IIiyo Maori Hormones Anodzora Kufurirwa Kweropa
Iyo renin-angiotensin system iboka rehomoni dzinobatana dzinoita pamwe kuti dzigadzirise ropa rinopisa. Inonzi chirongwa nokuti chikamu chimwe nechimwe chinokurudzira zvimwe zvikamu uye zvose zvinodiwa kuti yose ishande zvakanaka. Iyo renin-angiotensin system, kushanda pamwe chete neitsvo, ndiyo inonyanya kukosha yomuviri kwenguva refu yeropa rekugadzirisa urongwa hwehutano.
Kunyange zvazvo kwenguva pfupi kushandiswa kweropa kuchinjwa kunokonzerwa nemhando dzakasiyana-siyana, zvinenge zvese zvinogara kwenguva refu kuchinja kweropa zvinokonzerwa neitsvo uye renin-angiotensin system.
Sangano Renin-Angiotensin Rinoshanda Sei?
Nhengo dzinokosha dze renin-angiotensin system ndezvekuti:
- Renin
- Angiotensin I
- Angiotensin II
- Angiotensin Converting Enzyme (ACE)
Kana kudzvinyirirwa kweropa kunodonha nechikonzero chero chipi zvacho, masero anokosha ari muinso anoona kuchinja uye kusunungura renin muropa. Renin pachayo haaiti chaizvo kukanganiswa kweropa . Pane kudaro, inofamba-famba uye inoshandura maitiro asina kushandiswa e-angiotensin achiita angiotensin I. Aya maitiro asingashandisi eangiotensin, anobudiswa nechiropa, haagoni kukwanisa kuchinja ropa kusvikira renin ichivashandura kuva angiotensin I.
Angiotensin Ndinokwanisa kuchinja kuwedzera kweropa kune imwe nguva, asi haisi yakakwana kukonzera kuchinja kukuru.
Pane kudaro, akawanda angiotensin Ini ndinoshandurwa kuva angiotensin II, hormone yakawanda zvikuru iyo inokonzera kuchinja kukuru kweropa. Ichi chechipiri kutendeuka kunowanzoitika mumapapu kuburikidza nechiito cheimwe imwe molecule inonzi angiotensin-kuchinja enzyme (ACE). (Uku kutendeuka kunogona kupfigirwa nemishonga inonzi ACE Inhibitors, iyo inokosha yepamusoro yehuwandu hwemishonga yemishonga .)
Angiotensin II ihomoni yakasimba uye inogona kuita zvakananga mumidziyo yeropa kuwedzerwa ropa. Iine rimwe basa rinokosha pamwe-kukurudzira kusunungurwa kwealdosterone. Aldosterone iyi vasoconstrictor ine simba zvikuru inokonzera kukura kukuru kweropa asi asi inonyanya kukosha nokuti inogona kuchinja basa rekutanga rekutsvaga kwetsvo. Aldosterone inokonzera kuti itsvo dzichengetedze munyu nemvura, iyo inopfuura nguva inowedzera huwandu hwemvura mumutumbi. Izvi kuwedzera, zvakare, kunomutsa kuwedzera kweropa.
Pashure penguva yakati, angiotensin I, angiotensin II, uye aldosterone dzakaputsika mune mamwe mamolekyu. Iyo renin-angiotensin system, seyakazara, inopindirana kumapfupi maviri uye kwenguva refu ekusiyana kweropa. Inoshandiswa nekudengenyeka kunononoka muropa, sezvakaita izvo zvinoitika mushure mekurasikirwa kweropa, asiwo zvinokurudzirwa nediki, kuderera kunokonzerwa kwehuwandu hwemagetsi.
Sekugara kwenguva refu mutongi wehushani weropa, renin-angiotensin system inogara iri yekutanga yekutanga yebasa, uye inoshanda chaizvo yakafanana negasi rinotsika yemotokari. Nguva dzose kushushikana pamusoro pegasi inoshandiswa kunofanirwa kuchengetedza motokari kuenda mberi, kunyange apo iwe unongoda kuenda imwe chete.
Kana iwe uchida, zvakadaro, iwe unogona kuisa pasi pedal pasi kamwe-kamwe kuitira kuti kukurumidze kukurumidza. Saizvozvowo, kushanda nguva dzose muine renin-angiotensin system inochengetedza kuwedzera kweropa kudarika kwenguva refu, asi kuputika kwechimbichimbi kunogona kuitika kana kukurumidza kupindura kuchidiwa.
Sei Chirongwa cheRinin-Angiotensin Chinokosha Mukuderedzwa Kweropa Rakawanda?
Mapepa ezvesayenzi, mharidzo yehurukuro, uye kunyange mabhuku ose ezvinyorwa akanyorwa pamusoro pekukosha kwenhain-angiotensin system muropa rekushandisa mutemo. Iyi inzvimbo yakasimba yekutsvakurudza iyo iri kutevedzwa nevevamwe vezvesayenzi vane tarenda munyika yose.
Iyo renin-angiotensin system inotarisisa zvikuru nokuti inozivikanwa kuti inokosha inogona kutibatsira kunzwisisa:
- Chikonzero nei vanhu vachikudzwa nehutano hwemhepo pane zvose
- Chikonzero nei vamwe vanhu vasingabvumi zvakanaka kune zvinoenderana nepamusoro yehutano hwehutano hwekurapa
- Chikonzero nei vamwe vanhu vane huwandu hwehutano hwemhepo vachiwedzera matambudziko kupfuura vamwe
Semuenzaniso, varwere veAfrica-America vane huwandu hwehutano hwemumakumbo kakawanda havatauri zvakare kuACE inhibitors semamwe mishonga. Izvi zvingangodaro nokuti veAfrica -America vane maitiro akasiyana-siyana emabasa avo mune renin-angiotensin system, izvo zvinoita kuti vasanyanya kunyatsoona zvinodhaka zvinoshanda nekuvhara hurongwa.
Nhamba dzakawanda dzehutano hwepamusoro yehutano hwehutachiona dzakagadzirwa sechikonzero chakakwana chekunzwisisa kwatinoita renin-angiotensin system. Pamwe neACE inhibitors, iyo inomisa kutendeuka kweaniotensin I kusvika angiotensin II, mamwe mishonga inoshanda nekutsvaga zvikamu zvakasiyana zvehurongwa. Angiotensin receptor blockers (ARBs) , somuenzaniso, kudzivirira angiotensin I uye angiotensin II kubva kumisungo kumitsipa yeropa uye zvichiita vasoconstriction.
Kunyange zvazvo tsanangudzo dzakanakisisa dze renin-angiotensin system dzichiri kuwanikwa, kunzwisisa kwatinoita nzira iyi inokosha yekugadzirisa kwakatotungamirira kukurudzirwa kwezvikamu zvakasiyana-siyana zvehutano hwehutano hweropa uye kunzwisisa kwakanakisisa kwokuti ungatevedzera sei kuwedzera kweropa rehupenyu pamusoro penguva refu.