HD ine zviratidzo zvakasiyana-siyana zvinogona kuitika, zvimwe zvingabudirira kuburikidza nemishonga uye isiri yemishonga. Usati waenda kune dzimwe mishonga, zviratidzo zvekunzwisisa sechikamu chechirwere chinogona kubatsirawo kutarisana navo uye kutora basa rakawanda iwe pachako kana kuti nhengo yemhuri yako.
Mhando dzezviratidzo
Semamiriro ekushaya maitiro, hunokonzera Huntington zviratidzo zvinowanzowira mune chimwe chezvikamu zvitatu: kuchinja muviri / kuchinja, kushanduka kwekufunga, uye mafungiro / mafungiro ekuchinja.
HD ndeimwe yezviitiko zvakasiyana siyana zvinoita kuti dementia iwedzere.
Zviratidzo zvinowanzokura pakati pemakore makumi matatu nemakumi mashanu. Zvisinei, vamwe vanhu vari vaduku kudarika makore makumi maviri vanovaka chirwere cheHaltington chinonzi chirwere chevana vechiHuntington.
Kuchinja Kwemuviri
Chimwe chezvinhu zvinoratidza zviratidzo zve HD ndeyechorea. Chorea inoreva kurasikirwa kwekwaniso yekudzora kufamba kwenyama. Iyo inobatanidza kushamwaridzana kunenge kusingabatsiri, kwakasimba, uye kamwe-kamwe. Izvi zvinowanzoitika mumuviri wepamusoro uye zvinosanganisira maoko kumusoro, trunk, musoro, mutsi, uye chiso. Zvinogonawo kuitika mumakumbo. Chorea iripo inenge 90 kubva muzana yevanhu vane HD uye chimwe chezviratidzo zvinowanzotarisirwa nemishonga.
Zvimwe zviratidzo zveHIV zvinosanganisira kupera mukufamba uye kutaura, kusava nekubatana, kuora mwoyo pakumedza kudya uye zvinodhaka uye, nokudaro, kushaya kurasikirwa kukuru. Pamusana pezviratidzo izvi, njodzi yekuwira inowanikwa kune vanhu vane HD, asi kushanda nevadzidzisi kunogona kubatsira kuderedza ngozi.
Kugadzirisa Kushandura
HD inokonzerwa nekuchinja kwouropi, naizvozvo zvinonzwisisika kuti mano ekufunga ane hutano. Kunyange zvazvo chiyeuchidzo chinogona kugadziriswa, dzimwe nzvimbo dzekucherechedza dzinosanganawo zvakare. Izvi zvinosanganisira kukanganisa masimba ekushanda (zvakadai sekukwanisa kuronga nekuita zvisarudzo), kusanyatsofungisisa, kusava nehanya, kusaruramisira uye kusava nekunzwisisa maitiro ako pachako.
Kusava nekudzivirirwa kunogonawo kukura. Semuenzaniso, kana une HD, unogona kuita chimwe chinhu chausingafungi chakakodzera nokuti kutora kwako kunoderera.
Kushushikana uye Kuchinja Maitiro
Zviratidzo zveHIV zvinosanganisira maitiro akawanda uye maitiro anochinja. Iwe unganzwa uchigumburwa zvakanyanya uye kutsamwa, pamwe chete nemafungiro asina kufanira anochinja. Kutaura uye kurwiswa kwepanyama kunogonawo kukura. Kutaura zvazviri, kumwe kutsvakurudza kunogumisa kuti 22 muzana kusvika 66 muzana yevanhu vane HD vacharatidza utsinye, kazhinji mumatangiro epakutanga kwechirwere.
Sezvo kune mamwe marudzi ehutano hwemagumisiro , kusava nehanya kwakajairika muHD. Kuora mwoyo (iyo yakafanana nekusava nehanya asi kazhinji kunosanganisira kunzwa kushungurudzika uye kusava netariro) inogona kuva inonyanya kukosha uye inokurudzira kwakasimba yekufunga pamusoro kana kuzvifunga kuzviuraya. Kutsvakurudza kunoratidza kuti kune ngozi yakawanda yekutonga kuzviuraya kune avo vanorarama neHD, nedzimwe dzidzo dzinoratidza kuvapo kwekuzviuraya kune vanenge 19 muzana yevatsvaga vatsvakurudzo.
