Pane imwe nguva kana imwe, isu tose tave nechinangwa chakanaka pamusoro pemishonga erectile isingaiti seyero sildenafil (Viagra) uye tadalafil (Cialis). Asi kunetseka sezvatingaita, mishonga iyi inoshamisa chaizvo inobatsira pakubatsira varume vane zvepabonde uye erectile dysfunction. Kutsvakurudza kutsva nemakiriniki emitemo zvinoratidza imwezve kushandiswa kwemishonga iyi: co-administration nemishonga yakafanana nemafinari (Proscar) kana dutasteride (Avodart), iyo iri 5-alpha-reductase inhibitors inoshandiswa kurapa benign prostatic hyperplasia (BPH).
Kunyanya kunyanya, 5-alpha-reductase inhibitors uye alpha blockers, imwe mhando yeBPH mishonga, ita nhamba pane libido yemunhu uye kukwanisa kuchengeta erection - chinhu chakaipa chinopesana ne erectile dysfunction meds seCialis. Uye zvakare, muna 2011, FDA yakagamuchira Cialis kuti irapwe zviratidzo zveBPH, zvakare (funga kunetseka nekuzora). Saka, Cialis inobatsira zvikuru kune avo vane BPH!
Chii Chinonzi Benign Prostatic Hyperplasia (BPH)?
Kana iwe uine BPH, zvichida haufaniri kuiswa sumo kune zvisingakanganisi, zvinoshungurudza uye dzimwe nguva zviratidzo zvakakomba zvikuru. Zvisinei, isu tose tisina uninitiated, heino mamwe mashoko pamusoro pechiitiko ichi.
Benign prostatic hyperplasia inoratidzika (isina kuchinja) kuwedzera kweprostate gland. Mune varume, prostate inoita semen. Mune varume vane BPH, prostate inogona kuva yakakura katatu uye inokonzera kuvhiringidza kwekuvhunga. Yezvinyorwa, prostate inoratidzika yakagadzirwa nemafungiro akakomberedza urethra kana "pee" tube; hupfeti inogara pasi pechipfuva.
Kunyange zvazvo kenza yeprotate inosanganisira hypertrophy uye hyperplasia uye dzakawanda zviratidzo zvakafanana zveBPH, BPH haisi kenza. Ihwo hutsika hunoita iyo varume vakawanda vane makore makumi mashanu kana kupfuura vakamboziva pane imwe nguva. Uyezve, BPH inogona kunge isingatauri mungozi yekuwedzera kenza yeprostate.
Mune varume vakawanda, BPH haina kumira uye inokonzera zviratidzo zvisingaoneki Nezvechitatu chevarume veAmerica, zvisinei, vanogona kuona zviratidzo zvekutanga zvinotevera:
- Kuramba uchikurudzira kurinate (urinary frequency) kunyanya usiku
- Inonyorera urwizi runotanga runotanga uye inomira
- Kunzwa kuti iwe uchiri kukwanisa kutora kunyange mushure mokunge iwe watopedza kurinha
- Dambudziko rinotanga urine stream (hesitancy)
- A kubata ropa mumuyo
Nokufamba kwenguva, BPH inogona kutungamirira kune zvinetso zvakakomba zvakadai sekuvhiringidza urwere, zvirwere, uye kuora kwechirwere. (Kuvhiringidzika kunokonzerwa nehutachiona hwehutachiona hunogona kukonzera urine kuchengetedza iyo inokuvadza itsvo neshungu.)
Kurapa kwokutanga kweBPH ndiko kurapwa nekuvhiya ( TURP ) yakachengeterwa vanhu vanokundikana mishonga inorapwa. Varume vane zviratidzo zveBPH vanowanzogamuchira miviri miviri yemishonga: alpha blockers (funga terazosin kana doxazosin) uye 5-alpha reductase inhibitors seProscar uye Avodart inotaurwa pamusoro apa.
Muverengi akachenjera angaona kuti mhando mbiri dzemishonga yeBPH dzine alpha mumazita avo; zvisinei, nzira dzezvinodhaka izvi dzakasiyana zvachose. Alpha-blockers inonatsa marara mushure mutsvuku uye hupfeti kuitira kuti uwedzere kugadzirisa urini uye kubvisa kukanganiswa kwekuvhunga. Izvo, 5-alpha-reductase inhibitor inotarisa mahomoni ekudzivirira kweBPH uye kwete kungobatsira pakubhururuka kwekuvhenekera, asi, kana yakatorwa kwenguva yakakwana, inogona kunyatsopedza prostate uye inokurumidza kudiwa kwekuvhiyiwa.
