Nhano Yokutanga Mukuona
Kuedza kwechirwere chechiliac inowanzotanga nekuongorora ropa. Iyi miedzo inotarisa kuti muviri wako unoita sei kune gluten , puroteni inowanikwa mugorosi, nebhari, uye rye zvinokonzera chirwere ichi.
Kuyera ropa hakuna kukwana. Kana ropa rako risina kumira rakashata, zvinoreva kuti hauna mikana yekuve nechirwere chechiliac, asi kuchine mukana muduku wekuti iwe unayo.
Kana ropa rako riripo rakanaka, zvinoreva kuti iwe unowanzova nechirwere checliac, kunyange iwe uchiri (kazhinji) unoda kuendeswa kurapwa kunozivikanwa se endoscopy kuti uone kuongororwa.
Munguva iyoyo endoscopy, chiremba wako achaisa huputi mukati mako mudumbu uye kusvika kumusoro kwemukati mako mudumbu, uye achazochera zviduku zviduku kubva pamucheka wako wepamukati kuti uongorore pasi pe microscope. Kana izvi zvinyorwa zvisikwa zvinoratidza kuipa kwechirwere, chimiro chemukati chirwere chinowanikwa muhosha yechiliac, saka iwe une mamiriro acho.
Hungu, inotora nguva yakareba, uye zvose zvinotanga nedzimwe ropa dzinoongorora.
Ipi Ropa Rinoedzwa Rinoitwa
Chirwere chechiliac chirwere chekutsvaga chinotarisa zvirwere zvinoratidza maitiro ezvirwere zvemuviri wako kune gluten mukudya kwako-ndicho chikonzero iwe unofanirwa kunge uchidya gluten paunoongororwa chirwere chechiliac. Kana iwe usisiri kudya guten panguva yekuedzwa, kuongororwa kweropa kuchave kusina kunaka kunyange iwe unenge uine chirwere checliac.
Pane zviyero zvitatu zvekuongorora ropa zvaungadai wakaita apo uri kuedzwa kwechirwere ichi:
- AGA (antigliadin antibodies) -AgA
- AGA-IgG
- tTG (anti-tissue transglutaminase) -AgA
- EMA (anti-endomysial antibodies) -IgA
- Total serum IgA
Hungu, ivo vose vanoita sendifu yeshoko. Asi mimwe miedzo iyi inotarisa zvikamu zvemuviri wako wechirwere chemuviri kuti uone kana muviri wako uri kuita seprotheni ye gluten mune zvokudya zvauri kudya.
Pamuedzo uyu wose, kuongororwa kweEA-IgA yeropa kunofungidzirwa kuti ndiyo yakanyatsokodzera kuongororwa ropa kune chirwere ichi, chinoreva kuti kana iwe uine mhinduro yakanaka pane EMA-IgA, iwe unogona kunge une chirwere chechiliac. Zvisinei, EMA-IgA inogonawo kukanganisa vamwe vanhu vane chirwere chechiliac, kunyanya kana vakangotanga kukura mamiriro acho.
Kana iwe uchifarira zvinhu zvekodzero: EMA inomirira antiendomysial antibodies, iyo inopesana nemasikirwo anobudiswa nemuviri unorwisa muviri wemuviri. IgA, kana kuti immunoglobulin A, inowanzoshandiswa nehutachiona hunogadzirwa nemuviri wako. Basa rayo nderokubatsira muviri kuziva nekurwisa vanopinda kune dzimwe nyika sevakasviki vemo, zvipembenene, uye mavairasi.
Zvimwe Zvingaita Zvimwe Zvidzidzo zveCeliac
Kuongorora ropa kunozivikanwa seAAA-IgA, AGA-IgG, uye tTG-IgA zvakare kunogona kuratidza muviri wako uri kuita zvinoenderana neprotheni ye gluten ... uye inogona kutotadza kuziva vamwe vanhu vane chirwere chechiliac iyo inowanzova yakarurama EMA-IgA test misses.
