Penicillin uye mishonga inorwisa mabhakitiriya ndeimwe yekare uye inowanzoshandiswa mishonga inorwisa mabhakitiriya inowanikwa. Vari kushingaira kurwisa zvirwere zvakasiyana-siyana, hazvina mari, uye zvinowanzoremeswa. Zvinosuruvarisa, penicillin zvirwere zvakanyanya, uye 10% yehuwandu hwehuwandu hwehuwandu hwehutano hwemishonga iyi. Zvidzidzo zvinoratidza, asi, kuti apo vanhu vanorondedzera kuva yeergoric penicillin vanoongororwa kuti vawane zvirwere, anenge 90% haasi osegeri, uye vanogona kutora mishonga yacho zvakanaka.
Izvi kazhinji nokuti izvi zvinowanzoitika kwenguva pfupi.
Kuongororwa kwepenicillin allergy kunowanika, inzira inoratidzika nyore, uye kazhinji inotungamirira kumunhu aifunga kuti aine allergen penicillin kuti aone kuti haasi kunyanya kurwisa mishonga inorwisa mabhakitiriya, kana kuti haasisiri kurwara. Vakawanda vezvenergist vanokwanisa kukwanisa kupedza penicillin zvirwere zvekuongorora.
Kudzivisa Penicillin Kunogona Kutungamirira Kune Zvimwe Zvinetso
Vanhu vazhinji vane penicillin zvinorambidza kungorega kutora penicillin uye mamwe maitiro anorwisa mabhakitiriya, sezvo pane zvimwe zvakasiyana-siyana zvemishonga inorwisa mabhakitiriya inotora chirwere chinoitika. Asi iyi ndiyo nzira yakarurama yekutora? Ongororo dzakasiyana-siyana dzinoratidza kuti kana munhu akanyorwa se penicillin anyergic, zvinetso zvakawanda zvinogona kubuda semugumisiro wokupiwa mamwe maantibioti.
Chokutanga, mari yekutora non-penicillin antibiotic inokura zvikuru. Ongororo dzinoratidza kuti chiyero chemari inorwisa mabhakitiriya mumunhu ane penicillin allergy ndeye 63% kupfuura kune avo vasina penisilini.
Chechipiri, kushandiswa kwevanhu vasina penicillin mishonga inorwisa mabhakitiriya, kunyanya muchipatara, inoisa munhu pangozi yekuvandudzwa kwezvirwere nema antibiotic asingagadziri mabhakitiriya, zvakadai sevancomycin-resistant-resistococcus (VRE) . Pakupedzisira, kushandiswa kwevanhu vasina penicillin mishonga inorwisa mabhakitiriya kunogonawo kuisa munhu pangozi yakakwirira yekukudziridza Clostridium difficile colitis , utachiona hwehutachiona hwomukati hunokonzerwa nekushandiswa kwemishonga inorwisa mabhakitiriya.
Kushandiswa kwe penicillin kuongororwa kwevanhu muvanhu vanotaura nhoroondo yepenicillin zvirwere zvakaratidzwa mune dzakawanda zvidzidzo zvekugura kushandiswa kwemasimba anorema, anodhura anodarika akawanda. Zvimwe zvidzidzo zvakaratidza kuti kuburikidza nokushandiswa kwe penicillin kuongororwa kwemawere, mari yekurapa maantibayotiki kurapa zvirwere zvinodonha neanopfuura 30%.
Penicillin Izvo Zvakanaka Pakubvisa Allergic Reactions
Penicillin inokwanisa kukonzera nyore nyore allergic reactions kuvanhu nekuda kwekukwanisa kwayo kusunga mapuroteni muropa uye pamasero ari mumuviri kuitira kukurudzira masimba ezvirwere. Izvi, zvinonzi huteni, zvinotungamirira mumuviri wemuviri kuti uve nani pakunzwisisa penicillin sechirwere. Kuchengetedza , kana kukura kwezvirwere zvinokonzerwa nemagetsi, penicillin zvinobva zvaitika, izvo zvinogona kutungamirira kugadziriswa kwevanhu kana munhu achinzwa penicillin munguva yemberi.
