Zvokudya zveG Gluten Zvingabatsira Kubata Matambudziko aLou Gehrig Here?
Vamwe vanhu vane utano hwehutano hunotyisa hwemauroto amyotrophic lateral sclerosis - inozivikanwa seA ALS, kana chirwere chaLou Gehrig - ine huwandu hwakawanda hwehutachiona hunokwidza huchifamba mumitumbi yavo, kumutsa mubvunzo wekuti kudya kweguten kunogona kubatsira mukurapa chirwere, chidzidzo chinoratidza.
Zvisinei, vatsvakurudzi vakaita sarudzo vakanyevera kuti zvaakawana ndezvokutanga uye zvinofanira kusimbiswa nekutsvakurudza mberi pamberi pechiremba vachifunga kuti vanorapa varwere vavo vane ALS nezvokudya zvisina kudya.
Masayendisiti, anobva kuTel Aviv Medical Centre muIsrael, iye zvino ari kuita kuongorora kuongororwa kuongororwa nemigumisiro yekuenda kune-gluten-vasingabhadharwi nevarwere vane ALS vane zvirwere zvekurwisana ne gluten.
"Nyaya inobva kuongororo ino inoratidza kuti, pane dzimwe nguva, ALS syndrome inogona kubatanidzwa ne autoimmunity uye gluten senzwi," vakatsvakurudza vakanyora mubhuku, rakabudiswa muna April 2015 mubhuku rezvokurapa JAMA Neurology . "Kunyange zvazvo mashoko acho ari ekutanga uye achida kudzokorora, kushushikana kweguten kunogona kurapwa; saka, iyi dambudziko rekuongororwa harifaniri kuregererwa."
Kurapa kweAlS Ingave Yakakosha
ALS chirwere chinoramba chichiwedzera uye chinowanzoguma - kazhinji mukati memakore mashomanana ekuongororwa - mukuora simba uye kufa. Vanenge 5 600 vanhu vanoongororwa vane ALS gore rega rega muU.S., uye mamiriro acho akazara pakati pemakore makumi mana nemakumi matanhatu. Chirwere ichi chinokonzera kuora kwechikamu chepelinha chinokonzerwa nekufamba.
Iwe unogona kunge uchiziva nezvemamiriro ezvinhu kubva mukushambadzira kukuru kwakagadzirwa muzhizha ra2014 neA ALS Ice Bucket Challenge, iyo yakasvibiswa nehutano hwehupfumi uye yakakura kudarika $ 100 mamiriyoni ekutsigirwa kweA ALS nekutsvakurudza.
Kuwana mushonga weAAL unobatsira vamwe vanhu kuti vashandise - kunyange kana kurapwa ikoko kuchibudirira chete mudiki kadiki yevaya vane ALS - ingava yakakosha.
Parizvino, pane chirwere chimwe chete chinogamuchirwa neAAL, uye kurapa kunowanzoisa pfungwa pakuenderera mberi kwekuwedzera kwezviratidzo apo uchibatsira varwere kubata zviratidzo zvavo zviri nani.
Iyi haisi nguva yokutanga kuti vanachiremba vakaratidza kuwirirana pakati pezvirwere zvechiliac uye / kana kuti kwete-celiac gluten senzwive uye ALS. Zvinyorwa zviviri zvakabudiswa nenyaya dzinotsanangura varwere pakutanga vakaongororwa vane ALS, asi avo vakazongororwa vakawana panzvimbo yezvirwere zvechiliac uye zviratidzo zvavo zvakavandudzwa kana vaenda vasina kugwinya.
Zvisinei, chidzidzo chikuru chakabudiswa muna 2014 chakakundikana kuwana chero kuwirirana pakati pezvirwere zvechiliac, kunyanya, uye zvakazoonekwa kuti ALS.
