Sei Creutzfeldt-Jakob Disease Kusiyana neAlzheimer's

Iyi Dambudziko Ndeye Dzimwe nguva Kunyengedzwa Kunonzi "Mad Cow Disease"

Chii Chinonzi Creutzfeldt-Jakob Disease (CJD)?

Creutzfeldt-Jakob (akadudzwa CROYZ-akanzwa YAH-cob) chirwere chisingawanzovi neurodegenerative brain disorder iyo inobata munhu mumwe chete mumamiriyoni. Icho chimwe chezvizhinji zvezvirwere zvepachioni.

CJD inogonawo kutumidzwa seinoshandiswa spongiform encephalopathy, vCJD, uye Jacob-Creutzfeldt chirwere.

Kuwanda

IUnited States ine mamiriyoni mazana maviri kusvika ku300 pagore.

Avhareji yemakore ekutanga kune makore makumi matanhatu.

Zviratidzo zveCJD

Zviratidzo zvekare kare zvinosanganisira kuora mwoyo-kufanana nekusiya, mafungiro anochinja uye kusava nehanya kwevanhu kana mamiriro ezvinhu. Nokukurumidza, zvimwe zviratidzo zvinokura, kusanganisira zvinetso zvepfungwa , kuchinja mukuzvibata, kusawirirana kusina kunaka, kusafamba kwakasimba uye kutadza kuona.

Sezvo chirwere ichi chiri kuramba chichifambira mberi, vanhu vane CJD vanogona kuwana mazano , psychosis, kuora kwekubatana, kusununguka kwezvibvumirano, maoko asina simba zvakasimba uye makumbo, kusagona kukwanisa kumedza uye kutaura, uye kuwedzera kukanganisika kwepfungwa. Pakupedzisira, munhu wacho angangopinda mu coma.

Zvikamu zveCJD

• Sporadic
  Sporadic CJD inokwana anenge 85% yezviitiko zvose zvechirwere. Kupora zvinoreva kuti hapana chikonzero chakajeka.

• Hereditary
  Maererano neNational Institute of Neurological Disorders uye Stroke, maitiro akagara nhaka anotarisa anenge 5% kusvika 10% muzana. Iyo prion protein geni inenge isingawanzoitiki kuvanhu vane marudzi ose eCJD. Mune varwere vane fomu yemhuri, kuchinja-shanduka kwakawanikwa mu prion protein gene inokonzera mapuroteni asina kunaka. Vanhu ava vanowanzoratidza nhoroondo yemhuri yehutachiona.

• Akawana
  Kune zvitatu zvekuwana CJD. Izvi zvinosanganisira:

1. Iatrogenic
   Izvi zvinoreva CJD iyo inobvumiranwa kuburikidza nehutano, zvakadai sezviridzwa zvisingaiti kana kutapukira kwetachiona.
2. Kuru
   CJD inogona kuwanikwa kuburikidza nekudya nyama, iyo inonzi inonzi Kuru. Izvi zvakadzokera kuma1950, apo vanhu vedudzi Rokutanga muPapua, New Guinea vakagadzira mamiriro akawanda eCJD nokuti mariro yavo yaisanganisira vakadzi nevana vanodya bhudzi hwevakafa. Sezvo tsika iyo yanyarara, matanho eCJD akaderera, asi izvi zvakatora makore akawanda nokuti nguva yekudzivirira kweCJD inoratidzika kuva yakareba makore makumi mana.

1. Variant
   Kusiyana kweCJD kunofungidzirwa kunokonzerwa nekudya nyama yakatapukirwa uye inogona kuitika kune vaduku, nezera rinowanikwa makore ekutanga rinowanikwa pa 28. Izvi zvinowanzoreva zvisina kunaka kuti chirwere chemhou kana bovine spongiform encephalopathy. Chirwere chemadha chinowanikwa mumhou chete; apo inoparidzirwa kune vanhu, inonzi inonzi CJD yakasiyana. Rudzi urwu rweCJD haruwaniki; nyaya nhatu chete dzakanyorwa muUnited States, uye mbiri dzevaya vakanga vambova kunze kwenyika.

Kuongororwa CJD

Kungofanana nedzimwe nharo dzinokonzerwa neurological, hapana kuedza kwakajeka kuongorora CJD. Chinangwa chokutanga chechiremba ndechekutonga kune dzimwe mamiriro ezvinhu angangodaro anokonzera chirwere chekushaya mungozo, kunyanya nokuti zvimwe zvinokonzera demoenti zvinodzokororwa, zvakadai sekushandiswa kwemazuva ose ekudzvinyirira hydrocephalus uye kushaikwa kwevitamini B12 .

Miedzo yakadai sedwonzi remupopu , EEG , CT , uye MRI inogona kushandiswa kutsvaga mukana weCJD.

Kuti asimbise kuongororwa, vanachiremba vanogona kuita bhizimusi nokubvisa chikamu chiduku cheuropi kuti chiedze. Icho chimwe sarudzo ndeyokutungamira an autopsy mushure mekufa. Nebiopsy uye autopsy, kune njodzi yokuti chiremba anokwanisa kuitapukirwa neCJD paanenge achitarisira mhando dzehupi. Mukusiyana kweCJD, pane zviitiko zvakasimbiswa zvichitevera kubviswa uye kuongororwa kwematoni evanhu.

Saka zvakakosha zvikuru kuti kutarisirwa kwakakodzera kuitwe panguva yekuita.

CJD yakasiyana sei neAlzheimer's?

Kufambira mberi kweCJD kwakakurumidza kudarika muAlzheimer's disease . Vanhu vane CJD vanowanzofa mukati memavhiki mashoma kusvika kune rimwe gore. MuAlzheimer's, pane kazhinji kunonoka kuderera pamusoro pemakore akawanda.

Kurapa kweCJD

Pari zvino, hapana mushonga weCJD, kunyange zvazvo zvimwe zviratidzo zvinogona kubviswa nemishonga. Chinangwa ndechokupa nyaradzo uye zororo. Kutsvakurudza kunoramba kuchiitwa pakuziva zvinokonzera uye pamwe nekugona mishonga yekurapa CJD.

_Sources:

_{ADAM Creutzfeldt-Jakob Disease.Akapedza February 10, 2012. http://adam.about.net/encyclopedia/infectiousdiseases/Creutzfeldt-Jakob-disease.htm}

_{Alzheimer's Association. Creutzfeldt-Jakob Disease. Yakasvika musi waFebruary 10, 2012. http://www.alz.org/alzheimers_disease_creutzfeldt_Jakob_disease.asp}

_{Creutzfeldt-Jakob Disease Foundation, Inc. CJD Dhiyabhorosi Sheet. Yakasvika musi waFebruary 10, 2012. http://www.cjdfoundation.org/fact.html}

_{Creutzfeldt-Jakob Disease Foundation, Inc. Creutzfeldt-Jakob Zvirwere nezvimwe zvirwere zve Prion. Yakasvika musi waFebruary 10, 2012. http://www.cjdfoundation.org/pamphlets.html}

_{World Health Organization. Creutzfeldt-Jakob chirwere. Yakasvika musi waFebruary 10, 2012. http://www.who.int/topics/creutzfeldtjakob_syndrome/en/}