Mubvunzo: Unofanira Kutora CoQ10 neTatimins?
Chiremba wangu akandiisa pane simicastatin generic kuderedza cholesterol yangu. Ndinoita kunge ndichirirega zvakanaka, asi ndakanzwa kuti kana uri kutora mutemo wemishonga, unofanira kutorawo CoQ10 kudzivirira matambudziko emasumbu. Izvozvo ichokwadi here? Ndinofanira kutora CoQ10 here?
Mhinduro: Zvinosuruvarisa, hapana mhinduro yakananga kumubvunzo uyu.
Zvisinei, hutachiona hwechipatori chatinofanira kufambidzana hunoratidza kuti CoQ10 haibatsiri zvakawanda, kana zvakadaro, kudzivirira kana kutora matambudziko emasumbu ane statins .
Chii Chinonzi CoQ10?
CoQ10 - inozivikanwawo se ubiquinone - inonzi coenzyme inobatsira masumbu kuti aite simba ravanoda kuita basa ravo. Kunyange zvazvo dzimwe dzidzo dzakaratidza kuti statins inogona kuderedza kuwanda kweCQ10 mumashuga emasumbu, zvimwe zvidzidzo hazvina kuwana kuderera kweCQ10 mazinga nemasimoni. Saka kunyange mubvunzo wekuti statins inobata CoQ10 mazinga zvachose haisi pachena zvachose. Muzvimwe zviitiko, vazhinji vakafunga kuti zvishoma zvishoma zveCoQ10 zvinogona kuita kuti myopathy (kukuvadzwa kwemitsipa) inogona kuitika nemashizha . Saka, vamwe vanachiremba vanokurudzira CoQ10 kuwedzera pamwe neine statin therapy.
Chii Chiratidzo Pamusoro peCQ10 uye Statins?
Bhuku rezvokurapa rinosanganiswa mubvunzo weQoQ10, uye nokuda kwezvikonzero zviviri.
Kutanga, sezvakataurwa, kwete zvese zvidzidzo zvinoratidza kuti mitemo inobata maQoQ10 mazinga mumasumbu emasumbu pachake.
Uye rwechipiri, zvidzidzo neCoQ10 muvanhu vanotora maitiro zvakange zvisingakwanisi. Zvishoma zvidzidzo zvishomanana, zviduku, zvenguva pfupi zvakapedzwa, nemigumisiro yezvi zvidzidzo zvishomanana zvakange zvichinyadzisa.
Zvidzidzo zvechipatori izvo zvave zvichiitwa kusvika ikozvino zvakarongedza kukwanisa kweQoQ10 kubata marwadzo emakumbo emakumbo.
Chinangwa chezviongorori izvi ndechekuziva kuti kana kutora CoQ10 kunobvumira varwere vane marwadzo emasimoni anokonzerwa nemutemo kuti varambe vachiwana mitemo. Iyi inhau inokosha, nokuti kana zvasvika pakuderedza dambudziko remwoyo nekuda kwekushandiswa kwecholesterol, pane imwe nzvimbo isati yave yakatsiva iyo mitemo .
Izvi zvidzidzo zvakaunza migumisiro inopesana. Chirwere chekuedza kusinganzwisisiki muvanhu 32 vane chirwere chinokonzerwa nematumbo chakaita kuti, mushure memazuva makumi matatu, avo vanogamuchira CoQ10 vaine kuderedza kukuru mukurwadziwa kwemasumbu kana vachienzaniswa neavo vakagadziriswa kugamuchira vitamini E. Hupenyu hwemazuva makumi matatu hwekudzidza uku hunoonekwa dambudziko, zvisinei, nokuti zvinotora mazuva anopfuura makumi matatu eCoQ10 kubhadharira kuchinja huwandu hweCQ10 mumisungo pachavo. Uyezve, yakawanda yakafanana, miedzo yakareba kwenguva refu neCQ10 haina kuratidza huri nani mukurwadziwa kwemasumbu pane zvimiso.
