Kusvika pandinenge ndichiziva, hapana chinhu chakadai sehutano hwakanaka hweuropi. Izvozvo zvakati, kazhinji nguva meningioma inenge yakakosha sechirwere chepfungwa sezvaunogona kuwana. Ichokwadi, mune dzimwe nzira, hazvirevi kunyange sechirwere chepfungwa.
Chii Chinonzi Meningioma?
Kunyange zvazvo meningiomas inowanzotaridzirwa sepfungwa yepfungwa yepamusoro , ndakashandisa zvinyorwa zvepamusoro nekuti technically a meningioma haisi chirwere chemakumbo ehupi zvachose.
Panzvimbo pacho, meningioma inokura kubva kumangwanani, mishonga inodzivirira yakapoteredza uropi. Kunyanya, meningiomas kazhinji inobva kune arachnoid mater .
Minyengetero inotevera hutano hukuru huno. Semuenzaniso, meninges anoenderera mberi nechepakati peuropi apo nzvimbo yakasara uye yakarurama hemisphere inoparadzaniswa, uye inoputira pasi pedenga rehenya uye maziso emagetsi. Zviratidzo uye kurapwa kwevanhu meningioma zvishoma zvinotenderera pane nzvimbo yechipfuva.
Maitiro Anowanikwa Sei Meningiomas?
Kunyange zvazvo kuongorora kwevanhu vanopfuura 2 000 pamotokari kwakaratidza kuti vanenge 1 muzana yevanhu vangave vane meningioma, havasi ivo vanowanzoongororwa muhupenyu. Maviri acho anogona kukura zvishoma, dzimwe nguva zvakaoma zvachose.
Maererano neCentral Brain Tumor Registry muUnited States (CBTRUS), kufungidzirwa kwehuwandu hwevanhu meningioma muUnited States inenge 170 000 vanhu. Kubva pane idzi nhamba, meningiomas ndeimwe yezvakanyanya kufanana nemakumbo ose europi, kuverenga kwechetatu chezviitiko.
Kana meningiomas inokonzera zvinetso, inowanzorapwa nekuvhiya uye nyore nyore. Izvozvo zvakati, meningiomas dzimwe nguva ingave yakakomba kana kunyange kutyisidzira upenyu. Misiyano iri mumhando uye nzvimbo ye meningioma, pamwe chete neunhu hwakasiyana nevamwe vanhu.
Ngozi
Zvimwe ngozi kune meningioma haigoni kubatsirwa.
Somuenzaniso, meningiomas inowanikwa kaviri inowanzoonekwa kune vakadzi kana ichienzaniswa nevarume. Chiitiko chevanhuingi chinowedzera nezera. Izvo zvisinganzwisisiki muvana asi zvinogona kunge zvakanyanya kufanana nehutachiona tsvina inowanikwa kune vanhu vanopfuura makore 85.
Kunewo mazita ehutachiona hunokonzera varumeingioma. Inonyanya kuzivikanwa neurourobibromatosis type II, iyo inowedzera mikana yeumwe munhu kuwana mazamu akawanda. Iyi syndrome inokonzerwa nekuchinja kweNF2 gene , iyo inowanzobatsira kubvisa matumbo. Mamwe mazai akabatanidzwa mu meningioma ari DAL1, AKT1, uye TRAF7.
Radiation ndiyo inonyanya kushandiswa inogadzirisa ngozi inowanikwa yevarumeomaoma. Izvi zvakanyatsodzidza mumamiriro ezvinhu apo uropi hwave huri kuratidzirwa mukurapa kenza yakasiyana. Sezvo kunogona kuva nguva yakareba pakati penguva yemirairo uye kuwanikwa kwevarumeomaoma, njodzi inopfuura yevana. Semuenzaniso, mukudzidza kwevanhu 49 avo vaiva nehutachiona hwekuberekwa nehutano hwakabatwa nemirairo, 11 vakange vane meningiomas mushure mekuwandisa nguva yemakore 25. Mazairo nemaitiro ezvokurapa akadai semayenzi e-X-rays akadzika kwazvo, kunyange zvazvo zvidzidzo zvakaratidza kuwirirana pakati pekushandisa kwenguva refu X-ray uye gare gare meningioma kukura.
Zvimwe zvinogona kuisa mungozi ye meningioma zvakadzidzwa nemigumisiro inopesana, kusanganisira kurema, hormone replacement, uye kushungurudza musoro.
Chii Chinogadzira Meningioma Zvikuru?
Kunyange zvazvo vakawanda meningiomas vane urombo chaizvo sekuda kudzivisa kuonekwa, vanogona kunge vakaoma zvakanyanya. World Health Organization yakarongedza meningiomas muzvikamu zvitatu zvichienderana nechitarisiko chavo pasi pe microscope. Izvo zvakanyanya kufambira mberi mukirasi, inowedzera meningomaoma.
- WHO Bhuku 1: Gira I I meningiomas inonyanya kuipa. Kunyange zvazvo vachiri kungoda kuvhiyiwa kuti varege kuomeswa kwezvivako zvakakosha zvehuropi, kazhinji hapana chimwe chinhu chinodiwa pane nguva periodic neuroimaging zvidzidzo kuitira kuti zvive nechokwadi kuti hazvive zvakakura zvikuru.
- WHO Grade 2: Iyi meningiomas ine zviratidzo zvakawanda zvekushanda kwema cell division. Kuchenjerera kwakanyanya kunofanira kutorwa nezviremara izvi. Zvikamu zvinosanganisira chordoid, sero yakachena, uye atypical meningiomas.
- WHO Grade 3: Izvi zviputi zvine zviratidzo zvakawanda zvekushanda kwema cell division. Dumbu racho ringangodaro richipinza mukati mehupi kana kuratidza nzvimbo dzerufu kufa. Zvikamu zvinosanganisira papillary, rhabdoid uye amaplastic meningiomas. Chero 2 kusvika ku3 muzana yevarume voseomas Grade 3.
Varwere vane matanho akakwirira evarumeomomas vanowanzove nekudzokorora kwevarumeoma mushure mokurapa uye vanowanzova nehuwandu hwekufa kwevose. Kusununguka kwemakore mashanu-kusina kusununguka muchechi II meningioma yakatsanangurwa pa 87 muzana ichienzaniswa ne29 muzana yegore III.
Pasinei nemhando yevarumeoma, nzvimbo nehukuru zvinogona kuva zvakakosha pakusarudza kudiwa nekukurumidza kwekurapa. Chinonyanya kukosha, zvakadaro, ndeyekuti munhu ane meningioma ari kuita sei muupenyu hwavo hwezuva nezuva.
Sources:
Banerjee J, Pääkkö E, Harila M, et al. Radiation-induced meningiomas: mumvuri mukubudirira nyaya yehutano hwehutano. Neuro Oncol 2009; 11: 543.
Claus EB, Bondy ML, Schildkraut JM, et al. Epidemiology yepractical meningioma. Neurosurgery 2005; 57: 1088.
Wrensch, M, Minn, Y, Chew, T, et al. Epidemiology yepfungwa dzepfungwa dzepfungwa dzepamusoro: Current concepts nekudzokororwa kwemabhuku. Neuro-Oncology 2002; 4: 278.
Yang SY, Park CK, Park SH, et al. Atypical and amaplastic meningiomas: kufungidzira kunofanirwa kwekliniki epathological features. J Neurol Neurosurg Psychiatry 2008; 79: 574.