Axumin inonzi FDA-inogamuchirwa, Medicare-yakafukidzirwa scan iyo inogona kusvika pakuonekwa kwenguva refu kwekenza yenguva yakawanda yeprostate mushure mekuvhiyiwa kana kupiswa kwezuva. Kwemakore tave tichikwanisa kuona kenza yeprotate yakadzoka nePSA , asi muviri wakazara uye mapfupa emapfupa akange asingakwanisi kugona nzvimbo yekenza kusvikira PSA iri yakakwirira zvakanyanya (10 kusvika ku30 kana kupfuura).
Axumin inogona kuona chirwere chinowanzoitika nemazinga ePSA pasi pe10 uye dzimwe nguva zvakaderedza zvakanyanya, ndicho chikonzero ichi kuongorora chinhu chakakosha kukura.
Nei Chiratidzo Chinokosha Kwazvo?
Kuva akakwanisa kuona zvirwere zvekutanga zvemasastati ne scan zvinopa mbiri inokosha kurapa kunobatsira. Kutanga, ruzivo rwekupi kenza iripo inogona kubatsira kutungamirira kurapa kwakanaka kune imwe nzvimbo yemuviri uye kugadzirisa kukanganisa kune dzimwe nzvimbo dzomuviri. Nhandare inoona kuti kenza haina kupi uye kuti kurapwa hakudi.
Chechipiri chipo chinokosha icho chinonyatsoongorora chinopa kujekesa kwakadzama muchirwere ichi pachako-kuzarura kana kanhi kana kuti kwete chekenza yakagadziriswa, uye kana yakagadziriswa, kusvika pakadini.
Kanzera inopararira inoratidzwa nePSA inokura haisi nguva dzose nekuda kwemasimasita. Dzimwe nguva kenza inogara iri pedyo kana kuti kwaivepi iyo prostate yaimbova iyo, saka PSA iri kuuya kubva kumuchirwere inowedzera mu prostate gland mushure memasikati kana mu prostate fossa mushure mekuvhiyiwa (fossa ndiyo nzvimbo yemuviri apo prostate yakanga iripo kubviswa kushandiswa), iyo inozivikanwa se "kudzoka kwekugara."
PSA inogonawo kukwidziridzwa pamusana pokukura kwekenza iyo yakagadziriswa kune lymph nodes kana mapfupa. Izvi zvinonzi "systemic kudzoka zvakare." Kudzokorora kwakagadzikana kunonyanya kutyisa kudarika kudzokorora kwenharaunda. Sei? Maitiro anoratidza kuti kenza ine simba re biologic kupararira kumativi ose mumuviri-chirongwa chinotungamirira kurufu mune zvinopfuura hafu yekenza yekenza yeprostate.
Nokudaro, kuziva nzvimbo yekudzoka mhinduro inobvunza mubvunzo unokosha zvikuru: ingave zvirwere zvinowanzoitika zvinotyisa zvakakwana kuderedza mhuka.
Sezvatareva, kukwanisa kwekenza kupararira ndicho chinoita kuti kenza ive yengozi. Idzi ruzivo runosunungura chiremba kuti aite zvinotyisa zvekurapa protocol kunze kwekuchengetedzwa kwakabatana nekutya kwekuporesa kupfuura. Kana chirwere chinowanzoitika chinowanikwa panzvimbo yeprostate kana prostate fossa, nzira yakadaro yekutsamwisa ingadai isingabvumirwi uye isingabviri.
Mishonga ine utsinye inogona kuwirirana nemigumisiro yakakomba. Zvisinei, rudzi rwemishonga inoshungurudza yandinenge ndichitaura ndeyemishonga inopararira muropa uye ine simba rinopisa mumuviri wose, iyo iyo chemotherapy neHototere kana hormonal therapy neLupron neCodeodex ndiyo mienzaniso yakanaka.
Nhume Inobata Sei?
Mafupa emapfupa akaenzana anoshandisa calcium-yakabatana radioactive zvinhu zvinowedzera munzvimbo dzefupa dzinoshungurudzwa nekenza. IAxumin PET scan inoshanda nekuona basa remagetsi rekenza pachayo .
Axumin inoshandisa kuti kenza yeprostate inotora amino acids pamwero wakakurumidza kukunda masero.
