I HPV Inoita Kuti Lung Cancer? Causation vs. Correlation

Ko HPV Zvirwere Zvingaita Kuti Uve Nengozi Yenyu Yemahara?

Mukuongorora kwemashure makumi mashanu makumi mashanu nemakumi matatu nemashanu kubva kuongororo yakabudiswa mupepanhau reLung Cancer , vanyori vakataura kuti HPV inogona kuva yechipiri inokonzera chirwere chemapapu mushure mekusvuta fodya, uye tsvakurudzo yakawedzerwa panyaya iyi yaida chaizvo. Chii chatakadzidza kubva panguva iyoyo? Pane humwe hukama hwehumwe huri pakati peHIVV nemukenza wemapapu here?

Chii Chinonzi HPV (Human Papillomavirus)?

HPV (munhu wepillomavirus) inoungana nemavirusi anopfuura 200 anogona kuuraya vanhu.

Pakati idzi, zvinenge makumi matatu makumi matatu zvinokwanisa kukonzera chirwere chepabonde, uye inowanzo "marwa-kukonzera" maronda ari HPV 16 uye HPV 18.

HPV inowanzopararira kuburikidza neganda-kune-ganda, rinowanzoita zvepabonde. Kuwanda kwezvirwere neHIVV zvakajeka zvisingatauri mukati memakore maviri pasina kuwedzera mamwe matambudziko, asi dzimwe nguva dzinoramba dziripo. Kutapukirwa ne "kenza-inokonzera" utachiona hweHIVV hazvirevi kuti munhu achava nekenza. Zvechokwadi, zvirwere zvakawanda neHIVV hazviiti kuva kenza.

HPV inozivikanwa kuti inokonzera epithelial masero uye inoshanda kuvhiringidza hutachiona hutachiona hunotungamirira masero ekukura. Kunyange kana izvi zvikaitika, mazhinji emasero aya asingaoneki achaonekwa uye abviswa nemasikirwo edu ezvirwere.

HPV neCancer

HPV ikozvino yakagadziriswa sekuita nharaunda mumatambudziko akawanda emukenza wechibereki, pamwe chete nematambudziko mazhinji evanhu vanorwara nekenza, kenza yepenile , inenge 95 muzana yekenza yakakonzerwa, uye 70 muzana yekenza yepamuromo, zvikurukuru iyo inowanikwa mudiki, kwete -kubika vakadzi.

HPV 18 uye HPV 16 ndiyo inokonzera inenge 70 muzana yeHIVV-inokonzerwa nekenza yekervical, uye HPV 16 inotarisirwa kwehafu yeHIVV inokonzera kanzura dzemuromo.

Nokudaro, tinoziva kuti zvirwere zveHIVV zvinogona kukonzera kenza uye kuti inokonzera mamwe kanzira pedyo nepapu. Isu tinozivawo kuti zvirwere zvehutachiona zvinogona kuita kuti pave nekenza yemapapu, somuenzaniso, avo vane HIV vane hutachiwana vanowanzova nekenza yemapapu kune avo vasina kutapukirwa neHIV, asi zvinogona kukonzera kenza yemapapu here?

Chirwere Chinokonzera Chirwere Chinokonzera Nengozi

Kutarisa zvinokonzera kenza yemapapu zvakakosha zvikuru. Zvinosuruvarisa, kushorwa kwemukenza wemapapu chirwere chinoputika mune dzimwe nzira zvakaderedza kufambira mberi pakuongorora zvimwe zvinokonzera. Asi kenza yemapapu inowanikwa kune vasiri vasvuta pamwe chete. MuUnited States, 20 muzana yevakadzi vanova nekenza yemapapu havana kumbosvuta fodya imwe chete, uye nhamba iyoyo inokwira kusvika ku50 muzana yevakadzi vane kenza yemapapu pasi rose avo vari vapenyu vese vasina kusvuta. Zvechokwadi, mutanho wemapapu muvanhu vasiri kusvuta ndewechitanhatu chinotungamirira chikonzero chekufa kwekenza muUnited States.

