Zvaunoda Kuziva
Huperzine A ichinhu chakabudiswa kubva mumunda unonzi Chinese club moss ( Huperzia serrata ). Muchizvarwa chemishonga chinonzi Chinese , chiChinese club moss yakagara yakashandiswa kuderedza kuputika uye kuwedzera kurangarira. Kutengeswa sekuwedzera kwekudya, huperzine A inowanzoitwa senzira yekurapa chirwere cheAlzheimer .
Zvishandiso
Iyo inoshandiswa mune imwe nzira yekurapa, huperzine A yawanikwa ichiita seinterlinesasease inhibitor, rudzi rwemishonga inoshandiswa kudzivirira kuparara kweacetylcholine (ikemikari inokosha pakudzidza nekuyeuka).
Haisi kungoshandiswa sechirwere chechirwere cheAlzheimer, huperzine A inonziwo kusimbisa kudzidza nekuyeuka nekuchengetedza pakusangana kwehupenyu hwehutano hwekuzvarwa.
Mukuwedzera, huperzine A dzimwe nguva inoshandiswa kuwedzera simba, kuwedzera kuchenjerera, uye kubatsira mukurapa kwe myasthenia gravis (an autoimmune disorder iyo inokanganisa misumbu).
Batsirwa
Apo kutsvakurudza pamusoro pemishonga yehutano huperzine A ishoma, pane humwe uchapupu huperzine A hunogona kupa zvimwe zvikomborero. Hezvino tarisa zvimwe zvitsva zvinowanikwa kubva pakutsvakurudza kuripo:
1) Zvirwere zveAlzheimer
Huperzine A inoratidzika kuva yehumwe rubatsiro kune vanhu vane chirwere cheAlzheimer, maererano nekuongorora kwekutsvakurudza kwakaitwa muna 2008 kwakabudiswa muChishrane Database yeChechi chekuongorora.
Nokuda kwekuongororwa, vatsvakurudzi vakatsvaga miedzo yose yakarongeka pamusoro pehutano nekuchengeteka kwehuperzine A yeAlzheimer's disease. Mukutsvakurudza kwavo vatanhatu varipo maedzo (izvo zvaisanganisira vatendi vanokwana 454), vatsvakurudzi vakawana kuti huperzine A yakanga yakakosha kupfuura nzvimbobo iyo maererano nemigumisiro yekuziva, kugadzirisa tsika, uye kushanda zvakanaka.
Zvisinei, vanyori vehuturo iyi vanotaura kuti imwe chete yeruzhinji yakabatanidzwa muchirongwa ichi "yehutano hwakakwana uye hukuru." Nokudaro, vanyori vanocherechedza kuti pane "uchapupu husina kukodzera hupi hupi hunosimbisa" nezvekushandiswa kwehuperzine A yekurapa chirwere cheAlzheimer.
Mune zvimwe zvidzidzo zvenguva ichangopfuura (yakabudiswa muNeurology muna 2011), huperzine A yakakundikana kuwedzera kugadzirisa basa kune varwere veAlzheimer.
Chidzidzo chacho chaisanganisira vanhu 210 vane chirwere cheAlzheimer's mild to moderate, mumwe nomumwe wavo akagamuchira huperzine A kana placebo kwemavhiki masere. Mukutsvakurudza kwavo vanhu 177 vakapedza kudzidza, vatsvakurudzi vakawana kuti huperzine A haina kumbobatsira zvikuru pakuziva.
2) Kuvandudza Memory
Zvishoma zvidzidzo zvakaongorora kushandiswa kwehuperzine A yekuyeuchidza kukurudzira. Zvisinei, chidzidzo chekare, chiduku chiduku chakabudiswa mumutauro weChina chinoitwa Acta Pharmacologica Sinica muna 1999 chakawana kuti huperzine A akabatsira kuvandudza mhemberero nekudzidza mune boka revadzidzi vechidiki.
Nokuda kwekudzidza, 68 vadzidzi vechikoro vakuru (avo vose vakanyunyuta pamusoro pekushaya kukodzera) vakapiwa huperzine A kana placebo zuva nezuva kwevhiki ina. Nekuguma kwekudzidza, nhengo dze huperzine A boka akaratidza kuvandudza kukuru kwekudzidza nekuyeuka (kuenzaniswa nemitezo yeboka re placebo).