Axumin inosanganisira inonzi radioactive tracer inosanganiswa neamino acid. Sezvo kenza yemaseya inobata amino acids zvakanyanyisa kupfuura masero ezvakaberekwa, majekesa anoisa mukati memarara emasero. Apo murwere akaiswa pasi pe scanner nzvimbo yenzvimbo dzakakwirira dzemahara dzinoratidza chiratidzo chekenza mumuviri wemurwere.
Nhoroondo Idzva Inopiwa Sei NeAxumin Inoshandiswa?
IAxumin scan inogamuchirwa kune varume vakagadzira PSA inokura mushure mekunge majekesa kana kupera. Nhoroondo yekare, shoma pfupa inoshandiswa uye CAT inoongorora inoda mazinga ePSA mu 10 kusvika ku50 yakatarisana musati wakakwana wekenza yaizovapo kuti ionekwe pakutsvaga.
Kunaka kweAxumin PET kuongorora ndeyekuti inopa mikana yekuona zviduku zviduku zvinoshandiswa mumakirini ane nhengo dzePSA mumutambo we1 kusvika ku10.
Imwe nzira inogona kushandiswa yeAxumin scan, kunze kwekubatsira kwayo pakusarudza nzvimbo yePSA kudzokerazve, ndeyevarume vakawana chirwere chemo-hormonal chechirwere chetachiona chepamusoro. Mushure mokurapa, varume vanogona kuwana kupera kwakakosha muPSA-zvichida kubva pa100 kusvika kune gumi kana pasi. IAxumin scan inogona kuisa nzvimbo yekenza mumuviri uri kuratidza kushandiswa kwemaitiro emagetsi, chiratidzo chokuti kenza dzemasero dzinoramba dzichishanda pasinei nekurapwa kwekare neLupron uye Taxotere. Kana imwe nhamba shoma yezvinhu zvinoramba zvichisanganiswa, zvinogoneka kuti varwere vakadaro vanogona kubatsirwa nemirairo yepavara kana mamwe maitiro ekurapa anotarirwa kune zvakasara zvirwere.
Future Futures
Kunyange zvazvo kuongorora kwave kwekutanga kugamuchirwa kushandiswa mukugadzirisa kwePSAzve , mamwe maitiro angangoshandiswa munguva yemberi. Mukuru wepanyika angave ari kuenzanisa varume vanenge vachangobva kuongororwa neGleason zvikamu zve8 kana kupfuura kana kuti varume vane PSA dzakakwirira kumusoro. 20. Kucherechedza zvirwere zvepakutanga zvekare mumakirini emadzimai muvanhu vachangobva kuongororwa chinhu chakakosha. Varwere vane zvirwere zvinonzi metastatic vakaona kuti vakanyanya kurapa mazinga kana vakagamuchira kurapwa kwehasha ne Taxotere uye Lupron. Varwere vasina rusununguko rwemasastasis akadaro vanogona kutora zvirwere zvekare uye vanogadzirisa migumisiro yavo pasina kuderedza kurapa kwavo.
Kududzira zvinyorwa
Kutsanangurwa kwezvinhu izvi zvitsva zvinosanganisira kuisa ruzivo rwekudzidza kune vanachiremba vanoverenga kuongorora. Iyi ndiyo mamiriro nemhando ipi zvayo yeukamera. Zvakakoshawo kuti varwere vaone kuti rudzi rwe teknolojia yekuita zvinhu izvozvi-kureva, ma scanners pachavo-achasiyana kubva kumitambo yekuita. Mimwe miitiro ine teknolojia yakare uye simba rekuona zvidiki zvitsuwa zvinenge zvisingasviki.
Kuziva zvikonzero izvi zvinokonzera, zvichave zvakakosha kuvarwere kuti vaone nzvimbo dzinoshandiswa nehuni-ye-ye-yezvigadzirwa zvehutano uye dzave dzichiona vanachiremba vari kuita nhamba huru yekuongorora. Iyi nzvimbo dzepamusoro dzinogona kunge dzichiziva zvakawanda kuverenga idzi zviyero zvakanaka.