Isuwo tinoziva kuti havasi vose vanoputa vanowedzera kenza yemapapu, uye iyo kusvuta inogona kushanda muchienderana nemamwe ngozi anokonzera kenza. Iko HPV imwe yezvinhu izvi here?

Nhoroondo uye Geography yeHIVV neLung Cancer

Kubvira kuti HPV inogona kuita basa mukugadzirwa kwekenza yemapapu yakatanga kutaurwa muna 1979. Zvidzidzo zvakawanda kubvira panguva iyoyo zvakawana uchapupu hweHIVV DNA mumakondomu emapapu, asi izvi zvinowirirana zvakanyanya zvichienderana nejw.org . MuUnited States, HPV DNA inowanikwa munenge 15 muzana yemakirini emapapu, zvichienderana nekudzidza, neHIVV 16 neHIVV 18 inowanzowanika-iyo mishonga inowanzobatwa nekenza yemukondombera.

MuEurope, kuvapo kweHIVV DNA mumakondomu emapapu kune mamiriyoni 17 muzana, asi nhamba iyi inosvika 69 kubva muzana muGrisi neTaiwan uye 79 muzana muJapan. Isu tinoziva kuti mutsa wekumapapu mune vasiri vasvuta unozivikanwa zvikuru muAsia. Isu tinoziva zvakare kuti HPV inoratidzika kuva inowanzowanikwa mumasero emukenza emapapu evakadzi uye vasina kusvuta kupfuura varume nevarume vanoputa.

Zvidzidzo zviviri zvegore ra2016 zvinoratidzira izvi kusiyana kwezvinhu zvakatowedzera. Mune rumwe ruzivo, zvakawanikwa kuti vakadzi vokuTaiwanese vainyanya kuve nekenza yekenza yemapapu kana vakave vakananga neHIVV. Kusiyana neizvi, kuongorora kweChina kwakawana kusabatana pakati pezvirwere zve HPV (chiratidzo chekutsvaga) uye kukura kwekenza yemapapu.

Iko HPV Infection Cause Lung Cancer?

Kunyange zvazvo HPV inowanikwa mumasero emukenza emapapu, kunyanya mu squamous cell carcinoma yemapapu , kukosha kwekliniki yekuwana HPV mumasero ekenza yemapapu hazvizivikanwe kana kunzwisiswa. Ngatitarise zvimwe zvezvikonzero kuti mubvunzo uyu usapindurwa nyore nyore.

Causation vs. Correlation

Pasinei nokuti kuvapo kweHIVV mumukenza wemapapu kunoratidza causation (iyo iyo HPV inokonzera chirwere chemapapu) mumwe mubvunzo. Chero nokuti pane kuwirirana pakati pezvinhu zviviri-munyaya iyi kuvapo kweHIVV nekukura kwemukenza wemapapu-hazviiti chinhu pamusoro pekuita. Nzira inonyanya kutsanangura iyi ndeyokushandisa muenzaniso. Pane kuwirirana kwakasimba pakati pekudya ice cream uye kunyura asi izvo hazvirevi kuti kudya ice cream kunokonzera kumira kunenge kuchiitika. Muchiitiko ichi, pane kuwirirana pakati pezvinhu zviviri izvo zvisiri izvo zvisingaenderani.

Mukuwedzera, panzvimbo yekukonzera kana kusawirirana kusina kubatana, kuvapo kweHIVV nemukenza wemapapu kunogona kunge iri "mubvunzo wekuku uye yei" mubvunzo. Chii chakauya pakutanga? Zvichida mapepa emapapu ayo akaparara nekuvapo kwekenza inowanzosangana neHIVV. Kana izvi zvikaitika, HPV yaizoonekwa se "utachiona husina kunaka" hwakafanana nehutachiwana hwevanhu vane HIV. NeAIDS, ndiko kukanganisa kunokonzerwa neHIV inoshandura muviri kuti uwane zvirwere zvakadai sepneumocystis pneumonia, kwete zvimwe zvirwere zvinokonzera HIV.