Kutsvakurudza kwakawanda kunotarisirwa huperzine A isati yakurudzirwa kukurudzira chiyeuchidzo.
Caveats
Kusvika parizvino, zvishoma zvinozivikanwa nezvekuchengetedzwa kwekutora huperzine A munguva refu.
Zvisinei, kune kumwe kunetseka kuti kushandiswa kwehuperzine A kunogona kukuvadza kune vanhu vane humwe hutano (kusanganisira zvinetso zvepso uye / kana zvechiropa, chirwere chemoyo , chirwere chemafi , uye vertigo) kana vanhu vanoshandisa mimwe mishonga (yakafanana nedzimwe sarudzo inhibitor, beta- blockers, uye anti-convulsive agents).
Zvichipa izvi zvinetso zvekuchengeteka, zvakakosha kuonana nechiremba wako kana uri kufunga nezvekushandiswa kwehuperzine A.
Uyezve, huperzine A inogona kukonzera migumisiro yakawanda (kusanganisira kubuda , chirwere, uye makumbo).
Zvimwe zviyero hazvina kuongororwa kuchengetedzwa uye nekuda kwekuti kudya kwezvokudya zvinowanzosaregererwa, zvinyorwa zvemimwe michina zvinogona kusiyana nezvakataurwa pane zvakagadziriswa. Uyewo chengetedza mupfungwa kuti kuchengetedzwa kwezvokuwedzera mumadzimai ane pamuviri, vanaamai vanoyamwisa, vana, uye avo vane mishonga yezvoutano kana vari kutora mishonga haisati yasimbiswa.
Iwe unogona kuwana mazano anowanikwa pakushandisa zvidimbu zvinowanikwa pano .
Kwatingawana
Iyo yakawanda inowanikwa kutenga iyo inowanikwa paIndaneti, huperzine A inotengeswa munzvimbo dzakawanda-dzekudya-zvekudya uye muzvitoro zvinonyanya kuzivikanwa zvezvokudya.
Kushandisa Izvo Kuti Utano
Pamusana pokushayikwa kwekutsigira tsvakurudzo, huperzine A haigone kurongerwa kurapwa kana kudzivirira chero dambudziko rehutano. Kana uri kutarisa kushandiswa kwehuperzine A zvidimbu, tsvaga chiremba wako usati watanga humwe hutongi huripo kuti uongorore ngozi, mararamiro uye zvakakodzera.
Zvakakosha kuziva kuti kuzviraramisa chirwere cheAlzheimer (kana chimwe chiitiko) ne huperzine A uye kudzivisa kana kunonoka kutarisirwa kwese kunogona kuva nemigumisiro yakakomba yehutano.
Sources
Li J, Wu HM, Zhou RL, Liu GJ, Dong BR. "Huperzine A yeAlzheimer's disease." Cochrane Database Syst Rev. 2008 Apr 16; (2): CD005592.
Rafii MS, Walsh S, Little JT, Behan K, Reynolds B, Ward C, Jin S, Thomas R, Aisen PS; Dambudziko reAlzheimer Cooperative Study. "Chikamu chechipiri chemuedzo we huperzine A mune unyoro kusvika kuongororwa neAlzheimer's disease." Neurology. 2011 Apr 19; 76 (16): 1389-94.
Sun QQ, Xu SS, Pan JL, Guo HM, Cao WQ. "Huperzine-A capsules inowedzera chiyeuchidzo nekudzidza kuburikidza mune makumi maviri nemaviri evanhu vanofananidzwa nevadzidzi vechidiki." Zhongguo Yao Li Xue Bao. 1999 Jul; 20 (7): 601-3.
Zvinonzwisisika: Mashoko anowanikwa pane ino yepaiti inoitirwa zvinangwa zvekudzidzisa chete uye haisi kutsiva mazano, kuongororwa kana kurapwa nechiremba ane chiremba. Hazvirevi kuvhara zvose zvinogona kumira, kushamwaridzana kwezvinodhaka, mamiriro ezvinhu kana zvinetso zvakashata. Iwe unofanirwa kutsvaga kurapwa nokukurumidza mune zvehutano kune chero hutano hwehutano uye bvunza chiremba wako usati washandisa mamwe mushonga kana kuita shanduko kune regimen yako.