Manzwiro ekuzvidya mwoyo kazhinji anowedzera kuora mwoyo. Ongororo dzekutsvakurudza dzinoratidza kuti kubva kune 34 kusvika ku61 muzana yevaya vane HD vane manzwiro ekuzvidya mwoyo.
Kutsungirira , kwaunowana "kubatisirwa" pane shoko, kufunga kana kuita, hazvisi zvisizvo.
Izvi zvinogona kuwirirana nekutadza uye kumanikidza uye kuita kuti zvive zvakaoma kuenda kune rimwe basa. Izvo zvinogona kukanganisa mafungiro asina kunaka evamwe anoita kuti zvive nyore kune vamwe kuziva kuti vangapedza sei nguva nemunhu ane HD.
Kurapa Kwazvo
Kunyange zvazvo pasina mushonga unowanika HD panguva ino, kune mishonga mishomanana uye nzira dzinobatsira dzinogona kubatsira kubvisa zvimwe zviratidzo kwenguva. Ramba uchiyeuka kuti haufaniri kushandisa zvinyorwa kana zvimwe zvekuwedzera kunze kwekutarisa nachiremba wako, sevamwe vanogona kuva nemigumisiro yakaremara yakaipa kana kusangana kwezvinodhaka nemimwe mimwe mishonga.
Sezvo pasina chirwere, chinangwa chekurapa muHD ndechekuvandudza hupenyu hwehupenyu uye kuramba uchishanda kwenguva yakareba sezvinobvira.
Mishonga
Xenazine (tetrabenazine)
Xenazine yakagamuchirwa muna 2008 neU.S. Food and Drug Administration (FDA) kuzobata chorea muHD. Yakave yakaratidzwa kubatsira kubatsira kuderedza mafambiro evanhu uye inowanzoonekwa seimwe yenzira dzakajairika uye dzinoshanda dzokubata HD.
Xenazine ano, asi, ane nyevero pamusoro pekushandisa kune vanhu vane kuora mwoyo sezvo ichiita sechiwedzera kuora mwoyo uye kuzviuraya. Zvikanganiso zvinogonawo kusanganisira zvose kugona nekushaya hope.
Austedo ( deutetrabenazine )
Austedo yakagamuchirwa neDFA muna 2017. Inorayirwawo kuti iite hurumende dzisingabatsiri (chorea) muhosha yaHuntington.
Austedo inokonzerwa nemakemikari neXenazine asi kubudirira kwayo kunogara kwenguva yakareba. Nekudaro, Austedo inowanzotarisirwa kutorwa kamwe kana kaviri pazuva, nepo Xenazine inowanzomirirwa kutorwa katatu pazuva.
Austedo yakaratidza kubudirira mukuderedza zviratidzo zveKorea, asi saHenazine, iyi mishonga inouya neshoko rakasimba-izwi rinoratidza kuti haringafaniri kushandiswa kune vanhu vane HD vane kutambura kwekuora mwoyo kana pfungwa dzekuzviuraya, sezvo zvingawedzere manzwiro avo.
Antipsychotic Mishonga
Antipsychotic mishonga, iyo inonziwo neuroleptics, dzimwe nguva inorayirwa kuti iite chorea. Iyi inoshandiswa kushandiswa kwemishonga yemishonga, zvinoreva kuti FDA haina kubvumirana nemishonga iyi zvakananga nekuda kwechinangwa ichi; zvisinei, zvimwe zvacho zvakaratidza zvimwe zvingabatsire munharaunda iyi.
Mitsva yekutsvakurudza inosiyana, asi inypical antipsychotics inowanzoshandiswa kurapa HD inosanganisira Zyprexa (olanzapine), Risperdal (risperidone), uye Seroquel (quetiapine). Vakura antipsychotics yakadai seHaldol (haloperidol) uye Clozaril (clozapine) inorayirwawo asi inogona kuve nemigumisiro yekudengenyeka uye tardive dyskinesia, zvose zviri zviviri zvinokonzera dzimwe mhando dzisingabatsiri uye zvingadaro zvisingabatsiri.