Zvikamu zvePenicillin Allergy Test
Penicillin allergy test inosanganisira kushandiswa kwemhando dzakasiyana-siyana dzekuongorora kweganda, kusanganisira prick skin test uye intradermal kuedzwa kweganda , penicillin uye penicillin metabolites. Vazhinji vanachiremba vanoita zvekucheneswa kweganda ne penicillin G (injectable form penicillin inenge iri mumvura), Pre-Pen (benzylpenicilloyl polylysine) - iyo yakakura metabolite penicillin mushure mekunge muviri uchinge waputsa mutachiona, uye musanganiswa muduku wechidiki (MDM ) ine zvimwe "zviduku" metabolites.
MDM haisi kuwanikwa mune zvekutsvaga panguva ino, kunyange vamwe vese allergists - zvakadai sevaya vari kushanda mumayunivhesiti - vachaita "chivakwa" version. Penicillin kuongorora iyo inosanganisira kushandiswa kweMDC kunowedzera kuenzana kwekuedzwa.
Kuongorora zvirwere zveArgyergy zvinowanikawo ku penicillin kuongororwa kwemishonga, asi haisi yakarurama kwazvo, uye kazhinji haafaniri kushandiswa sechinotsiva penicillin kurwara kwepachiedza.
Iyo Penicillin Allergy Testing Inogadzirwa
Kazhinji, kuongorora kweganda kunoshandiswa kutanga, iyo inokwanisa kuziva penicillin yakaoma zvikuru-inokonzera vanhu.
Kana kuvharwa kweganda kuongorora kunofadza, zvino munhu wacho anonzi anoregic penicillin, uye hapana kuwedzerwa kunoitwa. Kana kunyanya kuongorora kusina kunaka, iyo inonzi intradermal yero yekutengesa inoitwa pamwe chete nezvinhu zvakafanana. Intradermal kuedza kweganda kunotsanangura vanhu vakawanda vane penicillin allergy asi zvinogona kuva nengozi kune vanhu vane hanya zvikuru. Ichi ndicho chikonzero nei kuvharwa kweganda kunoshandiswa kutanga.
Kana kugadzirwa kweganda ku penicillin uye nemasabolite akafanana kusina kushandisa maitiro ekutanga uye emadzinza, ipapo mukana wekuti munhu anenge aine penicillin ari pasi pe5%. Vakawanda vanachiremba vanobva vachinzwa vakasununguka kutsanangura penicillin uye antiicticin-inoratidzira antibiotics kumunhu iyeye, kunyange zvazvo vamwe vanachiremba (kusanganisira ini) vachiri kukurudzira kupa chiremba chekutanga penicillin pasi pekutarisirwa kweutano, uye kutarisa kweawa kana maviri. Ini ndinototanga kuwedzera danho uye ndinopedza kunyora penicillin antibiotic (kazhinji amoxicillin) pasi pekutarisirwa kwehutano kuti ave nechokwadi chokuti munhu anokwanisa kutsungirira mishonga inorwisa mabhakitiriya.
Kana chimwe chezviongororwa zvataurwa pamusoro apa chakanaka, ipapo munhu anofanira kuzviona achizviisa kune penicillin. Mune mamiriro ezvinhu, penicillin uye mamwe maitiro anonzi antibiotics anofanirwa kudziviswa, kunze kwekunge pane zvinodiwa zvepenicillin - uye kushandiswa kwemamwe maantibayoti hazvikwanisi. Kuora mwoyo kune penicillin kunogona kuitwa, pane dzimwe nguva mune hofisi yehutano, asi kazhinji munzvimbo yezvipatara, kuitira kuti munhu anokwanisa kutsungirira nzira ye penicillin. Zvakakosha kuziva, zvisinei, kuti kuora mwoyo kunongogara kwemazuva mashomanana, saka kuora mwoyo hakusi kutungamirira kune chirwere chekurwisa, asi kungove nekutsungirira kwenguva pfupi yemishonga.
Verenga zvakawanda pamusoro pemishonga inorwisa mabhakitiriya inofanira kudziviswa ne penicillin .
> Sources:
> Pre-Pen Package Insert. ALK-Abello. Website Yakawanikwa KuJanuary 31, 2016.
> Fox S, Park M. Penicillin Ganda Kuongororwa Mukuongorora nekutariswa kwePenicillin Allergy. Ann Allergy Chirwere Immunol. 2011; 106: 1-7.
> Nugent JS, Quinn JM, McGrath CM, et al. Kutsunga Kwekuitika kweSensitization Mushure mePenicillin Ganda Kuongorora. Ann Allergy Chirwere Immunol. 2003: 90: 398-403.