Chimwe chimiro chepfungwa chinokonzera chivimbiso chekurapa zvinhu zve autism
Anotsvakurudza Anoti Iye "Akawana Pathology yeAustism"
Dr. Manuel Casanova anotsigira chigaro chakagadzwa paYunivhesiti yeKentucky. Akanyora mazamu akawanda emabhuku, uye anogamuchira mari kubva kuNational Institutes of Health. Dr. Casanova ari kuita tsvakurudzo pamusoro pehutano hwe autistic - uye, maererano naye: "Ndinofunga kuti tawana hutachiona hwe autism.
... Rinotsanangura zvakanyanya, zvose zvinonzwisisika. "
Haisi kungoti Dr. Casanova anotenda kuti akawana hutachiona hwe autism, asi ari kushandawo mukurapa iyo inogona kuva nekwanisi kuderedza zviratidzo zveviristic zve hypersensitivity pasina kukanganisa kusanganisa uye unyanzvi hunoita kuti vanhu vaidistic vaite zvakanyanya.
Minicolumns mu Autistic Brain: Mashoko Akanaka uye Nhau Dzakaipa
Chikamu chekunze cheropi chinonzi neocortex. Mukati reNeocortex mune mapoka emasero anonzi minicolumns. Iyi minicolumns ndiyo inonyanya kudarika masero anokwanisa kugadzirisa mashoko. Kazhinji, minicolumns inosanganisira masero mashoma, anonzi neurons, anobvumira kukurukurirana kwete mukati memunhu mumwechete asiwo pakati pezvikamu zvakasiyana zveuropi.
Minicolumns muvanhu vane autism maduku uye akawanda kupfuura zvese. Mukuwedzera, neurons mukati mega roga roga rinoderedzwa muhukuru.
Izvi zvinogona kunge zviri zviviri zvakanaka uye zvakaipa, inoti Casanova: "Sezvo kubudirira kwehutano pakati pe-neuroni kushanda kwemasero esero, kuvapo kweionon zviduku muuropi hwevatachiona ve autistic kune zvakakosha munzira iyo dzakasiyana zvikamu zveuropi kuwirirana nemumwe nemumwe. Kuita zvinhu zvinoda nguva refu (semuenzaniso, mutauro) zvingave zvisina kukanganisa apo izvo zvinoenderana nehupfupi kuwirirana (semuenzaniso, mathematical manipulations) zvinogona kuchengetedzwa kana kusimbiswa. "
Mune mamwe mazwi, vanhu vane autism vakanaka zvikuru pane chero chipi zvacho chinogona kushandiswa mune imwe nzvimbo yeuropi - zvakadai semasvomhu uye kusarura kunoonekwa. Ivo, zvisinei, zvakashata pane chero chinhu chinoda kubatanidza pakati pezvikamu zvakasiyana-siyana zveuropi - zvakadai sehutano hwevanhu , mutauro, uye kusarura kusarura.
Kutsigira Zvakaipa Pakati PeMinicolumns Kunogona Kukonzera Matambudziko Akangwara
Maererano neCasanova, imwe yechirongwa chemashoko emamwe masero emamwe mashomanana anonzi "stimuli haasisiri mune zvinyorwa zveminicolumns asi zvinowedzera kupfuurira kune zvinyorwa zvinyorwa zvishoma uye zvinopa simba rekusimudzira. Izvi zvinogona kutsanangura hutachiona hwevamwe varwere vese kugumburwa. "
Casanova inofanidza izvi nemvura iri mumvura. "Muchengetedzwa inoshandiswa nenzira inofanana neketeni." Pakushanda zvakajeka uye zvakakwana kuvhara bhati bhajiro remvura rinodzivirira mvura kuti irege kuerera pasi. " Vanhu vane autism vane mvura yakadzika yemaketeni.
