurapa mishonga, zvakakosha kutora steroid chaizvo sezvinotsanangurwa nachiremba wako. Heano mimwe mibvunzo yakanaka kubvunza sangano rako rehutano nezve steroid yako usati watanga:
- Ndichatora nguva yakareba sei kutora mishonga iyi?
- Ndiani wandingabvunzurudza kana ndiine chirongwa chakakomba chemishonga iyi?
- Zvakadini kana ndikashayikwa nechirwere? (Usangotora mimwe miviri yemishonga).
- Ko kana ndikarutsa mishonga yangu?
- Ndeipi migumisiro yechirwere yaunowanzoona nayo iyi mishonga pamwe chete kwenguva pfupi uye nekushandisa kwenguva refu?
Dzivisa Kuerekana Kuregererwa kweSteroids
Sezvambotaurwa, kutora steroid mishonga inobatsira pakuwanda kwechirotero steroid muviri wako unobereka. Nokuda kwechikonzero ichi, kana steroid yako isingadiwi sechikamu chekurapa kwako, chiremba wako anowanzotora muzinga wacho panzvimbo pokudzimisa pakarepo. Zvinonyanya kukosha kuti urege kurega kutora mishonga iyi kunze kwekunge iwe uchiudzwa nachiremba wako. Muzviitiko zvisingawanzoitiki, kumisa steroid kamwe kamwe kunogona kukonzera upenyu hunotyisa adrenal dambudziko.
Kunyangwe iwe uri kutevera purogiramu yekufungidzira, regai chiremba wako azive kana zviratidzo zvako zvinotambudza. Vamwe vanhu vanofanirwa kubviswa pamishonga iyi zvishoma nezvishoma pamusoro pevhiki kana mwedzi.
Pasi Pasi paSteroids muCcercer Treatment
Steroidzi ma heroes asingagoni kugadziriswa nekenza. Kunyange zvazvo chemotherapy, remishonga yehutachiona, uye kunyanya inotanga kurapwa mishonga uye immunotherapy inowana rumbidzo yekenza yekuuraya, steroid inoshanda zvinyararire mushure memaziso, kudzivirira uye kugadzirisa zvinetso uye kunyange kuita kuti dzimwe kurapa zviite zvakanaka. Ndicho chikonzero ivo vanoita basa guru mukurapa kweaviri inokonzerwa neropa uye zvironda zvakasimba.
Izvozvo zvakati, madhiragi aya ane nhamba inokosha yehupfupi uye yakareba yemigumisiro yemigumisiro, dzimwe dzingave dzakaoma. Iva nechokwadi chekuti mubvunze mibvunzo uye utaure pamusoro pezviratidzo chipi zvacho zvauri kuitika, kunyange kana iri "chete" kuneta. Iva iwe pachako mupepeti mukuchengetedzwa kwekenza yako .
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