Tsvakurudzo mune Zvokudya Zvokuwedzera zvinobatsira sei IBD Remains Inconclusive
Pakave nekuine huwandu hwakawanda hwekufungidzira kwakapoteredza kuti kudya kwakadini kunobata kufambisa uye nzira yezvokuvhiringidza zvirwere (IBD) . Zvinoratidzika kuti zvinonzwisisika kuti kudya kunogona kuva nemigumisiro kune chirwere chinokonzera zviratidzo mumugwagwa wekudya, asi kusvika ikozvino hakuna kuve huchapupu hunogombedzera hwekuti sei kana sei nei izvi zvingaitika, kana kana zvisingatomboiti.
Chikafu chinhu chinokurudzira, uye vanhu vane Crohn's disease uye ulcerative colitis ivo pachavo vanowedzera mari iyo kudya kunogona kuchinja kana kusakanganise zviratidzo zvavo. Sezvo ukama huripo pakati pekudya uye IBD huri kuongororwa zvakare, mamwe mazano pamusoro pehurukuro anowedzera kugadzira chimwe chekunzwa kana ichibudiswa.
Ukama huri pakati pehutachikiti (kuputika mumakoloni) uye kuwedzera kwezvokudya kunonzi titanium dioxide ndeimwe yakadaro. Parizvino hausi humwe uchapupu hunoti hukama pakati peBD uye titanium dioxide. Zvisinei, pane imwe tsvakurudzo yekutanga yekutanga iyo inogona kutungamirira kune zvimwe zvidzidzo kusvikira pane kunzwisisa kwakanakisisa kwokuti iyo marudzi ezvokudya zvinowedzera, izvo zvinogona kutaurirwawo sean nanoparticles kana microparticles, inogona kuwirirana neBDD. Parizvino, hapana mazano akawandisa kune vanhu vane IBD yekudzivirira zvokudya zvekuwedzera, uye vanhu vane IBD vane zvinetso vanofanira kubvunza chiremba wavo nezvekudya kwezvirongwa.
Chii chinonzi Titanium Dioxide?
Titanium dioxide (TiO2) inoshandiswa nanoparticle iyo inowedzera kushandiswa muzvokudya, mishonga, zvigadzirwa zvekutengesa, uye mishonga yekuchengetedza yega, yakadai sezvipfeko. Icho chinhu chakachena chingaita kuti michina ionekwe yakajeka kana yakachena, yakadai somufananidzo weziso, pfupa rakasununguka, pepa, kana kunyange cake frostings.
Titanium dioxide inoshandiswawo se UV (ultraviolet) filter mu sunscreens kudzivirira ganda kubva pakupisa kwezuva. Nokudaro, ichi chibereko chinopedzwa navanhu muzvokudya kana mishonga uye rinopfeka mumuviri uye rinopindira mukati meganda, zvakadai sezvipfeko kana sunscreens.
Apo titanium dioxide inoshandiswa mumishonga, inenge isingashandisi chigadzirwa , uye dzimwe nguva inonzi "excipient". Chigadzirwa chisingaiti chinogona kushandiswa mumishonga nokuda kwezvikonzero zvakasiyana-siyana, kana kuti "kubatsira" izvo zvinoshandiswa zvinoshandiswa kana kuti kuita mishonga kutarisa kana kuravira zviri nani. Inoshandiswa nokuti haifaniri kuva nechiito kune muviri.
Titanium dioxide inowanzoitika asi yakasikwawo munhu. Tsanangudzo yemakemikari ye titanium dioxide inogona kuve yakananga nokuti kune marudzi akasiyana. Vagadziri havakwanisi kutarisa rudzi rwetitanium dioxide rinoshandiswa mumiti, uye rine mazita akawanda ezvokutengeserana.
Yakachengeteka Sei Titanium Dioxide?
Titanium dioxide inogamuchirwa kuti ishandiswe muzvokudya, mishonga, uye zvipfeko, naizvozvo inonzi yakachengeteka nemasangano ehurumende akabvumidza kushandiswa kwayo. Mari inoshandiswa mumitambo ichasiyana, asi kazhinji haisi huru. Kushandiswa kwaro kumativi ose enyika kwakawedzera mumakore achangobva kupfuura, kunyanya muUnited States, uye inowanzove isina mari shoma.
