Unogona Kutya Kanzera Kufa Here?
Ko shuga inokonzera kenza here? Kana iwe uine kenza, shuga inogona kuita kuti ikure nokukurumidza? Uyu mubvunzo wakakosha, asi mhinduro haisi nyore.
Zvose zvemasero ako anoda glucose (shuga yeropa) yemasimba. Masero anopa utano anotevera hupenyu hwekukura, kugovana, nekufa. Sezvakaita mashizha pamuti, masero akare anofa uye anotsiviwa nenhamba yakaenzana yemasero ane utano.
Kanzera inokura kana masero ekare anoramba kufa asi anoramba achikura, achiparadzanisa, uye achivaka munzvimbo imwe-achiumba tumarara .
Ishu Inokonzera Kanzira Here?
Mhedziso yokuti masevhesi emukenza anowedzera mukushuga ave achinyanya kubva kubva pakabudiswa muna 1924 pepa Dr. Dr. Otto Warburg, Pamusoro peMetabolism Tumor. Warburg yaiva nyanzvi yezvigadzirwa zveNobel-Winning biologist iyo inofunga kuti kenza yekukura yakakonzerwa kana kenza yemasera inoshandura glucose muine simba pasina kushandisa oxygen. Ichi chaive chirevo chinonakidza, muchidimbu nokuti tinoziva kuti masero ane hutano anoita simba kuburikidza nekushandura pyruvate uye oksijeni. Iyo piritsi inokonzerwa mukati memasechondria eine utano. Sezvo kenza yemasero isingaiti oxidze pyruvate, Warburg inofunga kuti kenza inofanirwa kuonekwa sekushaya kwemitochondrial.
Asi haisi iyo iyo kenza inoshanda. Kanzira inokonzerwa nekuchinja kwemagetsi , kana kuchinja kwezvinhu zvakagadzirirwa nhaka, kana izvo zvinowanikwa nekufamba kwenguva kuburikidza nehutachiona hwemakemikari kana semugumisiro wekugadzikana kwemasero emasero.
Kunyange zvazvo masero ane utano nemasero emukenza anoshandura zvokudya zvavo kune simba nenzira dzakasiyana, iyo kusiyana kunokonzera , kwete chikonzero, chekenza. (Dzidza nezvekusiyana kwekenza masero nemasero akajairika .)
Shuga uye Hyperglycemia
Pasinei nekuwana kukanganisa mune shuga nekenza maitiro ekare, zvinoratidzika sehumwe hukama pakati pehuwandu hwemashuga uye kenza.
Zvinonyatsozivikanwa kuti vanhu vane chirwere cheshuga chechipiri vane huwandu hwehuwandu hwekenza dzakawanda. Zvakave zvichiratidzwawo kuti chirwere cheshuga chepamusoro chepamusoro chinogona kubatsira pakuumbwa kwekenza masero (oncogenesis), kushorwa kwechiremera kufa mumasero ekenza (apoptosis resistance) uye matumire kusagadzikana chemotherapy. Pasinei nokuti izvi zvinokonzera ne "kazhinji" yakasimudzirwa sutu yeropa, yakadai sekutevera dessert splurge vs chete kune avo vane insulin kushorwa uye yakakwirira sutu yeropa haisi chokwadi zvachose.
Shuga nemaProteine Chengetedza Kanera Maselo Akave
Zvave zvataurwa kuti masero ekenza haana kufa-haafi munzira yakarongeka semasero ane utano. Masayendisiti akadzidza izvi uye angave akawana kuti zviyero zvemasero zvinodini kuti zvirege kuchengetedza kero. Mukutsvakurudza kwebhishopi paDuke University, kenza yemaserini inoita sechishandisa kusanganiswa kweshuga uye mapuroteni chaiwo kuti arambe achikura paanofanira kufa. Aya masero emukenza anoita shandisa shuga pamwero wakakwirira, kuitira kuti usateerere mirayiridzo yemavara kuti ufe.
Kuvandudza Mutsva Mutsva-Akabatwa Kanzura Zvinodhaka
PaYunivhesiti yaJohn Hopkins, boka revatsvakurudzi rakatarisa nzira dzokunyengedza masero ekenza kukura zvishoma nezvishoma ndokuzozviuraya pachavo.
