Kwemakore, pane mazano ekuti vamwe vakadzi vane mazamu emvere vanogona kunge vari pangozi yekukudziridzwa kwechirwere chisingawanzoitiki. Zvisinei, uchapupu hwakanga huri pakutanga, husingarevi, uye mazwi kubva kumasangano akadai seUnited States Food and Drug Administration (FDA) uye World Health Organization (WHO) yakanga yaratidza kusava kweuchapupu.
Muna 2011, FDA inotaura mazwi anotevera pamusoro pemiti yekuisa mazamu-inobatanidza iplastiki huru cell lymphoma (ALCL):
Kunyange zvazvo ALCL isingawanzoitiki, FDA inofunga kuti vakadzi vane mazamu mazamu vanogona kuva nehuwandu hushoma asi huwandu hwekuvandudza chirwere ichi mumucheka wechipfuva pedyo nechinangwa. Kubva pane ruzivo rwakawanikwa, hazvibviri kugonesa nehuwandu hwehutano hwokuti mazamu echeche anotema ALCL.
Panguva iyoyo, FDA yakaratidzawo kuti chiitiko cheAlCL chakanga chakaderera, kunyange muchero kuisa varwere. Vakanga vasingakwanisi kuziva rudzi rwekuisa, somuenzaniso, silicone versus saline, iyo yakabatanidzwa nehuwandu hwehuwandu. Uyewo mumutauro we2011, mutauro wakabatanidza hutungamiri kune vanopa hutano, vachicherechedza kuti FDA haina kukurudzira kubvisa mazamu emvere muvarwere vasina zviratidzo kana zvimwe zvisiri izvo, asi zvakare vachitaura kuti sezvavakadzidza zvakawanda nezveAllig kuvakadzi vane mazamu emvere, izvi mazano anogona kuchinja.
Iro 2017 Yambiro Kubva kuDAA
Muna 2017, FDA yakarongedza ruzivo rwayo mune zvinyorwa nezviito zvakatorwa neW WHO, Australian Therapeutic Goods Administration, uye French National Agency yeMishonga uye Health Products Safety.
Heino chikamu chekupedzisira 2017 US FDA statement:
Kubvira muna 2011, takasimbisa kunzwisisa kwedu kwechiitiko ichi uye tinopindirana neHorld Health Organisation yekufukidzira mazamu-inosanganisira amaplastic huru cell lymphoma (BIA-ALCL) sevasingawanzo T-cell lymphoma inogona kukura pashure pezvibereko zvezamu. Nhamba chaiyo yematambudziko inoramba ichinetseka kugadzirisa nekuda kwekukanganisa kwakakosha mukurondedzera kwenyika yose nekushaikwa kwenyika yose kuwedzera kudhinda data. Panguva ino, dzakawanda deta dzinoratidza kuti BIA-ALCL inowanzoitika kakawanda mushure mekuiswa kwemafupa ezvakaberekwa nemagumbe akaiswa panzvimbo yeavo vane nzvimbo dzakashata.
Zvinorevei?
Apo nyaya dzeDFA dzichibvumirwa nezvinhu zvakadai sezviputi zvemazamu, dzimwe nguva zvinoda makambani anoita kuti aya maitiro aite zvidzidzo zvinowanikwa kuti awane mamwe mashoko pamusoro pezvinetso zvechibereko. Nenzira iyi, chirongwa chechiremba chinogona kugamuchirwa zvichienderana nouchapupu huripo, asi sezvo mamwe mashoko achibuda, FDA inovandudza mutauro wayo pamusoro pekunyevera uye njodzi.
Parizvino, FDA yakanyorwa pamusoro pezvipingamupinyi zvezviputi zvemazamu , nepamusoro-pasi kusvika, kuisa zvinetso zvakajairika kutanga, kusanganisira:
- Capsular chibvumirano
- Reoperation
- Kusimudza kubviswa (kana kusina kushandiswa)
- Kumisa rupture
- Wrinkling
- Asymmetry
- Kupisa
- Pain
- Kurwara
Iyo FDA inonyorawo hutsika hwakanyanya asi huchiwedzera hwekuongororwa neaplastic large cell lymphoma (ALCL).
Recent Trends in Process Procedures:
Maererano nehuwandu hwemapareji wegore negore neAmerica Society yeAesthetic Plastic Surgery, chirongwa chekuvhiya chakaona kukosha kunowedzera muna 2016 chaisanganisira:
- Mafuta anotumirwa kumazamu (kumusoro 41 muzana)
- Labiaplasty (kumusoro 23 muzana)
- Bhuku rinosimudza (kumusoro 21 muzana)
- Mafuta anotamira kune chiso (kumusoro 17 muzana)
- Bhiza rinoshandiswa kubviswa (kumusoro kwekutanga 13)
Hazvizivikanwi kuti zvakadini ruzivo pamusoro pekuchengetedza lymphoma kwakakonzera kukwidziridzwa mukubviswa kwemafupa emvere.
