Iyo synovium, iyo inonziwo synovial membrane, ndiyo nyuchi dzakapfava dzinotenderera nzvimbo dzezvinyorwa zvemaarthrodial, tendon sheaths, uye bursae. Iyo synovium inotenderera mukati rose mukati memubatanidzwa, kunze kwekuti paine chibatanidzi chakabatanidzwa nekartilage . Iyo synovium ine chinyorwa chekunze (pfungwa dzomukati) uye mukati mukati (intima). Masero eIntima anonzi synoviocytes.
Kune marudzi maviri e synoviocytes, aina A (macrophage-yakagadzirwa) uye rudzi B (fibroblast-yakagadzirwa). Izvo zvinyorwa zvinosanganisira intra-articular (mukati memakabati) midziyo, yakadai semidziyo yeropa nemidziyo ye lymphatic, uye nerve. Pasi pemakamuri e synoviocytes, pane zvimwe zvinonzi adipose tissue kana fibrous tissue. Iyo synovium ndiyo iyo synovial fluid inobudiswa, iyo inogadzirisa uye inosimudzira chikafu nemapfupa mukati memubatanidzwa capsule.
Synovium muRheumatoid Arthritis
Kungofanana nezvimwe zvirwere zvakawanda zverheumatic, rheumatoid arthritis chirwere chemoto . Mune chirwere chinotapukira kana chimiro, muviri wemunhu, uyo unowanzobatsira kuchengetedza muviri kubva kune hutachiona uye zvirwere, kurwisa humwe hutachiona hunoti zvikonzero zvisingazivikanwi. Mu rheumatoid arthritis, immune system system dzinoenda ku synovium uye dzinotanga kuvhiringidza (synovitis). Izvo zvinoputika zvinoratidzwa nekupararira kwemasero e-synovial, kuwedzera vascularization, uye kupindira kwezviviri nemasero anopisa, kusanganisira lymphocytes, masero eplasma, uye macrophages akashandiswa.
Izvi zvinoratidzika sezviratidzo zvinowanzoitwa rheumatoid arthritis- kutonhora , kubwinya, kuzvimba, uye kurwadziwa.
Sezvo rheumatoid arthritis inofambira mberi, inonzi synovium inopinda inoparadza uye inoparadza gumbo uye bone rekubatana. Misungo inopoteredza, ligaments, uye tendon iyo inotsigira nekusimudzira kubatana inoita simba uye haigone kushanda zvakanaka.
Izvi zvinokonzera marwadzo akabatana pamwe nekuvhiringidza pamwe chete zvinowanzoonekwa kuvanhu vane rheumatoid arthritis. Kunzwisisa zvinoitika ku synovium mu rheumatoid arthritis kunokubatsira kunzwisisa zviratidzo uye chirwere chakakomba.
Mishonga Inotarirwa Inopera Synovium - Iri Kuuya Here?
Pakave nekufarira pakati pevatsvakurudzi pamusoro pekugadzirwa kwemishonga yakasiyana-siyana ye rheumatoid arthritis. Zvichida, zvinodhaka zvinogona kutarisa synovium nekuwedzerwa kubudirira kana ichinge yakaderera kushandiswa kwehutachiona. Kana izvi zvikaitika-zvichikwanisa, mafungiro ekufungidzira angangodaro akaendeswa ku synovium, zvichibvumira kuongororwa kwekushanda synovitis muzvikamu zvakawanda. Nepo pave nekufambira mberi munharaunda iyi, imwe svondo ye synovial haifaniri kuwanikwa.
> Sources:
> Freemont, Anthony J. The Pathophysiology yeCarlage uye Synovium. British Journal yeRheumatology. 1996; 35 (suppl.3): 10-13.
> Garrood T. naPitzalis C. Targeting the Inflamed Synovium. Kutsvaka Zvakajeka. Arthritis uye Rheumatism. April 2006.
> Kelley's Textbook of Rheumatology. Ninth edition. Firestein et al. Biology yeHoward Joint. Mapeji 8-10.
> O'Connell, John X., MB FRCPC. Pathology yeSynovium. American Journal of Clinical Pathology.
> Smith, Malcolm D. The Normal Synovium. The Open Rheumatology Journal. 2011; 5: 100-106.