Primary Pung Cancer vs. Metastases

Mune zvimwe zvidzidzo, mutanho wemapapu unoratidzika kuva wakajairika kune avo vane chirwere chemucheche wechibereki. Mune imwe yakanyatsodzidza zvidzidzo (izvo zvakagumisa kuti HPV haina kuwanzoti kana yakambobatanidzwa nekwakapinza kenza yemapapu muCanada neNorth America), yakawanikwa kuti utachiona hweHIVV hwakanga huri muzana chete 1.5 muzana yevarwere, uye kuti vose ava varwere vakanga vaona kare zvikwereti zvinokonzerwa nekenza (zvakadai sekondomu kana kenza yemuromo) zvine chokuita neHIVV. Kunyange zvazvo makondomu aya emapapu akaonekwa ari mapepa ekutanga emapapu, mubvunzo wakakudzwa ndewokuti panzvimbo iyo, zvirwere izvi zvinogona kureva mutsara wemastasita kumapapu kubva kumakondombera anobva kumuromo wemukomana uye emuromo.

HPV seCarcinogen

Tine chokwadi chekuti HPV inoshanda semakemikari- chikonzero chinokonzera kenza- kana ichiuya kumuromo wemukati, penile, mumukadzi, uye mumuromo wekenza, asi zvakadini nekenza yemapapu? Kana iHIVV inobatanidzwa mumukenza wemapapu, pfungwa yezvino inoratidzika seyokuti HPV inogona kunge yakabatana mukutsika kenza yemapapu. Mune mamwe mazwi, hutachiona hunogona kushanda pamwe chete nedzimwe njodzi dzakadai saRaddon kana kushambadzira fodya kubudisa kenza. Inofungidzirwawo kuti, kusiyana nekenza yemukomana, kana HPV iine chikonzero kana chibatanidza mumapapu emapapu, zvichida izvi zvinongogumira kune mamwe mapepa emapapu emapapu.

HPV nemaronda emaronda

Zvinofadza kuti vanhu avo vane humwe hutano hweHIVV mumasero emumapapu emapapu vanoita kunge vane huwandu hwakanaka kune avo vasina humwe hutano hweHIVV mumasero emukenza emapapu. Izvi zvinopa chikonzero chebasa rinogona kuitwa reHVV mukenza yemapapu kana ichifananidzwa nemakondomu omuromo. Makondombera omumuromo anokonzerwa neHIVV anowanzova nehuwandu hwakanaka kupfuura huya hunobatana nekushandisa fodya.

Pasi Pasi

Zvichida pane imwe nguva tisati taziva chii, kana chiripo, ukama hwechokwadi pakati peHIVV nekenza yemapapu zvechokwadi. Sezvakataurwa, kune mhando dzakawanda dzatisati tazvinzwisisa. Kuwedzera kutsvakurudza kuchadiwa kuti uongorore kuvapo kweHIVV mumasero emukenza emapapu, uye kutsanangura maitiro makuru evanhu vanoita seanovapo. Sezvakataurwa pamusoro apa, kunyange kuwirirana zvakajeka pakati peHIVV nekenza yemapapu hazviratidzi kukonzera. Zvinogona kuva kuti hazvibatanidzi, kana kunyange iyo mutsara wemapapu emapapu inowanzosangana nehutachiona neHIVV uye kuti mukenza wemapapu "chikonzero" chepachirwere cheHIVV pane imwe nzira yakapoteredza.

HPV Kudzivirira

Saka izvi zvinorevei pakudzivirira? Kuderedza kusvikirwa neHIVV kuburikidza nekuita zvepabonde zvakachengeteka kutanga kwakanaka. Kune avo vari mufambo pamusoro pemushonga weKVV , izvi zvinogona kupa zvishoma zvishoma rubatsiro.

Chinhu Chinopera Chine Mungozi yeKenza

Tinofara kuti tinoziva nezvezviitiko zvakasiyana-siyana zvinokonzerwa nekenza yemapapu pane zvatine simba. Tarisa aya mazano gumi ekudzivirira kenza . Iva nechokwadi chokuti wakaita kuti imba yako iongorore radhidon - chinokonzera chirwere chemapapu mune vasiri kusvuta uye funga kuwedzera zvimwe zvezvokudya izvi zvinofanirwa kuderedza dambudziko rekenza yemapapu kune kudya kwako. Uye usakanganwa: ani naani ane mapapu anogona kuwana menza yemapapu.

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