Kuedza kugadzirisa nyaya yacho, meta-analysis yakagadzirwa muna 2015, kuongorora mhinduro dzinowanikwa dzisiri. Iyi kuongororwa haina kuwana ruzivo rwakakosha apo CoQ10 inoshandiswa kuporesa maitiro e-statut-induced myopathy. Zvisinei, hutano hwezvidzidzo zviripo hunoramba huri nyaya, saka migumisiro ye meta-analysis haigoni kuonekwa seyakagadzirisa.
Yakakura, yakareba-kwenguva-randomized miedzo yaizodikanwa kuwana zvechokwadi mubvunzo uyu.
Hapana chimwe cheizvi, kunyange zvakadaro, chinowanikwa kumubvunzo wako, zvinoreva kuti, munhu anofanira kutora mitemo anotorawo CoQ10 kudzivirira statin myopathy here? Chikonzero icho ndangotaura chete pamusoro pekushandisa CoQ10 kubata chirwere chinokonzerwa nemasisita ndechekuti pane zvimwe zvinyorwa zviripo zvinotarisana nemubvunzo uyu (sehuwandu hwekuti data inogona kunge iri).
Asi kana zvasvika pakushandisa CoQ10 sechiyero chekudzivirira, humwe uchapupu huripo hune zvachose unecdotal. Izvo hazvina kubudiswa maitiro anongorongedzwa anoromized anotarisa mubvunzo uyu.
CoQ10 uye Statins - The Bottom Line
Chinonyanya kukosha ndechokuti hapana uchapupu hwakanaka, huripo hunobva kuchirongwa chechipatara hunowanikwa kuratidzira kana CoQ10 ichidzivirira kana kuti inobata zvakanaka zvinokonzerwa nemarwadzo emuviri. Panguva imwecheteyo, nheyo iyo CoQ10 inogona kubatsira inoramba ichifadza, uye zvidzidzo zvakaitwa zvakanyanya zvishoma mumamiriro avo uye nguva. Uyezve, kutora CoQ10 kuwedzera (sekusvika kune munhu anoziva) hakuna chakaipa.
Saka kana iwe uchida kuedza, uye iwe unogona kuibhadhara, vanachiremba vakawanda vangataurira kwete zvakasimba kupikisa pfungwa.
Kana iwe uine kurwadziwa kwemasuru kana uri mumatemu, iwe unofanira kutaura nachiremba wako pamusoro pekuedza imwe yemishonga inonzi statin iyo inozivikanwa kuti haigoni kuunza zvinetso zvemasumbu, kureva, Lescol (fluvastatin) kana Pravachol (pravastatin). Uyewo, iva nechokwadi chokuti chiremba wako anoongorora utachiona hwehutano hwako uye huwandu hwevhitamini D yako, sezvo hypothyroidism kana kuti vitamin D yakaderera inoita sarimine myopathy zvingangoita.
> Sources:
> Banach M, Serban C, Sahebkar A, et al. Migumisiro yeKoenzyme Q10 pane Statin-induced Myopathy: Meta-kuongorora kweRandomized Controlled Trials. Mayo Clin Proc 2015; 90:24.
> Bookstaver DA, Burkhalter NA, Hatzigeorgiou C. Nzira yeCoenzyme Q10 Kuwedzera paStatin-induced Myalgias. Am J Cardiol 2012; 110: 526.
> Caso G, Kelly P, McNurlan MA, Lawson WE. Migumisiro yeKoenzyme q10 paMyopathic Zviratidzo muvarwere vanobatwa neTatimins. Am J Cardiol 2007; 99: 1409.
> Taylor BA, Whenon L, White CM, Thompson PD. Chiitiko cheRandomized Coenzyme Q10 muvarwere vane Chivimbiso Statin Myopathy. Atherosclerosis 2015; 238: 329.