Kuwedzeresa, mamwe mishonga inopesana nemishonga yakaoma seAbilify (aripiprazole) yakaratidza kubudirira mukuderedza zviratidzo zvekuora mwoyo muHDH, pamwe nekuvandudza cognition.
Antipsychotics inoshandiswa dzimwe nguva nechinangwa chokuderedza zvinetso zvinopesana (zvakadai sechisimba) zvinogona kukura muHD; zvisinei, kune huwandu hunogona kuve nemigumisiro nekushandiswa kwe antipsychotics, saka kungwarira kunofanirwa.
Symmetrel
Tsvakurudzo pamusoro pekubudirira kweSymetmet (amantadine) yakaratidza migumisiro inopesana. Symmetrel isiri yemishonga inoshandiswa kugadzirisa kudengenyeka kusinganzwisisiki kunowanzoitika muhosha yaPacinson , saka chinangwa chayo muH HD chiratidzo che chorea. Inoratidzika inobatsira kune vamwe vanhu vane HD.
SSRIs
Kusarura serotonin reuptake inhibitor (SSRI) inodzvinyirira mishonga inorayirwa pane dzimwe nguva kubata chirwere nekudzvanyirira uye kumanikidzwa dzimwe nguva kune avo vanorarama neHD. Sezvimwe nemimwe mishonga, kubudirira kunosiyana.
Maitiro Anodzivirira
Mafungiro emafungiro akafanana neDepakote (divalproex) anogona kushandiswa kutarisa kuchinja kwakakura mumanzwiro anokwanisa kufambidzana neHD, pamwe nekudzvinyirira, kusagadzikana, uye kuvhara-zvinokonzera zviratidzo.
Mimwe Mishonga
Mukupindura kune zviratidzo zvakasiyana-siyana izvo murwere anoudza kuna chiremba wavo, mamwe mishonga inogonawo kurairwa kutarisa nyaya idzi. Semuenzaniso, kana kusuruvara nekuzvidya mwoyo ndizvo zvinonyanya kukosha muHD, chiremba anowanzomira mishonga kuti inorwisana navo. Nokudaro, zvinokosha kuti uzarurire neboka rako rehutano uye uvazivise ivo nezvezvinhu zvose zvinokuvhiringidza. Vangave vane sarudzo iyo ichavandudza mamiriro ako ezvinhu.
Zvisiri-Zvinodhaka Zvinoshandiswa
Sezvo kushandiswa kwemishonga panguva ino kuchikwanisa kuedza kuronga zviratidzo zvakananga muHD, mamwe maitiro asingabatsiri ezvinodhaka anokurudzirwa.
Kutaura uye Kutaura Mutauro
Kutaura uye mutauro wemapurisa anogona kushanda newe kuti ubatsire mukukurukura zvido zvako uye zvaunofarira. Zvimwe kudzidzira zvinogona kukubatsira iwe kusimbisa rurimi rwako nemumhutu wemuromo kuti urambe uchingoshanda iwe kwenguva yakareba.
Vatauriri vekutaura vanogonawo kuongorora mano ako ekugwinya uye kutsanangura kuti zvipi kana zvigadziro zvichave zvakakunakira iwe. Izvi zvinogona kukosha kubva, sezvo chirwere chinopfuurira, zvingava zvakaoma kumedza kudya kana mvura pasina kukwira.
Physical and Occupational Therapy
Kurapa kwepanyama uye kurapwa kwebasa kunogona kukubatsira nenzira dzakawanda. Muzvikamu zvekutanga zveHD, chirwere chepanyama chinogona kubatsira kuvandudza nekuchengetedza zvakakwana simba uye kushanda. Sezvo HD ichifambira mberi, zvigadzirwa zvinogona kurongedzwa uye zvakagadzirirwa kune zvaunoda, uye purogiramu yekuita pamba ingagadzirirwa kuwedzera hutano hwepanyama.
Mumwe mushandi wepamberi anogona kushanda newe pakugadzirisa nzira yakanakisisa yekuita mabasa ehupenyu hwezuva nezuva , sekushambidza uye kupfeka. Occupational therapists inogonawo kuona zviratidzo zvepfungwa , nechinangwa chekuchengetedza unyanzvi hwako hwekuziva.
Vanachiremba vanogonawo kushanda nevatarisi vako sezvo chirwere chinowedzera kuvabatsira kuziva kuti zvakanaka sei kukutarisira iwe.