Inofungidzirwa kuti vanhu vakuru muUnited States vangave vakagadzirirwa 1 mg ye titanium dioxide kilogram yehutemi hwezuva nezuva. Kune munhu anoyera, somuenzaniso, 150 lbs, iyo inenge iri 68 mg yekutsvaga zuva.
Zvisinei, inorondedzerwa neWorld Health Organization (WHO) se "isina kusimba" uye "zvichida chechigogoni kuvanhu" nokuti, mune zvakawanda zvakanyanya, zvidzidzo zvakaratidza kuti zvakonzera kenza mumakonzo. Zvakakosha kuziva, zvisinei, kuti izvo zvinonyanya kukoshesa hutachiona hwe WHO ndekudzivirira vashandi mumiti apo titanium dioxide yakaitwa.
Vashandi vacharatidzwa zvikwereti zvakanyanya, zvichida kuidzidzira, panguva yebasa ravo.
Izvo vashandi vanoda kudzivirirwa pane zvinokuvadza, kunyanya pakushanda nezvinhu zvakadai se titanium dioxide kwenguva refu. Hapana humwe uchapupu, zvisinei, kuti kushandiswa kwe titanium dioxide muzvishoma, zvakadai sekiki frosting kana mishonga, kunoita kuti vanhu vawedzere ngozi yekenza.
Studies on Titanium Dioxide uye IBD
Chimwe chidzidzo chakatarisa zvose zvinokonzera titanium dioxide yaiva mumakonzo akabatwa nehutachiona. Vatsvakurudzi vakashandisa kemikemikari pamakonzo kuti aite colitis, iyo inoreva kubhururuka mumakoloni uye haisi yakangofanana nechirwere chepachirwere sezvainozivikanwa nevanhu. Kunyengedza makonzo ane chirwere chinowanzoitwa mumhando idzi dzekutanga zvidzidzo, kuona kana paine chikonzero chekuenderera kuchidzidzo chikuru kana kuti kuenderera mberi nekutsvakurudza.
Zvakawanikwa mumakonzo aya ndezvokuti pavakange vane chirwere uye vakapiwa zvakakwana zve titanium dioxide zuva nezuva mumvura yavo (kana 50 mg kana 500 mg kilogram yehutatu hwehuviri), urwere hwakanyanya huchiwedzera. Mhuri dzakanga dzisina colitis uye dzakapiwa titanium dioxide dzakanga dzisina kuchinja mumakoloni avo. Saka vatsvakurudzi vakapedzisa, naizvozvo, kuti titanium dioxide ingangodaro inokuvadza kana pane ikozvino kuputika mukoni.
Chidzidzo ichocho chaivewo nechikamu chevanhu, uye vanhu vane Crohn's disease uye ulcerative colitis vakaidzidzwa. Zvakawanikwa nevatsvakurudzi ndezvokuti vanhu vane chironda chekuonda kwepachirwere mumarara - yakave vakawedzera kuwanda kwetatani muropa ravo. Vatsvakurudzi vakagumisa kuti kuva nekuputika mumakoloni kunoreva kuti mamwe titanium yakatorwa kumusoro uko ndokuzoita nzira yayo muropa. Tichifunga izvi, pamwe nemigumisiro kubva pane zvakaitika mumakonzo, vanyori vekudzidza vanoti migumisiro yavo inofanira kutitungamirira kuti tifunge "kushandiswa kwakanyanya kwezvikamu izvi."
Pakave nemimwe miedzo kune vanhu vane Crohn's disease, iyo yakadzidza kudya kwaisina nanoparticles. Chidzidzo chekutanga chakaitwa pavarwere makumi maviri vane chirwere chinoshanda uye vakaenda kwemwedzi mina. Varwere vaiva nechepasina chechikafu chekudya vaitoda kuita zviri nani kudarika izvo zvisiri pazvokudya. Mhedziso ndeyokuti kubvisa zvinyorwa zvezvokudya uye zvimwe zvinhu zvine microparticles kana nanoparticles, zvingabatsira.
Chechipiri, chidzidzo chakafanana chakaitwa nevarwere 83. Zvokudya zvakafanana zvakashandiswa, asi vatsvakurudzi havana kuuya kune imwecheteyo yekupedzisira: varwere vaiva pazvokudya havana kuita chero nani pane avo vakanga vasina kudya. Izvi zvinorevei kuti hakuna humwe humwe huchapupu hwakanaka hwekuchera zvinhu zvakadai sezvokudya zvinowedzera kune chinokonzera chirwere che Crohn. Icho chiitiko che "kudzokera kumugadziro" kune vatsvakurudzi.