Chii Chinozivikanwa NezveBermin Lymphoma, MuGumi?
Nhengo dzepamuviri dzemazamu, izvo zvinoreva kuti lymphomas inotanga kukura mumazamu, inonyanya kukonzerwa nekenza, inomiririra inenge 0.5 muzana yematambudziko echepere uye 2 muzana yematambudziko eexranodal lymphomas .
Dzinotanga mumatumbu e-lymphoid emuzamu-ezvo uye kuparadzira kwemasero machena eropa-ayo akakomberedza mahara uye lobes, uye mazhinji emaronda aya anomuka kunze kwemasero machena eropa anozivikanwa seB-seli . B-masero ndiwo rudzi rwemachena masero eropa ayo dzimwe nguva anogona kushandiswa uye aparadzanise mumasero eplasma anogadzira anorifomu emuviri wesimba.
Mishonga inobva kune imwe mhando yeropa rega rega, T-seli, hazvishamisiwo zvakare.
Avhareji yemakore paanotanga zve primary primary lymphoma makore 57. Mune zviratidzo zvinoratidza kuti mukadzi angave, kana kuti zvinowanikwa pamammograms uye kuongorora, primary breast lymphomas inonyanya kufanana nedzimwe mvere dzemazamu , saka kuongororwa kwakakosha kushandiswa kwezvirwere (immunohistochemistry) zvakakosha kuongororwa kwezviremera izvi. Asi maronda anowanzova asina kuroorwa, kana oga, uye akanaka chaizvo anorondedzerwa, uye anonzi ane unhu hwakasununguka kwavari.
Chii Chinozivikanwa Pamusoro peAnaplastic Large Cell Lymphoma? (ALCL)
Lymphomas inonyanya kuiswa seHodgkin uye isiri Hodgkin lymphoma, uye zvakare ne subtypes, kana wakaziva chikamu chikuru. Anaplastic huru cell lymphoma , kana ALCL, rudzi rwusingawaniki rweHodgkin lymphoma yeT cells. Icho chiduku chiduku zvikuru chechipiri paunenge uchitaura nezvesiriyo Hodgkin lymphomas, uye inomiririra anenge 3 muzana yevose vasina Hodgkin lymphoma matambudziko.
Kufarira uye kutsvakurudza kuAllic kwakasimbiswa mumakore achangopfuura nemishumo yezviitiko zvekutanga mazamu masymymasi anoenderana nesirine uye silicone mazamu. Muzviitiko izvi, chiitiko chinowanzoitwa ndechekuti chimwe chinhu chakaita kuvhiyiwa, izvo zvakaita kuti kuongororwa kwe lymphoma. Kana chero zviitiko zve lymphoma zvichionekwa kuti vasati vambovhiyiwa, izvi hazvina kuziviswa zvakanyanya.
Zvave zvichifungidzirwa kuti mungozi yekuwana ALCL ndeye1 muzana 500 000 vakadzi vane mazamu emvere. Nguva iyo inotanga kuonekwa inenge iri pakati pemakore 34 nemakore 59, uye kenza inoratidzika inokura mukati memakore anenge 3-7 kubvira panguva yekuzora maitiro.
Nyaya yekutanga yezvakaberekwa-inonzi ALCL yakabatanidzwa muna 1997. Mukutaurirana kwegore ra2013, makumi matanhatu ematambudziko eAlliance akabatanidzwa nekumisa akasimbiswa. Kubva panguva iyoyo, nhamba yematambudziko eAlc yakawedzera, sezvine nhamba yekumwisa mazamu.
IA ALCL inokanganisa kapsule yakagadzirwa nepamusoro pese inogadzirwa, kunyange zvazvo pane imwe nguva kune simba rakasimba, uye haritauri mhuka dzemazamu, pachayo. Muzviitiko zvakawanda, lymphoma inotanga nekusanganiswa kwemvura inenge isingaendi neyoga, zvichida ne shrinkage ye capsule yakapoteredza kuiswa, kana kuti mashoma kune rumwe rutivi rwekuisa.
