Chikonzero chikuru chikonzero chiremba wako anoda kuderedza cholesterol yako kukuderedza dambudziko rako rekurwadziwa kwemoyo uye kufa nguva isati yasvika kubva kuCononary artery disease (CAD).
Uye pasinei nokuti makirasi akawanda emishonga akabvumirwa kuti aderedze LDL cholesterol (LDL ndiyo "yakaipa" maitiro echolesterol), chete mishonga yakave ichiratidzwa kakawanda kuderedza dambudziko rekurwadziwa kwemoyo nekufa kusati kwavapo kune vanhu vane moyo yepfungwa pangozi yakakwirira ndiyo mitemo .
Zvechokwadi, zvidzidzo zvepamusoro zvakatotiwo mamwe emamwe madzimai e-non-statin cholesterol mishonga anogona kuipa zvakanyanya.
Parizvino, zvinofungidzirwa kuti mitemo iri nani kudarika mamwe mishonga pakuvandudza zvigumisiro nokuti ine zvigaro zvinobatsira mukuwedzera kune cholesterol-kuderedza simba. Izvi zvinowedzera "zvinowedzera" zvinogona kubatsira kudzivirira kuputika kweatrosclerotic plaques mumaketari e coronary uye kunogona kubatsira kudzivirira acon coronary syndrome .
I-Non-Cholesterol-Inopedza Kukanganisa Kwemashoko
Izvo "zvinyorwa" zvisina-cholesterol-kuderedza migumisiro yemasitini zvinosanganisira:
- Anopesana-kupisa simba.
- Anopesana-kuvhara.
- Danda rakananga-kugadzirisa.
- Kupera kweC-reactive protein levels (CRP)
- Kuvandudzwa mune vascular function.
- Kuderedzwa kweropa remaridythmias inotyisa.
- Vamwe kuderedza (kupera) kweatrosclerotic plaques ivo pachavo.
Izvi "zvinowedzera" migumisiro yemasimoni inogona kuva yakakosha (kana kunyanya kukosha) kudarika cholesterol kuderedza mukuvandudza zvabuda.
Semuenzaniso, izvi zvisiri cholesterol migumisiro inogona kunge iri chikonzero chokuti kupa zvimiso panguva yekurwadziwa kwepfungwa kunobatsira kukurumidza kubatsirwa nemakiriniki - iyi haisi mhedzisiro waunotarisira kana chinhu bedzi statines chaiva chaiva kuderedza cholesterol. Izvi hazvisi cholesterol-kuderedzwa migumisiro inogonawo kutsanangura kuti sei mitemo inogona kugadzirisa migumisiro mune vamwe vanhu vane ngozi yakawanda avo vane cholesterol mazinga asina kunyanya kukura kutanga.
Zvechokwadi, iyo yakasiyana-siyana inobatsira mitemo yakakonzera dzimwe nyanzvi kubvunza zvose " cholesterol hypothesis " (pfungwa yokuti kuderedza cholesterol ichaderedza ngozi). Ava "vanyengeri" vanotenda kuti haisi kuderedzwa kweLDL cholesterol inoita kuti mitemo ibudirire pakuvandudza zvigumisiro, asi mamwe emigumisiro yemishonga yemutemo. Saka (vanoramba vachiratidza) zvichida kuderedza cholesterol pachayo hakusi kukosha sezvatinofunga.
The Bottom Line
Chero nzira, apo chiremba wako anokurudzira statin therapy senzira yakanakisisa yekurapa kwemishonga yako yakakwirira yeLDL cholesterol, ari kuratidza ruzivo rwake rwehumwe humwe humwe humwe uchapupu hunoratidza kuti mitemo inobatsira zvikuru.
Iwe unogona kuverenga pamusoro peimwe klesterterol-kuderedza chirwere . Uye heino nhaurwa pamusoro pokuti ungasarudza sei kana uchida kurapwa necholesterol.
> Sources:
> Liu PY, Liu YW, Lin LJ, et al. Uchapupu hweStatin Pleiotropy Muvanhu: Kusiyana kweZvirevo zveStatines Uye Ezetimibe PaRo-Associated Coiled-Coil ine Protein Kinase Activity, Endothelial Function, And Inflammation. Circulation 2009; 119: 131.
> Nissen, SE. High-Dose Statins MuAlexiconary Syndromes. Kwete Chete Lipid Level. JAMA 2004; 292: 1365.
> Stone NJ, Robinson JG, Lichtenstein AH, et al. 2013 ACC / AHA Nhungamiro Pamusoro Pokurapa Kweropa Cholesterol Kupedza Atherosclerotic Mwoyo Mungozi Muvanhu Vakawanda: Mharidzo YaAmerican College of Cardiology / American Heart Association Task Force pamusoro Pemitemo Yezvokuita. Circulation 2014; 129: S1.