Kudzidzira muviri
Kudzidzira muviri kwakave kwakanyatsobatana nehutu hwakasimba-kana kunyange hunovandudzika-ruzivo rwekuziva muzvirwere zvakawanda zvinokonzera kuora mwoyo, uye izvi zvinotenderera kune HD zvakare. Kutsvakurudza kwakaratidza kuti mazinga epamusoro ekurovedza muviri inofananidzira zvidzidzo zviri nani pamusoro pechiratidzo chekuziva uye kuvandudzwa kwezuva nezuva.
Psychotherapy / Support Counseling
Kutaura nechiremba wehutano hupanocial social kana kuti wepfungwa dzepfungwa anogona kuva yakakosha apo iwe uchigadzirisa kuchinja uko HD kunounza uye kuongorora mazano ako ekukunda. Kutaura kurapa kunogona kubatsirawo kune vakaroorana kana vashandi pamwe chete, pamwe nevana nevemhuri.
HD inounza kuchinja kukuru kune unhu hwekushanda kwako, uye inogona kukonzera kunetseka mumhuri dzemhuri pamusoro pengozi yavo yekuvandudza HD sezvo yakaparidzirwa vana. Mushonga unogona kukubatsira iwe nemhuri yako kushanda kuburikidza nekuchinja kuri kuitika, chizvarwa chehutachiwana hweHD, uye kukubatanidza nemari munharaunda yako uye neimba yako.
Creative Therapies
Dzimwe nzira dzinogona kubatsirawo avo vanogara neHD. Semuenzaniso, mimhanzi , unyanzvi, uye mishonga yemitambo zvose zvakashandiswa. Kunyange zvazvo vasingazoshanduki zviratidzo zveHD, vanogona kuchinja hupenyu huri nani nekuvandudza hupenyu hwehupenyu.
Dietitian Services
Kudya kudya kwakanaka kunokosha kwatiri tose, uye kunyanya kana uri kurwisana neHD. Kuvimbisa kuti muviri wako uri kuwana mishonga yakakodzera inobatsira kunogona kubatsira kuchengetedza simba rako. Izvi zvinogona kuva zvakaoma, kunyanya sezvo HD inofambira mberi, saka unogona kubatsirwa ne rubatsiro kubva kune anodhadhari wezvokudya.
Shoko Rinobva
Chinonyanya kukosha, vanhu vane HD nemhuri dzavo vane ngozi yekuzviparadzanisa. Ziva kuti kune zvigadziro uye rubatsiro runowanikwa kukukurudzira uye kukubatsira kuti uone matanho ako anotevera. Kana iwe usina chokwadi chekuita kana kuti unoda rubatsiro, Huntington's Disease Society of America ine zvitsauko zvepamunharaunda pamwe nemapoka ekutsigira muIndaneti zvinogona kukukurudzira, kupindura mibvunzo yako kana kufamba nemwi kana kungova nzeve yekuteerera sezvauri kurarama HD.
> Sources:
> Arora, G. (2015). Kutarisira Kushungurudzika muHurtington Dendaase. http://hdsa.org/wp-content/uploads/2015/07/Managing-Aggression-in-HD_Garima-Arora_ver005.pdf
> Coppen, E. uye Roos, R. (2016). Nzira dzepamusoro dzehutachiona hwepamusoro dzekutapudza Chorea muHurtington's Disease. Zvinodhaka , 77 (1), pp.29-46. 10.1007 / s40265-016-0670-4
> Dale, M. uye van Duijn, E. (2015). Kuzvidya mwoyo muHurtington. Journal of Neuropsychiatry uye Clinical Neurosciences , 27 (4), pp.262-271.
> Wallace M, Downing N, Lourens S, et al. Pane Chekubatana Kwechiitiko Chekuita neBongo Volume, Maitiro, uye Zuva Nezuva Rinoshanda? A Cross Crossal Design in Prodromal uye Early Huntington Disease. PLoS Currents . 2016;
> Wetzel HH, Gehl CR, Dellefave L, et al. Kuda kuzviuraya muhutano hweHuntington: Basa rekuvhiringidza. Psychiatry research . 2011; 188 (3): 372-376. doi: 10.1016 / j.psychres.2011.05.006.