Lumbrokinase inyme enzyme yakagadzirwa kubva kuLumbricus rubellus, mhando dzevhu. Yakatengeswa muhuwandu hwezvokudya zvekudya, inorondedzerwa se-fibrinolytic enzyme (chinhu chinokurudzira kuparara kwe fibrinogen, puroteni inobatanidzwa mukugadzirwa kweropa rega). Kuwedzera ne lumbrokinase kunofungidzirwa kupa huwandu hwehutano hunobatsira, kusanganisira kuwedzera hutano hwemwoyo uye kubatsira mukudzivirira chirwere nekurwisa ropa.
Zvishandiso
Vatsigiri vanoratidza kuti lumbrokinase inogona kubatsira nemamiriro ezvinhu anotevera ehutano:
Batsirwa
Kusvika ikozvino, tsvakurudzo pamusoro pehutano hwe lumbrokinase inogumira. Kunyange zvakadaro, pane humwe uchapupu hwokuti hunoratidza chivimbiso chekurapwa kwemamwe mamiriro ezvinhu. Heino tarisiro pane zvimwe zvitsva pane zvingangobatsira:
1) Moyo Utano
Lumbrokinase inogona kubatsira mukurapa angina, maererano nekutanga kwekudzidza yakabudiswa mu Journal of Alternative uye Complementary Medicine muna 2009. Kuongorora, vatsvakurudzi vakapa vanhu gumi vane chirwere chemwoyo uye angina mwedzi umwe wekurapa ne lumbrokinase (mukuwedzera kusvika pakuchengetedzwa kwavo kwakatarwa). Nokuguma kwekudzidza, zviratidzo zveAngina zvakanga zvavandudzwa mune vatanhatu vevatatu.
Uyezve, chidzidzo chekutanga chekutanga chinoparidzirwa mumutauro weChina chinoitwa Acta Pharmaceutica Sinica muna 2006 chakawana kuti lumbrokinase inogona kuchengetedza utano hwemoyo.
Mune miedzo pamakonzo, vanyori vekudzidza vakagadzirisa kuti lumbrokinase inogona kudzivirira kurwisa myocardial ischemia (mamiriro akaratidzwa nekuvharwa kweeronary arteries uye kuderera kweropa kunopinda mumwoyo).
2) Kurwisa
Kutsvakurudza kwepakutanga kunoratidza kuti lumbrokinase inogona kubatsira kubvisa kupora. Mune chidzidzo che2013 chakabudiswa muChina Medical Journal , somuenzaniso, vanhu 310 vari muchipatara ne ischemic stroke (rudzi rwechirwere chinowanzoitika kana arteri muuropi ichidziviswa) yakarapwa nehutachiona hwechirwere kana chirwere chinowedzera pamwe ne lumbrokinase capsules kune imwe gore.
Nekuguma kwekudzidza, boka rinogamuchira kurapa kwe lumbrokinase rakanga rine zvishoma zvinyorwa zveschemic.
Mune chidzidzo che2008 kubva kuEuropean Journal of Pharmacology , kuongororwa kwemasero evanhu kwakagadzirisa kuti lumbrokinase inogona kubatsira kurindira kusagadzikana ischemia. (Chiitiko chinoratidzwa nehuwandu hwekuyerera kweropa kusvika muuropi, cerebral ischemia inogona kuderedza uropi hwehurogi uye, zvakare, inotungamirira kurwara.) Chidzidzo chacho chakawana kuti lumbrokinase inogona kurwisa utachiona ischemia muchikamu nekudzivisa kuumbwa kweropa.
Mukuwedzera, chidzidzo chiduku chakabudiswa muCliniki Hemorheology uye Microcirculation muna 2000 chakawana kuti lumbrokinase inogona kubatsira mukurapa kwechirwere chinonzi infarction (rudzi rweuschemic stroke inokonzerwa nekuumbwa kweropa mukati meuropi).
Nokuda kwekudzidza, vanhu 31 vane cerebral infarction vaibatwa ne lumbrokinase, asi vamwe varwere makumi maviri vakagoverwa kuboka rinodzora. Migumisiro yakaratidza kuti lumbrokinase inogona kubatsira kubata cerebral infarction muchikamu nekuderedza fibrinogen.
3) Chirwere cheshuga
Chidzidzo chezvipfuwo-chakabudiswa muDhiabetes Research and Clinical Practice muna 2013 chinoratidza kuti lumbrokinase inogona kubatsira kurwisa chirwere cheshuga nephropathy (chirwere chepfungwa chinokonzerwa nechikamu chisina kunaka chekushaya chirwere cheshuga nekudzvinyirirwa kweropa ).
Mune chiitiko chinokonzera rats, chirwere cheshuga chakacherechedza kuti kurapa ne lumbrokinase kwakabatsira kudzivirira kurwisana nechirwere cheshuga nephropathy (zvichida kuburikidza nekukanganisa mamwe enzyme inofungidzirwa kuti inobatanidzwa mune zvinetso zvepimpano zvinosanganiswa nemamiriro aya).