Tel Aviv Yokudzidza Yakarisa Kuipa Kwemaitiro Anormalmal
Kunyanya kutsvakurudzwa kwevaIsrael kubva kune vatsvakurudzi veIsrael vaisanganisira varwere 150 veA ALS vakaonekwa pamwe chete pakati paJuly 2010 naDecember 2012, uye pamwe nenyaya 115 dzine utano hwehutano hwakaiswa pakuenzanisa.
Vatsvakurudzi vakaita ropa rekuongorora zvirwere zve gluten zvinosangana nechirwere chechiliac uye vakaona kuti hapana munhu weboka rimwe nerimwe aiva nemasikirwo iwayo, zvinoreva kuti ivo vanenge vasina chirwere cheliacac.
Vatsvakurudzi vakatsvaga rudzi rwakasiyana rwehutachiona hunonzi "IgA-Transglutaminase-6" (IgA-TG6), risingarevi muchirwere ichi.
Zvisinei, IgA-TG6 inobatanidzwa mune zvimwe zvidzidzo kusvika kune gluten ataxia , iyo inogadziriswa neurological condition umo muviri unopindura kuguten kushandiswa nekurwisa neuron yayo. Gluten ataxia inogona kutungamirira kukuremara, kuwedzera kwekuremara mumatambudziko akaoma.
Chidzidzo chacho chakawana kuti varwere vane ALS 23 - kana 15.3% - vaiva nepamusoro yeAgA-TG6 zvirwere zvinokonzera gluten, zvichienzaniswa ne 4.3% chete zvekutonga. Mukuwedzera, inenge 59% yevarwere ve ALS vane zvirwere zvejuten zvinotakurawo imwe yejeni yezvirwere izvi .
Vaya varwere ve ALS vaiva neAgA-TG6 zvirwere zvinokonzerwa nemaropa zvinokwira mumaropa avo zvakaratidza izvo boka racho rainzi "mifananidzo yekare yaAls," yakafanana nevarwere ve ALS vasina zvirwere zveGluten - mune mamwe mazwi, vanachiremba vakanga vasingagoni kutaurira mapoka maviri .
Saka Izvi Zvose Zvinorevei?
Izvo hazvisi pachena zvakare. Sezvandakanyora pamusoro apa, vatsvakurudzo vanobatanidzwa mukudzidza uku vakanyatsomunyevera nekusaverenga zvakanyanya mukati maro, kunyange vari kuedza kana kuve kusina-gluten kunogona kubatsira kurapa ALS, kunyanya muchikamu chevanhu vane izvi IgA-TG6 zvirwere zvinokonzera.
Kana zviwanikwa zvavo zvichitsanangurwa, zvimwe danho rinotevera raizove kuitisa chirongwa chekliniki kuti uone kana kudya kwe-gluten kusingabatsiri varwere vane ALS uye IgA-TG6. Zvirongwa zvekudzidza kwakadaro zviri kuitika. "Kuongorora kwedu kunoratidza kuti ALS syndrome inobatana nekunzwisisa kwe gluten inogona kuitika muboka revarwere uye kuti TG6 IgA autoantibodies inogona kuva chiratidzo chekuziva varwere vane utachiona," vakatsvakurudza vakapedzisa.
Sources:
Brown KJ et al. Nyaya yakachena yezvipembenene zvinoratidza kuti amyotrophic lateral sclerosis inokonzerwa nechirwere chechiliac. American Journal of Neuroradiology . 2010 May; 31 (5): 880-1.
Gadhiti A et al. Transglutaminase 6 Antibodies muSerum yevarwere Ne Amyotrophic Lateral Sclerosis. JAMA Neurology . Yakabudiswa paIndaneti April 13, 2015.
Ludvigsson JF et al. Hapana kuwirirana pakati pezvirwere zvechiopia-zvakavimbiswa neecliac uye zvinotevera zvinonzi amyotrophic lateral sclerosis - vanhu-based cohort study. European Journal of Neurology . 2014 Jul; 21 (7): 976-82.