Zvimwe zviratidzo zvePypyramidal (EPS) zviratidzo zvinowedzera mumuviri wehutano hwedu hwemuviri hunokonzera kusununguka kana kusadzora kutenderera. Zviratidzo izvi zvinogona kunge zviri munzvimbo dzakasiyana-siyana mumuviri, kusanganisira trunk, maoko, makumbo, tsoka, mutsipa, muromo, uye maziso.
Paunotarisa kune mumwe munhu ane EPS, zvichienderana nokuti pane zviratidzo zvipi, unogona kuona mumwe munhu achifambisa muviri wake wepamusoro, achirova tsoka kana mwendo nguva zhinji, achinyora miromo yavo kana kuisa rurimi rwavo kumativi ose.
Iwe unogona kuona kuti vane dambudziko nekuchengetedza kugara kwakanaka kana kufamba zvakanaka.
Iko extrapyramidal motokari inonzi neural network inenge iri muuropi iyo inobatanidzwa mukubatanidza nekudzivirira kwekufamba kusanganisira kutanga nekumira kwekutama uye nekuraira kuti yakasimba uye inokurumidza kufamba kupi. Zvimwe zviratidzo zvePpypyramidal, naizvozvo, zviratidzo zvinoratidza kuti sekushayikwa kwekufambidzana nekudzora kufamba.
Chii Chinokonzera EPS?
EPS ndiyo imwe yemigumisiro yakawanda yemigumisiro yemishonga inorwisa antipsychotic . Antipsychotic mishonga- sezita rinonzwika- kubata (kana, "anti") zvinetso zvepfungwa. Iyi mishonga inowanzoshandiswa kurapa vanhu vane schizophrenia vari kuona maitiro ekunyengedza uye kunyengera . Vakatarirwawo "off-label" (kwete yekushandiswa kwakagamuchirwa neU.S. Food and Drug Administration) kune vanhu vane Alzheimer uye mamwe marudzi ehutano hwemagariro evanhu vane miitiro yakaoma yakaoma yakadai sechisimba uye kushungurudzika kwakanyanya.
EPS inogona kutanga nekukurumidza pashure pokunge mishonga inorwisa antipsychotic yakatangwa kana inogona kukura mushure mekunge mishonga yatorwa kwemwedzi yakawanda.
Zvimwe zviratidzo zvePypyramidal zvinowanzova zvakajairika nemishonga yakare inorapwa antipsychotics yakadai sechlorpromazine (Thorazine), thioridazine (Mellaril) uye haloperidol (Haldol) .
Zviratidzo izvi hazviwanzozivikanwi kune vanhu vanotora mutsva anypical antipsychotics setitiapine (Seroquel), risperidone (Risperdal) uye olanzapine (Zyprexa) .
Symptoms of Extrapyramidal Side Effects
- Kushamwaridzana kushamwaridzana
- Kuvhunduka uye kugadzikana
- Mutumbi kusagadzikana
- Muscle contractions
- Mask-like face
- Kushamwaridzana kunokonzerwa kweziso rinonzi oculogyric dambudziko
- Drooling
- Shuffling gait
- Kuwedzera kwenhamba yemwoyo
- Delirium
Kuongorora kweAdpyramidal Symptoms
Kana mumwe munhu ari kugamuchira mishonga inorwisa antisyytictic, inofanirwa kugara ichiongororwa yeEPS. Vamwe vanachiremba vanoongororwa neEPS kubva mushumo unobva kumunhu kana nhengo yemhuri yake, uyewo maonero avo pachake. Vamwe vanovimba nesarudzo dzakarongwa dzakarongeka dzakagadzirirwa kugadzirisa kuongorora EPS. Mienzaniso miviri yezviyero izvi ndeyeAbnormal Involuntary Movement Scale (AIMS), iyo Extrapyramidal Symptom Rating Scale (ESRS) uye Dyskinesia Identification System: Condensed User Scale (DISCUS).
Kurapa kwe Extrapyramidal Symptoms
Kuziva nekubata EPS nokukurumidza zvakakosha kunokosha zvikuru. EPS nokuti izvi zvinogadzirisa zvinogona kuva zvechigarire kune vamwe vanhu.
Chokutanga chekurapa extrapyramidal zviratidzo izvo zvinokonzerwa nemishonga inorwisa antipychotic inosanganisira kuderedza nekuregera mishonga uye zvino kufunga nezveimwe mushonga mushonga.
Chiremba wako anogonawo kusarudza kuongorora njodzi uye kubatsirwe kwemishonga inopesana nehutachiona uye kuronga mishonga yakasiyana-siyana kuedza kurwisana neEPS kana yainzwa kuti chirwere chepachirwere chekare chinoda chaizvo.
Kushandisa Antipsychotic Mishonga Yokubata Vanhu neDementia
Nemhaka yezvinogona kukonzerwa nemigumisiro yakakomba, mishonga inorwisa antipychotic haigamuchirwi sekurapa kwezvinetso zvakaoma kune vakwegura vakuru vane dhementi. Zvisiri-zvinodhaka zvinoshandiswa zvinofanira kuva nzira yekutanga mukugadzirisa maitiro aya .
Zvisinei, kana munhu ane dementia ari kutambudzika zvechokwadi nokuti ari kunyengedzwa kana kuve nekufungidzira, kana kuti ari kuzviisa iye pachake kana kuti vamwe vari pangozi nechisimba chisina kudzora chisimba, kurapwa ne antipsychotic kunogona kunge kwakakodzera.
Kuongororwa kweEPS nezvimwewo migumisiro zvakakosha zvikuru-kunyanya kune vanhu vane Lewy body dementia vane ngozi yakawanda yekuita mishonga iyi.
> Sources:
> The American Geriatrics Society. Nhungamiro Yekutungamira kwePsychotic Disorders uye Neuropsychiatric Zviratidzo zveDhementia muVakuru Vakuru. April 2011.
> Schizophrenia Research . Svondo 15, 2005. Bhuku 77, Zvinyorwa 2-3, Mapeji 119-128. Abnormal Involuntary Movement Scale (AIMS) uye Extrapyramidal Symptom Rating Scale (ESRS): Kuenzanisa Kuyerana Mukuongorora Tardive Dyskinesia.
> University of Central Florida. Neural Pathways.
-Edited naEsther Heerema, MSW