Is Xopenex iri nani kupfuura Albuterol?
Xopenex (levalbuterol) imishonga inoputika yekurapwa kwezviratidzo zvakanyanya zvechirwere , kusanganisira kuora, kusvetuka, kufema kwepfufu uye chifuva chisimbiso. Xopenex inoshandisa nekudzikinura misoro inotapira mumapapu, kazhinji mumaminitsi mashomanana ekutora mishonga. Xopenex inowanikwa zvose se inhaler uye mune imwe nzira yekugadziriswa yakapiwa nebulizer machine.
Xopenex ndiyo inosangana ne- albuterol (inonzi R-albuterol kana levalbuterol). Maikemikari matsva emishonga anovapo sechisanganiso chezvioni zvegiratiro kune umwe (zvinonzi sechisimba chinosanganiswa ), uye imwe chete yemhando iyi ndiyo inoshandiswa mushonga. Nzira isina kushandiswa (inonzi S-albuterol kana dextroalbuterol) haishandisi chinangwa kunze kwekuti "inowanikwa" yefomu inoshandiswa uye inogona kunge ichibatsira kune migumisiro. Ichi chaiva chinangwa chekuti nei Xopenex yakagadzirwa - kuvandudza basa reAlubuterol nekuderedza migumisiro yechirwere.
Is Xopenex Iri nani kupfuura Albuterol for Asthma?
Hazvisi zvachose zvakajeka. Apo Xopenex yakatanga kukurudzirwa, zvidzidzo zvemhuka zvakaratidza kuti S-albuterol yakakonzera kuvhiringidza mumapapu, izvo zvingangoderedza kuwedzera mweya. Izvo zvaifungidzirwawo kuti sezvakanyanya kukonzera albuterol (musanganiswa weR uye S-albuterol isomers) yakatorwa, s-albuterol mutsara ingangounganidza mukati memapapu uye inokonzera kukanganiswa kwemisumbu yakanyorova kumativi emapapu, zvichiita kuti kuwedzere zviratidzo zvechirwere .
Saka Xopenex aitarisira kushanda zvakanaka mukurapa zviratidzo zvechirwere kupfuura racemic albuterol.
Zvidzidzo zvepakutanga zvakaratidza kuti Xopenex yakanga iri nani pakurapa chirwere chinonzi albuterol, sezvo zvishoma zvishoma Xopenex zvaidiwa kuti zvive nekugadzirisa zviratidzo zvechirwere pane zvakaenzana zvakaenzana neAluterol. Sezvo Xopenex iri hafu inoshandiswa yeAluteruterol, mumwe angatarisira kuti hafu yeiyo ye Xopenex yaizoenzana nehuwandu hwechirwere che albuterol; zvisinei, zvidzidzo izvi zvakaratidza kuti chikamu chechina chete chechirwere che-albuterol chaidiwa kuti chibudirire chiitiko chimwechete apo uchishandisa Xopenex.
Izvi zvaifungidzirwa kuti ndezvikonzero nekuda kwekushayikwa kweS-albuterol mutsva mu Xopenex, iyo yakanga iri kushanda neR-albuterol.
Nhau dzekare pamusoro pe Xopenex, zvisinei, pamwe chete nekupfupisa kwezvinhu zvose zviripo, zvinoratidza kuti Xopenex haisi nani pakurapa chirwere chinenge chisingadi kutarisirwa. Chirwere che Xopenex chinodiwa kuti chibudirire chiitiko chimwechete chekurapa chirwere chemafi chinoratidzika kunge chinenge hafu yehafu, izvo ndizvo zvinotarisirwa sezvo zvine chine simba chinoshanda (R-albuterol). Iyo S-albuterol inomiririra inoratidzika kuva ineriti, zvinoreva kuti haibatsiri kana kupikisa kurapwa kwezviratidzo zvechirwere.
IXopenex Inosara Zvishoma Here kune Albuterol?
Albuterol inonyatsozivikanwa kuti inokonzera mimwe migumisiro, kusanganisira kudengenyeka kwemasumbu, jitteriness, palpitations uye kuwedzerwa kwemwoyo. Zvidzidzo zvepakutanga zve Xopenex zvakaratidza kuti nokuti mishonga yakanyanya kudarika yaidiwa kuti iwane rubatsiro rumwechete seAlubuterol, zvishoma zvingazoitika. Mukuwedzera, pakutanga kwaifungidzira kuti S-albuterol mutsara waiva kunyanya kutarisira vazhinji veAluterol migumisiro, uye naizvozvo Xopenex, iyo isina S-albuterol inotyisa, inokonzera mashoma emigumisiro.
Zvidzidzo zvenguva pfupi zvinoratidza, zvisinei, kuti migumisiro yechirwere yeXopenex yakaenzana ne albuterol sezvo iri chaizvo R-albuterol mutsara iyo inokonzera albuterol migumisiro.
Iyo S-albuterol inomesa inert, zvinoreva kuti haibatsiri pamigumisiro. Pakavhara ye Xopenex inotaura kuti chiyero chezvikamu zvakataurwa pamusoro apa ndechimwechete zvakaenzana neiyo Xopenex uye albuterol.
Dzidza kuti ungashandisa nekuchenesa sei Xopenex inhaler .
Sources:
Xopenex package insert [PDF]. Sepracor corporation. Yakasvika musi waJanuary 13, 2011.
Ahrens R, Weinberger M. Levalbuterol uye Racemic Albuterol: Pane Kusiyana kwekurapa Here? J Allergy Clin Immunol. 2001; 108: 681-4.
Milgrom H, Skoner DP, Bensch G, et al. Low-Dose Levalbuterol muvana vane Asthma: Kuchengetedza uye Kubudirira mukuenzanisa nePainbo uye Racemic Albuterol. J Allergy Clin Immunol. 2001; 108: 938-45.
Lötvall J, Palmqvist M, Arvidsson P, uye al. The Therapeutic Ratio yeR-Albuterol inofananidzwa neyeRS-Albuterol muAvhmatic Patients. J Allergy Clin Immunol. 2001; 108: 681-4.