Migumisiro Yacho Inogona Kuitika
Sezvo zvidzidzo zvishomanana zvakaedza kuve nemigumisiro ye lumbrokinase muvanhu, zvakakurumidza kutaurira kana lumbrokinase yakachengeteka kwenguva refu kana nguva dzose kushandiswa. Vakadzi vane pamuviri, vanaamai vanoyamwisa, uye vana havafaniri kutora lumbrokinase.
Panewo kumwe kunetseka kuti lumbrokinase inogona kukonzera mimwe migumisiro yechirwere, kusanganisira kuora mwoyo, kubvongodza, kurara, kuputika kweganda, uye zvinokonzera kugadzirisa.
Sezvo lumbrokinase inonzi inoputsa fibrinogen (iyo inodiwa kuumba ropa rinoputika), zvinongodaro kuti kuwedzera kunogona kukanganisa nehutano hwekuvhara uye kutungamirira kubuda ropa.
Vanhu vane mitemo inobatanidza nehuwandu hwehuwandu hwekubuda ropa haufaniri kutora lumbrokinase. Hazvifanirwi kutorwa kusati kwaitika kana kutevedza kushanda. Izvowo haifaniri kutorwa nemishonga, zvokudya zvinowedzera, kana kuti herbs ane ropa-rinopisa simba.
Zvakakosha kuchengetedza mupfungwa kuti zvidimbu hazvina kuongororwa kuchengetedzwa uye zvokudya zvekudya zvinowanzosaregererwa. Heano mamwe mazano pamusoro pekushandisa kudya kunowedzera zvakachengeteka.
The Bottom Line
Kunyange zvazvo kutsvakurudza kwepakutanga kuchifadza, pane kushayikwa kwezvikwereti zvekuchirapa-rudzi rwekutsvakurudza iwe unoda kuisa kuisa zvizere muhutano-zvichiratidza izvi. Kana iwe uchiri kufunga kuishandisa, zvakakosha kuti ubvunze chiremba wako kuti akurukure kana zvakakodzera uye zvakachengeteka kwauri uye kuongorora zvinowedzera uye zvakashata. Lumbrokinase haifaniri kushandiswa panzvimbo yekurapa kwakakwana kune mamiriro akaita sendima kana chirwere.
Kuti uwane rubatsiro mukuderedza dambudziko rako rekurohwa, zvinokosha kuti uchengetedze ropa rako uye cholesterol, tevera kudya kwakakwana, kurovedza muviri nguva dzose, uye usaputa. Zvimwe zvidzidzo zvinoratidza kuti vanhu vanodya teji yega, yehai yei, uye omega-3 fatty acids vanogona kunge vane ngozi shoma yekurohwa.
Sources:
> Cao YJ, Zhang X, Wang WH, et al. Oral fibrinogen-depleting agent wembrokinase yechipiri ischemic stroke kudzivirira: zvinokonzerwa ne-multicenter, randomized, parallel-group uye rinorongedzwa kliniki yekuedzwa. Chin Med J (Engl). 2013 Nov; 126 (21): 4060-5.
> Ji H, Wang L, Bi H, et al. Nzira dze lumbrokinase mukuchengetedza kuberekwa ischemia. Eur J Pharmacol. 2008 Aug 20; 590 (1-3): 281-9.
Jin L, Jin H, Zhang G, Xu G. Kuchinja mukubatanidza uye mishonga ye plasminogen activator mushure mekurapwa kweperectional infarction ne lumbrokinase. Clin Hemorheol Microcirc. 2000; 23 (2-4): 213-8.
Kasim M, Kiat AA, Rohman MS, Hanifah Y, Kiat H. Kuvandudzwa kwemyocardial perfusion mumagariro angina pectoris nemuromo lumbrokinase: chirwere chekuongorora. J Altern Complement Med. 2009 May; 15 (5): 539-44.
Sun H, Ge N, Shao M, Cheng X, Li Y, Li S, Shen J. Lumbrokinase anochengetedza chirwere cheshuga nephropathy kuburikidza nekuraira kudengenyeka kwematokisi ekuwedzera muStreptozotocin-induced rats diabetes. Diabetes Res Clin Pract. 2013 Apr; 100 (1): 85-95.
Zvinonzwisisika: Mashoko anowanikwa pane ino yepaiti inoitirwa zvinangwa zvekudzidzisa chete uye haisi kutsiva mazano, kuongororwa kana kurapwa nechiremba ane chiremba. Hazvirevi kuvhara zvose zvinogona kumira, kushamwaridzana kwezvinodhaka, mamiriro ezvinhu kana zvinetso zvakashata. Iwe unofanirwa kutsvaga kurapwa nokukurumidza mune zvehutano kune chero hutano hwehutano uye bvunza chiremba wako usati washandisa mamwe mushonga kana kuita shanduko kune regimen yako.