A Review of Zvinokonzera, Kuongororwa, uye Kurapa kweEosinophilia
Eosinophilia ndiro zita reumhizha rekuwedzera kweeosinophil count. Eosinophils ndiwo rudzi rwemachena masero eropa anoparadza zvinhu mumuviri sepasisiti uye anobatanidzwa mune zvinokonzera zvirwere.
Chii Chinokonzera Eosinophilia?
Pane zvikonzero zvakawanda zvekuti eosinophil inogona kuve yakakwirira. Zvimwe zvezvikonzero zvinokonzera uye zvinoda kurapwa zvishoma.
Hazvisi zvisinganzwisisiki kuti nhamba yakakwirira igare kwenguva refu uye isarudze pasina kurapwa. Ngationei zvimwe zvezvikonzero zvino.
- Zvirwere zvepachirwere: Munyika yose chikonzero chinowanzokonzera eosinophilia chirwere chepachirwere. Mazita ehutachiona aya anosanganisira schistosomiasis, trichinosis, strongyloidiasis, uye ascariasis. Izvi zvinogona kuwanikwa munyika yose kusanganisira United States. Nhoroondo yekufambisa chikamu chakakosha chebasa-re eosinophilia kunyangwe kushayikwa kwekufambisa kwemazuva ano hakurevi kutapukisa kwepachivi. Kurwara kwevanhu vanofambira kune chirwere chepachirwere chetachiona asi hachiwanzobatanidzwa ne eosinophilia.
- Kuita zvinodhaka: Mishonga inogona kukonzera eosinophilia, dzimwe nguva pasina zviratidzo zvakajeka kana zviratidzo. Mishonga inowanzojairika inosanganisira eosinophilia inosanganisira antibiotics (penicillin, cephalosporins), kwete-steroidal anti-inflammatory medication (aspirin, ibuprofen), ranitidine (yegastroesophageal reflux), phenytoin (anti-seizure) uye allopurinol (inoshandiswa kurapa gout). Chimiro chakakomba chinonzi drug reaction ne eosinophilia uye systemic zviratidzo (DRESS). Nenzira yakanaka, vanhu vakawanda havazovi nemhinduro idzi pavanowana mishonga iyi.
- Atopy : Atopi inyaya inowanikwa mumuviri. Kazhinji, inopy inotaura nezvechirwere, zvipembenene zvemwaka (zvinonziwo allergic rhinitis), uye eczema. Hazvishamisi kuti mumwe munhu ave nezvakawanda pane izvi zvehutano sezvavanenge vakabatana. Izvi ndezvimwe zvikonzero zvinonyanya kukosha zvekunaka kusvika pakuenzanisa eosinophilia, kunyanya kuvana. Saizvozvowo, kudya kwezvokudya kunogona kukonzera kukwirira kwakanyanya kweeosinophil.
- Eosinophilia esophagitis (EoE): Ichi ndicho chirwere chinoratidzwa ne-eosinophils inopararira kune sophagus inowanzo isina eosinophils. Inenge 50% yevanhu vane EoE ichavewo yakasimudzira eosinophil kukosha muropa.
- Hypereosinophilic syndromes : Hyperoeosinophilic syndromes (HES) iboka rematambudziko rinoratidzwa nepamusoro-soro eosinophil zvikwereti uye uchapupu hwehupombwe hwemuviri kubva kuhuwandu hwemaosinophils. Nhengo dzinowanzotarisirwa iganda, mapapu, uye masumbo. HES inogona kuva yepamusoro (inonziwo neoplastic) yechipiri (reactive) kana idiopathic (chikonzero chisingazivikanwi).
- Churg-Strauss Syndrome: Churg-Stauss vasculitis, yava kunzi eosinophilic granulomatosis ne polyangiitis, inogona kukonzera eosiniophilia. Vanhu vane chirwere ichi varipo nehutenda nemamwe mapapu emapapu pakutanga, zvino ivai eosinophilia, uye pakupedzisira vasculitis , kuputira kwemidziyo yeropa.