Kuwedzera Kuisa Mukana Kunogona Kudzidza Zvidzidzo Zvisinganzwisisiki uye Kutambudza Pasina Kukanganisa Kubata
Dr. Casanova anotenda kuti zvinokwanisika kuwedzera "kusungirirwa" kwakapoteredza minicolumns, zvichiita kuti kuderedza kunetseka kunowedzera uye kukanganisa kwekugumburwa.
Runako hwepfungwa yake ndeyekuti izvi zvinokanganisa zvinogona kutariswa zvisingabatanidzi kukwanisa kwevanhu vane autism kufunga, kuona nekusika kunze kwebhokisi.
Hezvino iyo inoshanda sei: Maererano neCasanova, "nzvimbo huru yezvi [minicolumn] seli uye maitiro ndeokuti dzinomira pamakiromita makumi mapfumbamwe kusvika kumativi e-cortex." Ndiwo chete masero anoita izvozvo. " Casanova inofunga kuti kutenderera magnetic stimulation (TMS) inogona "kuisa magnetic field mu cortex," nokudaro kusimbisa kuvharidzirwa kunopoteredza minicolumns. Iyi kurapwa yaizo (maererano nekutsvakurudza ikozvino) inenge isina simba.
Zvinonyanya kukosha, hazvizove nemigumisiro yechiratidzo chekuchinja unhu kana pfungwa dzekufunga dzemunhu anenge achirapwa.
Ko TMS ingakwanisa kuva "Chiito chechokwadi here?"
Ichi chirevo hachisi chisingaoneki sezvinogona kurira. Kutaura zvazviri, TMS yakatove yakabatsira pakurapa zvirwere zvepfungwa zvakadai schizophrenia uye kuora mwoyo. Mishonga yemakiriniki iri kuenderera mberi kuburikidza neNIH kuongorora kubatsira kweTMS mukurapa mazwi emagetsi. Mukufamba kwemazana emakore, masangano akasiyana-siyana akaedza miedzo yeTMS - asi kusvikira zvino hapana kubvumirana pamusoro pemigumisiro. Kunyange zvazvo miedzo paHarvard nedzimwe nzvimbo ichiita seine chivimbiso, uye nyaya mumabhuku akadai seNewsweek akanaka, TMS inoramba ichirapa iyo isati yakagadzirira kushandiswa kwevakawanda.
References:
Inobvunzurudza foni neDr. Manuel Casanova. Svondo, 2006.
Casanova MF, Kooten IAJ van, Switala AE, Engeland H van, Heinsen H, Steinbusch HWM, Hof PR, Schmitz C. Kusagadzikana kwekortical minicolumnar in the prefrontal lobes of autistic patients. Clinical Neuroscience Research 2006; 6 (3-4), 127-133.
Casanova MF, Kooten IAJ van, Switala AE, Engeland H van, Heinsen H, Steinbusch HWM, Hof PR, Kuronga J, Stone J, Schmitz C. Zvimwe zvisingaiti mu autism. Acta Neuropathologica 2006; 112 (3), 287-303.
Casanova MF, Abnormalities Of Cortical Circuitry In The Brains Of Autistic Individuals. Yakapiwa kuWall Wales Autism Resource (AWARES) Musangano Wenyika Yose, 2006.
Chae, JH, Nahas, Z., Wassermann, E., Li, X., Sethuraman, G., Gilbert, D., et al. (2004). Mufambisi wengororo yekudzidzira yekudzokorora kudzokorora magnetic stimulation (rTMS) mu Tourette's syndrome. Kuziva uye Kuzvibata Neurology, 17 (2), 109-117.
Mantovani, A., Lisanby, SH, Pieraccini, F., Ulivelli, M., Castrogiovanni, P., & Rossi, S. (2006). Kudzokorora kugadzirisa magnetic stimulation (rTMS) mukurapa kwekusagadzikana-kusagadzirisa chirwere (OCD) uye Tourette's syndrome (TS). International Journal yeNeuropsychopharmacology, 9 (1), 95-100.