Kana iwe uchirarama nemamiriro ezvinhu akaita sehasteoarthritis kana kuora mwoyo, unogona kunge watoziva kuti ingakanganisa sei zvimwe zvinhu zvehutano hwako, zvichiita kuti uite zvinhu zvakadai sekurema, kuoma kurara, uye kurwadziwa kusingaperi.
Imwe mishonga inonzi kuderedza kushungurudzika, arthritis, uye mamwe mamiriro ezviyo ndeyekuwedzera SAMe, inozivikanwawo seSAM-e, ademetionine, kana S-adenosylmethionine.
SAMe ndiyo yakagadzirwa nemakemikari anokonzerwa nemuviri kubva mumuviri kubva kune methionine (inokosha amino acid) uye adenosine triphosphate (iyo inogadzira magetsi).
SAMe haisi kuwanikwa nenzira yezvokudya. Muviri unowanzoita zvaunoda kuti utano huve nani, zvisinei, zvimwe zvirwere zvinotaura uye hutsika hwemashionine, folate, kana vitamini B12 dzinotendwa kuti dzinobatsira kudzikisa maSAMe.
Zvinofungidzirwa kuti SAMe inogona kubatsira kukurudzira kugadzirwa kwemakemikari anozivikanwa kutamba basa rinokosha mumhando dzakasiyana-siyana mumutumbi, zvakadai semafungiro ehutano, masimba ekudzivirira muviri, uye kurwadziwa kunzwisisika.
Sei Vanhu Vakatora Zvigadzirwa zveSAMe?
SAMe inowanzoshandiswa pane zvinotevera zvehutano:
- Kufunganya
- Kuora mwoyo
- Fibromyalgia
- Osteoarthritis
- Pain
- Premenstrual syndrome (PMS)
SAMe inonziwo kuwedzera kushanda kwepfungwa, kuwedzera hutano hutano , kunonoka kukwegura, uye kubatsira vanhu kusiya kusvuta.
Makomborero: Inogona Kubatsira Zvechokwadi here?
Hezvino tarisa zvimwe zvekutsvaga pamusoro pezvinobatsirika zveSAMe.
1) Osteoarthritis
SAMe inoratidza kuvimbiswa mukurapa kweosteoarthritis yemabvi kana hip. Zvinonzi kuderedza marwadzo uye kuva ne-anti-inflammatory properties, uye kumwe kutsvakurudza kunoratidza kuti inogona kukurudzira katetilage kugadzirisa.
Nokuda kwehupfumi hwakabudiswa muChonnrane Database yeUkuongorora kwakagadziriswa muna 2009, vatsvakurudzi vakatsvaga maitiro mana emakiriniki akabudiswa kare (aine 656 vatori vechikamu) uye akawana kuti kushandiswa kweSAMe kunogona kubatsira kuderedza marwadzo nekuvandudza basa kune vanhu vane osteoarthritis.
Sezvo kuongororwa kwemuedzo kwaive kwehutsika hwakashata, zvisinei, vanyori vekudzokorora vaona kuti izvi zvakawanikwa hazvina kukwana.
2) Kuora mwoyo
Mukuongorora kwekutsvakurudza kwakabudiswa muChonnrane Database yeUkuongorora kwakarongeka muna 2016, masayendisiti akaongorora mapiritsi masere emakirini akabudiswa akafananidzwa achifananidza SAMe kune antidipressants imipramine, desipramine, kana escitalopram, kana placebo.
SAMe yaive yakakwirira pane placebo iyo yakashandiswa nesarotonin reuptake inhibitor (SSRI) yakashandura (anti-depressants), asi uchapupu hwaifungidzirwa kuti hwakashata. Zvichienzaniswa nemipirinine, vashoma vanotora chikamu vakawana migumisiro yakaipa pavanorapwa nejecha reSAMe. SAMe yakanga isiri yakasiyana ne-placebo kana kuti zvinorwisa zvirwere zvakadai se imipramine kana escitalopram kana ishandiswa yoga.
Mukupedza kwavo, vanyori vekudzokorora vanotaura kuti kushandiswa kweSAMe kwekuora mwoyo kunofanirwa kuongororwa zvakare mune dzakawanda uye zvakanaka-zvakarongwa miedzo "yakapiwa kusavapo kwehupupuri hwepamusoro uye kusakwanisa kugadzirisa zvikonzero maererano nouchapupu huno."
3) Fibromyalgia
Mukutsvakurudza kwekutsvakurudza kwakabudiswa mu Journal of Complementary and Alternative Medicine muna 2010, masayendisiti akatarisa makumi manomwe emakiriniki akabudiswa kare akaongorora kushandiswa kwemarudzi akasiyana-siyana emishonga inobatanidza yekusingaperi kusuwa uye chirwere uye fibromyalgia.
Pamwe chete ne magnesium, L-carnitine, kugadziriswa, uye mhando dzakasiyana dzekufungisisa, vanyori vekudzokorora vanonzi SAMe pakati pemishonga ine mikana yakawanda yekutsvaga tsvakurudzo pamusoro pekubudirira kwavo maererano nemamiriro aya.
