Iyo Dumbu Rinogadzira Sei Nzira Yekuonda-Kuita Bhakitiriya
Vanotambura vanotsanangura chirwere sechitsva, chinoputika, gnawing, kana kupera mudumbu chinouya mumafungu, kwemazuva matatu kusvika mana panguva imwe, asi inogona kuderedza zvachose kwemavhiki kana mwedzi. Marwadzo akaipisisa vasati vadya uye panguva yokurara apo mudumbu kazhinji hauna chinhu. Chirwere chacho pachako chinosuruvara mukati mechidzitiro chemuviri (gastric ulcer) kana muchikamu chepamusoro chemukati mudumbu, kana duodenum (duodenal ulcer).
Zvose zviri zviviri zvinonziwo peptic ulcers .
The Acidic Stomach: Kugadzirisa Matanho eUlcers
Dumbu ndicho chikamu chinonyanya kushamisa chemuviri, kuisa danho rekudzivirira kwechirwere uye utachiona. Mhando mitatu yemasero inoputira izvo zvinokonzera gastric juice: masero mucous-secreting, masero makuru anosunungura maitiro ezvokudya, uye masero emapetetal anobudisa hydrochloric acid . Masero-kuchengetedza masero anobudisawo histamine, iyo inoita kuti masero eparietal asunungure asidi. Dumbu inoda nzvimbo yeAic acid ye digestive enzyme pepsin kuputsa mapuroteni muzvokudya.
Acidity inotarwa achishandisa pH chikamu. A neutori pH haisi asi kana nheyo-inokosha ye7; acids vasingapfuuri 7, uye zvigaro (zvinonziwo alkaline zvinhu) zvinopfuura 7. Mvura zhinji yemuviri, kusanganisira ropa, misodzi, pancreatic juice, uye bile, iri munharaunda 7 kusvika ku8 pH. Gastric juice, zvakasiyana, ine pH ya 1.6 kusvika 1.8.
Izvozvo zvinowedzera acidic kupfuura juisi yemuori, cola zvinodhaka, uye kofi. Nzvimbo iri mumukati muduku yakanyanya kudarika kupfuura mudumbu, asi nokuti inogamuchira musanganiswa we-acidic wezvokudya zvakagadzirirwa kubva mudumbu, zvinowanzoita kuonda.
Mucheche mukati memukati, iyo mucosa, inodzivirira kubva pakuzvidzivirira.
Iko mucosa inosanganisira kuvhara masero, maitiro anobatana, uye musuru. Chironda chinoshungurudza kana chinopinda mucosa kupinda mumhepo inonzi submucosa, iyo inowedzera muropa uye nemidziyo yeropa.
Chirwere-Chinokonzera Bhakitiriya
Mhando ye churning acidic goop ingasaratidzika seyakagamuchirwa kwechirwere, asi mhando inokonzera ulcers ( H. pylori ) inowedzera muzasi pH. "Ivo vane mazita akasiyana-siyana anonzi flagella anovabvumira kupinda mumucheka wepamukati, umo pH inonyanya kushivirira. Kubvisa izvi mabhakitiriya hazvisi nyore," anodaro Dr. Gallo-Torres. Mishonga inorwisa mabhakitiriya inogona kukwanisa kuuraya mabhakitiriya, asiwo usaputsika kuputika munzvimbo dzakashata.
Vanotsvakurudza havazivi kuti vanhu vanowana sei mabhakitiriya. Zvisinei, kutengesa munhu-ku-munhu kunofungidzirwa kuti ndiyo inonyanya kufamba munzira dzakabudirira munyika. Munyika dzichiri kusimukira, kufambisa-kunyorera-kutaura kunogona kuita basa rinokosha, rakafanana nenzira iyo munhu anobata koriera uye hepatitis A.
Kurapa Zvironda, Zvadaro uye Zvino
Pakutanga kwezana remakore rechi20, chiremba chechirwere chaiva chivato chekuzorora uye kudya kwakashata, muchipatara kana murwere achigona kuzvipa. Antacids yakawedzerwa kuhurongwa hwekurapa apo vatsvakurudzi vakaziva kuti varwere vechirwere vanowedzera kudarika musimba asidi.
Pakazosvika 1971, nzvimbo yekudzivirira yevharesi yemaidhi yakawanikwa-histamine (H2) mutezo pamapetetal cells.
Apo histamine inosunga zvakagadzirwa zvakadaro, asidi inowedzera inowedzera. Zvine zvakagamuchirwa nemishonga yemaronda - Zantac (ranitidine), Tagamet (cimetidine), Pepcid (famotidine), uye Axid (nizatidine) -kuvhara H2 receptors, inokonzera chiratidzo ku secrete acid. Chipiri chechirwere chechirwere, chinonzi acid-kana proton-pump inhibitor, inoshanda pane imwe nzvimbo mukudya, ichivhara parietal masero kubva pakusunungura asidi. Prilosec (omeprazole) ndiyo chete acid-pump inhibitor inogamuchirwa muUnited States panguva ino yekurapa zvionda.
Dambudziko nemishonga inenge iripo ndeyokuti vanongogadzirisa zviratidzo zvishoma kwechinguva; chironda chinogona kudzoka. Ndokusaka mishonga inorwisa mabhakitiriya ndiyo mutsara wokudzivirirwa kwezvironda. Kana mabhakitiriya achiita zvimwe zvironda zvinopedzwa, zvakadaro, mikana yekudzoka kwechirwere zvishoma kudarika nokuti dambudziko rinorwiswa pane rayo.
Kunobva:
> National Digestive Diseases Information Clearinghouse (NDDIC) Chii Chandinofanira Kuziva Nezvepeptic Ulcers? NIH Publication Nha. 11-5042 - Yakapedzwa Gumiguru 2012.