Amitiza (lubiprostone) mishonga iyo FDA-inogamuchirwa kuitira kurapwa kwechirwere chinonzi idiopathic constipation (CIC) muvanhu vakuru uye kuvimbiswa zvikuru kweBS (IBS-C) kuvakadzi vanopfuura makore gumi nemasere. Amitiza mishonga inonzwika ine murwere kuitika.
Amitiza Inoshanda Sei?
Amitiza inokurudzira kusunungurwa kwemvura mukati mechidzitiro chemukati.
Inofungidzirwa kuti izvi zvinowedzera kushandiswa kwemhepo kunodzikisa chigaro uye kunoderedza chigaro chekutengesa nguva , nekudaro kubvisa zviratidzo zvekudzivirira. Amitiza migumisiro inofungidzirwa kuti igare inenge iri mukati memukati wemukati.
ImaAmitiza Inoshanda Here?
IAmerican College of Gastroenterology muna 2014 inongororo yekutsvakurudza, inoratidzira zvakasimba shandiso yekusimbisa kwekubudirira kweAmitiza mukudzivirira kubatwa. Amitiza yakaratidzwa ku:
- Wedzera chigaro chepamusoro
- Itai zvimwe zvakagadzikana, zvakagadzirwa zvakanaka
- Deredza kudzvinyirira uye kusina kukwana kwekuvhara kwemukoko
- Kuderedza marwadzo emimba uye kusagadzikana
Ndiani asingafaniri kutora Amitiza
Iwe haufaniri kutora Amitiza kana uri kutarisana nezviratidzo zvekurambana kana chirwere chekudzivirira. Vakadzi vari kuyamwisa vanofanira kungotora Amitiza pasi pekutarisirwa kwechiremba wavo. Amitiza haina kubvumidzwa kuti ishandiswe muvana.
Migumisiro Yechiratidzo yeAmitiza
Amitiza inowanzochengetedzwa zvakanaka uye yakaipa migumisiro inowanika.
Izvi zvinotevera migumisiro yakataurwa:
- Nausea
- Diarrhea
- Headache
- Abdominal distension
- Urinary tract infection
- Sinusitis
Nausea inobatanidza neAmitiza haisi chiitiko chisingawanzoitiki: Inofungidzirwa kuti 19 kusvika ku29% yevashandisi veAmitiza vanoona nhamo. Kuti uderedze njodzi yekutsvaga tsvina, zvinokurudzirwa kuti utore mishonga pamwe nechingwa.
Sources:
Carter, N. & Scott L. "Lubiprostone: mukuzvidzivirira-kunonyanya kunetseka nehowel syndrome." Zvinodhaka 2009 69: 1229-1237.
Chey, W., et.al. "Kuchengetedza uye zvinokonzera chirwere pamwe neLibiprostone kwevhiki dzinosvika makumi mashanu nemapfumbamwe kune varwere vane shungu dzehuwel syndrome nechisungo" Alimentary Pharmacology and Therapeutics 2012 35: 587-599.
Ford, A., etal. " American College of Gastroenterology Monograph paKutonga kweIriritable Bowel Syndrome uye Chronic Idiopathic Constipation " American Journal of Gastroenterology 2014 109: S2-S26.
Gamani, A., Bucur, M. & Kuo, B. Kurapa kwehutano mukushanda kwehutachiona hwehutachiona: hurumende yemukirwere yemishonga Inhepeutic Kufambira mberi muGastroenterology 2009 2: 169-181.
Johnston, J. et.al. "Pilot Study pamusoro pemigumisiro yeLinaclotide muvarwere vane chinyararire chekuchengetwa kwemazuva ano" American Journal of Gastroenterology 2009 104: 125-132.
Lacy, B. & Chey, W. "Lubiprostone: chisingararamiro chikafu uye chinoshungurudza chirwere chemafupa nekudzivirira.
Lacy, B., Weiser, K. & Lee, R. Kurapa kwekutsamwisa kwemafupa echirwere Therapeutic Achivances muGastroenterology 2009 2: 221 - 238.