4) Chirwere Chirwere
SAMe inogona kuvandudza chiropa chinoshanda kune vanhu vane chirwere chechirwere chisingagumi, inoratidza kuongorora kwekutsvakurudza kwakabudiswa mupepanhau PLoS One muna 2015. Zvisinei, pakucherechedza 12 dzakambobudiswa zviyero zvemakirini zvakabatanidzwa mukudzokorora, vanyori vakaonawo kuti SAMe inogona kunge isina zvishoma mukurapa kwehumwe hutachiona hwehutachiona hwakadai sehutachiona hepatitis uye cholestasis.
Migumisiro Yacho Inogona Kuitika
SAMe inogona kukonzera mimwe migumisiro yechirwere, kusanganisira kuzvidya mwoyo, kuvhiringidzika, kuora, muromo wakaoma, kuora musoro, kuora mwoyo, kusuruvara, gesi, shuga shoma yeropa, kusuruvara, kutya, kuputika kweganda, uye kurutsa. Zviyero zvakawanda zveSAM zvinogona kukonzera mania (mafungiro asina kukodzera). Panewo kumwe kunetseka kuti kushandiswa kweSAMe kunogona kuita kuti zvirwere zviitike kune vamwe vanhu.
Kana iwe une bipolar disorder, Lesch-Nyhan syndrome, chirwere chePalinson, kana zvimwe zvirwere, iwe unofanira kungoshandisa SAMe pasi pekutarisirwa kwehupi wehutano wehutano sezvo zvingawedzeredza zviratidzo.
Zvakakosha kucherechedza kuti panogona kunge kune njodzi pakubatanidza SAMe nemishonga kana zvimwe zvinowedzera. Iwe haufaniri kutora SAMe pamwe chete nevanorwara nehutachiona, mushonga wokukanganiswa, chirwere cheshuga, levodopa (L-dopa), L-tryptophan, mishonga inobata maitiro e serotonin, wort John's wort, kana mamwe mishonga kunze kwekuti uri kutariswa nehutano unyanzvi. SAMe inofanira kubviswa kwemavhiki masere isati yambovhiyiwa chirongwa.
Kuchengetedzwa kweSAMe kuvana, vakadzi vane pamuviri kana vakwegura, kana vanhu vane hono kana chirwere chechiropa hazvina kugadziriswa. Iwe unogona kuwana mazano ekushandisa zvishandiso zvakachengeteka , asi iwe unofanirwa kutaura neunotarisira iwe mukuru wekutanga usati watora SAMe kuzokurukura kana zvakakodzera kwauri. Ramba uchifunga kuti SAMe haifaniri kushandiswa sechinotsiva kurapwa kwakakwana.
Shoko Rinobva
Kurarama nehupi husingaperi huri nyore. Kunyange zvazvo dzimwe dzidzo dzichiratidza kuti SAMe inogona kupa zvimwe zvikomborero, hatigoni kuva yakasimba pamusoro pekubatana kusvikira paine yakagadzirirwa, zvikuru-scale clinical trials (rudzi rwekutsvakurudza waunoda kuona kuisa chizere chakazara mukurapa) .
Zvakakoshawo kuti uchengete mupfungwa kuti SAMe haifaniri kushandiswa pamwe chete kana munzvimbo yekurapa yakurudzirwa nachiremba wako. Kana uri kufunga nezvekuedza SAMe kuwedzera, iva nechokwadi kutaura nechiremba wako kuti uone kufambisa uye kubvuma uye kurukura kana zvakakodzera kwauri.
> Sources:
> Galizia I, Oldani L, Macritchie K, et al. S-adenosyl Methionine (SAMe) yeDambudziko rekudengenyeka muAdults. Cochrane Database Syst Rev. 2016 Oct 10; 10: CD011286.
> Guo T, Chang L, Xiao Y, Liu Q. S-adenosyl-L-methionine yekurapa kwechirwere chechirwere chechirwere: Ongororo yeChirongwa uye Meta-Kuongorora. PLoS One. 2015 Mar 16; 10 (3): e0122124.
> Porter NS, Jason LA, Boulton A, Bothne N, Coleman B. Nzira Dzakasiyana-siyana dzeMishonga Dzinoshandiswa Mukurapa uye Kutungamirirwa kweMyalgic Encephalomyelitis / Chronic Fatigue Syndrome uye Fibromyalgia. J Altern Complement Med. 2010 Mar; 16 (3): 235-49.
Zvinonzwisisika: Mashoko anowanikwa pane ino yepaiti inoitirwa zvinangwa zvekudzidzisa chete uye haisi kutsiva mazano, kuongororwa kana kurapwa nechiremba ane chiremba. Hazvirevi kuvhara zvose zvinogona kumira, kushamwaridzana kwezvinodhaka, mamiriro ezvinhu kana zvinetso zvakashata. Iwe unofanirwa kutsvaga kurapwa nokukurumidza mune zvehutano kune chero hutano hwehutano uye bvunza chiremba wako usati washandisa mamwe mushonga kana kuita shanduko kune regimen yako.