Kuwedzeredza Sigma Inosangana Nezvokudya
Kune vanhu vane IBD, pane chokwadi chinonyadzisira chinosanganiswa nekudya. Shamwari, mhuri, uye vashandi pamwe chete vanogona kutarisa kubvunzurudzwa pane izvo munhu ane IBD anodya uye kutonga pamusoro pemigumisiro yekudya kune zviratidzo . Vanhu vane IBD vanowanzoziva kuti zvii zvinodyiwa zvinowanzova zvinonetsa uye mune dzimwe nguva, zvinogona kuva pane kudya kwechinguva kwechinguva. Avo vakambovhiyiwa mumatumbo avo kubata maBD avo uye avo vanogona kuwedzera kuvhara kungada kudzivisa zvimwe zvokudya kana mapoka ezvokudya zvachose.
Kutsvakurudza hakuna kuratidza, zvisinei, kuti kudya kunokonzera kana kunokonzera IBD. Varwere vanokurudzirwa kuti vadye sehutano hwekudya sezvinobvira, izvo zvinosanganisira michero nemiriwo. Kushanda nemudzidzisi wemhuka ane ruzivo mukurapa vanhu vane IBD kunobatsira kuti vadye kudya kunenge kusingobatsiri neBD chete asi kunewo mavitamini uye emaminera vanhu vane IBD inoda . Munguva yehutu-up, vanhu vazhinji vane IBD vanorega kudya, asi mamwe makoriri anodiwa panguva ino, kwete zvishoma.
Shoko Rinobva
Apo kuongororwa pamusoro peBD kunouya izvo zvinetso izvo zvatiri kuziva zvino kuti ndezvechokwadi, zvinogona kuzunungusa kugamuchirwa kwezvinhu zvose zvine chokuita nezvirwere izvi. Izvi ndezvechokwadi kunyanya nezvekutsvaga nezvekudya, uye izvo zvakasarudzwa-izvo zvingasave nekunzwisisana kweBD-zvinowanzovhiringidza. Zvidzidzo pamusoro peti titanium dioxide hazvina kuratidza kuti tinofanira kana kuti hatifaniri kufunganya pamusoro pekuwedzera kwezvokudya. Zvimwe zvokudya zvitsva uye zvokudya zvishomanana zvinogadzirwa zvinowanzova pfungwa yakanaka. Usati wadzvora zvokudya kunze zvachose, kunyange zvakadaro, pfungwa yakanakisisa ndeyokutaura ne gastroenterologist yako uye / kana nyanzvi yezvechirwere pamusoro pekuchengeteka, kunonwisa, uye zvinogona kusarudzwa.
> Sources:
> IARC Kushanda neChitatu cheKuongorora kweChitogenic Dambudziko kuvanhu. "Carbon yakasviba, titanium dioxide, uye talc." IARC monographs pakuongororwa kwevanhu vanokonzerwa necarcinogen. "World Health Organization, International Agency for Research on Cancer, Vol 93, 2010.
> Lomer MC, Grainger SL, Ede R, et al. "Kusakosha kwekuderedzwa kwema microparticle kudya mune imwe muedzo wevanorwara vane chirwere chinonzi Crohn's." Eur J Gastroenterol Hepatol. 2005; 17: 377-384.
> Lomer MC, Harvey RS, Evans SM, et al. "Kubudirira uye kushivirira kwechikafu chiduku chinokonzerwa nehupachiviriki mune zvakapetwa kaviri, randomized, pilot study muCrohn's disease." Eur J Gastroenterol Hepatol 2001; 13: 101-106.
> Ruiz PA, Morón B, Becker HM, et al. "Titanium dioxide nanoparticles inowedzera DSS-induced colitis: nhengo yeNLRP3 inoparmaome." Kubva 2017 Jul; 66: 1216-1224.
> Weir A, Westerhoff P, Fabricius L, Hristovski K, von Goetz N. "Titanium dioxide nanoparticles muzvokudya uye mishonga yekuchengetedza pachedu." Pakati peSci Technol 2012 Feb 21; 46: 2242-2250.