Kushanda Kuisa-mu-Maoko Nezvimwe Ikombiji
Chimwe chikonzero nei Axumin ichibudirira zvinokosha ndechokuti inobatsira vanachiremba kushandisa zvese zvakakwana zveUnited Modulated Radiation Therapy (IMRT). IMRT inonyanya kunyatsorudzika yehutaneti hwehutachiona hunogona kutarisa nzvimbo dzakawanda dzomuviri dzakanga dzisati dzisingakwanisi kujekesa. IMRT yakarurama kwazvo zvokuti vanachiremba vanogona kuronga dhidhiro yeganda ne millimeter yakarurama uye zvachose kudzivisa kukanganisa kune zvakanyatsorongeka zvivako zvakadai sematumbu, somuenzaniso, kune varwere vane chirwere chemuviri chinonzi lymph node mumimba. Chimwe chezvikonzero nei Axumin PET kuongorora ichifadza zvikuru nokuti inonyanya kuita imwe teknolojia yakagadzirwa, IMRT, iyo inobatsira zvikuru.
Tariro Yakawedzerwa Yenguva Yemberi
Kuuya kwekuvandudzwa kwekenza kupenya neAxumin kunowedzera tariro yokuti mamwe marudzi matsva ekutsvaga kupenya ari kuuya munguva inotevera. Somuenzaniso, mamwe mhando dzePET inoongorora, imwe inowanzonzi PSMA, inotarisira imwe molecule inowanzoonekwa pamusoro pekenza yekenza yeprostate. Izvo zvinogona kubatsira PSMA zvinowedzera kunze kwekubatsira kwekufungidzira; iyo inogona kuita shanduro yekurapa zvakare. PSMA ligands inogona kubatanidzwa kune mamwe ane simba anokonzerwa nemavhudhiki ane simba zvakakwana kuti auraye masero emukenza.
Mharaunda yekenza yeprostate yakamirira kutarisa kuongorora maitiro ekenza yeprostate mumuviri nehuwandu hwehutano hwekuti zviratidzo zvePET zvinogona kubudirira. Izvi zvinomiririra kushamisa kunoshamisa. Iye zvino kuti FDA yakabvumira teknolojia iyi, makambani einishuwarenzi anotanga kutsvaga nzira dzekupa kugoverwa. Medicare ndiyo yaiva yekambani yeupurivisi kambani yekuifukidza.
Chii Chiri Kupera Kare?
Axumin ndiyo ingangodaro yakawanda yekenza yeprostate inopera muna 2017, asi iwe unganetseka zvakare pamusoro pezviitiko zvakakosha mumakore matatu apfuura. Chokutanga, kukurumidza kukurumidza kwekuwanikwa kutsva ndiko kukura kwechitsva, asi zvimwe zvakabudirira zvinosanganisira:
Sei Kubudirira Kunowedzera Zvakawanda?
Chikonzero chekukurumidza muhuwandu hwekubudirira ndiko kuguma kwekutsvakurudza kwakadzama kwekutanga kunotungamirira kunzwisisa kwakadzama kwemajeri yekenza yeprotate. Kunyanya zvakananga, zvakananga kuchinja kwemagetsi izvo zvinokonzera kusadzorwe kushandiswa kwemasero zvakanatswa.
Majini anogadziriswa ndiwo anoita kuti masero emukenza akasiyana nemasero akajairika. Iye zvino kuti kuchinja uku kunogona kuonekwa, mushonga mutsva unogona kugadzirirwa kubhadharisa maitiro easina kushanda. Funga nezvekuti patch software ingave yakanyorwa sei nekombiyuta purogiramu yekugadzirisa kombiyuta.
Mumakore apfuura, tisati tasvika pakunzwisisa kwedu kwemazuva ano kwemajeri ejeri, mishonga mitsva yaiva mugumisiro wekuoma, kuedza uye kukanganisa kukura. Ikemikari yakasarudzwa yakasarudzwa yaizoendeswa kune kenza yemumera inokura muPetri ndiro. Kana kemikemikari ichiita kuti masero ekenza afe, aizotarisirwa kune mhuka ine kenza. Kana kenza yakagadziriswa uye mhuka ichigara, yaizoedzwa kuvanhu. Kubudirira kwevanhu miedzo kwaizobva kwaita kuti FDA igamuchirwe uye kuwanika kwekodzero kwehutano hutsva.
Kusiyana nemishonga yakagadzirirwa yakagadzirwa munguva pfupi yapfuura, nzira iyo mishonga iyi yakawanikwa nekuedza uye kukanganisa basa yakanga isingazivikanwi.