Vakadzidza kusagadzikana kweglycosylation -kuti kenza dzemasera dzinoisa shuga nemapuroteni pamwe chete kuti vararame. Apo masero aya aipiwa n -butyrate (munyu) nemakrobohydrates (yakaoma sutu), kukura kwavo kwakaderera. Kuti vafudze kenza chirwere chinouraya, vatsvakurudzi vakabudisa mamolekari e hybrid akaita soda yakasara uye n -butyrate. Nemhaka yekuti masero emukenza akavhara shuga nyore nyore, akadzikisa iyo molecules itsva, iyo yakavhiringidza kukwanisa kwavo kuramba vachikura, uye vakafa.
Mamwe mapoka emasayendisiti vari kushanda pamishonga inodhaka iyo inotora mukana wekushaya simba kwekenza yehuga.
Mimwe yemishonga mitsva inogona kupiwa pamwe chete nemakemikrasi, kuita kuti tumarara masero anzwe zvakanyanya kune chemo mishonga. MuSwitzerland, masayendisiti vari kushandisa shuga kupfeka "quantum dots" kana nanocrystals yemishonga inogona kuenda kuchiropa chete, kudzivisa dzimwe nhengo. Ndiyo shuga pane zviduku zviduku zvinobatsira mishonga kunyorera imwe chikamu chemuviri, nokudaro kuderedza migumisiro uye kuwedzera kushanda kwemishonga.
Kuneta neKenza
Imwe yenyefu muimba iyo painotaura nezve shuga uye kenza ndeyekurema. Kuva neino rinotapira nekudya zvinodyiwa zvega shuga zvakabatana nekurema, uye kuneta kunobatanidzwa nekenza. Kuwedzera muviri kunoshandura hutachiona hwemuviri mumuviri hunobatanidzwa nehutano hukuru hwevose varikukura nekenza uye vane chirwere chekenza kana kufambira mberi. Maererano neInternational Association for Research on Cancer, chimwe chezvinhu zvakanakisisa zvaunogona kuita zvose kudzivisa kenza panzvimbo yekutanga, uye kudzivirira kudzokorora kana iwe watoona kuti, inofanira kunge yakaoma sezvinobvira usina kuomesera.
Iva Smart Pamusoro peShuga Mune Zvokudya Zvako
Shuga inopa simba asi haisi kukupa chero mishonga inodiwa kuderedza kenza yako ngozi. Sirasi yemazuva ano inowanikwa muzvibereko nemichero yemisi uye inogona kuva chikamu chekudya kwakanaka. Wakawedzera shuga-rudzi rwakawedzerwa kuzvokudya panguva yekugadzirwa, zvakadai sehuga mutsvuku, shura yegorosi, uye chibereko chemuchero-inofanira kudziviswa kana kusagadzikana. Kunyanya kuwanda shuga makorikori kunogona kutungamirira kukurema uye yakakwirira insulin mazinga, izvo zvinogona kuita kuti kuwedzerwa kenza yenyu kuwedzere. Dzorera zvekudya zvakagadzirwa neshuga zvakadai samasipi, zvinhu zvakabikwa, zvimedu zvinotapira uye sodas kuderedza dambudziko rako rekenza. Edzai kudya kwenyu nemichero yezvirimwa, hove, uye zviyo zvakakwana -zvikamu zvekudya kwakanaka izvo zvakabatanidzwa nehuwandu hwehutano hwekenza.
The Bottom Line
Zvakanaka kudya zvimedu zvemashuga zvezuva nezuva, kunyanya kana dziri chikamu chezvokudya zvakasvibirira zvakadai semukaka kana michero. Shuga mukudya kwako haisi kukonzera kenza mutezo. Kutya nese masero ako e shuga haazourayi kana kudzivirira kenza. Kuchengetedza kudya kwezvokudya zvinovaka muviri uye kugara uchiita muviri kunogona kukupa uremu hwehutano hwakanaka uye hunowanzoita insulin. Ndiyo nzira inofadza yekuderedza kenza yako ngozi.
Sources:
Duan, W., Shen, X., Lei, J. et al. Hyperglycemia, Chinhu Chisingakanganwi MuKutanga Kwekenza. Biomedical Research International . 2014: 461917.
Kikkeri, R., Lepenies, B., Adibekian, A. et al. In Vitro Imaging uye Mu Vivo Chiropa Targeting neCarbohydrate Capped Quantum Dots. Nyaya yeAmerican Chemical Society . 2009. 131 (6): 2110-2.
Sampathkumar, S., Jones, M., Meledeo, M et al. Targeting Glycosylation Pathways uye Nhamba Yemajeri: Basa reSuar-Denderedzwa yeByyrate-Carbohydrate Cancer Prodrugs. Chemistry uye Biology . 2006. 13 (12): 1265-75.