- Cancers: Kune maronda akawanda emukenza, kunyanya zvirwere zvekenza, izvo zvinozivikanwa nekuwedzera eosinophil count. Izvi zvinosanganisira rudzi rushoma rwemuteyo myeloid leukemia (AML) inonzi eosinophilic leukemia. Zvimwe zvinokonzera zvinosanganisira zvinyorwa zvemyeloproliferative neoplasms (zvakadai, inokosha inonzi thrombocythemia, polycythemia vera) B-cell uye T-cell lymphoma, uyewo adenocarcinomas yechipfuva chemuviri, mapapu, uye chibereki.
Ndezvipi zviratidzo zveEosinophilia?
Kana iwe uine eosinophilia, zviratidzo zvako zvichatsanangurwa nechikonzero chepamusoro ye eosinophilia count. Kana yako eosinophil nhamba yakanyatsokudzwa iwe unogona kunge usina zviratidzo. Zviratidzo zvinozivikanwa zvinosanganisira:
- Mapundu
- Itching
- Dhairrhea, munyaya yezvirwere zvepasisite
- Asthma
- Runny mphu, kunyanya kana ichibatanidza nehutano.
Eosinophilia Inowanikwa Sei?
Kufanana nematambudziko akawanda eropa, eosinophilia inoratidzirwa pahuwandu hwekuverenga ropa (CBC) . Eosinophils imwe yemasero machena eropa uye anowanikwa mune chikamu cheCBC chinonzi chakasiyana. Kusiyanisa kunoshuma kuti vangani vemarudzi ose emasero machena (neutrophil, lymphocyte, monocyte, eosinophil, uye basophil ) varipo muropa.
Mushure mekutsanangurwa kweEosinophilia, mutapi wako wehutano achatanga kushanda kuti aone chinokonzera, dzimwe nguva izvi zvinoda kutumirwa kune anhematologist. Kuoma kweeosinophilia dzimwe nguva kunogona kutungamirira basa-up rinodiwa. Eosinophilia inogona kuenzaniswa nenhamba ye eosinophils (absolute eosinophil count).
- Unyoro: 500 - 1500 masero / mL
- Mutevedzeri: 1500 - 5000 masero / mL
- Yakakura:> 5000 masero / mL
Kugadzirisa chinokonzera eosinophilia kuchave kuchibva pane zviratidzo zvako. Eosinophilia esophagitis inogona kukonzera kuoma, chifuva uye / kana kurwadziwa kwepamuviri, kurutsira kana kudya kunonamatira muhutano. Kuongororwa kunoda biopsy yeeophagus. Zvizhinji zvehutachiona hwehutachiona hunoonekwa nekutora zvidzidzo zvemukoko uye kuidziidza. Ikoko hakungavi nemuedzo kuti uone kana mishonga inokonzera eosinophilia yako. Kana yako eosinophil count inodzokera kune yakasununguka mushure mokurega mishonga, inowanzofungidzirwa kuti mishonga ndiyo yaiva iyo mhaka.
Ndezvipi Zviratidzo Zvimwe ZveEosinophilia?
Zvakafanana nechinoridziro chinogona kudiwa, kurapwa kunotsanangurwa nechikonzero cheEosinophilia. Zvimwe zvinosanganisira:
- Kucherechedza: Kana yako eosinophilia iri munyoro, kucherechedza nekudzokorora mabhii kunogona kukurudzirwa.
- Kana mishonga ichikonzera yako yakakwirira eosinophil count, inogona kudziviswa
- Kuwedzera kurapwa kwechirwere, eczema, uye kurwara
- Zvirwere zvepachirwere zvinoshandiswa nemishonga inorwisa-parasitic.
- Steroid yakadai seforenisone inogona kushandiswa kurapa hyperereosinophilic syndromes
Shoko Rinobva
Hypereosinophilia ishoko rinotyisa-rinonzwika. Nenzira yakanaka, kune vanhu vakawanda vane chirwere ichi, chinoitika kwenguva duku uye inoda zvishoma kudarika kurapwa. Kune vamwe, kuongororwa uye kurapwa kungadikanwa kutumira kune imwe nyanzvi. Kana uine zvimwe zvinonetsa, iva nechokwadi chekukurukurirana navo nechiremba wako.
> Kwakabva:
> Weller PF uye Klion AD. Nzira kumurwere nemusina kutsanangurwa eosinophilia. Mu: UpToDate, Post TW (Ed), UpToDate, Waltham, MA.