Marudzi e insulini akashandiswa kutsigira mamiriro ekurapa
Kana zvasvika pakutora insulini , pane maitiro mazhinji ehomoni inoparadzaniswa nehanho ravanoita. Izvi, zvakare, zvinotarisa kuti uye fomu imwe neimwe inoshandiswa sei uye sei. Munhu wose ane chirwere cheshuga chechirwere chechirwere , uye vamwe vane chirwere cheshuga chechipiri , vanoda kutora insulini kuti vabudirire kugadzira glucose kubva pane zvokudya.
Nechirwere cheshuga 1, izvi ndezvokuti pancreas haigoni kuita hormone.
Nechirwere chechipiri chirwere cheshuga, pancreas inokwanisa kuita insulin, asi muviri hautaurizve sezvaunofanirwa uye unoda kuwedzerwa insulini kuti ubhadhara.
Basa reSvondo-Yakareba uye Rinopfupika Kuita insulin
Insulin inopiwa murefu maitiro maitiro kuitira kuti zvive nechokwadi chekugadziriswa kwekuchengetedza kwehuwandu hwe insulin, asi maitiro mashomanana ari kuita zvinotadzisa kupedzisira kusinganisa kwekasiga muropa.
- Isu tinotaura nezvehuwandu hwemaitiro anenge saral insalin (basal rinoreva "maruva") sezvo inoshanda kumashure kuti kuchengetedza shuga yakagadzikana.
- Mifananidzo shoma-maitiro inonzi " bolus insulin" ("bolus" inoreva "chirwere chimwe chete") sezvo ichi chinoreva kutorwa zvakananga panguva dzekudya kuti kuchengeta mashiga eropa mushure mekutonga.
Nzira yekuti Bolus Insulin Inoshanda Sei
Bolus insulini inoreva chiyero chinowedzera che insulini iyo pancreas inowanzobereka mukupindura shuga (glucose) inotorwa kuburikidza nekudya. Iko yehuwandu hwekugadzira hunoenderana nekukura uye rudzi rwekudya kunobatanidzwa.
Muvanhu vane chirwere cheshuga chirwere cheshuga, pancreas haichagoni kuita insulini semasero e beta anobudisa hormone yakavhara zvikuru. Nemhaka yeizvi, bolus insulin ichashandiswa, kana ichidiwa, kubhadhara kurasikirwa uku.
Kuchengetedza kuenderera mberi kwekugadzirisa kwehuga hwehuga, vanhu vazhinji vanowanzotevera bheal-bolus regimen umo tsvimbo shomanana dzomumwe nomumwe dzinotorwa zuva rese nekuda kwekupedzisira uye nguva yekugadzirisa nguva yekudya.
Bolus insulini inowanikwa nejisi, asi insalin inogona kununurwa kana nejisi kana kuti inopfuurira, maawa makumi maviri nemasere ekuputi .
Mhando dzeBolus Insulin
Kune marudzi maviri e-bolus insulin: kukurumidza-kuita (inozivikanwawo sekukurumidza-kuita) uye maitiro mashoma ekuita insulin (anozivikanwawo sekugara insulin nguva dzose). Misiyano mina huru pakati pemhando idzi dze insulin ndeyokuti:
- Vanokurumidza kusvika sei muropa
- Apo vanotanga kuderedza shuga yeropa (kutanga kutora)
- Pavanotanga kushanda zvakaoma kwazvo (peak action)
- Inguva yakadini iyo inotora (nguva)
Kukurumidza-kuita bhutu insulin inogona kutanga kuderedza shuga yako yeropa mukati maminitsi mashanu kusvika ku15. Maitiro mashoma-kuita insulin, zvakasiyana, ane kutanga kwemaminitsi makumi matatu. Zvose zviri zviviri zvine uremu hwemaawa mashanu.
(Muna 2015, chimiro chakakonzerwa nekukurumidza-kuita insulin, chinonzi Afrezza, chakava kuwanikwa muU.S. Kunyange zvakadaro, mutengi, uye mutarisiri kusava nehanya vakatungamirira mugadziri kurega kushambadzira nguva pfupi mushure mekubudiswa kwechigadzirwa.)
Mitambo yeRaidid-Acting Bolus Insulins
Ikozvino pane zvitatu zvakakurumidza-kuita insulin inobvumirwa neU.S. Food and Drug Administration (FDA):
- Novolog (insulin aspart injection)
- Kutarisa chiito: maminitsi mashanu kusvika ku15
- Peak action: imwe kusvika maawa matatu
- Nguva yakatarwa: maawa matatu kusvika mashanu
- Apidra (insulin namglulisine injection)
- Onset action; maminitsi mashanu kusvika ku15
- Peak action: 30 kusvika 90 maminitsi
- Nguva yakatarwa: maawa matatu kusvika mashanu
- Humalog (insulin lispro injection)
- Onset action; maminitsi mashanu kusvika ku15
- Peak action: 30 kusvika 90 maminitsi
- Nguva yakatarwa: maawa matatu kusvika mashanu
Mhando dzePfupi-Acting Bolus Insulin
Ikozvino pane maitiro maviri maitiro mashoma ekuita insulin anogamuchirwa neCDA. Zvose izvi zvinorondedzerwa se "nguva dzose" insulini inoshandisa izwi (R).
- Humulin (R)
- Kutarisana nekuita: maminitsi gumi nemashanu
- Peak action: maawa maviri kusvika mana
- Nguva yakatarwa: maawa mashanu kusvika masere
- Novolin (R)
- Kutarisana nekuita: maminitsi gumi nemashanu
- Peak action: maawa maviri kusvika mana
- Nguva yakatarwa: maawa mashanu kusvika masere
> Kwakabva:
> American Diabetes Association. "7. Nzira dzeGlycemic Treatment." Chirwere cheshuga . January 2016; 39 (Suppl 1): S52-S59.