Mamwe Mamwe Dhipatimendi reDeam:
Kubva munaFebruary 2017, FDA yakati:
FDA yakagamuchira zvikamu makumi matatu nemakumi matatu nemakumi matatu zvemakiriniki emakirini emakirini emakwenzi emishonga anogadziriswa-anosanganisira amaplastic huru cell lymphoma, kusanganisira kufa kwepfumbamwe. Pane makumi maviri nemazana maviri nemakumi maviri nematanhatu ane nhoroondo ne data pamusoro pehuwandu hwemashoko panguva yekubika. Pakati pezvi, makumi maviri nemakumi maviri nemakumi maviri nemakumi maviri nemakumi maviri nemakumi maviri nemakumi mana nemasere pakumiswa kwemavara. Iko kune mapeji 312 nedheta pamusoro pekuisa mbeu yekuzadza. Pakati peizvi, 186 yakashuma kushandiswa kwesilicone gel-filled implants, uye 126 yakashuma kushandiswa kwezvipfumwe zvakakwana zve saline.
Zvisinei, zvinoratidzika kuti zvichiri kusava nechokwadi pamusoro pezvinodiwa nemishumo iyi, maererano nehuwandu hwemudzimai ane zvirwere:
Nyaya iyi, apo MDR system inokosha inopa ruzivo, izvi zvisingatauriki kutarisa zvinokanganisa, kusanganisira zvisingakwanisi, zvisina kururama, zvisingatarisirwi, zvisina kufanirwa, kana kuti zvakashata mumatare. Mukuwedzera, chiitiko kana kupararira kwechiitiko hachigoni kutsanangurwa kubva kune iyi inongororwa yehupfumi chete nekuda kwezvingaitika pasi pekupa ruzivo, kudzokorora ruzivo rwezviitiko, nekushaikwa kweruzivo pamusoro pehuwandu hwehuwandu hwemafupa emvere.
Shoko Rinobva
Iyo FDA inopfupikisa mabhuku ezvokurapa panyaya iyi, zvichiratidza kuti zvese zvemashoko kusvika zvino zvinoratidza kuti vakadzi vane mazamu emvere vane hutsika zvakanyanya asi huwandu hwekuwedzera ALCL huenzaniswa nevakadzi vasingasviki mazamu.
Vanocherechedza kuti maitiro akawanda ezvokuita mazamu-anonzi ALCL anoshandiswa nekubviswa kwekusimudza uye capsule yakapoteredza kuiswa uye mamwe maitiro ave achibatwa ne chemotherapy uye mahara. Nhungamiro ye 2017 kuvarapi vezvehutano maererano neprophylactic yokususwa haisi yakasiyana zvikuru nekudzoka kwekare:
"Nokuti inowanzove yakarongerwa kune varwere vane nguva yekupedzisira yezviratidzo zvakadai sekurwadziwa, kumira, kuzvimba, kana kuperesa, prophylactic kunyanya kushandiswa kubva kune varwere vasina zviratidzo kana zvimwe zvisina kufanira hazvibvumirwi."
I-FDA inokurudzira kuti kana uine mazamu emvere, hapana chikonzero chekuchinja mararamiro ako nguva dzose uye kutevedza, kuti BIA-ALCL haigoni, uye kunyange isiri yakananga kuBIA-ALCL, unofanira kutevera mazano ekurapa akadai anosanganisira:
- Tevedzera mirayiridzo yechiremba wako kuti ungatarisa sei mazamu ako emazamu.
- Kana ukacherechedza chero shanduko, taura nevhutano wako wekuchengeta utano nokukurumidza kuronga kusangana.
- Iva netsika yekuongorora mammography nekukumbira teknolojia inonyatsodzidziswa mukuita mammograms kune varwere vane mazamu emvere.
- Kana iwe une silicone yakazara-mazai ezvokuita mazamu, ona nguva yakareba magnetic resonance imaging (MRI) kuti uone kuputsika sezvakakurudzirwa nemutapi wako wehutano.
- Dhiyabhorosi inogamuchirwa neDAA inogadziriswa yeilicone-gel-filled filled implants inotaura kuti MRI yekutanga inofanira kuitika makore matatu mushure mokuvhiyiwa kwemajeri uye makore maviri pashure pacho.
Mune mutauro wakataurirwa kuvarwere uye vakadzi vachifunga nezvemafuro emvere, FDA zvinonetsa kuva nehurukuro yakanaka nachiremba wenyu pamusoro pezviitiko zvinozivikanwa zvezvipimo vasati vasvika.
> Sources:
> Fleury E de FC, Rêgo MM, Ramalho LC, et al. Silicone-induced granuloma yemazamu kuisa capsule (SIGBIC): kufanana uye kusiyana kweplastiki yakakura sero lymphoma (ALCL) uye kusiyanisa kwavo kusiyanisa. Chirwere chepabonde: Target uye Therapy. 2017; 9: 133-140.
> United States Zvokudya uye Drug Administration. Anaplastic Large Cell Lymphoma (ALCL) Madzimai ane Breast Implants: Preliminary FDA Kutsvaga nekuongorora.
> United States Zvokudya uye Drug Administration. Breast Implant-Yakabatanidzwa Anaplastic Large Cell Lymphoma (BIA-ALCL).