Kuwedzera Cialis ku Mix
Pamusana pezvikonzero zvatinogona zvose tinozviziva, kunyunyuta kukuru pakati pevarume vakawanda vanotora chirwere neA alpha blockers, 5-alpha-reductase inhibitors kana kuti zvose ndeyekuti mu5 kusvika ku15 muzana yegents yakadaro inoshambadza ne erectile basa, libido, uye ejaculation. Kuti udzivise chiitiko ichi chakaipa chisingadiwi, urologists uye vanachiremba vanoita zvekutanga vanoedza kuwedzera kuwedzera kwekurapa kwemishonga. Uyezve, muna 2011, FDA yakanga yatobvumidza Cialis kurapa zviratidzo zveBPH, zvakare. Nokudaro, kune varume vane BPH, Cialis inoratidza kushanda zvakapetwa kaviri - inobatsira nekuzora, uye inobatsira ne erectile dysfunction.
Nenzira yakanaka, sayenzi inotsigira mutsika yekuwedzera zvinodhaka zvakanyanya zvakagadziriswa ne erectile kudzvinyirira kumitemo yemishonga yeBPH. Mumutambo mukuru wechirongwa-wekutonga wakatsigirwa naEli Lilly, vanoita zveCialis (kuenda mufananidzo), varume vanokwana 695 vakapiwa Cialis kana placebo kuwedzera kune 5-alpha reductase inhibitor finasteride.
Zvigumisiro zvaive zvakakurudzira chaizvo nekuwandisa zviitiko zvakakosha mune chido chepabonde, chirongwa chebasa, erectile basa uye kugutsikana kwepabonde kwakaonekwa kune avo vanotora Cialis vane mari yekugadzirisa mari. Uyezve, migumisiro yakaipa yaiva shoma uye inonzwisisika. Zvigumisiro zvakayerwa pa 4, 12 uye masvondo makumi matatu ekurapa vachishandisa bhuku remazita anonzi International Index of Erectile Function.
Sezvo zvinogona kutarisirwa kubva kune zvidzidzo zvakawanda kushandisa mari huru yeFarma, kutsvakurudza kugadzirisa kwekudzidza uku kwaive kwakasimba. Kunze kwezvinokonzerwa ne-placebo, zvingakwanisi zvekudzidza uku zvinosanganisira kusavimbiswa kwakavimbiswa kuti International Index ye Erectile Function yakashanda pakuyera kuchenesa uye kusagadzikana kwechirwere uye nguva shomanana yekurapa. Nenzira, vatsvakurudzi vaitarisa chete Cialis co-administration ne 5-alpha-reductase inhibitor, kwete alpha-blocker, zvakare.
Closing Thoughts
Kana iwe kana mumwe munhu waunoda ari kutarisana nehutano hwepabonde kune mamwe madhiragi eBPH semafinariro uye haasati ari paCialis, iva nechokwadi chekuudza chiremba wako wekutanga kana kuti urologist. Kuwedzerwa kweCialis pamutano wako wakachengeteka uye kunonzwisisika uye kunofanira kubatsira nehupenyu hwako hwepabonde uye zviratidzo zveBPH pachako.
Pamusoro pemashoko akafanana, pamusana pemigumisiro yaro yemasikironi, pasi-dose mari inotengesa mari inotengeswawo sePropecia, mushonga unopiwa nokuda kwekubvambura bvudzi. Kunyange zvazvo vanhu vanowanzozotora Propecia varume vaduku vane mikana yeErectile inoshaya simba, uye Propecia inotapira dose kupfuura Proscar, Propecia inogonawo kupindira nekuita zvepabonde. Kana iwe uri kutora mari yekugadzirisa kuchengetedza bvudzi uye uine erectile dysfunction kana libidinal zvinetso, iva nechokwadi chekuudza iwe kurondedzera chiremba.
> Sources:
> "Kuita zvepabonde muvarume nechezasi kweUnited Urinary Symptoms and Prostatic Enlargement Secondary kwa Benign Prostatic Hyperplasia: Zvikamu zveMwedzi-6, Dhiviri-Chifufu, Chidzidzo Chekugadziriswa kweTadalafil Yakagadzwa neFinasteride" na S. > Glina > uye co- vanyori vakabudiswa mu Journal of Sexual Medicine (2014).
> Fode M, Sønksen J, McPhee SJ, Ohl DA. Kushungurudzwa kweTape Reproductive Tract. Muna: Hammer GD, McPhee SJ. eds. Pathophysiology of Disease: An Kutangira ku Clinical Medicine, Seventh Edition . New York, NY: McGraw-Hill; 2013. Yakapera ka121/2015.