Kunyange zvakadaro, miedzo iyi inogonawo kubereka dzimwe pfungwa dzenhema, iyo ndiko kuedzwa kunodzoka nemugumisiro wakanaka, asi munhu haana chaizvoizvo ane chirwere ichi. Ndosaka dzimwe nyanzvi dzechirwere dzechiliac dzinokurudzira kuita zvose zvese kuedza pamwe-unogona kuwana mufananidzo wakazara nenzira iyo.
Mune zvimwe zviitiko, vanhu vane chirwere cheshuga chirwere chetachiona , chirwere chetachiona , uye autoimmune chirwere chechiropa chinokurudzira pane chimwe chezviedzo, chirongwa cheTTG-IgA, zvichienderana nemamwe mamiriro avo. TTG inomirira tissue transglutaminase, enzyme inowanika mumatumbo.
A positive tTG-IgA kuongororwa kweropa kunoratidza kuti muviri unoita zvirongwa zvezvirwere zvayo, izvo zvinogona kuitika mukupindura kuguten kuwedzerwa. Zvisinei, hazvirevi nguva dzose kuti une chirwere chechiliac, kunyanya kana iwe uine imwe yemamwe mamiriro akanyorwa. Saka kana uine chimwe chezviitiko izvi, chiremba wako angangodaro anotarisa zvakanyanya pamigumisiro yeimwe steroliac yezvirwere zveropa.
Pakupedzisira, jekesheni yeiyoac test blood inowanzobatanidza kuongorora kutarisa kuti yakawanda yeAn antibody, immunoglobulin A, muviri wako unoita. Izvi zvakakosha nokuti vanhu vari pasi pechirwere ichi (inozivikanwa seIgA) vanogona kuva nemigumisiro yakaipa pane chirwere chechiliac chirwere cheropa, kunyange kana ivo vane mamiriro ezvinhu.
Uye, izvi zvinotonyanya kukosha nokuti vanhu vane chirwere chechiliac vanotambura nemamiriro ezvinhu aya, anozivikanwa seAgA inoshaya , inenge 10 kusvika ku15 kazhinji pane vanhu vakawanda.
Vamwe vanachiremba vanoshandisa imwe yezviedzo izvi- antigliadin antibodies-IgG, kana kuti AGA-IgG -kuvanhu vechiratidzo chekusagadzikana kwekunyepedzeka kweguteniti . Zvisinei, vatsvakurudzi vakaratidza kuti haisi yakanyatsokodzera kune chinangwa ichocho, uye sekunozvino, masayendisiti haana kumbogadzira kuedza kwakarurama kwekunzwa kwekutya kwe gluten.
Celiac Gene Testing
Vamwe vanachiremba vanokurudzirawo kuedza mamwe mazita ejeni anowedzera dambudziko rako rekushaya chirwere ichi. Kana iwe watototanga kudya kwe-gluten , izvi zvingangova kuongororwa chete chiremba wako anokurudzira kumhanya (miedzo yandinotsanangura pamusoro apa haina kururama kunze kwekuti uri kudya gluten).
Izvozvo zvinokonzerwa nemamiriyoni ejeni hazvirevi kuti maitiro anokonzera gemen; panzvimbo pacho, vanotarisa mazita maviri emagetsi, HLA-DQ2 uye HLA-DQ8 , iyo yakabatanidzwa nechirwere ichi. Majini ako haashanduki, kunyange iwe uri kudya gluten-isina.
Iye zvino, chimiro chechiliac chimiro chakanaka hachirevi kuti une chirwere chechiliac-zvinongoreva kuti une "maitiro" maitiro kuitira kuti uve nemamiriro ezvinhu. Kana imwe yeropa rako risiri rakanaka asi iwe geni rinosangana zvakanaka, iwe nachiremba wako ungasarudza kuti iwe unofanira kurega kudya gluten kwenguva yekuedzwa kuti uone kana zviratidzo zvezvirwere zvechiliac zviri pachena.
Sources:
Serologic uye Genetic Testing. Celiac Disease Center paColumbia University Medical Center.
Yunivhesiti yeMadganist Center yeCeliac Research. Dambudziko reCeliac: Inowanzobvunzwa mibvunzo fact sheet