Kuyera Ropa Rinoyera Matwere Chiito muRheumatoid Arthritis
Kune maitiro mashomanana eropa iro vanachiremba vanoronga kuti vaongorore kuchema uye kuti vabatsire kuongorora arthritis. Kuongorora kweropa kunowanzoitwa nevarwere vanofungidzirwa kuti vane rheumatoid arthritis , kana kutarisa kubudirira kwehutano, vanosanganisira chirongwa che erythrocyte sedimentation , CRP , rheumatoid factor , uye anti-CCP . Asi, pane "mwana mutsva" pachivako, kutaura-mumiriri-kutaura, kunonzi Vectra DA.
Vectra DA, yakagadzirwa neCrescendo Bioscience, inotaridzika yakawanda yeropa yekuongorora ropa rheumatoid arthritis chirwere mune varwere vanobatwa neDMARDs (zvirwere-kuchinja anti-rheumatic drugs) uye biologic zvinodhaka . Vectra DHA inounganidza boka re 12 mapuroteni anokosha akabatanidzwa ne rheumatoid arthritis mumuedzo mumwechete unobudisa chinangwa, chiyero chepamusoro chine chokuita nemishonga. Nhamba yacho, 0-100 (pasi pfupi inoratidza zvirwere zvishoma zvechirwere), inobatsira vanachiremba nevarwere kuita sarudzo mukurapa sezvavanopfuurira mberi.
Vectra DA yakatanga kuziviswa pakupera kwegore ra2012. Kubva panguva iyo, maererano neCrescendo Bioscience, rheumatologists vakashandisa ruzivo urwo icho chingawanisa kupa kuongorora zvirwere zvevanhu mune rheumatoid arthritis. Vectra DA inowanikwa mune dzose makumi mashanu, uye muedzo unoitwa paCrescendo Bioscience's Clinical Laboratory Improvement Amendments (CLIA).
Mushure mokunge sampu yeropa inogamuchirwa uye yakaedzwa, zvigumisiro zvinoratidzwa mukati memakore manomwe kusvika ku10. Vanachiremba vanogona kugamuchira mhinduro mune dzimwe nzira dzakasiyana-siyana: mail mail, fax, kana pa web portal Vectra View.
Tarisa newaini yako yega yega inshurensi kuti uve nechokwadi chokuti Vectra DA inoputirwa ne inshuwarisi yako. Medicare inogadzirisa zvakakwana Vectra DA isina chekubhadhara kana kubviswa.
Crescendo Bioscience inoda kuvimbisa kuti mari haisati iri chipingamupinyi kune chero munhu ane rheumatoid arthritis uyo anofanira kunge akaedzwa. Iwe unogona kudana 1-877-RHEUMDX (1-877-743-8639) kuti udzidze nezve rubatsiro rwemari.
Vane 12 Biomarkers muVectra DA
A biomarker is molecule mumuviri inogona kuenzaniswa zvakaenzana uye kuongororwa. Inoshandiswa kutsvaga chiitiko chinowanzoitwa kana chirwere chisina kujairika chirwere, kana kubudirira kwehutano.
VCAM-1 (vascular cell adhesion molecule-1) inobatanidzwa mukubatana pakati pemasero, mitsipa yeropa, uye mishonga inobatanidza mubatanidzwa. Muzvibatanidzwa zvinokonzerwa nehurumatoid arthritis, kushamwaridzana kunogona kubatsira pakuvaka masero ekuvhiringidza.
EGF (epidermal growth factor) inokonzerwa nemasero muzvigunwe zvakabatana zvakagadziriswa nedhematoid arthritis, kukurudzira sero kukura nekuputika.
VEGF-A (vascular endothelial kukura muitiro A) inobudiswa muzvibatanidzi zvinopisa, zvichiita kuti ropa rive mumudziyo wakagadziriswa, mvura inogadziriswa, uye kuputika kwemapfupa.
IL-6 (interleukin 6) inotapa kuvhiringidza, kushaya maronda, uye kuputika kwepafu kunosanganisira rheumatoid arthritis.
TNF-RI (tumor necrosis factor receptor, chinyorwa 1) inogamuchira TNF-alpha, imwe imwe molecule inotungamirira kuwirirana nekuputika uye kuparadzwa.
MMP-1 (matrix metalloproteinase-1 kana collagenase-1) iine enzyme inokonzera kuurayiwa kwekatekiti muhutatoid arthritis.
MMP-3 (matrix metalloproteinase-3 kana stromelysin-1) iine enzyme inoparadza zvikamu zvehututi.
YKL-40 iprotini inobatsira kudzora mishonga yekugadzirisa uye kuparadzwa.
Leptin inonzi hormone yakavanzwa nemafuta ane mafuta, masero muzvibatanidza, uye bone. Leptin inobatsira kuvhiringidza uye inotungamirira mapofu ekugadzirisa.
Resistin inonzi hormone yakavanzwa nemasero ari pamwe chete nemapfupa anopa kuvhiringidza uye kutonga mapfupa ekugadzirisa.
SAA (serum amyloid) ipuroteni inoberekwa nechiropa mukupindura kwekuputika.
Serum amyloid inogona kubudiswa nemashizha akabatanidzwa pamwe chete, apo inogona kuita kuti tisii uye masero ezvirwere.
CRP (C-reactive protein) inokonzerwa nechiropa mukupindura kuputika.
Zvaunofunga Zvaunoreva
Kududzira chikamu chako kunokosha: 45 kusvika ku100 kunoratidza huwandu hwakawanda hwekuita zvirwere; 30 kusvika ku44 inoratidzira zvirwere zvine mwero; uye 1 kusvika ku29 inoratidza hutsika hwehutano hwekuita.
The Bottom Line
Vectra DA kuongorora yakakodzera kune varwere vakatoonekwa vane rheumatoid arthritis iyo, pachikumbiro chachiremba wavo, vanosarudza kuva nehuwandu hwavo hwehutano hunoongororwa. HAKASI kushandiswa kuongororwa arthritis. Inotarisa zvirwere zvekuita.
Pakazosvika 2016 EULAR (European League Against Rheumatism) musangano wegore negore, zviitiko zvakawanikwa zvakaratidzwa, kunze kwekutevera zvirwere zvekuita, Vectra DA inogona "kufanotaura kupisa uye kugadziriswa kuregererwa kune varwere vanorega kurapwa, pamwe nekurapa kurapwa kune biologic uye kwete -biologic therapies. "
> Sources:
> Vectra DA. Disease Activity Activity Test.
> Crescendo Bioscience Inozivisa kuti New Data paVectra DA Ichaendeswa kuEuropean League Against Rheumatism 17th Annual Congress. Crescendo Bioscience. June 10, 2016.