Zvikanganiso Mukupinduka Kunogona Kuumba "Mutant" Viruses Kurwisa neHIV Kuchengetedzwa
Kushandiswa kwemishonga yeHIV kunongorondedzerwa sekuchinja kwechimiro chetachiwana hweHIV, izvo zvinogona kuita kuti zvimwe zvirwere zvive zvakakwana kana zvakakwana kudzivirira mishonga inorwisa mabhakitiriya . Sezvo vanhu vakawanda vezvirwere zvinotenderera vachiri kukura, vanozopedzisira vava hutachiona hunotangira mukati me "viral pool." Kana izvi zvikaitika, munhu ane HIV ane mishonga inonyanya kushanda kusvikira kurapa kwapera.
Zvitsva zvinodhaka zvinodhaka zvinowedzera kukura nekudzivirira zvishoma nezvishoma, kunyange zvazvo kushaya mishonga yakakosha kunogona kuwedzera mungozi yekudzivirira kuburikidza nekubvumira utachiona (kusanganisira mavairasi anoshandura) kuti udzoke usina kumira.
Nei Kutapukira kweHIV kuchiitika?
Sezvo masero achibereka, vanoita makopi chaiwo ega, vachikura muchiverengo nekudzoka kwega kwega. Asi hutachiona hweHIV hunowanzoita zvikanganiso zvekunyora mazita, umo makopi acho anogadzirisa kana kusvibiswa. Kazhinji kacho kwete, izvi zvisingatauriki "mutant" zvinyorwa zvinokurumidza kufa.
Mune dzimwe nguva zvisingawaniki, zvisinei, zvinopesana zvinoitika. Panzvimbo pokufa, mamwe mavairasi anokwanisa kubudirira nokuti kushandura kwavo kwakagadzikana hakubvumi kuti mishonga yeHIV iite, inopinda kana kuvasunga. Saka kunyange zvazvo madhiragi aya akakwanisa kuuraya maronda epakutanga (anozivikanwa se "wild type" virus ), "mutauro" wakashandurwa unononoka kutora kuti uve dambudziko guru.
Genetic resistant inogonawo kuparadzirwa kubva kumunhu kusvika kune munhu kuburikidza nepabonde, kushandiswa kushandiswa kwemasero, kana kurongedza ropa-ku-ropa.
Kana kukanganisa kurapwa kuchiitika sechikonzero chekusagadzikana kwehutachiwana hweHIV, mamwe makirasi emishonga anoshandiswa kubhadhara zvakasiyana-siyana mukati mehutachiona hwemunhu.
Ona kuti kutapukirwa kweHIV zvinotanga sei mukudzidzisa , gumi-part slide show .
Nzira yekuona uye kugutsikana neHIV Zvinodhaka Kurwisa
Kune zviratidzo zveropa zviri nyore izvo zvinogona kuona kusagadzikana kweHIV uye kubatsira vanachiremba kuziva kuti mishonga inoshanda zvakanakisisa neiyo mutated virus.
Mhando mbiri dzekudzivirira kupikisa dzinonzi genotypic uye phenotypic testay dzinokwanisa kuziva, maererano, izvo zvinokonzera kuchinja kwezvinhu zvakagadzirwa uye kuwanda kwezvinhu izvi kuchinja kunopikisa.
- Nyanzvi dzeGenotypic dzinotsvaga mazita ekunyorwa kwetachiona, kutanga
kukurudzira ruzivo rwemajini uye zvino kutarisa kuona kuti chii chinoshanduka ipapo chinogona kuenzaniswa nehutachiona hwekutonga. Pathologist anogona kuenzanisa kuti mazinga ekudzivirira apo anobva pane imwe kana kuti mazita akawanda emagetsi akasiyana. Zvimwe zve "pfungwa imwe chete" zvakasiyana-siyana zvinosvika kumatunhu akakwirira ekudzivisa, asi vamwe vanoonekwa sevanhu vaduku uye vanongobatsira kuti varambe. - Phenotypic kuedza kunopesana nejenotypic test mukuti inotora hutachiona uye mumuviri inoratidzika kuhutano hwakasiyana hwemishonga yeHIV. Nokuita kudaro, inopa pathologist "chaiyo-nyika," uchapupu hunooneka hwezvinodhaka zvinodhaka.
Iyi miedzo inowanzoshandiswa kusarudza nzira yakanakisisa yekurapa mumutsetse wekutanga uye mishonga inotevera inoshandiswa muU.S. uye dzimwe nyika dzakapfuma. Zvisinei, mutengo we genotyping uye phenotyping inonzi inorambidzwa mune dzakawanda-dzinhara-dzimba dzisina urombo, uye kushandiswa zvishoma kunowanikwa kune vashandi vega.
Parizvino makambani akawanda einishuwarenzi muUnited States, vose vari voga uye vanhu vose, vanobhadhara kuongorora genotypic.
Kuongorora kwePhenotype kunogona kusinganzwisisiki nevamwe bhizimisi. Nguva dzose chengeta neinishuwarenzi yako muperekedzi kuti uone kana iyi miedzo inosanganiswa muzvikomborero zvako.
Dzidza zvakawanda nezvekuti HIV genotyping uye phenotyping zvinoshanda sei .
Sources:
World Health Organization (WHO). "Utachiona hweHIV Hwokurwisana Chikamu Sheet." Geneva, Switzerland; April 11, 2011.
Taniguchi, T .; Nuritdinova, D .; Grubb, J .; et al. "Kutapukiswa kwezvirwere zvinopesana nehutachiwana hwehutachiona hweHIV hunoramba hwakapararira uye hunoita kuti zvirwere zve virologic zvisati zvaitika pasinei neve genotype-inotungamirirwa nehutachiona hwehutachiona." AIDS Kuongorora Vanhu Retroviruses. March 5, 2012; 28 (3): 259-264.
Kuhn, L .; Kuramba, G .; Technau, K; et al. "Kurapa zvinodhaka pakati pevachangobva kuongororwa vane HIV vane utachiona munguva yehutachiona hwehutachiona hweprotroviral prophylaxis." AIDS. April 30, 2014; 8: 1673-1678.
National Institutes of Health (NIH). "Nhungamiro Yekushandisa Antiretroviral Agents muHIV-1-Vakabatwa Vakuru Nevana Vari Kuyaruka." Bethesda, Maryland; Gunyana 11, 2013.